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https://www.readbyqxmd.com/read/28633947/occurrence-and-spatial-distribution-of-organophosphorus-flame-retardants-and-plasticizers-in-the-bohai-and-yellow-seas-china
#1
Mingyu Zhong, Jianhui Tang, Lijie Mi, Fei Li, Runmei Wang, Guopei Huang, Huifeng Wu
Seawater samples from 50 sites in the BS and YS were collected to investigate the spatial distribution of 7 OPs. Concentrations of the total OPs (ƩOPs) in the BS and YS ranged from 8.12ngL(-1) to 98.04ngL(-1) with a geometric mean (GM) of 23.70ngL(-1). Tris(1-chloro-2-propyl) phosphate (TCPP) was the dominant compound, followed by tris(2-chloroethyl) phosphate (TCEP) and triphenylphosphine oxide (TPPO). The ƩOPs together with the most commonly detected individual OPs (TCPP, TCEP, tris(1,3-dichloro-2-propyl) phosphate (TDCPP), tri-iso-butyl phosphate (TiBP), triphenyl phosphate (TPhP), and TPPO) tended to decrease from nearshore to offshore and from the surface to the bottom seawaters, indicating major land-based sources...
June 17, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28623089/optimal-intrathecal-hyperbaric-bupivacaine-dose-with-opioids-for-cesarean-delivery-a-prospective-double-blinded-randomized-trial
#2
Eiko Onishi, Mamoru Murakami, Keiji Hashimoto, Miho Kaneko
BACKGROUND: Single-shot spinal anesthesia is commonly used for cesarean delivery. Achieving adequate anesthesia throughout surgery needs to be balanced with associated complications. We investigated the optimal dose of intrathecal hyperbaric bupivacaine, co-administered with opioids, for anesthesia for cesarean delivery. METHODS: This prospective, randomized, double-blinded, dose-ranging trial included parturients scheduled to undergo cesarean delivery under spinal anesthesia...
April 13, 2017: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/28621984/lattice-effects-on-nematic-quantum-criticality-in-metals
#3
I Paul, M Garst
Theoretically, it is commonly held that in metals near a nematic quantum critical point the electronic excitations become incoherent on the entire "hot" Fermi surface, triggering non-Fermi-liquid behavior. However, such conclusions are based on electron-only theories, ignoring a symmetry-allowed coupling between the electronic nematic variable and a suitable crystalline lattice strain. Here, we show that including this coupling leads to entirely different conclusions because the critical fluctuations are mostly cut off by the noncritical lattice shear modes...
June 2, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28621286/endodontic-management-of-dilacerated-maxillary-central-incisor-fused-to-a-supernumerary-tooth-using-cone-beam-computed-tomography-an-unusual-clinical-presentation
#4
Thilla S Vinothkumar, Deivanayagam Kandaswamy, Ganesh Arathi, Sathishkumar Ramkumar, Gnanasekaran Felsypremila
AIM: The purpose of this report is to present a case of endodontic management of a dilacerated maxillary central incisor fused to supernumerary tooth unusually appearing as a labial tubercle using cone beam computed tomography (CBCT) as a diagnostic aid. BACKGROUND: Anterior teeth are commonly encountered with aberrant anatomical variations in the crown, number of roots, and root canals. Fusion is an infrequent developmental abnormality in shape of the tooth caused by the union of two adjacent tooth germs...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28616176/adaptation-to-fluctuating-environments-in-a-selection-experiment-with-drosophila-melanogaster
#5
Olga I Kubrak, Sören Nylin, Thomas Flatt, Dick R Nässel, Olof Leimar
A fundamental question in life-history evolution is how organisms cope with fluctuating environments, including variation between stressful and benign conditions. For short-lived organisms, environments commonly vary between generations. Using a novel experimental design, we exposed wild-derived Drosophila melanogaster to three different selection regimes: one where generations alternated between starvation and benign conditions, and starvation was always preceded by early exposure to cold; another where starvation and benign conditions alternated in the same way, but cold shock sometimes preceded starvation and sometimes benign conditions; and a third where conditions were always benign...
June 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28616088/effect-of-prophylactic-administration-of-novafen-for-periodontal-surgery-on-postoperative-pain-relief
#6
A Kashefimehr, A Babaloo, M Ghanizadeh, S H Ghasemi, H Mollazadeh
Pain is a subjective feeling and one of the defense and alerting mechanisms of the body, which is distinguished from the body senses, including touch sensation and perception of heat, cold, pressure, etc. Pain, discomfort, and edema are very common after dental procedures, especially after periodontal surgeries, usually occurring during the first 24 hours after surgery; such pains are classified as medium to severe pains. Generally, medications are used to manage patients' pain and discomfort. One of the most commonly used medications for pain control is Ibuprofen, which is one of the NSAIDs and is a simple derivative of phenylpropionic acid...
