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https://www.readbyqxmd.com/read/28730260/longer-survival-of-a-patient-with-glioblastoma-resected-with-5-aminolevulinic-acid-5-ala-guided-surgery-and-foreign-body-reaction-to-polyglycolic-acid-pga-suture
#1
Raluca Maria Munteanu, Lucian Eva, Bogdan IonuŢ DobrovăŢ, Alin Constantin Iordache, Liviu Pendefunda, Nicoleta Dumitrescu, Doina Mihăilă, Cristina Maria Gavrilescu, Elena Şapte, Ion Poeată
In recent years, there is a growing evidence that using 5-aminolevulinic acid (5-ALA)-guided resection of a cerebral glioblastoma, associated with chemoradiotherapy determine a prolonged survival of these patients, even though this period do not exceed 15 months. 5-ALA is a natural biochemical precursor of heme that is metabolized to fluorescent porphyrins, particularly protoporphyrin IX (PPIX) and no foreign reaction were noted until now. However, foreign body reaction developing in neurosurgery is documented in a few number of cases to suture material, surgical hemostatic material, or surgical glove starch, but up to now we could not find any article about granulomatous inflammation to polyglycolic acid (PGA) suture after brain tumor resection...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28728837/epileptic-apnea-in-a-patient-with-inherited-glycosylphosphatidylinositol-anchor-deficiency-and-pigt-mutations
#2
Kosuke Kohashi, Akihiko Ishiyama, Shota Yuasa, Tomomi Tanaka, Kazushi Miya, Yuichi Adachi, Noriko Sato, Hirotomo Saitsu, Chihiro Ohba, Naomichi Matsumoto, Yoshiko Murakami, Taroh Kinoshita, Kenji Sugai, Masayuki Sasaki
We report an 11-month-old boy with acetazolamide-responsive epileptic apnea and inherited glycosylphosphatidylinositol (GPI)-anchor deficiency who presented with decreased serum alkaline phosphatase associated with compound PIGT mutations. The patient exhibited congenital anomalies, severe intellectual disability, and seizures, including epileptic apnea with epileptiform discharges from bilateral temporal areas. Brain magnetic resonance imaging revealed delayed myelination and progressive atrophy of the brainstem, cerebellum, and cerebrum...
July 17, 2017: Brain & Development
https://www.readbyqxmd.com/read/28728258/-follow-up-and-genetic-study-of-43-chinese-children-with-type-%C3%A2-alexander-disease
#3
T T Ban, Y Wu, Z B Zhang, L L Zang, J M Wang, Y W Jiang
Objective: To identify the clinical and genetic characteristics in 43 Chinese children diagnosed with type Ⅰ Alexander disease (AxD). Method: Forty-three type Ⅰ AxD cases identified by glial fibrillary acidic protein (GFAP) gene mutations in Peking University First Hospital from 2005 to 2016 were followed up. The data of medical history, physical examination and magnetic resonance imaging (MRI) were collected. All these patients were followed up in December 2010, Febury 2012, June 2014 and January 2016, respectively...
July 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28726560/bayesian-methods-for-addressing-long-standing-problems-in-associative-learning-the-case-of-pree
#4
Fernando Blanco, Joaquín Moris
Most associative models typically assume that learning can be understood as a gradual change in associative strength that captures the situation into one single parameter, or representational state. We will call this view single-state learning. However, there is ample evidence showing that under many circumstances different relationships that share features can be learned independently, and animals can quickly switch between expressing one or another. We will call this multiple-state learning. Theoretically, it is understudied because it needs a different data analysis approach from those usually employed...
July 20, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28725434/regression-of-multifocoal-in-transit-melanoma-metastases-after-palliative-resection-of-dominant-masses-and-2%C3%A2-years-after-treatment-with-ipilimumab
#5
Raphael B Moreira, Lana Hamieh, Evisa Gjini, Ana Lako, Katherine M Krajewski, Charles H Yoon, Patrick A Ott
BACKGROUND: Spontaneous regression of metastatic melanoma and delayed responses more than one year after treatment with ipilimumab are rarely seen. CASE PRESENTATION: Here, we present the case of a patient with in transit metastases from cutaneous melanoma on his right lower extremity who achieved complete regression of all metastatic lesions 13 months after the first of two consecutive palliative resections of dominant masses and more than two years after treatment with ipilimumab...
