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https://www.readbyqxmd.com/read/28535423/chromatographic-separation-and-detection-methods-of-aloe-arborescens-miller-constituents-a-systematic-review
#1
REVIEW
Jilan A Nazeam, Haidy A Gad, Hala M El-Hefnawy, Abdel-Naser B Singab
Aloe arborescens Miller (Family Asphodelaceae) is a member of genus Aloe, which is used in traditional medicine to cure various diseases. The extracts of the plant have been reported to possess anticancer, immunomodulator, antidiabetic, anti-inflammatory and antioxidant activities. The phytochemical investigations have revealed diverse chemical constituents, including phenolics [anthraquinones, anthrones, pyrones, chromones and coumarins], polysaccharides [arborans [(1-4) linked glucomannans, polysaccharide (A, B and C): (A: a linear (1-6)-O-α-glucan, B: a branching (1-2)-O-l-arabinose with (1-2)-O-d-galactose linkages and C: (1-4)-O-β-mannan with 18% acetyl group)]], glycoproteins and carboxypeptidase enzyme...
April 29, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28535379/image-and-message-recruiting-the-right-nurses-for-the-profession-a-qualitative-study
#2
Anthony Tuckett, Hyein Kim, Jihye Huh
AIM: The aim of this study was to identify the key word(s) or phrases; and key image(s) new to nursing professionals would recommend using in a recruitment poster to encourage school leavers to study nursing or midwifery. BACKGROUND: An updated imaging and messaging in the profession is needed in recruitment initiatives targeting high school students to perceive registered nursing as a lifelong career. METHOD: Open-ended responses reported through the Graduate e-Cohort Study (GeS) Survey 7 2015, representing 109 nursing and midwifery graduates from Australia and New Zealand...
May 17, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28535264/the-impact-of-the-physical-environment-on-depressive-symptoms-of-older-residents-living-in-care-homes-a-mixed-methods-study
#3
Rachel Potter, Bart Sheehan, Rebecca Cain, James Griffin, Paul A Jennings
Background and Objectives: Forty percent of residents living in care homes in the United Kingdom have significant depressive symptoms. Care homes can appear to be depressing places, but whether the physical environment of homes directly affects depression in care home residents is unknown. This study explores the relationship between the physical environment and depressive symptoms of older people living in care homes. Research Design and Methods: In a prospective cohort study the physical environment of 50 care homes were measured using the Sheffield Care Environment Assessment Matrix (SCEAM) and depressive symptoms of 510 residents measured using the Geriatric Depression Scale (GDS-15)...
May 23, 2017: Gerontologist
https://www.readbyqxmd.com/read/28535261/recruitment-of-a-lineage-specific-virulence-regulatory-pathway-promotes-intracellular-infection-by-a-plant-pathogen-experimentally-evolved-into-a-legume-symbiont
#4
Delphine Capela, Marta Marchetti, Camille Clérissi, Anthony Perrier, Dorian Guetta, Carine Gris, Marc Valls, Alain Jauneau, Stéphane Cruveiller, Eduardo P C Rocha, Catherine Masson-Boivin
Ecological transitions between different lifestyles, such as pathogenicity, mutualism and saprophytism, have been very frequent in the course of microbial evolution, and often driven by horizontal gene transfer. Yet, how genomes achieve the ecological transition initiated by the transfer of complex biological traits remains poorly known. Here we used experimental evolution, genomics, transcriptomics and high-resolution phenotyping to analyze the evolution of the plant pathogen Ralstonia solanacearum into legume symbionts, following the transfer of a natural plasmid encoding the essential mutualistic genes...
May 23, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28535143/intercultural-communication-through-the-eyes-of-patients-experiences-and-preferences
#5
Emma Paternotte, Sandra van Dulmen, Lindsay Bank, Conny Seeleman, Albert Scherpbier, Fedde Scheele
Objectives: To explore patients' preferences and experiences regarding intercultural communication which could influence the development of intercultural patient-centred communication training. Methods: This qualitative study is based on interviews with non-native patients. Thirty non-native patients were interviewed between September and December 2015 about their preferences and experiences regarding communication with a native Dutch doctor. Fourteen interviews were established with an interpreter...
May 16, 2017: International Journal of Medical Education
https://www.readbyqxmd.com/read/28534854/methodical-challenges-and-a-possible-resolution-in-the-assessment-of-receptor-reserve-for-adenosine-an-agonist-with-short-half-life
#6
Judit Zsuga, Tamas Erdei, Katalin Szabó, Nora Lampe, Csaba Papp, Akos Pinter, Andras Jozsef Szentmiklosi, Bela Juhasz, Zoltán Szilvássy, Rudolf Gesztelyi
The term receptor reserve, first introduced and used in the traditional receptor theory, is an integrative measure of response-inducing ability of the interaction between an agonist and a receptor system (consisting of a receptor and its downstream signaling). The underlying phenomenon, i.e., stimulation of a submaximal fraction of receptors can apparently elicit the maximal effect (in certain cases), provides an opportunity to assess the receptor reserve. However, determining receptor reserve is challenging for agonists with short half-lives, such as adenosine...
