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https://www.readbyqxmd.com/read/28437380/lifestyle-and-neurocognition-in-older-adults-with-cardiovascular-risk-factors-and-cognitive-impairment
#1
James A Blumenthal, Patrick J Smith, Stephanie Mabe, Alan Hinderliter, Kathleen Welsh-Bohmer, Jeffrey N Browndyke, Pao-Hwa Lin, William Kraus, P Murali Doraiswamy, James Burke, Andrew Sherwood
OBJECTIVE: To determine the relationship of lifestyle factors and neurocognitive functioning in older adults with vascular risk factors and cognitive impairment, without dementia (CIND). METHODS: One hundred sixty adults (Mean = 65.4±6.8 years) with CIND completed neurocognitive assessments of executive function, processing speed, and memory. Objective measures of physical activity using accelerometry, aerobic capacity determined by exercise testing, and dietary habits quantified by the Food Frequency Questionnaire and 4-Day Food Diary to assess adherence to the Mediterranean and DASH diets were obtained to assess direct effects with neurocognition...
April 21, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28436526/structural-implications-on-the-excitation-dynamics-of-fluorescent-3h-indolium-cations
#2
Ek Raj Thapaliya, Jaume Garcia-Amorós, Santi Nonell, Burjor Captain, Françisco M Raymo
Fluorescent 3H-indolium cations are valuable components for the realization of activatable fluorophores for bioimaging applications. Their relatively poor fluorescent quantum yields in organic solvents, however, appear to be in contradiction to their good performance in analytical methods based on single-molecule detection. The elucidation of the structural factors governing the excitation dynamics of these compounds is, therefore, essential to rationalize these effects and possibly guide the future design of activatable probes with improved performance...
April 24, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28435555/the-radial-bow-following-square-nailing-in-radius-and-ulna-shaft-fractures-in-adults-and-its-relation-to-disability-and-function
#3
M B Dave, K D Parmar, B A Sachde
One of the points made against nailing in radius and ulna shaft fractures has been the loss of radial bow and its impact on function. The aims of the study were to assess the change in magnitude and location of the radial bow in radius and ulna shaft fractures treated with intramedullary square nails and to assess the impact of this change on functional outcome, patient reported disability and the range of motion of the forearm. We measured the magnitude of radial bow and its location in the operated extremity and compared it to the uninjured side in 32 adult patients treated with intramedullary square nailing for radius and ulna shaft fractures at our institute...
July 2016: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435335/what-is-the-effect-of-a-shoulder-strengthening-program-to-prevent-shoulder-pain-among-junior-female-team-handball-players
#4
Maria Sommervold, Håvard Østerås
BACKGROUND: Excessively high stresses are applied to the shoulder joint of handball players, mainly caused by overhead throwing. Shoulder pain is a significant problem among junior female team handball players and both male and female top-level team handball players in Norway. METHOD: A randomized selection was performed among the best female junior teams (J 16) in the Trøndelag region of Norway in the 2014-2015 season. Three teams were randomized to the intervention group and three teams to the control group...
2017: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/28433682/a-mechanistic-review-on-vermifiltration-of-wastewater-design-operation-and-performance
#5
REVIEW
Rajneesh Singh, Puspendu Bhunia, Rajesh R Dash
With global population explosion, the available water resources are slowly being polluted due to the excessive human interference. To encounter this, it is the need of this hour to find out sustainable pollution remediating technologies to meet the stringent discharge standards for domestic as well as industrial wastewaters. In addition, those techniques should have the capabilities for effective implementation even in developing countries. Based on the available literatures, one such technique, named vermifilter, has been identified which takes care of almost all the sustainable and economical criteria for its effective implementation even in developing countries...
