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JOURNAL ARTICLE
Jonathan Staloff, Eric Gunnink, Jorge Rojas, Edwin S Wong, Karin Nelson, Ashok Reddy
BACKGROUND: The Veterans Health Administration increased synchronous telemedicine (video and telephone visits) in primary care in response to the COVID-19 pandemic. OBJECTIVE: Our objective was to determine veteran use patterns of in-person and telemedicine primary care when all modalities were available. DESIGN: A retrospective cohort analysis. We performed a latent class analysis of primary care visits over a 1-year period to identify veteran subgroup (i...
April 15, 2024: Journal of General Internal Medicine
#2
JOURNAL ARTICLE
Lucas Lemarié, Edwin-Joffrey Courtial, Jérôme Sohier
Stem cell spheroids are rapidly becoming essential tools for a diverse array of applications ranging from tissue engineering to 3D cell models and fundamental biology. Given the increasing prominence of biotechnology, there is a pressing need to develop more accessible, efficient, and reproducible methods for producing these models. Various techniques such as hanging drop, rotating wall vessel, magnetic levitation, or microfluidics have been employed to generate spheroids. However, none of these methods facilitate the easy and efficient production of a large number of spheroids using a standard 6-well plate...
April 5, 2024: Bio-protocol
#3
Dávid Deritei, Hiroyuki Inuzuka, Peter J Castaldi, Jeong Hyun Yun, Zhonghui Xu, Wardatul Jannat Anamika, John M Asara, Feng Guo, Xiaobo Zhou, Kimberly Glass, Wenyi Wei, Edwin K Silverman
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. The primary causes of COPD are environmental, including cigarette smoking; however, genetic susceptibility also contributes to COPD risk. Genome-Wide Association Studies (GWASes) have revealed more than 80 genetic loci associated with COPD, leading to the identification of multiple COPD GWAS genes. However, the biological relationships between the identified COPD susceptibility genes are largely unknown. Genes associated with a complex disease are often in close network proximity, i...
April 1, 2024: bioRxiv
#4
JOURNAL ARTICLE
Weronika O Razmus, Felix Allum, James Harries, Yoshiaki Kumagai, Kiyonobu Nagaya, Surjendu Bhattacharyya, Mathew Britton, Mark Brouard, Philip H Bucksbaum, Kieran Cheung, Stuart W Crane, Mizuho Fushitani, Ian Gabalski, Tatsuo Gejo, Aaron Ghrist, David Heathcote, Yasumasa Hikosaka, Akiyoshi Hishikawa, Paul Hockett, Ellen Jones, Edwin Kukk, Hiroshi Iwayama, Huynh V S Lam, Joseph W McManus, Dennis Milesevic, Jochen Mikosch, Shinichirou Minemoto, Akinobu Niozu, Andrew J Orr-Ewing, Shigeki Owada, Daniel Rolles, Artem Rudenko, Dave Townsend, Kiyoshi Ueda, James Unwin, Claire Vallance, Anbu Venkatachalam, Shin-Ichi Wada, Tiffany Walmsley, Emily M Warne, Joanne L Woodhouse, Michael Burt, Michael N R Ashfold, Russell S Minns, Ruaridh Forbes
C-I bond extension and fission following ultraviolet (UV, 262 nm) photoexcitation of 2- and 3-iodothiophene is studied using ultrafast time-resolved extreme ultraviolet (XUV) ionization in conjunction with velocity map ion imaging. The photoexcited molecules and eventual I atom products are probed by site-selective ionization at the I 4d edge using intense XUV pulses, which induce multiple charges initially localized to the iodine atom. At C-I separations below the critical distance for charge transfer (CT), charge can redistribute around the molecule leading to Coulomb explosion and charged fragments with high kinetic energy...
April 15, 2024: Physical Chemistry Chemical Physics: PCCP
#5
JOURNAL ARTICLE
Lucy Goodfellow, Edwin van Leeuwen, Rosalind M Eggo
BACKGROUND: The COVID-19 pandemic resulted in major inequalities in infection and disease burden between areas of varying socioeconomic deprivation in many countries, including England. Areas of higher deprivation tend to have a different population structure-generally younger-which can increase viral transmission due to higher contact rates in school-going children and working-age adults. Higher deprivation is also associated with a higher presence of chronic comorbidities, which were convincingly demonstrated to be risk factors for severe COVID-19 disease...