2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28725331/a-very-late-presentation-of-a-right-coronary-artery-occlusion-after-transcatheter-aortic-valve-replacement
#6
Roberto Ramirez, Oxana Ovakimyan, Glenmore Lasam, Kristen Lafferty
Involvement of the coronary ostia is a rare complication after transcatheter aortic valve replacement (TAVR). This complication has been more commonly described immediately after valve deployment. This is the first reported case of delayed coronary obstruction caused by TAVR 6 months after the procedure.
June 2017: Cardiology Research
https://www.readbyqxmd.com/read/28725244/optimal-perioperative-anesthesia-management-for-gynecologic-interstitial-brachytherapy
#7
Alison A Nielsen, Tehani A Liyanage, Gary S Leiserowitz, Jyoti Mayadev
PURPOSE: To propose an optimal perioperative pain management clinical care pathway for interstitial brachytherapy for gynecologic cancer based on our interdepartmental experience. MATERIAL AND METHODS: We conducted a retrospective review of 23 women who underwent 32 interstitial brachytherapy procedures for gynecological cancers, analyzing patient demographics, type of anesthetic, medications, postoperative pain scores, adverse events, and delays in discharge. We measured the association of postoperative nausea and/or vomiting (PONV) with hydromorphone use, and postoperative pain scores and total narcotic administration with type of anesthesia...
June 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28725155/a-case-of-severe-erythema-nodosum-induced-by-methimazole
#8
Selma Emre, Didem Ozdemir, Sibel Orhun, Goknur Kalkan, Sertac Sener
Erythema nodosum (EN), is the most common variant of septal panniculitis and is possibly a delayed hypersensitivity reaction triggered by a wide range of antigenic stimuli. Hypersensitivity reactions due to medications have been recognized as a cause of 3-10% of EN cases. Case reports of EN associated with the anti-thyroid drugs are quite rarely reported in the literature even if there is a common use of anti-thyroid drugs. We report an EN case due to methimazole. The complaints of patients arose immediately fifteen days after the beginning of methimazole treatment...
July 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28724436/expanding-the-phenotype-of-reciprocal-1q21-1-deletions-and-duplications-a-case-series
#9
Martina Busè, Helenia C Cuttaia, Daniela Palazzo, Marcella V Mazara, Salvatrice A Lauricella, Michela Malacarne, Mauro Pierluigi, Simona Cavani, Maria Piccione
BACKGROUND: Recurrent reciprocal 1q21.1 deletions and duplications have been associated with variable phenotypes. Phenotypic features described in association with 1q21.1 microdeletions include developmental delay, craniofacial dysmorphism and congenital anomalies. The 1q21.1 reciprocal duplication has been associated with macrocephaly or relative macrocephaly, frontal bossing, hypertelorism, developmental delay, intellectual disability and autism spectrum disorder. METHODS: Our study describes seven patients, who were referred to us for developmental delay/intellectual disability, dysmorphic features and, in some cases, congenital anomalies, in whom we identified 1q21...
July 19, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28721627/two-chinese-pedigrees-of-blau-syndrome-with-thirteen-affected-members
#10
REVIEW
Di Wu, Min Shen
Blau syndrome (BS) is a rare autosomal dominant autoinflammatory disease characterized by the clinical triad of dermatitis, arthritis, and uveitis. It is caused by mutations in nucleotide-binding oligomerization domain-containing protein-2 (NOD2) gene. BS has been widely reported in Caucasians but cases documented in China are scarce. We reported two Chinese families with BS, which were by far the two largest pedigrees in the Chinese population. We identified two unrelated families with BS. The phenotypes and genotypes of these patients were reviewed and compared with previous cohorts...
