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Chaoxian Chi, Jia-Qi Wang, Hui Qu, Wan-Lu Li, Luyan Meng, Mingbiao Luo, Jun Li, Mingfei Zhou
We report the preparation of UFe(CO)3(-) and OUFe(CO)3(-) complexes using a laser-vaporization supersonic ion source in the gas phase. These compounds were mass-selected and characterized by infrared photodissociation spectroscopy and state-of-the-art quantum chemical studies. There are unprecedented triple bonds between U 6d/5f and Fe 3d orbitals, featuring one covalent σ bond and two Fe-to-U dative π bonds in both complexes. The uranium and iron elements are found to exist in unique formal U(I or III) and Fe(-II) oxidation states, respectively...
May 9, 2017: Angewandte Chemie
Ryan Kohlbrenner, K Pallav Kolli, Andrew G Taylor, Maureen P Kohi, Evan D Lehrman, Nicholas Fidelman, Miles Conrad, Jeanne M LaBerge, Robert K Kerlan, Robert Gould
PURPOSE: To assess radiation dose reduction during uterine fibroid embolization (UFE) using an optimized angiographic processing and acquisition platform. MATERIALS AND METHODS: Radiation dose data for 70 women (mean age, 46 y; range, 34-67 y) who underwent UFE were retrospectively analyzed. Twenty-one patients underwent UFE using the baseline fluoroscopic and angiographic image acquisition platform, and 49 underwent UFE after implementing an optimized imaging platform in otherwise identical angiography suites...
April 27, 2017: Journal of Vascular and Interventional Radiology: JVIR
Hélène Vernhet Kovacsik, Denis Herbreteau, Sébastien Bommart, Jean-Paul Beregi, Jean-Michel Bartoli, Marc Sapoval
OBJECTIVES: The main goal of the study was to evaluate sexual function before and one year after UFE. The secondary goals were to evaluate the quality of life before and one year after UFE and to determine the relation of imaging findings (MRI data) before and 3-6 months after UFE to changes in sexual function and quality of life. MATERIALS AND METHODS: Study design: a prospective, multicenter (25 centers) observational study was conducted. PATIENTS: a total of 264 consecutive symptomatic women undergoing UFE using Embozene® (Celonova) from March 2012 to May 2013 were enrolled...
March 20, 2017: Cardiovascular and Interventional Radiology
Seung Hun Kang, Shin Jae Lee, Gyeong Sik Jeon, Sang-Wook Yoon
PURPOSE: To determine feasibility of scaled signal intensity (SSI) of uterine fibroids on T2-weighted magnetic resonance (MR) images to predict volume reduction rate (VRR) after uterine fibroid embolization (UFE). MATERIALS AND METHODS: In this retrospective study, 66 premenopausal women underwent UFE. Patients underwent follow-up MR imaging 3 months after UFE. SSI of predominant fibroids was measured on T2-weighted MR images obtained before the procedure by standardizing the mean signal intensity to a 0-to-100 scale, with 0 representing rectus abdominis muscle and 100 representing subcutaneous fat (100) for reference values...
March 10, 2017: Journal of Vascular and Interventional Radiology: JVIR
Rebecka Peebles, Andrew Lesser, Courtney Cheek Park, Kerri Heckert, C Alix Timko, Eleni Lantzouni, Ronald Liebman, Laurel Weaver
BACKGROUND: Medical stabilization through inpatient nutritional rehabilitation is often necessary for patients with eating disorders (EDs) but includes the inherent risk of refeeding syndrome. Here we describe our experience of implementing and sustaining an inpatient nutritional rehabilitation protocol designed to strategically prepare patients with EDs and their families for discharge to a home setting in an efficient and effective manner from a general adolescent medicine unit. We report outcomes at admission, discharge, and 4-weeks follow-up...
2017: Journal of Eating Disorders
Tolga Soykan, Natalie Kaempf, Takeshi Sakaba, Dennis Vollweiter, Felix Goerdeler, Dmytro Puchkov, Natalia L Kononenko, Volker Haucke
Neurotransmission is based on the exocytic fusion of synaptic vesicles (SVs) followed by endocytic membrane retrieval and the reformation of SVs. Recent data suggest that at physiological temperature SVs are internalized via clathrin-independent ultrafast endocytosis (UFE) within hundreds of milliseconds, while other studies have postulated a key role for clathrin-mediated endocytosis (CME) of SV proteins on a timescale of seconds to tens of seconds. Here we demonstrate using cultured hippocampal neurons as a model that at physiological temperature SV endocytosis occurs on several timescales from less than a second to several seconds, yet, is largely independent of clathrin...
February 22, 2017: Neuron
G M G Freire, R N Cavalcante, J M Motta-Leal-Filho, M Messina, F L Galastri, B B Affonso, R D Rocha, F Nasser
AIM: To evaluate if pre- and post-procedure administration of controlled-release oxycodone (CRO) in combination with standard analgesia improves pain control and decreases the amount of required post-procedure opioids in uterine fibroid embolisation (UFE). MATERIALS AND METHODS: Between January 2009 and March 2010, 60 consecutive women were prospectively randomised in two groups for UFE: the control group, in which 30 patients underwent the standard anaesthetic procedure and the CRO group, in which 30 patients underwent the standard anaesthetic procedure with the addition of CRO...