April 15, 2024: BMC Medicine
#6
JOURNAL ARTICLE
Marisa G Stahl, Zhaoxing Pan, Monique Germone, Sadie Nagle, Pooja Mehta, Mary Shull, Isabel Griffith, Brianne Shuler, Edward Hoffenberg, Iman Taki, Cristy Geno-Rasmussen, Marian J Rewers, Jill M Norris, Edwin Liu
BACKGROUND: Celiac disease (CD) mass screening remains controversial in part because of a paucity of data to support its benefit. The Autoimmunity Screening for Kids (ASK) study is a mass screening study for pediatric CD and type 1 diabetes in Colorado. METHODS: This study prospectively follows children ages 1-17 years who screened positive for tissue transglutaminase IgA autoantibodies (tTGA) in the ASK study subsequently referred for diagnostic evaluation. Children diagnosed with CD by biopsy or serologic criteria were included in this study...
April 12, 2024: Clinical Gastroenterology and Hepatology
#7
JOURNAL ARTICLE
Bibha Simkhada, Edwin Van Teijlingen, Chandrakala Sharma, Apsara Pandey, Padam Simkhada
The nursing and midwifery profession needs to stay up to date with the latest developments. In this Viewpoint, we shall be referring to 'nurses' and 'nursing' to mean 'nurses and midwives' and 'nursing and midwifery' respectively. Nurses must continue to update their skills and competences to meet changing future population health needs effectively and safely. However, the reality is that many staff are reporting difficulty accessing and completing Continuing Professional Development (CPD) in all settings...
March 22, 2024: Journal of Nepal Health Research Council
#8
JOURNAL ARTICLE
Verónica Rivas-Alonso, Jairo Cáceres, Edwin Ramírez-Benítez, Rodolfo Solís-Vivanco
INTRODUCTION: Cognitive impairment has a substantial impact on the daily function of people living with demyelinating diseases. However, the study of cognitive failures and their association with clinical variables in people suffering from neuromyelitis optica spectrum disorder (NMOSD) has been scarce, especially in the latin american (Mexican) population at early and middle stages of the disease. METHOD: We applied the Rao's Brief Repeatable Battery of Neuropsychological tests and obtained data of lesion burden through magnetic resonance imaging (MRI), expression of AQPQ4-IgG antibodies, and degree of disability in 30 patients with NMOSD and 30 healthy participants as a control group...
April 8, 2024: Multiple Sclerosis and related Disorders
#9
JOURNAL ARTICLE
Jose D Bermúdez-Perez, Edwin Herrera-Vasco, Javier Casas-Salgado, Hector A Castelblanco, Karen Vega-Bustos, Gabriel Cardenas-Chirivi, Oscar L Herrera-Sandoval, Hermann Suderow, Paula Giraldo-Gallo, Jose Augusto Galvis
We present the design, fabrication and discuss the performance of a new combined high-resolution Scanning Tunneling and Thermopower Microscope (STM/SThEM). We also describe the development of the electronic control, the user interface, the vacuum system, and arrangements to reduce acoustical noise and vibrations. We demonstrate the microscope's performance with atomic-resolution topographic images of highly oriented pyrolytic graphite (HOPG) and local thermopower measurements in the semimetal Bi2 Te3 . Our system offers a tool to investigate the relationship between electronic structure and thermoelectric properties at the nanoscale...
April 9, 2024: Ultramicroscopy
#10
JOURNAL ARTICLE
Lauren Ka Shun Lei, Yi Nam Suen, Christy Lai Ming Hui, Sherry Kit Wa Chan, Edwin Ho Ming Lee, Wong Tak Hing Michael, Eric Yu Hai Chen
OBJECTIVE: This study investigated changes in mental health in Hong Kong over two years and examined the role of resilience and age in mitigating the negative effects of public health emergencies, particularly the COVID-19 pandemic. METHODS: Complete data of interest from two telephone surveys conducted in 2020 (n = 1182) and 2021 (n = 1108) were analysed. Participants self-reported depressive and anxiety symptoms using the Patient Health Questionnaire 4-item version (PHQ), psychotic-like experiences (PLEs) using three items from the Prodromal Questionnaire Brief (PQB), and resilience using the Connor-Davidson Resilience Scale 2-item version (CD-RISC-2)...