July 18, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28721218/spontaneous-reossification-of-the-sella-in-transsphenoidal-reoperation-associated-with-strontium-ranelate
#11
Maria Mercedes Pineyro, Daiana Arrestia, Mariana Elhordoy, Ramiro Lima, Saul Wajskopf, Raul Pisabarro, Maria Pilar Serra
Spontaneous reossification of the sellar floor after transsphenoidal surgery has been rarely reported. Strontium ranelate, a divalent strontium salt, has been shown to increase bone formation, increasing osteoblast activity. We describe an unusual case of a young patient with Cushing's disease who was treated with strontium ranelate for low bone mass who experienced spontaneous sellar reossification after transsphenoidal surgery. A 21-year-old male presented with Cushing's features. His past medical history included delayed puberty diagnosed at 16 years, treated with testosterone for 3 years without further work-up...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28719298/cognitive-outcomes-and-psychiatric-symptoms-of-retinopathy-positive-cerebral-malaria-cohort-description-and-baseline-results
#12
Rachel Brim, Sebastian Mboma, Margaret Semrud-Clikeman, Sam Kampondeni, Jed Magen, Terrie Taylor, John Langfitt
Cerebral malaria (CM) is a common cause of death and disability among children in sub-Saharan Africa. Many prior studies of neuropsychiatric morbidity have been limited by a cross-sectional design or a short duration of follow-up. Most have included subjects who may have presented with coma due to a disease process other than CM. No studies have assessed the relationship between magnetic resonance imaging (MRI) findings and long-term outcomes. The Cognitive Outcomes and Psychiatric symptoms of retinopathy-positive CM (COPS) cohort is the first large (N = 221) prospectively recruited cohort of stringently defined cases of CM and hospital-based, age-matched, non-CM controls in whom cognitive and psychiatric outcomes are assessed with standardized measures semi-annually for up to 5 years...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28717871/sleeve-gastrectomy-telementoring-a-sages-multi-institutional-quality-improvement-initiative
#13
Ninh T Nguyen, Allan Okrainec, Mehran Anvari, Brian Smith, Oz Meireles, Denise Gee, Erin Moran-Atkin, Evelyn Baram-Clothier, Diego R Camacho
BACKGROUND: Sleeve gastrectomy is a relatively new procedure that developed as a result of rapid innovation in the field of bariatric surgery. As with any newly developed operation, there is a learning curve that potentially can be associated with higher morbidity. Real-time surgical mentoring reduces the learning curve effect but can be time intensive for the mentor. The aim of this initiative was to evaluate the feasibility, effectiveness, and satisfaction of surgical telementoring for laparoscopic sleeve gastrectomy...
July 17, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28716448/textile-aging-characterization-on-new-generations-of-explanted-commercial-endoprostheses-a-preliminary-study
#14
A Bussmann, F Heim, C Delay, E Girsowicz, B Del Tatto, D Dion, J Papillon, A Lejay, J Chakfé, F Thaveau, Y Georg, N Chakfé
OBJECTIVE/BACKGROUND: The goal of the present study was to assess the aging phenomena on second-generation textile endoprostheses (EPs) through explant analysis and to establish a preliminary classification of observed defects and material damages. METHODS: From January 2011 to June 2016 110 second- and recent-generation EPs were collected as a part of a European collaborative retrieval program. The analysis focused on the first 41 consecutive commercial EPs collected between 2011 and 2014 and made from polyethylene terephthalate...
July 14, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28716097/regression-of-multifocoal-in-transit-melanoma-metastases-after-palliative-resection-of-dominant-masses-and-2%C3%A2-years-after-treatment-with-ipilimumab
#15
Raphael B Moreira, Lana Hamieh, Evisa Gjini, Ana Lako, Katherine M Krajewski, Charles H Yoon, Patrick A Ott
BACKGROUND: Spontaneous regression of metastatic melanoma and delayed responses more than one year after treatment with ipilimumab are rarely seen. CASE PRESENTATION: Here, we present the case of a patient with in transit metastases from cutaneous melanoma on his right lower extremity who achieved complete regression of all metastatic lesions 13 months after the first of two consecutive palliative resections of dominant masses and more than two years after treatment with ipilimumab...