May 2017: Clinical Radiology
Stevo Duvnjak, Pernille Ravn, Anders Green, Poul Erik Andersen
Background Uterine fibroid embolization (UFE) is an effective minimally invasive treatment aimed to obtain complete fibroid infarction. Purpose To evaluate the degree of fibroid infarction after embolization with acrylamido polyvinyl alcohol microspheres (Bead Block). Material and Methods This prospective study included 26 pre-menopausal women in the period October 2013 to January 2015. UFE with the use of Bead Block microspheres 700-900 µm was obtained until flow stasis was achieved. Contrast-enhanced magnetic resonance imaging (MRI) was used to define residual contrast enhancement in the total fibroid burden and enhancement >10% was defined as insufficient embolization...
January 1, 2016: Acta Radiologica
L Marais, M Pernot, H Khettab, M Tanter, E Messas, M Zidi, S Laurent, P Boutouyrie
OBJECTIVE: The question whether arterial stiffness in hypertension is increased solely because of increased arterial pressure is not solved. Because measurement of arterial stiffness is highly dependent on measurement of blood pressure (BP), the development of methods independent of BP is necessary for clarifying this question. Ultrafast echography (UFE, Supersonic Imagine, Aix en Provence, France) makes use of very fast sampling rate (up to 10 kHz), so transient events such as pressure wave arrival can be tracked...
September 2016: Journal of Hypertension
Linda Mustelin, Vilma-Lotta Lehtokari, Anna Keski-Rahkonen
OBJECTIVE: To examine the occurrence, course, and clinical picture of the DSM-5 residual categories 'Other Specified Feeding or Eating Disorder' (OSFED) and 'Unspecified Feeding or Eating Disorder' (UFED), to describe potential subtypes, and to evaluate whether the subdivision of the residual category appears meaningful. METHOD: We screened women from the 1975-79 birth cohorts of Finnish twins (N = 2825) for lifetime eating disorders using questionnaires and the SCID interview...
July 21, 2016: International Journal of Eating Disorders
R Ruiz-Cruces, E Vano, F Carrera-Magariño, F Moreno-Rodriguez, M M Soler-Cantos, M Canis-Lopez, J Hernández-Armas, F J Diaz-Romero, F Rosales-Espizua, J M Fernandez-Soto, R Sanchez-Casanueva, A Martin-Palanca, M Perez-Martinez, A Gil-Agudo, M A Zarca-Diaz, V Parra-Osorio, J J Muñoz Ruiz-Canela, T Moreno-Sanchez, A Lopez-Medina, C Moreno-Saiz, P Galan-Montenegro, J J Gallego-Beuter, M Gonzalez-de-Garay, J C Zapata-Jimenez, J M Pastor-Vega, S Cañete
OBJECTIVES: To propose national diagnostic reference levels (DRLs) for interventional radiology and to evaluate the impact of the procedural complexity on patient doses. METHODS: Eight interventional radiology units from Spanish hospitals were involved in this project. The participants agreed to undergo common quality control procedures for X-ray systems. Kerma area product (KAP) was collected from a sample of 1,649 procedures. A consensus document established the criteria to evaluate the complexity of seven types of procedures...
December 2016: European Radiology
L I Velikanova, Z R Shafigullina, A A Lisitsin, N V Vorokhobina, K Grigoryan, E A Kukhianidze, E G Strelnikova, N S Krivokhizhina, L M Krasnov, E A Fedorov, I V Sablin, A L Moskvin, E A Bessonova
Urinary steroid profiling (USP) was studied using high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) methods in 108 patients with adrenocortical adenoma (ACA) and in 31 patients with adrenocortical carcinoma (ACC). Thirteen ACC and Cushing's syndrome (ACC-CS) patients had two types of USP as well as 18 ACC patients without hypercortisolism. These four types differed by androgen and glucocorticoid secretion of the adrenal cortex. Fifteen main ACC features were observed by GC-MS...
July 1, 2016: Hormones & Cancer
Chika C Obele, Samantha Dunham, Genevieve Bennett, Johanna Pagan, Lok Yun Sung, Hearns W Charles
Background. Since its introduction in 1996, uterine fibroid embolization (UFE) has become standard medical practice in the management of symptomatic uterine fibroids. An extremely rare complication, pyomyoma, has been reported only 5 times previously in the literature following UFE. Case. A 37-year-old woman underwent UFE for symptomatic leiomyomas of the uterus. Signs and symptoms of uterine infection ensued, beginning at 6 days following the procedure. Recurrent fevers and increasing leukocytosis despite the intravenous administration of appropriate antibiotics eventually necessitated surgical intervention on postprocedure day #18...
