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Developmental Neuroscience

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https://www.readbyqxmd.com/read/29215164/magnetically-guided-self-assembly-and-coding-of-3d-living-architectures
#1
Alessandro Tocchio, Naside Gozde Durmus, Kaushik Sridhar, Vigneshwaran Mani, Bukre Coskun, Rami El Assal, Utkan Demirci
In nature, cells self-assemble at the microscale into complex functional configurations. This mechanism is increasingly exploited to assemble biofidelic biological systems in vitro. However, precise coding of 3D multicellular living materials is challenging due to their architectural complexity and spatiotemporal heterogeneity. Therefore, there is an unmet need for an effective assembly method with deterministic control on the biomanufacturing of functional living systems, which can be used to model physiological and pathological behavior...
December 7, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29215142/cortical-thickness-resting-state-heart-rate-and-heart-rate-variability-in-female-adolescents
#2
Julian Koenig, Peter Parzer, Corinna Reichl, Ayaka Ando, Julian F Thayer, Romuald Brunner, Michael Kaess
Resting state heart rate variability (HRV) is a psychophysiological marker that has gained increasing research interest, in particular in developmental neuroscience. HRV has been shown to be associated with mental and physical health, beyond simple measures of heart rate (HR) and shows inter- and intraindividual variance across aging. Recently, three studies reported on a positive correlation between resting state HRV and cortical thickness in selected regions of interest (ROIs) in adult samples. Structural thickness, HRV, and HR change during the sensitive period of adolescence...
December 7, 2017: Psychophysiology
https://www.readbyqxmd.com/read/29196032/current-methods-and-limitations-for-longitudinal-fmri-analysis-across-development
#3
Tara Madhyastha, Matthew Peverill, Natalie Koh, Connor McCabe, John Flournoy, Kate Mills, Kevin King, Jennifer Pfeifer, Katie A McLaughlin
The human brain is remarkably plastic. The brain changes dramatically across development, with ongoing functional development continuing well into the third decade of life and substantial changes occurring again in older age. Dynamic changes in brain function are thought to underlie the innumerable changes in cognition, emotion, and behavior that occur across development. The brain also changes in response to experience, which raises important questions about how the environment influences the developing brain...
November 22, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29177462/cohort-profile-the-nspn-2400-cohort-a-developmental-sample-supporting-the-wellcome-trust-neuroscience-in-psychiatry-network
#4
Beatrix Kiddle, Becky Inkster, Gita Prabhu, Michael Moutoussis, Kirstie J Whitaker, Edward T Bullmore, Raymond J Dolan, Peter Fonagy, Ian M Goodyer, Peter B Jones
No abstract text is available yet for this article.
November 21, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29163318/anger-as-a-basic-emotion-and-its-role-in-personality-building-and-pathological-growth-the-neuroscientific-developmental-and-clinical-perspectives
#5
Riccardo Williams
Anger is probably one of the mostly debated basic emotions, owing to difficulties in detecting its appearance during development, its functional and affective meaning (is it a positive or a negative emotion?), especially in human beings. Behaviors accompanied by anger and rage serve many different purposes and the nuances of aggressive behaviors are often defined by the symbolic and cultural framework and social contexts. Nonetheless, recent advances in neuroscientific and developmental research, as well as clinical psychodynamic investigation, afford a new view on the role of anger in informing and guiding many aspects of human conducts...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29162696/expansion-microscopy-of-zebrafish-for-neuroscience-and-developmental-biology-studies
#6
Limor Freifeld, Iris Odstrcil, Dominique Förster, Alyson Ramirez, James A Gagnon, Owen Randlett, Emma K Costa, Shoh Asano, Orhan T Celiker, Ruixuan Gao, Daniel A Martin-Alarcon, Paul Reginato, Cortni Dick, Linlin Chen, David Schoppik, Florian Engert, Herwig Baier, Edward S Boyden
Expansion microscopy (ExM) allows scalable imaging of preserved 3D biological specimens with nanoscale resolution on fast diffraction-limited microscopes. Here, we explore the utility of ExM in the larval and embryonic zebrafish, an important model organism for the study of neuroscience and development. Regarding neuroscience, we found that ExM enabled the tracing of fine processes of radial glia, which are not resolvable with diffraction-limited microscopy. ExM further resolved putative synaptic connections, as well as molecular differences between densely packed synapses...
November 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29158160/glycoprotein-m6a-as-a-signaling-transducer-in-neuronal-lipid-rafts
#7
Yasuyuki Ito, Atsuko Honda, Michihiro Igarashi
Neuronal development is composed of the complex steps which involve many signaling proteins. On the other hand, there are many proteins highly expressed in the differentiated neurons at developmental stages, but of which physiological functions are not precisely known so far. Glycoprotein 6a (GPM6a) currently belongs to such proteins. This protein has four-transmembrane domains and is a member of proteolipid protein family. Recently, we demonstrated that GPM6a is highly concentrated in lipid rafts of the developing neuron with its palmitoylation, and that this molecule is involved in rapid determination of the neuronal polarity, in response to laminin, an extracellular matrix protein (Honda et al...