April 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28614409/environmental-control-of-asexual-reproduction-and-somatic-growth-of-aurelia-spp-cnidaria-scyphozoa-polyps-from-the-adriatic-sea
#7
Nathan Hubot, Cathy H Lucas, Stefano Piraino
Polyps of two moon jellyfish species, Aurelia coerulea and A. relicta, from two Adriatic Sea coastal habitats were incubated under multiple combinations of temperature (14, 21°C), salinity (24, 37 ppt) and food regime (9.3, 18.6, 27.9 μg C ind-1 week-1) to comparatively assess how these factors may influence major asexual reproduction processes in the two species. Both species exhibited a shared pattern of budding mode (Directly Budded Polyps: DBP; Stolonal Budded Polyps: SBP), with DBP favoured under low food supply (9...
2017: PloS One
https://www.readbyqxmd.com/read/28612694/-anticholinergic-syndrome-caused-by-contaminated-herbal-tea-acting-swiftly-to-identify-the-source
#8
C Oerlemans, I de Vries, A J H P van Riel
BACKGROUND: Despite good manufacturing practice and quality control, consumer products can become contaminated. In some cases, this can result in severe and life-threatening intoxication with potentially fatal consequences. CASE DESCRIPTION: A 27-year-old man and a 28-year-old pregnant woman presented to the Emergency Department with severe anticholinergic syndrome after using a marshmallow root (Althaea officinalis) herbal remedy, mixed into hot chocolate drink, to reduce symptoms of common cold...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28611217/rna-target-profiles-direct-the-discovery-of-virulence-functions-for-the-cold-shock-proteins-cspc-and-cspe
#9
Charlotte Michaux, Erik Holmqvist, Erin Vasicek, Malvika Sharan, Lars Barquist, Alexander J Westermann, John S Gunn, Jörg Vogel
The functions of many bacterial RNA-binding proteins remain obscure because of a lack of knowledge of their cellular ligands. Although well-studied cold-shock protein A (CspA) family members are induced and function at low temperature, others are highly expressed in infection-relevant conditions. Here, we have profiled transcripts bound in vivo by the CspA family members of Salmonella enterica serovar Typhimurium to link the constitutively expressed CspC and CspE proteins with virulence pathways. Phenotypic assays in vitro demonstrated a crucial role for these proteins in membrane stress, motility, and biofilm formation...
June 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28611031/cpt1a-missense-mutation-associated-with-fatty-acid-metabolism-and-reduced-height-in-greenlanders
#10
Line Skotte, Anders Koch, Victor Yakimov, Sirui Zhou, Bolette Søborg, Mikael Andersson, Sascha W Michelsen, Johan E Navne, Jacqueline M Mistry, Patrick A Dion, Michael L Pedersen, Malene L Børresen, Guy A Rouleau, Frank Geller, Mads Melbye, Bjarke Feenstra
BACKGROUND: Inuit have lived for thousands of years in an extremely cold environment on a diet dominated by marine-derived fat. To investigate how this selective pressure has affected the genetic regulation of fatty acid metabolism, we assessed 233 serum metabolic phenotypes in a population-based sample of 1570 Greenlanders. METHODS AND RESULTS: Using array-based and targeted genotyping, we found that rs80356779, a p.Pro479Leu variant in CPT1A, was strongly associated with markers of n-3 fatty acid metabolism, including degree of unsaturation (P=1...
June 2017: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/28607888/postoperative-pain-in-adult-tonsillectomy-is-there-any-difference-between-the-technique
#11
Itziar Álvarez Palacios, Ricardo González-Orús Álvarez-Morujo, Cristina Alonso Martínez, Alejandra Ayala Mejías, Oscar Arenas Brítez
Tonsillectomy is one of the most common surgical procedures performed worldwide. Several techniques have been developed to reduce morbidity and enhance recovery after tonsillectomy. Our study was designed to compare post-operative pain with three different techniques: cold dissection (CD), monopolar-bipolar dissection (MBD) and coblation dissection (CBD). 103 adults were scheduled for elective tonsillectomy from September 2014 to December 2015, and were randomized to CD, MBD and CBD. Post-operative pain was assessed using visual analogue scale (VAS) and Lattinen Test (LT)...
