keyword
https://read.qxmd.com/read/38488784/nih-study-provides-long-awaited-insight-into-myalgic-encephalomyelitis-chronic-fatigue-syndrome
#1
JOURNAL ARTICLE
Quinn Eastman
No abstract text is available yet for this article.
March 15, 2024: JAMA
https://read.qxmd.com/read/38485605/appraisal-of-clinical-practice-guideline-national-institute-for-health-and-care-excellence-nice-clinical-practice-guideline-for-myalgic-encephalomyelitis-or%C3%A2-encephalopathy-chronic-fatigue-syndrome-diagnosis-and-management
#2
https://read.qxmd.com/read/38483046/myalgic-encephalomyelitis-chronic-fatigue-syndrome-from-current-evidence-to-new-diagnostic-perspectives-through-skeletal-muscle-and-metabolic-disturbances
#3
REVIEW
Tiziana Pietrangelo, Stefano Cagnin, Danilo Bondi, Carmen Santangelo, Lorenzo Marramiero, Cristina Purcaro, Raphael Severino Bonadio, Ester Sara Di Filippo, Rosa Mancinelli, Stefania Fulle, Vittore Verratti, Xuanhong Cheng
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a demanding medical condition for patients and society. It has raised much more public awareness after the COVID-19 pandemic since ME/CFS and long-COVID patients share many clinical symptoms such as debilitating chronic fatigue. However, unlike long COVID, the etiopathology of ME/CFS remains a mystery despite several decades' research. This review moves from pathophysiology of ME/CFS through the compelling evidence and most interesting hypotheses...
March 14, 2024: Acta Physiologica
https://read.qxmd.com/read/38476222/editorial-cd24-in-the-regulation-of-cellular-development-and-disease
#4
EDITORIAL
Sherri L Christian, Geraldine Cambridge
No abstract text is available yet for this article.
2024: Frontiers in Immunology
https://read.qxmd.com/read/38454468/ia-pacs-cfs-a-double-blinded-randomized-sham-controlled-exploratory-trial-of-immunoadsorption-in-patients-with-chronic-fatigue-syndrome-cfs-including-patients-with-post-acute-covid-19-cfs-pacs-cfs
#5
JOURNAL ARTICLE
Hannah Preßler, Marie-Luise Machule, Friederike Ufer, Isabel Bünger, Lucie Yuanting Li, Emilie Buchholz, Claudia Werner, Esther Beraha, Frank Wagner, Matthes Metz, Susen Burock, Lisa Bruckert, Christiana Franke, Nicola Wilck, Anne Krüger, Alexander Reshetnik, Kai-Uwe Eckardt, Matthias Endres, Harald Prüss
BACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severely debilitating condition which markedly restricts activity and function of affected people. Since the beginning of the COVID-19 pandemic ME/CFS related to post-acute COVID-19 syndrome (PACS) can be diagnosed in a subset of patients presenting with persistent fatigue 6 months after a mostly mild SARS-CoV-2 infection by fulfillment of the Canadian Consensus Criteria (CCC 2003). Induction of autoimmunity after viral infection is a mechanism under intensive investigation...
March 7, 2024: Trials
https://read.qxmd.com/read/38453418/management-of-severe-me-cfs-in-children-and-young-people-in-the-uk-a-british-paediatric-surveillance-unit-study
#6
JOURNAL ARTICLE
Alexander Peter Royston, Sarah Burge, Ilaria Idini, Amberly Brigden, Katharine Claire Pike
OBJECTIVE: Severe myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) in children and young people (CYP) is a little-understood condition which significantly impacts education, development and quality of life. We used data from a population-wide surveillance study to explore the screening investigation, referral and management of suspected cases of paediatric severe ME/CFS. METHODS: A British Paediatric Surveillance Unit (BPSU) study reported cases of CYP with suspected severe ME/CFS between February 2018 and February 2019...
