keyword
https://read.qxmd.com/read/38635935/tumor-size-is-not-everything-advancing-radiomics-as-a-precision-medicine-biomarker-in-oncology-drug-development-and-clinical-care-a-report-of-a-multidisciplinary-workshop-coordinated-by-the-recist-working-group
#1
JOURNAL ARTICLE
Erica C Nakajima, Amber Simpson, Jan Bogaerts, Elisabeth G E de Vries, Richard Do, Elena Garalda, Greg Goldmacher, Paul E Kinahan, Philippe Lambin, Barbara LeStage, Qin Li, Frank Lin, Saskia Litière, Raquel Perez-Lopez, Nicholas Petrick, Lawrence Schwartz, Lesley Seymour, Lalitha Shankar, Scott A Laurie
Radiomics, the science of extracting quantifiable data from routine medical images, is a powerful tool that has many potential applications in oncology. The Response Evaluation Criteria in Solid Tumors Working Group (RWG) held a workshop in May 2022, which brought together various stakeholders to discuss the potential role of radiomics in oncology drug development and clinical trials, particularly with respect to response assessment. This article summarizes the results of that workshop, reviewing radiomics for the practicing oncologist and highlighting the work that needs to be done to move forward the incorporation of radiomics into clinical trials...
April 2024: JCO Precision Oncology
https://read.qxmd.com/read/38635905/brazilian-psychiatric-association-consensus-on-the-physical-structure-and-ideal-team-for-psychiatric-emergencies-services
#2
JOURNAL ARTICLE
Leonardo Baldaçara, Flávia Ismael, Daniel Kawakami, Gislene Alves da Rocha, Elie Leal de Barros Calfat, Deisy Mendes Porto, Beatriz Ferroli Cavalcante, Beatriz Plotegher Zaramella, Flávio Veloso Ribeiro, Roberto Mendes Dos Santos, Roberta Rossi Grudtner, Teng Chei Tung, Antônio Geraldo da Silva
INTRODUCTION: An integral part of Brazil's public health system, the psychiatric emergency service (PES) has been instrumental in improving qualified support for crisis situations of mental disorders, equitable, universally accessible, and humanized. The purpose of this article is to present a systematic review and consensus about the physical area and facilities, and ideal team qualified for psychiatric emergencies services on both Brazilian settings. METHODS: The authors conducted a literature search using electronic databases such as MEDLINE (PubMed), Scielo, the Cochrane Database, and documents from the WHO, the Brazilian Ministry of Health, and others deemed relevant by experts...
April 18, 2024: Revista Brasileira de Psiquiatria
https://read.qxmd.com/read/38635735/health-care-managers-perspectives-on-workforce-licensing-practice-in-ethiopia-a-qualitative-study
#3
JOURNAL ARTICLE
Eshetu Cherinet Teka, Meron Yakob Gebreyes, Endalkachew Tsedal Alemneh, Biruk Hailu Tesfaye, Firew Ayalew Desta, Yohannes Molla Asemu, Ermias Gebreyohannes Wolde, Wondimu Daniel Ashena, Samuel Mengistu, Tewodros Abebaw Melese, Fikadie Dagnew Biset, Bezawit Worku Degefu, Bethlehem Bizuayehu Kebede, Tangut Dagnew Azeze, Wudasie Teshome Shewatatek, Melese Achamo Seboka, Abera Bezabih Gebreegzi, Mekonnen Desie Degebasa, Tsedale Tafesse Lemu, Yeshiwork Eshetu Abebe, Matias Azanaw Alayu, Fatuma Ahmed Ebrahim, Eden Workneh Sahlemariam, Genet Kifle Woldesemayat, Hailemaryam Balcha Admassu, Bethlehem Shikabaw Chekol
BACKGROUND: Professional licensing bodies are valuable sources for tracking the health workforce, as many skilled health-care providers require formal training, registration, and licensure. Regulatory activities in Ethiopia were not effectively implemented due to poor follow-up and gaps in skilled human resources, budget, and information technology infrastructure. OBJECTIVE: The aim of this study was to explore and describe the lived experiences and challenges faced by health care managers in health professionals' licensure practices in Ethiopia...
2024: PloS One
https://read.qxmd.com/read/38635135/french-national-survey-on-breast-cancer-care-caregiver-and-patient-views
#4
JOURNAL ARTICLE
Christine Rousset-Jablonski, Barbara Lortal, Sophie Lantheaume, Laurent Arnould, Hélène Simon, Anne-Sophie Tuszynski, Mélanie Courtier, Soukayna Debbah, Marc Lefrançois, Sita Balbin, Anne-Sophie Kably, Alain Toledano
PURPOSE: To improve the quality of care for patients with breast cancer, an analysis of the health-care pathway, considering feedback from both health-care practitioners (HCPs) and patients, is needed. METHODS: Between 2020 and 2022, we conducted a survey at French breast cancer centers and analyzed information from questionnaires completed by HCPs and patients. We collected information on center organization, diagnostic processes, treatment decisions and modalities, supportive care, patient advocacy groups, and work issues...