April 19, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28431899/validation-of-the-fact-b-4-ul-questionnaire-and-exploration-of-its-predictive-value-in-women-submitted-to-surgery-for-breast-cancer
#6
Juan Alfonso Andrade Ortega, Ana Pilar Millán Gómez, Marisa Ribeiro González, Pilar Martínez Piró, Juan Jiménez Anula, María Belén Sánchez Andújar
INTRODUCTION AND OBJETIVE: The early detection of upper limb complications is important in women operated on for breast cancer. The "FACT-B+4-UL" questionnaire, a specific variant of the Functional Assessment of Cancer Therapy-Breast (FACT-B) is available among others to measure the upper limb function. PATIENTS AND METHODS: The Spanish version of the upper limb subscale of the FACT-B+4 was validated in a prospective cohort of 201 women operated on for breast cancer (factor analysis, internal consistency, test-retest reliability, construct validity and sensitivity to change were determined)...
April 18, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28430721/outcomes-of-reverse-total-shoulder-arthroplasty-for-proximal-humeral-fractures-primary-arthroplasty-versus-secondary-arthroplasty-following-failed-proximal-humeral-locking-plate-fixation
#7
Emilio Sebastia-Forcada, Alejandro Lizaur-Utrilla, Román Cebrian-Gomez, Francisco A Miralles-Muñoz, Fernando A Lopez-Prats
OBJECTIVE: To compare the outcomes of reverse shoulder arthroplasty (RSA) between patients with failed proximal humeral locking plate (PHLP) fixation and those with acute fractures. DESIGN: Matched case-control study. SETTING: University hospital, level I trauma center. PATIENTS: 30 consecutive patients with fracture sequelae due to failed PHLP fixation (mean age 73) were age- and gender-matched to 30 patients with acute fracture (mean age 75)...
April 6, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28430281/insertion-of-sodium-phosphaethynolate-na-ocp-into-a-zirconium-benzyne-complex
#8
Jerod M Kieser, Robert J Gilliard, Arnold L Rheingold, Hansjörg Grützmacher, John D Protasiewicz
Reaction of the zirconium-benzyne complex [Cp2Zr(PMe3)(C6H4)] with sodium phosphaethynolate, Na[OCP], affords a zircono-phosphaalkene complex. Notably, unlike reactions of other transition metal complexes with Na[OCP] that yield the products of simple salt metathesis, this transformation represents novel Na[OCP] insertion chemistry and formation of an unusual solid state coordination polymer. The polymer is disrupted upon addition of Me3SiCl to afford a silyl-capped dimer that retains the zirconophosphaalkene functionality...
April 21, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28430223/data-processing-error-analysis-based-on-doppler-asymmetric-spatial-heterodyne-measurement
#9
Jing Shen, Wei Xiong, Hai-Liang Shi, Hai-Yan Luo, Zhi-Wei Li, Guang-Xiao Hu, Xue-Jing Fang
The Doppler asymmetric spatial heterodyne (DASH) interferometer provides the capability to retrieve wind speed in the upper atmosphere. The data processing leads to a significant retrieving error with the development of wind precision. The influence of window parameters on the isolated interferogram is analyzed theoretically. Based on the derivation, the system is established, and the interferogram with a small shift is sampled. The phase and wind speed are calculated under various window types and window width values...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28428914/development-and-validation-of-a-disease-specific-questionnaire-for-basal-joint-arthritis
#10
Peter C Noback, Joseph M Lombardi, Mani Seetharaman, Donald H Lee, Robert J Strauch, Melvin P Rosenwasser
Background The Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire is the most commonly used instrument to assess outcomes of basal joint arthritis (BJA). However, the DASH is subject to influence by the entire upper extremity. Purpose This study aims to develop and validate a disease-specific questionnaire for BJA that would be more sensitive to changes in thumb function and pain, and correlate better with objective and subjective metrics. Patients and Methods The thumb disability examination (TDX) was developed and 80 patients presenting with BJA at one of the two hospital-based hand clinics were enrolled in the validation study...