March 7, 2024: BMJ Paediatrics Open
https://read.qxmd.com/read/38449917/burnout-compassion-fatigue-and-the-long-haul-of-caring-for-long-covid
#7
JOURNAL ARTICLE
Christian B Ramers, John D Scott, Bruce B Struminger
The current landscape of clinician burnout is prompting the need for our health care system to revise its approach toward complex conditions such as long coronavirus disease (COVID), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and other postinfectious fatiguing illnesses (PIFIs). We discuss our efforts here at Family Health Center of San Diego (FHCSD) to help share insight and glean perspective from clinicians who have participated in our Centers for Disease Control and Prevention (CDC)-funded 3-year continuing professional development initiative...
March 2024: Open Forum Infectious Diseases
https://read.qxmd.com/read/38448223/-the-world-was-going-through-what-we-go-through-everyday-the-experiences-of-women-with-myalgic-encephalomyelitis-chronic-fatigue-syndrome-me-cfs-living-with-their-partners-during-the-covid-19-lockdown-in-the-united-kingdom
#8
JOURNAL ARTICLE
Tarnjit Sehmbi, Alison Wearden, Sarah Peters, Kimberly Dienes
OBJECTIVES: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a long-term debilitating illness characterised by profound and persistent fatigue (JAMA: The Journal of the American Medical Association, 313, 2015, 1101). The current study aims to explore the experiences of women with ME/CFS living with their partners during the COVID-19 pandemic in the United Kingdom. DESIGN: The study adopted a qualitative design comprising semi-structured interviews with participants...
March 6, 2024: British Journal of Health Psychology
https://read.qxmd.com/read/38443223/unravelling-shared-mechanisms-insights-from-recent-me-cfs-research-to-illuminate-long-covid-pathologies
#9
REVIEW
Sarah J Annesley, Daniel Missailidis, Benjamin Heng, Elisha K Josev, Christopher W Armstrong
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic illness often triggered by an initiating acute event, mainly viral infections. The transition from acute to chronic disease remains unknown, but interest in this phenomenon has escalated since the COVID-19 pandemic and the post-COVID-19 illness, termed 'long COVID' (LC). Both ME/CFS and LC share many clinical similarities. Here, we present recent findings in ME/CFS research focussing on proposed disease pathologies shared with LC...
March 4, 2024: Trends in Molecular Medicine
https://read.qxmd.com/read/38434357/identifying-the-mental-health-burden-in-myalgic-encephalomyelitis-chronic-fatigue-syndrome-me-cfs-patients-in-switzerland-a-pilot-study
#10
JOURNAL ARTICLE
Rahel Susanne König, Daniel Henry Paris, Marc Sollberger, Rea Tschopp
BACKGROUND: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating chronic disease of significant public health and clinical importance. It affects multiple systems in the body and has neuro-immunological characteristics. The disease is characterized by a prominent symptom called post-exertional malaise (PEM), as well as abnormalities in the immune-inflammatory pathways, mitochondrial dysfunctions and disturbances in neuroendocrine pathways. The purpose of this study was to evaluate the impact of ME/CFS on the mental health and secondary psychosocial manifestations of patients, as well as their coping mechanisms...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38429822/clinical-evidence-of-the-link-between-gut-microbiome-and-myalgic-encephalomyelitis-chronic-fatigue-syndrome-a-retrospective-review
#11
REVIEW
Jing-Hua Wang, Yujin Choi, Jin-Seok Lee, Seung-Ju Hwang, Jiyeon Gu, Chang-Gue Son
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a heterogeneous disorder with elusive causes, but most likely because of clinical and other biological factors. As a vital environmental factor, the gut microbiome is increasingly emphasized in various refractory diseases including ME/CFS. The present study is aimed to enhance our understanding of the relationship between the gut microbiome and ME/CFS through data analysis of various clinical studies. We conducted a literature search in four databases (PubMed, Cochrane Library, Web of Science, and Google Scholar) until May 31, 2023...