April 18, 2024: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://read.qxmd.com/read/38634844/clinical-properties-and-rehabilitation-needs-of-earthquake-survivors-in-a-subacute-rehabilitation-setting
#5
JOURNAL ARTICLE
Emine Esra Bilir, Pinar Borman, Ayşe Merve Ata, Ebru Alemdaroğlu, Hatice Bodur, Burcu Yanık, Fatma Yurdakul, Bilge Kesikburun, Tuba Güler, Bedriye Başkan, Selami Akkuş, Oznur Uzun, Evren Yaşar
BACKGROUND: This descriptive analysis examines the victims of the February 6, 2023, earthquakes in Kahramanmaraş and Elbistan, Türkiye. It aims to detail the injury profiles related to neuro-musculoskeletal trauma, assess the rehabilitation needs of patients, and propose a comprehensive rehabilitation approach. METHODS: The study included patients injured in the Kahramanmaraş-centered earthquake on February 6, 2023, who were transported to our hospital based on their rehabilitation needs...
April 2024: Turkish Journal of Trauma & Emergency Surgery: TJTES
https://read.qxmd.com/read/38633186/antimicrobial-resistance-from-one-health-perspective-in-the-middle-east-a-systematic-review
#6
JOURNAL ARTICLE
Khalid A Alkheraije
BACKGROUND: Antimicrobial resistance (AMR) is recognized globally as a significant health challenge, but its extent remains unclear in many regions. It is crucial to prioritize a foundational evaluation of AMR prevalence to facilitate the implementation of laboratory-based surveillance. Adopting a One Health perspective, this study outlines the present AMR status in the Middle East. AIM: To synthesize the current state of knowledge on AMR in the Middle East, delineate the contributions of different sectors (human health, animal health, and environment), and discern the effectiveness of One Health interventions in mitigating AMR...
January 2024: Open Veterinary Journal
https://read.qxmd.com/read/38633017/building-a-regional-pediatric-asthma-learning-health-system-in-support-of-optimal-equitable-outcomes
#7
JOURNAL ARTICLE
Andrew F Beck, Michael Seid, Karen M McDowell, Mfonobong Udoko, Susan C Cronin, Dimitrios Makrozahopoulos, Tricia Powers, Sonja Fairbanks, Jonelle Prideaux, Lisa M Vaughn, Elizabeth Hente, Sophia Thurmond, Ndidi I Unaka
INTRODUCTION: Asthma is characterized by preventable morbidity, cost, and inequity. We sought to build an Asthma Learning Health System (ALHS) to coordinate regional pediatric asthma improvement activities. METHODS: We generated quantitative and qualitative insights pertinent to a better, more equitable care delivery system. We used electronic health record data to calculate asthma hospitalization rates for youth in our region. We completed an "environmental scan" to catalog the breadth of asthma-related efforts occurring in our children's hospital and across the region...
April 2024: Learning Health Systems
https://read.qxmd.com/read/38632009/optimizing-trajectories-of-social-adaptive-competencies-after-extreme-prematurity-during-the-first-1000-days
#8
REVIEW
Michael E Msall, Joanne M Lagatta, Samudragupta Bora
Over 75% of surviving extremely preterm infants do not have major neurodevelopmental disabilities; however, more than half face difficulties with communication, coordination, attention, learning, social, and executive function abilities. These "minor" challenges can have a negative impact on educational and social outcomes, resulting in physical, behavioral, and social health problems in adulthood. We will review assessment tools for social-emotional and adaptive functional skills in early childhood as these determine family and early childhood supports...
April 10, 2024: Seminars in Fetal & Neonatal Medicine
https://read.qxmd.com/read/38631798/out-of-hospital-cardiac-arrest
#9
REVIEW
Ryan B Gerecht, Jose V Nable
Survival from out-of-hospital cardiac arrest (OHCA) is predicated on a community and system-wide approach that includes rapid recognition of cardiac arrest, capable bystander CPR, effective basic and advanced life support (BLS and ALS) by EMS providers, and coordinated postresuscitation care. Management of these critically ill patients continues to evolve. This article focuses on the management of OHCA by EMS providers.