November 17, 2017: Neuroscience Research
https://www.readbyqxmd.com/read/29158072/test-retest-reliability-of-longitudinal-task-based-fmri-implications-for-developmental-studies
#8
REVIEW
Megan M Herting, Prapti Gautam, Zhanghua Chen, Adam Mezher, Nora C Vetter
Great advances have been made in functional Magnetic Resonance Imaging (fMRI) studies, including the use of longitudinal design to more accurately identify changes in brain development across childhood and adolescence. While longitudinal fMRI studies are necessary for our understanding of typical and atypical patterns of brain development, the variability observed in fMRI blood-oxygen-level dependent (BOLD) signal and its test-retest reliability in developing populations remain a concern. Here we review the current state of test-retest reliability for child and adolescent fMRI studies (ages 5-18 years) as indexed by intraclass correlation coefficients (ICC)...
July 13, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29151590/microglia-and-macrophages-in-brain-homeostasis-and-disease
#9
REVIEW
Qingyun Li, Ben A Barres
Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology...
November 20, 2017: Nature Reviews. Immunology
https://www.readbyqxmd.com/read/29125518/a-trauma-informed-approach-supports-health-and-development-in-children-and-youth-with-spina-bifida
#10
Veronica Meneses, Natalie Cruz
Children with developmental disabilities may be at greater risk for experiencing maltreatment and traumatic events, threats to their physical and psychological safety and well-being. Young children and youth with spina bifida benefit from being considered in light of this risk, and may be especially vulnerable given the complexity of their neurodevelopmental condition. A trauma-informed approach brings together evidence from the neurosciences, epidemiology and psychology to promote improved developmental, behavioral, physical and mental health status...
October 20, 2017: Journal of Pediatric Rehabilitation Medicine
https://www.readbyqxmd.com/read/29110344/current-technical-approaches-to-brain-energy-metabolism
#11
REVIEW
L Felipe Barros, Juan P Bolaños, Gilles Bonvento, Anne-Karine Bouzier-Sore, Angus Brown, Johannes Hirrlinger, Sergey Kasparov, Frank Kirchhoff, Anne N Murphy, Luc Pellerin, Michael B Robinson, Bruno Weber
Neuroscience is a technology-driven discipline and brain energy metabolism is no exception. Once satisfied with mapping metabolic pathways at organ level, we are now looking to learn what it is exactly that metabolic enzymes and transporters do and when, where do they reside, how are they regulated, and how do they relate to the specific functions of neurons, glial cells, and their subcellular domains and organelles, in different areas of the brain. Moreover, we aim to quantify the fluxes of metabolites within and between cells...
November 7, 2017: Glia
https://www.readbyqxmd.com/read/29107609/the-utility-of-twins-in-developmental-cognitive-neuroscience-research-how-twins-strengthen-the-abcd-research-design
#12
REVIEW
William G Iacono, Andrew C Heath, John K Hewitt, Michael C Neale, Marie T Banich, Monica M Luciana, Pamela A Madden, Deanna M Barch, James M Bjork
The ABCD twin study will elucidate the genetic and environmental contributions to a wide range of mental and physical health outcomes in children, including substance use, brain and behavioral development, and their interrelationship. Comparisons within and between monozygotic and dizygotic twin pairs, further powered by multiple assessments, provide information about genetic and environmental contributions to developmental associations, and enable stronger tests of causal hypotheses, than do comparisons involving unrelated children...
September 12, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29101644/personalizing-and-optimizing-preventive-intervention-models-via-a-translational-neuroscience-framework
#13
Diana H Fishbein, Jacinda K Dariotis
A new generation of research, building upon developmental psychopathology (Luthar et al. 1997; Luthar et al. (Child Development, 71, 543-562, 2000)), provides evidence that individual differences in risk for behavioral health problems result from intrapersonal and environmental modulation of neurophysiologic and genetic substrates. This transdisciplinary model suggests that, in any given individual, the number of genetic variants implicated in high-risk behavior and the way in which they are assorted and ultimately suppressed or activated in the brain by experiential and contextual factors help to explain behavioral orientations...