March 1, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38429546/graded-exercise-therapy-compared-to-activity-management-for-paediatric-chronic-fatigue-syndrome-myalgic-encephalomyelitis-pragmatic-randomized-controlled-trial
#12
JOURNAL ARTICLE
Daisy M Gaunt, Amberly Brigden, Shaun R S Harris, William Hollingworth, Russell Jago, Emma Solomon-Moore, Lucy Beasant, Nicola Mills, Parisa Sinai, Esther Crawley, Chris Metcalfe
The MAGENTA pragmatic parallel groups randomized controlled trial compared graded exercise therapy (GET) with activity management (AM) in treating paediatric myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS). Children aged 8-17 years with mild/moderate ME/CFS and presenting to NHS specialist paediatric services were allocated at random to either individualised flexible treatment focussing on physical activity (GET, 123 participants) or on managing cognitive, school and social activity (AM, 118 participants) delivered by NHS therapists...
March 2, 2024: European Journal of Pediatrics
https://read.qxmd.com/read/38418217/nice-guideline-on-me-cfs-robust-advice-based-on-a-thorough-review-of-the-evidence
#13
REVIEW
Peter Walter Barry, Kate Kelley, Toni Tan, Ilora Finlay
In 2021, the National Institute for Health and Care Excellence produced an evidence-based guideline on the diagnosis and management of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a disabling long-term condition of unknown cause. The guideline provides clear support for people living with ME/CFS, their families and carers, and for clinicians. A recent opinion piece published in the journal suggested that there were anomalies in the processing and interpretation of the evidence when developing the guideline and proposed eight areas where these anomalies were thought to have occurred...
February 28, 2024: Journal of Neurology, Neurosurgery, and Psychiatry
https://read.qxmd.com/read/38412735/heat-treatment-in-health-and-disease-how-water-filtered-infrared-a-wira-irradiation-affects-key-cellular-mechanisms-in-myalgic-encephalomyelitis-chronic-fatigue-syndrome-me-cfs-patients-compared-to-healthy-donors
#14
JOURNAL ARTICLE
Barbara Hochecker, Noah Molinski, Katja Matt, Alica Meßmer, Melanie Scherer, Alexander von Ardenne, Jörg Bergemann
Heat treatment or hyperthermia is a promising therapy for many diseases, especially cancer, and can be traced back thousands of years. Despite its long history, little is known about the cellular and molecular effects of heat on human cells. Therefore, we investigated the impact of water-filtered infrared-A (wIRA) irradiation (39 °C, 60 min) on key cellular mechanisms, namely autophagy, mitochondrial function and mRNA expression, in human fibroblasts and peripheral blood mononuclear cells (PBMCs) from healthy donors and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients...
February 21, 2024: Journal of Thermal Biology
https://read.qxmd.com/read/38407166/estimates-of-incidence-and-predictors-of-fatiguing-illness-after-sars-cov-2-infection
#15
JOURNAL ARTICLE
Quan M Vu, Annette L Fitzpatrick, Jennifer R Cope, Jeanne Bertolli, Nona Sotoodehnia, T Eoin West, Nikki Gentile, Elizabeth R Unger
This study aimed to estimate the incidence rates of post-COVID-19 fatigue and chronic fatigue and to quantify the additional incident fatigue caused by COVID-19. We analyzed electronic health records data of 4,589 patients with confirmed COVID-19 during February 2020-February 2021 who were followed for a median of 11.4 (interquartile range 7.8-15.5) months and compared them to data from 9,022 propensity score-matched non-COVID-19 controls. Among COVID-19 patients (15% hospitalized for acute COVID-19), the incidence rate of fatigue was 10...