May 2017: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/28428775/genomics-reveals-a-unique-clone-of-burkholderia-cenocepacia-harboring-an-actively-excising-novel-genomic-island
#11
Prashant P Patil, Swapna Mali, Samriti Midha, Vikas Gautam, Lona Dash, Sunil Kumar, Jayanthi Shastri, Lipika Singhal, Prabhu B Patil
Burkholderia cenocepacia is a clinically dominant form among the other virulent species of Burkholderia cepacia complex (Bcc). In the present study, we sequenced and analyzed the genomes of seven nosocomial Bcc isolates, five of which were isolated from the bloodstream infections and two isolates were recovered from the hospital setting during the surveillance. Genome-based species identification of the Bcc isolates using a type strain explicitly identified the species as B. cenocepacia. Moreover, single nucleotide polymorphism analysis revealed that the six isolates were clonal and phylogenetically distinct from the other B...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28428037/conservative-treatment-of-displaced-distal-radius-fractures-leads-to-acceptable-functional-outcomes-however-at-the-expense-of-40-subsequent-surgeries
#12
Marjolein A M Mulders, Percy V van Eerten, J Carel Goslings, Niels W L Schep
BACKGROUND: Although secondary displacement following closed reduction and plaster immobilisation is high, several guidelines still recommend non-operative treatment for displaced distal radius fractures with an adequate closed reduction. PURPOSE: The purpose of this study was to evaluate functional outcomes, measured with the Disability of the Arm, Shoulder and Hand (DASH) questionnaire, in non-operative treated patients with displaced distal radius fractures with an adequate closed reduction confirmed on radiograph...
April 17, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28427870/all-endoscopic-brachial-plexus-complete-neurolysis-for-idiopathic-neurogenic-thoracic-outlet-syndrome-a-prospective-case-series
#13
Thibault Lafosse, Malo Le Hanneur, Laurent Lafosse
PURPOSE: To describe an all-endoscopic technique for infra- and supraclavicular brachial plexus (BP) neurolysis and to assess its functional outcomes for patients suffering from nonspecific neurogenic thoracic outlet syndrome (NTOS). METHODS: Between January 2010 and January 2013, 36 patients presenting an idiopathic nonspecific NTOS benefited from an endoscopic decompression in our institution. The inclusion criteria were a typical clinical NTOS and failure of a 6-month well-conducted nonsurgical treatment...
April 17, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28426076/an-amidato-divalent-ytterbium-cluster-synthesis-and-molecular-structure-its-reactivity-to-carbodiimides-and-application-in-the-guanylation-reaction
#14
Chao Gong, Hao Ding, Chengrong Lu, Bei Zhao, Yingming Yao
A divalent ytterbium amidate 1 ([Yb3L6]·2C7H8 for short) was synthesized via amine-elimination of Yb[N(SiMe3)2]2(TMEDA) with an amide proligand N-2,6-diisopropylphenylbenzamide HL (L = 2,6-(i)Pr2C6H3NC(O)Ph) and structurally characterized to be a trinuclear symmetric cluster. Further studies on the reduction of (i)PrN[double bond, length as m-dash]C[double bond, length as m-dash]N(i)Pr by complex 1 provide Yb(iii) complex 2 in hexane-THF ([(YbL2)2(μ-N(i)PrCN(i)Pr)][YbL3(THF)]·C7H8), which is composed of two subunits in a unit cell, one is a bridged Yb(iii) carbene, just the same as complex 4 ([(YbL2)2(μ-N(i)PrCN(i)Pr)]·3C7H8) obtained in the same reaction in toluene, and the other is a homoleptic monomeric Yb(iii) amidate (YbL3)...