April 2024: International Journal of Geriatric Psychiatry
#11
JOURNAL ARTICLE
Sara Temelkova, Saria Lofton, Elaine Lo, Jeannine Wise, Edwin K McDonald
It is well known that dietary choices impact both individual and global health. However, there are numerous challenges at the personal and systemic level to fostering sustainable healthy eating patterns. There is a need for innovative ways to navigate these barriers. Food as Medicine (FM) and Culinary Medicine (CM) are approaches to helping individuals achieve healthier diets that also recognize the potential to alleviate the burden of chronic diseases through healthy eating. Teaching kitchens, which offer an interactive environment for learning nutrition and cooking skills, are valuable educational tools for FM and CM interventions...
March 27, 2024: Nutrients
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JOURNAL ARTICLE
Greta Bischof, Edwin Januschewski, Andreas Juadjur
(1) Background: The authenticity of eggs in relation to the housing system of laying hens is susceptible to food fraud due to the potential for egg mislabeling. (2) Methods: A total of 4188 egg yolks, obtained from four different breeds of laying hens housed in colony cage, barn, free-range, and organic systems, were analyzed using 1 H NMR spectroscopy. The data of the resulting 1 H NMR spectra were used for different machine learning methods to build classification models for the four housing systems. (3) Results: The comparison of the seven computed models showed that the support vector machine (SVM) model gave the best results with a cross-validation accuracy of 98...
April 3, 2024: Foods (Basel, Switzerland)
#13
JOURNAL ARTICLE
Jacob Nignan Nabei, Harriet Affran Bonful, Edwin Andrews Afari, Abdul Gafaru Mohammed, Adote Anum
BACKGROUND: Tuberculosis (TB) and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) co-morbidity continues to be a serious worldwide health issue, particularly in Sub-Saharan Africa. Studies on the quality of life (QOL) of TB/HIV co-infected patients guide stakeholders on the delivery of patient-centred healthcare. This study evaluated QOL of TB/HIV co-infected individuals and its contributing factors. METHODS: We conducted a cross-sectional study among TB/HIV co-infected patients, receiving treatment at clinics in the Northern Region of Ghana...
April 12, 2024: BMC Infectious Diseases
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JOURNAL ARTICLE
Rhea J Longley, Josephine Malinga, Eva Hesping, Edwin Sutanto, Sophia M DonVito, Michal Kucharski, Damian A Oyong, Julie M J Verhoef, Esrah Du, Elizabeth Villasis, Kioko Mwikali
No abstract text is available yet for this article.
April 11, 2024: Trends in Parasitology
#15
JOURNAL ARTICLE
Sheraz Yaqub, Bjørn Edwin, Zane Hammoud, Gabriel Herrera-Almario, Buthaina Jabir, Kristoffer Lassen, Pål-Dag Line, Miguel Angel Lopez-Gonzalez, Michael Puttick, Mohammed Ahmed Idrees Saadelnour, José Sampaio-Neto, Raghuram Sampath, Konstantin V Sementsov, Ajith K Siriwardena, Ernesto Sparrelid, Alberto Büge Stein, Robert Sutcliffe, Helena Taflin, Hany Takla, Silvio Valdec, Cherisse N Vinoya, Waleed Zaid, Stephen J Wigmore
No abstract text is available yet for this article.
April 3, 2024: British Journal of Surgery
#16
JOURNAL ARTICLE
Surya Mitra Ayalasomayajula, Daniel Cogswell, Debbie Zhuang, R Edwin García
The electrochemical response characteristics of existing and emerging porous electrode theory (PET) models was benchmarked to establish a common basis to assess their physical reaches, limitations, and accuracy. Three open source PET models: dualfoil, MPET, and LIONSIMBA were compared to simulate the discharge of a LiMn2 O4 -graphite cell against experimental data. For C-rates below 2C, the simulated discharge voltage curves matched the experimental data within 4% deviation for dualfoil, MPET, and LIONSIMBA, while for C-rates above 3C, dualfoil and MPET show smaller deviations, within 5%, against experiments...