July 18, 2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28712735/spontaneous-regression-of-post-traumatic-syringomyelia-a-case-report-and-literature-review
#16
Monish M Maharaj, Kevin Phan, Ralph Mobbs
Syringomyelia defines a condition in which myelopathy develops secondary to the formation of a cyst or cavity within the spinal cord parenchyma known as a syrinx. Although there is a significant volume of studies analysing the underlying mechanisms behind their formation, the management of such cavities remains an ongoing topic of debate. Aside from conservative approach, a range of surgical options exist, however long term outcomes are poor and a literature search reveals that the overall benefits are questionable...
July 13, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28712734/combined-direct-and-indirect-traumatic-carotid-cavernous-fistula-ccf-case-report-and-review-of-the-literature
#17
Isaac Josh Abecassis, Ryan P Morton, Louis J Kim, Basavaraj V Ghodke, Michael R Levitt
BACKGROUND: Within the current Barrow classification system, there are no categorical descriptions or reports in the literature of cavernous carotid fistulas (CCFs) with both a direct component (type A) and separate indirect contribution (type B, C, or D). We report the first definitive case of a combined simultaneous traumatic direct and indirect CCF, and review the literature on the similar existing entity of traumatic indirect CCFs presenting delayed and subsequent to the treatment of traumatic, direct CCFs...
July 13, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28709694/early-clinical-manifestations-of-s%C3%A3-zary-syndrome-a-multicenter-retrospective-cohort-study
#18
Aaron R Mangold, Agnieszka K Thompson, Mark D Davis, Ieva Saulite, Antonio Cozzio, Emmanuella Guenova, Emmilia Hodak, Iris Amitay-Laish, Ramon M Pujol, Mark R Pittelkow, Robert Gniadecki
BACKGROUND: Classic Sézary syndrome (SS) is defined by erythroderma, generalized lymphadenopathy, and leukemic blood involvement. Clinical observations suggest that SS begins as a nonerythrodermic disease. OBJECTIVE: To describe the early clinical characteristics of patients with SS. METHODS: A retrospective, multicenter chart review was performed for 263 confirmed cases of SS diagnosed during 1976-2015. RESULTS: Erythroderma was the earliest recorded skin sign of SS in only 25...
July 11, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28708988/early-colonisation-of-urban-indoor-carcasses-by-blow-flies-diptera-calliphoridae-an-experimental-study-from-central-spain
#19
Daniel Martín-Vega, Carla Martín Nieto, Blanca Cifrián, Arturo Baz, Luisa M Díaz-Aranda
Due to their ubiquity and synanthropy, blow flies (Diptera: Calliphoridae) are generally the first colonisers of cadavers and, therefore, frequently used to estimate a minimum post-mortem interval (minPMI). Whereas in outdoor situations blow flies are expected to locate and colonise exposed cadavers within hours or even minutes after death, it is usually assumed that the colonisation of a cadaver indoors might be delayed for an uncertain period of time. This uncertainty severely limits the informativity of minPMI estimates based on entomological evidence...
July 8, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28706619/kawasaki-disease-presenting-with-bloody-diarrhea-and-acute-renal-failure-first-case
#20
Mary Jacqueline Saviour, Sam Hassan
Kawasaki disease (KD) is an acute febrile vasculitis of an unknown cause. It affects children <5 year of age, even if cases over 5 years old have been also reported. It is the commonest cause of acquired heart diseases in children which may lead to serious morbidity and mortality. The complications and mortality increase when the diagnosis is delayed. One of the main reasons leading to delayed diagnosis and consequent delayed treatment is the unusual presentation of KD. Its unusual manifestations have been increasingly reported to jeopardize the timely diagnosis and proper treatment...
June 26, 2017: Pediatric Reports
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