May 2024: Cardiology Clinics
https://read.qxmd.com/read/38631768/complex-regional-pain-syndrome-advances-in-epidemiology-pathophysiology-diagnosis-and-treatment
#10
REVIEW
Michael C Ferraro, Neil E O'Connell, Claudia Sommer, Andreas Goebel, Janet H Bultitude, Aidan G Cashin, G Lorimer Moseley, James H McAuley
Complex regional pain syndrome (CRPS) is a rare pain disorder that usually occurs in a limb after trauma. The features of this disorder include severe pain and sensory, autonomic, motor, and trophic abnormalities. Research from the past decade has offered new insights into CRPS epidemiology, pathophysiology, diagnosis, and treatment. Early identification of individuals at high risk of CRPS is improving, with several risk factors established and some others identified in prospective studies during the past 5 years...
May 2024: Lancet Neurology
https://read.qxmd.com/read/38631710/b-cells-and-the-coordination-of-immune-checkpoint-inhibitor-response-in-patients-with-solid-tumors
#11
REVIEW
Ronan Flippot, Marcus Teixeira, Macarena Rey-Cardenas, Lucia Carril-Ajuria, Larissa Rainho, Natacha Naoun, Jean-Mehdi Jouniaux, Lisa Boselli, Marie Naigeon, Francois-Xavier Danlos, Bernard Escudier, Jean-Yves Scoazec, Lydie Cassard, Laurence Albiges, Nathalie Chaput
Immunotherapy profoundly changed the landscape of cancer therapy by providing long-lasting responses in subsets of patients and is now the standard of care in several solid tumor types. However, immunotherapy activity beyond conventional immune checkpoint inhibition is plateauing, and biomarkers are overall lacking to guide treatment selection. Most studies have focused on T cell engagement and response, but there is a growing evidence that B cells may be key players in the establishment of an organized immune response, notably through tertiary lymphoid structures...
April 16, 2024: Journal for Immunotherapy of Cancer
https://read.qxmd.com/read/38631067/makkah-healthcare-cluster-response-challenges-and-interventions-during-covid-19-pandemic-a-qualitative-study
#12
JOURNAL ARTICLE
Turky J Arbaein, Khulud K Alharbi, Afrah A Alfahmi, Khawlah O Alharthi, Sarah S Monshi, Ali M Alzahrani, Sanaa Alkabi
BACKGROUND: The global COVID-19 crisis has underscored the critical role of effective decision-making in healthcare systems. Saudi Arabia has shown resilience by implementing comprehensive testing, tracing, and vaccination measures. Given the unique cultural and religious characteristics of Makkah, specific challenges have prompted efforts to uncover local pandemic responses. This qualitative assessment aims to delineate the challenges faced by decision-makers during COVID-19 in Makkah and identify key interventions implemented by the Makkah healthcare cluster to manage and coordinate care...
April 16, 2024: Journal of Infection and Public Health
https://read.qxmd.com/read/38630586/evaluating-the-validity-of-the-nursing-statements-algorithmically-generated-based-on-the-international-classifications-of-nursing-practice-for-respiratory-nursing-care-using-large-language-models
#13
JOURNAL ARTICLE
Hyeoneui Kim, Hyewon Park, Sunghoon Kang, Jinsol Kim, Jeongha Kim, Jinsun Jung, Ricky Taira
OBJECTIVE: This study aims to facilitate the creation of quality standardized nursing statements in South Korea's hospitals using algorithmic generation based on the International Classifications of Nursing Practice (ICNP) and evaluation through Large Language Models. MATERIALS AND METHODS: We algorithmically generated 15 972 statements related to acute respiratory care using 117 concepts and concept composition models of ICNP. Human reviewers, Generative Pre-trained Transformers 4...
April 17, 2024: Journal of the American Medical Informatics Association: JAMIA
https://read.qxmd.com/read/38630037/-ketamin-a-harmful-recreational-drug
#14
JOURNAL ARTICLE
Romaine Delacrétaz, Line Guillod, Kathia Bornand, Salomé Clemens, Anne-Emmanuelle Ambresin
Adolescence is a developmental phase that exposes young people to exploratory behaviors, including substance abuse. In Switzerland, recreational ketamine use among young people is on the rise and is likely to lead to irreversible somatic complications. Primary care physicians play an essential role in identifying ketamine users, and should offer brief interventions, risk-reduction advice and a psychosocial assessment of the situation, involving close relatives. In the event of secondary damage, particularly urological damage, coordinated management by specialists is essential to achieve symptom regression...
April 17, 2024: Revue Médicale Suisse
https://read.qxmd.com/read/38629670/implementation-of-a-digital-tool-for-population-management-in-primary-health-care
#15
JOURNAL ARTICLE
Debora Paulino da Silva Almeida, Paulo Leandro de Oliveira Junior, Glauber Alves Dos Prazeres, Lorrayne Belotti, Jessica Domingues, Natalia Martins Bonassi, Ilana Eshriqui, Renata Soares Martins, Leticia Yamawaka de Almeida, Daiana Bonfim
OBJECTIVE: Describe the implementation of a digital diagnostic and territorial monitoring tool in primary healthcare. METHODS: Quantitative and qualitative study, developed in 14 basic healthcare units in São Paulo, with community health workers, coordinators, nurses, and physicians. Data collection occurred in four phases: analysis of the instruments used by the team for territory management; development of the digital tool; training and implementation; and evaluation after 90 days using focus groups...