April 15, 2024: Heliyon
#17
JOURNAL ARTICLE
Adam G Culvenor, Thomas J West, Andrea M Bruder, Mark J Scholes, Christian J Barton, Ewa M Roos, Edwin H G Oei, Steven M McPhail, Richard B Souza, Jusuk Lee, Brooke E Patterson, Michael A Girdwood, Jamon L Couch, Kay M Crossley
OBJECTIVES: The study aims to (1) report the process of recruiting young adults into a secondary knee osteoarthritis prevention randomised controlled trial (RCT) after anterior cruciate ligament reconstruction (ACLR); (2) determine the number of individuals needed to be screened to include one participant (NNS) and (3) report baseline characteristics of randomised participants. METHODS: The SUpervised exercise-therapy and Patient Education Rehabilitation (SUPER)-Knee RCT compares SUPER and minimal intervention for young adults (aged 18-40 years) with ongoing symptoms (ie, mean score of <80/100 from four Knee injury and Osteoarthritis Outcome Score subscales (KOOS4 )) 9-36 months post-ACLR...
2024: BMJ Open Sport & Exercise Medicine
#18
JOURNAL ARTICLE
Victor W Li, Jaspreet Sahota, Deea K Dev, Dib D Gill, Vanessa C Evans, Auby Axler, Trisha Chakrabarty, André Do, Kamyar Keramatian, John-Jose Nunez, Edwin M Tam, Lakshmi N Yatham, Erin E Michalak, Jill K Murphy, Raymond W Lam
BACKGROUND: e-Health tools using validated questionnaires to assess outcomes may facilitate measurement-based care for psychiatric disorders. MoodFX was created as a free online symptom tracker to support patients for outcome measurement in their depression treatment. We conducted a pilot randomized evaluation to examine its usability, and clinical utility. METHODS: Patients presenting with a major depressive episode (within a major depressive or bipolar disorder) were randomly assigned to receive either MoodFX or a health information website as the intervention and control condition, respectively, with follow-up assessment surveys conducted online at baseline, 8 weeks and 6 months...
April 11, 2024: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
#19
JOURNAL ARTICLE
Karin Persson, Maria L Barca, Trine Holt Edwin, Lena Cavallin-Eklund, Gro Gujord Tangen, Hanneke F M Rhodius-Meester, Geir Selbæk, Anne-Brita Knapskog, Knut Engedal
BACKGROUND AND PURPOSE: The aims were to compare the novel regional brain volumetric measures derived by the automatic software NeuroQuant (NQ) with clinically used visual rating scales of medial temporal lobe atrophy (MTA), global cortical atrophy-frontal (GCA-f), and posterior atrophy (PA) brain regions, assessing their diagnostic validity, and to explore if combining automatic and visual methods would increase diagnostic prediction accuracy. METHODS: Brain magnetic resonance imaging (MRI) examinations from 86 patients with subjective and mild cognitive impairment (i...
February 2024: Brain and Behavior
#20
MULTICENTER STUDY
Marianna Adamo, Giulio Russo, Matteo Pagnesi, Edoardo Pancaldi, Hannes Alessandrini, Martin Andreas, Luigi P Badano, Daniel Braun, Kim A Connelly, Paolo Denti, Rodrigo Estevez-Loureiro, Neil Fam, Mara Gavazzoni, Rebecca T Hahn, Claudia Harr, Joerg Hausleiter, Dominique Himbert, Daniel Kalbacher, Edwin Ho, Azeem Latib, Edith Lubos, Sebastian Ludwig, Laura Lupi, Philipp Lurz, Vanessa Monivas, Georg Nickenig, Daniela Pedicino, Giovanni Pedrazzini, Alberto Pozzoli, Denise Pires Marafon, Roberta Pastorino, Fabien Praz, Joseph Rodes-Cabau, Christian Besler, Anne Rebecca Schöber, Joachim Schofer, Andrea Scotti, Kerstin Piayda, Horst Sievert, Gilbert H L Tang, Alessandro Sticchi, David Messika-Zeitoun, Holger Thiele, Florian Schlotter, Ralph Stephan von Bardeleben, John Webb, Julien Dreyfus, Stephan Windecker, Martin Leon, Francesco Maisano, Marco Metra, Maurizio Taramasso
BACKGROUND: Data on the prognostic role of the TRI-SCORE in patients undergoing transcatheter tricuspid valve intervention (TTVI) are limited. OBJECTIVES: The aim of this study was to evaluate the performance of the TRI-SCORE in predicting outcomes of patients undergoing TTVI. METHODS: TriValve (Transcatheter Tricuspid Valve Therapies) is a large multicenter multinational registry including patients undergoing TTVI. The TRI-SCORE is a risk model recently proposed to predict in-hospital mortality after tricuspid valve surgery...
April 8, 2024: JACC. Cardiovascular Interventions
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