2016: Case Reports in Obstetrics and Gynecology
L Marais, M Pernot, H Khettab, M Tanter, E Messas, M Zidi, S Laurent, P Boutouyrie
BACKGROUND: Because measurement of arterial stiffness is highly dependent on blood pressure (BP), methods independent of BP are required. Ultrafast echography (UFE, Supersonic Imagine, Aix-en-Provence, France) makes use of very fast sampling rate (up to 10kHz), so transient events such as pressure wave arrival can be tracked. This method has never been tested against classical echotracking (Artlab, Esaote, Maastricht, NL) and carotid-femoral pulse wave velocity (cf-PWV, Sphygmocor, AtCor, Sydney, Australia)...
December 2015: Annales de Cardiologie et D'angéiologie
Katarzyna Kosicka, Anna Siemiątkowska, Mariola Krzyścin, Grzegorz H Bręborowicz, Matylda Resztak, Aleksandra Majchrzak-Celińska, Marek Chuchracki, Franciszek K Główka
OBJECTIVES: The aim of the study was to analyze the plasma and urinary cortisol (F) and cortisone (E) levels in normotensive and hypertensive pregnant women. The parameters known to reflect the function of 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) were calculated to verify the changes in glucocorticoid balance over the course of gestational hypertension (GH) and pre-eclampsia (PE). MATERIALS AND METHODS: This retrospective case-control study included women in the third trimester of pregnancy, diagnosed with: GH (n = 29), PE (n = 26), or chronic hypertension (CH; n = 22)...
2015: PloS One
Henry Caudle, Christine Pang, Sam Mancuso, David Castle, Richard Newton
BACKGROUND: This study compares the DSM-IV and DSM-5 diagnostic criteria for eating disorders. DSM-IV resulted in a large number of patients being diagnosed with Eating Disorder Not Otherwise Specified (EDNOS). In DSM-5 the residual category is renamed Other Specified Feeding and Eating Disorders (OSFED) and Unspecified Eating Disorders (UFED) however the diagnostic criteria for the residual category in each of the diagnostic systems remains the same. This study aims to evaluate the changes in percentages of patients in a residual DSM-IV category compared to a residual DSM-5 category by retrospectively applying DSM-5 criteria to the clinical records of a patient population in a clinical setting...
2015: Journal of Eating Disorders
Valentina Morelli, Elisa Polledri, Rosa Mercadante, Volha Zhukouskaya, Serena Palmieri, Paolo Beck-Peccoz, Anna Spada, Silvia Fustinoni, Iacopo Chiodini
In adrenal incidentaloma (AI) patients, beside the cortisol secretion, a different 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2) activity, measurable by 24-h urinary cortisol/cortisone ratio (R-UFF/UFE) (the higher R-UFF/UFE the lower HSD11B2 activity), could influence the occurrence of the subclinical hypercortisolism (SH)-related complications (hypertension, type 2 diabetes, obesity). We evaluated whether in AI patients, UFF levels are associated to UFE levels, and the HSD11B2 activity to the complications presence...
September 2016: Endocrine
Amir Abbas Kianfar, Zargham Hossein Ahmadi, Seyed Mohsen Mirhossein, Hamidreza Jamaati, Babak Sharif Kashani, Seyed Amir Mohajerani, Ehsan Firoozi, Farshid Salehi, Golnar Radmand, Seyed Mohammadreza Hashemian
BACKGROUND: Heart transplant surgeries using cardiopulmonary bypass (CPB) typically requires mechanical ventilation in intensive care units (ICU) in post-operation period. Ultra fast-track extubation (UFE) have been described in patients undergoing various cardiac surgeries. AIM: To determine the possibility of ultra-fast-track extubation instead of late extubation in post heart transplant patients. MATERIALS AND METHODS: Patients randomly assigned into two groups; Ultra fast-track extubation (UFE) group was defined by extubation inside operating room right after surgery...
April 2015: International Journal of Critical Illness and Injury Science
Stevo Duvnjak, Pernille Ravn, Anders Green, Poul Erik Andersen
PURPOSE: This study was designed to evaluate the long-term clinical outcome and frequency of reinterventions in patients with uterine fibroids treated with embolization at a single center using polyvinyl alcohol microparticles. METHODS: The study included all patients with symptomatic uterine fibroids treated with uterine fibroid embolization (UFE) with spherical (s-PVA) and nonspherical (ns-PVA) polyvinyl alcohol microparticles during the period January 2001 to January 2011...
February 2016: Cardiovascular and Interventional Radiology
J Tang, S Tavintharan, C Sum, S Lim, H Ong
OBJECTIVE: Renal 11 beta hydroxysteroid dehydrogenase type 2 (11BHSD2) is a key molecular player in the renin- angiotensin- aldosterone system (RAAS). We hypothesize that decreased renal 11BHSD2 activity, as measured by increased urinary free cortisol to cortisone (UFF/UFE) ratio using gas chromatography-mass spectrometry (GCMS), may be an important biomarker in identifying diabetic patients with increased left ventricular mass. DESIGN AND METHOD: We studied insulin-naive male patients with type 2 diabetes and stage 1 hypertension (blood pressure of 140-160/90-100 mmHg) in this study...
June 2015: Journal of Hypertension
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