November 3, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29101011/fast-furious-and-enduring-sensitive-versus-critical-periods-in-sexual-differentiation-of-the-brain
#14
Margaret M McCarthy, Kevin Herold, Sara L Stockman
Understanding critical periods in brain development and how they impact adult functioning is a primary goal of neuroscience. The sexual differentiation of the brain is a unique critical period in that it is initiated by endogenous production of a critical signaling molecule in only one sex, testosterone in fetal males. Females, by contrast, do not produce testosterone but are highly responsive to it and remain sensitive to its masculinizing effects well past the close of the critical period in males. Compared to other well characterized critical periods, such as those for the visual system or barrel cortex, the masculinization of the brain is telescoped into a few short days and initiated prenatally...
October 31, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/29064008/paediatric-population-neuroimaging-and-the-generation-r-study-the-second-wave
#15
Tonya White, Ryan L Muetzel, Hanan El Marroun, Laura M E Blanken, Philip Jansen, Koen Bolhuis, Desana Kocevska, Sabine E Mous, Rosa Mulder, Vincent W V Jaddoe, Aad van der Lugt, Frank C Verhulst, Henning Tiemeier
Paediatric population neuroimaging is an emerging field that falls at the intersection between developmental neuroscience and epidemiology. A key feature of population neuroimaging studies involves large-scale recruitment that is representative of the general population. One successful approach for population neuroimaging is to embed neuroimaging studies within large epidemiological cohorts. The Generation R Study is a large, prospective population-based birth-cohort in which nearly 10,000 pregnant mothers were recruited between 2002 and 2006 with repeated measurements in the children and their parents over time...
October 24, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29053770/tourette-syndrome-a-disorder-of-the-social-decision-making-network
#16
Roger L Albin
Tourette syndrome is a common neurodevelopmental disorder defined by characteristic involuntary movements, tics, with both motor and phonic components. Tourette syndrome is usually conceptualized as a basal ganglia disorder, with an emphasis on striatal dysfunction. While considerable evidence is consistent with these concepts, imaging data suggest diffuse functional and structural abnormalities in Tourette syndrome brain. Tourette syndrome exhibits features that are difficult to explain solely based on basal ganglia circuit dysfunctions...
August 22, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29033780/evolutionary-musicology-meets-embodied-cognition-biocultural-coevolution-and-the-enactive-origins-of-human-musicality
#17
REVIEW
Dylan van der Schyff, Andrea Schiavio
Despite evolutionary musicology's interdisciplinary nature, and the diverse methods it employs, the field has nevertheless tended to divide into two main positions. Some argue that music should be understood as a naturally selected adaptation, while others claim that music is a product of culture with little or no relevance for the survival of the species. We review these arguments, suggesting that while interesting and well-reasoned positions have been offered on both sides of the debate, the nature-or-culture (or adaptation vs...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29016175/missing-developmental-and-sociocultural-perspectives-comment-on-the-psychology-of-terrorism-special-issue-2017
#18
Cynthia García Coll, Amy K Marks
Two critical perspectives were missing from the special issue entitled "Psychology of Terrorism": developmental and sociocultural. From a developmental point of view, the fact that most individuals who engage in terrorist groups or terroristic acts are young men is critically important. Perspectives from adolescent development, neuroscience, and social psychology can shed light on why this is the case. In addition, sociocultural perspectives are needed to answer important community-level questions, such as why some communities are more prone to having youth recruited for terrorism than others...
October 2017: American Psychologist
https://www.readbyqxmd.com/read/28994010/parsing-the-neural-correlates-of-anxious-apprehension-and-anxious-arousal-in-the-grey-matter-of-healthy-youth
#19
Peter J Castagna, Scott Roye, Matthew Calamia, Joshua Owens-French, Thompson E Davis, Steven G Greening
Neuroscientific and psychological research posits that there are two transdiagnostic facets of anxiety: anxious arousal and anxious apprehension. Though these two facets of anxiety are distinct, they are often subsumed into one domain (e.g., trait anxiety). The primary goal of the current study was to delineate the relationship between anxious arousal and cortical thickness versus the relationship between anxious apprehension and cortical thickness in a sample of typically functioning youth. The secondary aim was to determine where in the brain cortical thickness significantly correlated with both components of anxiety...
October 9, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28975039/creative-music-therapy-to-promote-brain-structure-function-and-neurobehavioral-outcomes-in-preterm-infants-a-randomized-controlled-pilot-trial-protocol
#20
Friederike Barbara Haslbeck, Hans-Ulrich Bucher, Dirk Bassler, Cornelia Hagmann
BACKGROUND: Preterm birth is associated with increased risk of neurological impairment and deficits in cognition, motor function, and behavioral problems. Limited studies indicate that multi-sensory experiences support brain development in preterm infants. Music appears to promote neurobiological processes and neuronal learning in the human brain. Creative music therapy (CMT) is an individualized, interactive therapeutic approach based on the theory and methods of Nordoff and Robbins...
2017: Pilot and Feasibility Studies
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