March 2024: Emerging Infectious Diseases
https://read.qxmd.com/read/38406222/frequency-and-characteristics-of-chronic-fatigue-syndrome-in-multiple-sclerosis-patients-at-a-university-hospital-in-eastern-saudi-arabia
#16
JOURNAL ARTICLE
Abdullah S AlAmri, Foziah J AlShamrani, Noor M AlMohish, Azra S Zafar, Saud A Alnaaim, Hatem A Alazman, Ibrahim A Al-Ghanimi, Abdullah A AlNahdi, Fahad A AlDawsari, Shahad B AlMatrafi, Ghaida R Alzahrani, Muna S Alnamlah, Rawan A Alkhalifa
BACKGROUND: Multiple sclerosis (MS) is a chronic, inflammatory demyelinating disease that affects various parts of the central nervous system. Fatigue, a common symptom, transient, prolonged, or chronic experienced by individuals with MS, can significantly impact daily functioning. It can be associated with underlying pathological processes or can have an idiopathic cause, such as chronic fatigue syndrome (CFS). The study aimed to assess the presence and etiology of fatigue in MS patients and its relationship with CFS...
2024: Journal of Family & Community Medicine
https://read.qxmd.com/read/38405656/a-case-report-of-chronic-epipharyngitis-with-chronic-fatigue-treated-with-epipharyngeal-abrasive-therapy-eat
#17
Ito Hirobumi
A case of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) with chronic epipharyngitis was treated with epipharyngeal abrasive therapy (EAT). The symptoms of ME/CFS improved along with the improvement of chronic epipharyngitis. The patient was followed up with endocrine and autonomic function tests. Endocrine function tests included salivary cortisol and salivary α-amylase activity. Salivary α-amylase activity was stimulated by EAT. EAT improved the diurnal variability of salivary cortisol secretion...
February 2024: Curēus
https://read.qxmd.com/read/38404605/neuroplasticity-intervention-amygdala-and-insula-retraining-air-significantly-improves-overall-health-and-functioning-across-various-chronic-conditions
#18
JOURNAL ARTICLE
Alexandra J Bratty
Chronic conditions, sometimes referred to as functional somatic disorders, such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), and more recently, long COVID (LC), affect millions of people worldwide. Yet, after decades of research and testing, the etiology and treatment for many of these diseases is still unclear. Recently, a consortium of clinicians and researchers have proposed that while many different chronic conditions exist, the root cause of each may be a similar brain-body connection, as the brain responds to perceived biological threats and transmits danger signals to the body that manifest as somatic symptoms...
January 2024: Integrative Medicine
https://read.qxmd.com/read/38403179/people-with-long-covid-and-me-cfs-exhibit-similarly-impaired-dexterity-and-bimanual-coordination-a-case-case-control-study
#19
JOURNAL ARTICLE
Nilihan E M Sanal-Hayes, Lawrence D Hayes, Marie Mclaughlin, Ethan C J Berry, Nicholas F Sculthorpe
PURPOSE: Dexterity and bimanual coordination had not previously been compared between people with long COVID and people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Therefore, this study determined dexterity and bimanual coordination in people with long COVID (∼16 month illness duration; n=21) and ME/CFS (∼16 year illness duration; n=20), versus age-matched healthy controls (n=20). METHODS: Dexterity, and bimanual coordination was determined using the Purdue pegboard test...
February 23, 2024: American Journal of Medicine
https://read.qxmd.com/read/38399736/potential-beneficial-effects-of-naringin-and-naringenin-on-long-covid-a-review-of-the-literature
#20
REVIEW
Siqi Liu, Mengli Zhong, Hao Wu, Weiwei Su, Yonggang Wang, Peibo Li
Coronavirus disease 2019 (COVID-19) caused a severe epidemic due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Recent studies have found that patients do not completely recover from acute infections, but instead, suffer from a variety of post-acute sequelae of SARS-CoV-2 infection, known as long COVID. The effects of long COVID can be far-reaching, with a duration of up to six months and a range of symptoms such as cognitive dysfunction, immune dysregulation, microbiota dysbiosis, myalgic encephalomyelitis/chronic fatigue syndrome, myocarditis, pulmonary fibrosis, cough, diabetes, pain, reproductive dysfunction, and thrombus formation...
February 4, 2024: Microorganisms
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