May 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28534723/evaluation-of-a-jugular-venipuncture-alpaca-model-to-teach-the-technique-of-blood-sampling-in-adult-alpacas
#7
Marjolaine Rousseau, Guy Beauchamp, Sylvain Nichols
The effectiveness of teaching aids in veterinary medical education is not often assessed rigorously. The objective in the present study was to evaluate the effectiveness of a commercially available jugular venipuncture alpaca model as a complementary tool to teach veterinary students how to perform venipuncture in adult alpacas. We hypothesized that practicing on the model would allow veterinary students to draw blood in alpacas more rapidly with fewer attempts than students without previous practice on the model...
May 23, 2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28534672/a-review-of-the-principles-and-applications-of-near-infrared-spectroscopy-to-characterize-meat-fat-and-meat-products
#8
Nuria Prieto, Olga Pawluczyk, Michael Edward Russell Dugan, Jennifer Lynn Aalhus
Consumer demand for quality and healthfulness has led to a higher need for quality assurance in meat production. This requirement has increased interest in near-infrared (NIR) spectroscopy due to the ability for rapid, environmentally friendly, and non-invasive prediction of meat quality or authentication of added-value meat products. This review includes the principles of NIR spectroscopy, pre-processing methods, and multivariate analyses used for quantitative and qualitative purposes in the meat sector. Recent advances in portable NIR spectrometers that enable new online applications in the meat industry are shown and their performance evaluated...
January 1, 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28534618/microsecond-timescale-proton-rotating-frame-relaxation-under-magic-angle-spinning
#9
Petra Rovó, Rasmus Linser
This paper deals with the theoretical foundation of proton magic-angle-spinning rotating-frame relaxation (R1ρ) and establishes the range of validity and accuracy of the presented approach to describe low-amplitude microsecond timescale motion in the solid state. Beside heteronuclear dipolar and chemical shift anisotropy interactions, a major source of relaxation for protons is the homonuclear dipolar interaction. For this latter relaxation process no general analytical equation has been published until now which would describe the R1ρ relaxation at any spinning-speed, spin-lock field, or tilt-angle...
May 23, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28534436/perceptions-of-sport-science-students-on-the-potential-applications-and-limitations-of-blended-learning-in-their-education-a-qualitative-study
#10
Justin W L Keogh, Lisa Gowthorp, Michelle McLean
This study sought to gain insight into blended learning-naive sports science students' understanding and perceptions of the potential benefits and limitations of blended (hybrid) learning, which has been defined as the thoughtful integration of face-to-face and online instructional approaches. Five focus groups, each comprising 3-4 students from either the undergraduate or postgraduate sports science programmes were conducted. The focus groups were facilitated by a researcher who was not involved in sports science...
May 23, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/28534311/scale-space-for-empty-catheter-segmentation-in-pci-fluoroscopic-images
#11
Ketan Bacchuwar, Jean Cousty, Régis Vaillant, Laurent Najman
PURPOSE: In this article, we present a method for empty guiding catheter segmentation in fluoroscopic X-ray images. The guiding catheter, being a commonly visible landmark, its segmentation is an important and a difficult brick for Percutaneous Coronary Intervention (PCI) procedure modeling. METHODS: In number of clinical situations, the catheter is empty and appears as a low contrasted structure with two parallel and partially disconnected edges. To segment it, we work on the level-set scale-space of image, the min tree, to extract curve blobs...
May 22, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28534116/myeloid-neoplasms-with-germ-line-runx1-mutation
#12
REVIEW
Yoshihiro Hayashi, Yuka Harada, Gang Huang, Hironori Harada
Familial platelet disorder with propensity to myeloid malignancies (FPD/AML) is an autosomal dominant disorder characterized by quantitative and/or qualitative platelet defects with a tendency to develop a variety of hematological malignancies. Heterozygous germ line mutations in the RUNX1 gene are responsible genetic events for FPD/AML. Notably, about half of individuals in the family with germ line mutations in RUNX1 develop overt hematological malignancies. The latency is also relatively long as an average age at diagnosis is more than 30 years...
May 22, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/28533825/in-situ-mems-testing-correlation-of-high-resolution-x-ray-diffraction-with-mechanical-experiments-and-finite-element-analysis
#13
REVIEW
Andreas Schifferle, Alex Dommann, Antonia Neels
New methods are needed in microsystems technology for evaluating microelectromechanical systems (MEMS) because of their reduced size. The assessment and characterization of mechanical and structural relations of MEMS are essential to assure the long-term functioning of devices, and have a significant impact on design and fabrication. Within this study a concept for the investigation of mechanically loaded MEMS materials on an atomic level is introduced, combining high-resolution X-ray diffraction (HRXRD) measurements with finite element analysis (FEA) and mechanical testing...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28533667/octogenarian-liver-grafts-is-their-use-for-transplant-currently-justified
#14
Carlos Jiménez-Romero, Felix Cambra, Oscar Caso, Alejandro Manrique, Jorge Calvo, Alejandro Marcacuzco, Paula Rioja, David Lora, Iago Justo
AIM: To analyse the impact of octogenarian donors in liver transplantation. METHODS: We present a retrospective single-center study, performed between November 1996 and March 2015, that comprises a sample of 153 liver transplants. Recipients were divided into two groups according to liver donor age: recipients of donors ≤ 65 years (group A; n = 102), and recipients of donors ≥ 80 years (group B; n = 51). A comparative analysis between the groups was performed...