April 20, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28425478/data-intensive-genome-level-analysis-for-identifying-novel-non-toxic-drug-targets-for-multi-drug-resistant-mycobacterium-tuberculosis
#15
Divneet Kaur, Rintu Kutum, Debasis Dash, Samir K Brahmachari
We report the construction of a novel Systems Biology based virtual drug discovery model for the prediction of non-toxic metabolic targets in Mycobacterium tuberculosis (Mtb). This is based on a data-intensive genome level analysis and the principle of conservation of the evolutionarily important genes. In the 1623 sequenced Mtb strains, 890 metabolic genes identified through a systems approach in Mtb were evaluated for non-synonymous mutations. The 33 genes showed none or one variation in the entire 1623 strains, including 1084 Russian MDR strains...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28424917/cubital-tunnel-syndrome-caused-by-ganglion-cysts-a-review-of-59-cases
#16
Jinsong Tong, Bin Xu, Zhen Dong, Jingbo Liu, Chenggang Zhang, Yudong Gu
BACKGROUND: Cubital tunnel syndrome caused by ganglion cysts is rare and reports are few. This study aimed to review a patient cohort with ganglion cysts in the cubital tunnel and identify prognostic factors. METHODS: Fifty-seven patients (59 extremities; McGowan grade I, 4; IIa, 4; IIb, 3; III, 48) were evaluated retrospectively with a minimum follow-up of 2 years. Extraneural cysts were excised completely, while intraneural cysts were incised and drained. All cases underwent subcutaneous transposition...
April 19, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28424256/dietary-patterns-and-type-2-diabetes-a-systematic-literature-review-and-meta-analysis-of-prospective-studies
#17
Franziska Jannasch, Janine Kröger, Matthias B Schulze
Background: Different methodologic approaches for constructing dietary patterns and differences in their composition limit conclusions on healthful patterns for diabetes prevention.Objective: We summarized evidence from prospective studies that examined associations of dietary patterns with type 2 diabetes by considering different methodologic approaches.Methods: The literature search (MEDLINE and Web of Science) identified prospective studies (cohorts or trials) that associated dietary patterns with diabetes incidence in nondiabetic and apparently healthy participants...
April 19, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28424183/biomarker-calibrated-nutrient-intake-and-healthy-diet-index-associations-with-mortality-risks-among-older-and-frail-women-from-the-women-s-health-initiative
#18
Oleg Zaslavsky, Shira Zelber-Sagi, James R Hebert, Susan E Steck, Nitin Shivappa, Fred K Tabung, Michael D Wirth, Yunqi Bu, James M Shikany, Tonya Orchard, Robert B Wallace, Linda Snetselaar, Lesley F Tinker
Background: Although studies to date have confirmed the association between nutrition and frailty, the impact of dietary intake and dietary patterns on survivorship in those with frailty is yet to be examined in a well-powered cohort with validated frailty status. Moreover, previous studies were limited by measurement error from dietary self-reports.Objective: We derived biomarker-calibrated dietary energy and protein intakes to address dietary self-report error. Using these data, we then evaluated the association of mortality in older women with frailty and dietary intake and healthy diet indexes, such as the alternate Mediterranean Diet (aMED), the Dietary Approaches to Stop Hypertension (DASH) score, and the Dietary Inflammatory Index (DII)...
April 19, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28422880/the-management-and-surgical-intervention-timing-of-enchondromas-a-10-year-experience
#19
Xijie Zhou, Bin Zhao, Poonit Keshav, Xinglong Chen, Weiyang Gao, Hede Yan
Enchondroma, reportedly the most common primary tumor of the long bones of the hand, usually develops during the first till fourth decades of life. However, there has no consensus been reached regarding the surgical intervention timing for these patients. We aim to evaluate the optimal surgical intervention timing for the patients with fractures due to enchondromas, investigate the impact of pathological fractures on the treatment and outcomes in these patients.Medical records and X-rays of patients treated for enchondroma of the hand from 2005 to 2015 were retrospectively reviewed...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28422248/umpolung-of-protons-from-h2o-a-metal-free-chemoselective-reduction-of-carbonyl-compounds-via-b2pin2-h2o-systems
#20
Qingqing Xuan, Cong Zhao, Qiuling Song
H2O is routinely described as a proton donor, however, in the presence of diboron compounds, the umpolung reaction of H2O under metal-free conditions was successfully developed, which could afford hydride species, leading to a highly efficient and chemoselective reduction of C[double bond, length as m-dash]O bonds. This strategy exhibits excellent chemoselectivities toward carbonyl groups in the presence of ester, olefin, halogen, thioether, sulfonyl, cyano as well as heteroaromatic groups.
April 19, 2017: Organic & Biomolecular Chemistry
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