2024: Revista de Saúde Pública
https://read.qxmd.com/read/38628303/implementation-and-evaluation-of-a-trainee-orientation-manual-in-an-intensive-care-unit-rotation
#16
JOURNAL ARTICLE
Maria C Cañizares-Otero, Aunie M Danyalian, Daniel P High, Pamela Vieira, Christian Almanzar Zorilla, Jasmine Dew, Chi Chan Lee, Idle M Lee, Raiko Diaz, Daniel Zapata, Mauricio Danckers
BACKGROUND: The intensive care unit (ICU) rotation places trainees in a fast-paced, high-intensity environment that requires complex patient care and multidisciplinary coordination. Trainees seek continuous medical knowledge acquisition while tasked with learning ICU-specific workflows, procedures, and policies. The unfamiliarity with rotation logistics and administrative roles and expectations could hinder the ICU rotation learning experience. A lack of standardization and material for trainee orientation to administrative ICU tasks and workflows could affect the trainee's rotation performance and overall learner satisfaction...
March 2024: ATS scholar
https://read.qxmd.com/read/38628150/decoding-the-persistence-of-delayed-hospital-discharge-an-in-depth-scoping-review-and-insights-from-two-decades
#17
JOURNAL ARTICLE
Alyaa Abdelhalim, Manaf Zargoush, Norm Archer, Mehrdad Roham
OBJECTIVE: This article addresses the persistent challenge of Delayed Hospital Discharge (DHD) and aims to provide a comprehensive overview, synthesis, and actionable, sustainable plan based on the synthesis of the systematic review articles spanning the past 24 years. Our research aims to comprehensively examine DHD, identifying its primary causes and emphasizing the significance of effective communication and management in healthcare settings. METHODS: We conducted the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) method for synthesizing findings from 23 review papers published over the last two decades, encompassing over 700 studies...
April 2024: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://read.qxmd.com/read/38627138/kidney-transplantation-during-covid-19-outbreak-data-from-public-and-non-public-dialysis-network
#18
JOURNAL ARTICLE
Jacek Zawierucha, Wojciech Marcinkowski, Jacek Małyszko, Jolanta Małyszko
BACKGROUND: The COVID-19 pandemic significantly affected medical services in Poland. All restrictions, additional procedures, and numerous infections among medical staff affected transplantation in the country. This study aimed to analyze reports prepared by the Polish Transplant Coordination Center Poltransplant and internal Fresenius Nephrocare Poland to assess differences in the number of patients who qualified for kidney transplantation and transplanted during the pandemic compared with a pre-pandemic year...
April 15, 2024: Transplantation Proceedings
https://read.qxmd.com/read/38626216/double-duty-caregivers-enduring-covid-19-pandemic-to-endemic-it-s-just-wearing-me-down
#19
JOURNAL ARTICLE
Jasneet Parmar, Tanya L'Heureux, Michelle Lobchuk, Jamie Penner, Lesley Charles, Oona St Amant, Catherine Ward-Griffin, Sharon Anderson
The COVID-19 pandemic has considerably strained health care providers and family caregivers. Double-duty caregivers give unpaid care at home and are employed as care providers. This sequential mixed-method study, a survey followed by qualitative interviews, aimed to comprehensively understand the experiences of these Canadian double-duty caregivers amidst the pandemic and the transition to the endemic phase. The multi-section survey included standardized assessments such as the Double-duty Caregiver Scale and the State Anxiety Scale, along with demographic, employment-related, and care work questions...
2024: PloS One
https://read.qxmd.com/read/38625976/patterns-of-interactions-among-icu-interprofessional-teams-a-prospective-patient-shift-level-survey-approach
#20
JOURNAL ARTICLE
Hannah C Ratliff, Olga Yakusheva, Emily M Boltey, Deanna J Marriott, Deena Kelly Costa
BACKGROUND: The Awakening, Breathing Coordination, Delirium monitoring and Early mobility bundle (ABCDE) is associated with lower mortality for intensive care unit (ICU) patients. However, efforts to improve ABCDE are variably successful, possibly due to lack of clarity about who are the team members interacting when caring for each patient, each shift. Lack of patient shift-level information regarding who is interacting with whom limits the ability to tailor interventions to the specific ICU team to improve ABCDE...
2024: PloS One
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