May 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28533530/the-impact-of-hand-foot-and-mouth-disease-control-policies-in-singapore-a-qualitative-analysis-of-public-perceptions
#15
Karen Siegel, Alex R Cook, Hanh La
Hand foot and mouth disease (HFMD) is a widespread pediatric disease in Asia. Most cases are relatively mild and caused by Coxsackie viruses, but in epidemics caused by Enterovirus 71, severe complications can occur. In response to the deaths of dozens of children in a 1997 outbreak (Podin in BMC Public Health 6:180,1 Abubakar in Virus Res 61(1):1-9,2 WHO in3), Singapore practices childcare centre surveillance, case-isolation, and short-term closure of centres. We conducted 44 in-depth interviews with teachers, principals, and parents at four childcare centres in Singapore to better understand experiences with current control policies...
May 2017: Journal of Public Health Policy
https://www.readbyqxmd.com/read/28533216/a-diverse-community-to-study-communities-integration-of-experiments-and-mathematical-models-to-study-microbial-consortia
#16
Antonella Succurro, Fiona Wanjiku Moejes, Oliver Ebenhöh
The last few years have seen the advancement of high-throughput experimental techniques produce an extraordinary amount of data. Bioinformatics and statistical analyses have become instrumental to interpreting the information coming from e.g. sequencing data, and often motivate further targeted experiments. The broad discipline of "computational biology" spans far beyond the well-established field of bioinformatics, but it is our impression that more theoretical methods like mathematical models are not yet as well integrated in the research studying microbial interactions...
May 22, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28533200/beliefs-about-prescribed-medication-among-older-patients-with-polypharmacy-a-mixed-methods-study-in-primary-care
#17
Barbara Clyne, Janine A Cooper, Fiona Boland, Carmel M Hughes, Tom Fahey, Susan M Smith
BACKGROUND: Polypharmacy (≥5 medications) is common in older patients and is associated with adverse outcomes. Patients' beliefs about medication can influence their expectations for medication, adherence, and willingness to deprescribe. Few studies have examined beliefs about prescribed medication among older patients with polypharmacy in primary care. AIM: To explore medication-related beliefs in older patients with polypharmacy and factors that might influence beliefs...
May 22, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28533198/chlamydia-and-hiv-testing-contraception-advice-and-free-condoms-offered-in-general-practice-a-qualitative-interview-study-of-young-adults-perceptions-of-this-initiative
#18
Leah Ffion Jones, Ellie Ricketts, Katy Town, Claire Rugman, Donna Lecky, Kate Folkard, Anthony Nardone, Thomas Nathan Hartney, Cliodna McNulty
BACKGROUND: Opportunistic chlamydia screening is actively encouraged in English general practices. Based on recent policy changes, Public Health England piloted 3Cs and HIV in 2013-2014, integrating the offer of chlamydia testing with providing condoms, contraceptive information, and HIV testing (referred to as 3Cs and HIV) according to national guidelines. AIM: To determine young adults' opinions of receiving a broader sexual health offer of 3Cs and HIV at their GP practice...
May 22, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28533112/where-arithmetic-and-phonology-meet-the-meta-analytic-convergence-of-arithmetic-and-phonological-processing-in-the-brain
#19
Courtney Pollack, Nicole C Ashby
Arithmetic facts can be solved using different strategies. Research suggests that some arithmetic problems, particularly those solved by fact retrieval, are related to phonological processing ability and elicit activity in left-lateralized brain regions that support phonological processing. However, it is unclear whether common brain regions support both retrieval-based arithmetic and phonological processing, and if these regions differ across children and adults. This study used activation likelihood estimation to investigate functional neural overlap between arithmetic and phonological processing, separately for children and adults...
May 10, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28533078/simulation-of-carotid-artery-stenting-reduces-training-procedure-and-fluoroscopy-times
#20
Andre F Gosling, Daniel E Kendrick, Ann H Kim, Anil Nagavalli, Ethan S Kimball, Nathaniel T Liu, Vikram S Kashyap, John C Wang
OBJECTIVE: Outcomes from carotid artery stenting (CAS) are related to experience and technical expertise of the operator. Simulation of CAS may enhance clinical proficiency. We interrogated the impact of endovascular simulation of CAS procedures in operators who are at various stages of training. METHODS: Twelve trainees (students [n = 4]; junior surgery residents, postgraduate year [PGY] 1-3 [n = 4]; and senior surgery residents or fellows, PGY 4-7 [n = 4]) were apprised of characteristics of an endovascular simulator and CAS procedures...
May 19, 2017: Journal of Vascular Surgery
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