June 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28607793/the-case-of-reactive-arthritis-secondary-to-echinococcus-infestation
#12
Bülent Alım, Sinan Çetinel, M Alperen Servi, Fahrettin Bostancı, Mehmet Ozan Bingöl
Reactive arthritis is an inflammatory joint disease that develops after an infection and it usually occurs following a gastrointestinal or genitourinary system infection and it belongs to the family of arthritis called "spondyloarthritis." We wanted to represent a rare case of reactive arthritis secondary to Echinococcus infestation. Cyst hydatid disease is common in endemic regions like Turkey. Internal organ involvements, especially liver and lung, are most frequent involvements. Primary bone involvement is rare complication of Echinococcus infestation...
2017: Case Reports in Rheumatology
https://www.readbyqxmd.com/read/28606988/recurrent-rhinovirus-infections-in-a-child-with-inherited-mda5-deficiency
#13
Ian T Lamborn, Huie Jing, Yu Zhang, Scott B Drutman, Jordan K Abbott, Shirin Munir, Sangeeta Bade, Heardley M Murdock, Celia P Santos, Linda G Brock, Evan Masutani, Emmanuel Y Fordjour, Joshua J McElwee, Jason D Hughes, Dave P Nichols, Aziz Belkadi, Andrew J Oler, Corinne S Happel, Helen F Matthews, Laurent Abel, Peter L Collins, Kanta Subbarao, Erwin W Gelfand, Michael J Ciancanelli, Jean-Laurent Casanova, Helen C Su
MDA5 is a cytosolic sensor of double-stranded RNA (ds)RNA including viral byproducts and intermediates. We studied a child with life-threatening, recurrent respiratory tract infections, caused by viruses including human rhinovirus (HRV), influenza virus, and respiratory syncytial virus (RSV). We identified in her a homozygous missense mutation in IFIH1 that encodes MDA5. Mutant MDA5 was expressed but did not recognize the synthetic MDA5 agonist/(ds)RNA mimic polyinosinic-polycytidylic acid. When overexpressed, mutant MDA5 failed to drive luciferase activity from the IFNB1 promoter or promoters containing ISRE or NF-κB sequence motifs...
June 12, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28601505/heat-and-chemical-treatments-in-adult-cyprinus-carpio-pisces-cypriniformes-rapidly-produce-sterile-gonads
#14
Sullip Kumar Majhi, Avinash Rambhau Rasal, Basdeo Kushwaha, Sudhir Raizada
Several options have been proposed for eradication of germ cells (GCs) in mammals such as treatment with cytotoxic drugs, irradiation, cold ischemia and hyperthermic treatment. Some of these methods have been also tried in fish but conditions for complete sterilisation of gonads have not been established. Here, we report the production of sterile adult common carp Cyprinus carpio in 10 weeks by the heat and chemical treatments. The cytotoxic drug busulfan (40mg/kg) was intraperitoneally injected into the animals at 2-week intervals (5 doses in total), and they were maintained in water at 38°C between Weeks 1 and 10...
June 3, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28599066/rhinovirus-and-pre-school-wheeze
#15
REVIEW
Katarina Stenberg-Hammar, Gunilla Hedlin, Cilla Söderhäll
Rhinovirus (RV) known as the common cold virus generally only causes a mild upper respiratory infection, but severe lower respiratory symptoms have been associated with RV infections especially in asthmatic individuals. Wheezing is a symptom of airway obstruction, and preschool children wheezing with RV have been associated with increased risk of asthma at school age. There are however conflicting opinions as to whether there are differences in response to RV infection or if wheezing with RV reveals a preexisting impairment that promotes asthma mainly in predisposed children...
June 9, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28598766/tonsil-surgery-in-sweden-2013-2015-indications-surgical-methods-and-patient-reported-outcomes-from-the-national-tonsil-surgery-register
#16
Niclas Hallenstål, Ola Sunnergren, Elisabeth Ericsson, Claes Hemlin, Anne-Charlotte Hessén Söderman, Pia Nerfeldt, Erik Odhagen, Marie Ryding, Joacim Stalfors
AIM: To describes how tonsil surgery was performed in Sweden from 2013 to 2015 with data from the National Tonsil Surgery Registry in Sweden (NTSRS). METHOD: The registry collects data from both professionals and patients through questionnaires. A total of 33,870 tonsil surgeries were analysed, comprising approximately 80% of all tonsil surgeries in Sweden from 2013 to 2015. RESULTS: The two most common procedures were tonsillectomy (41%) and tonsillotomy with adenoidectomy (38%)...
June 9, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28596431/nonalcoholic-fatty-liver-disease-in-chronic-obstructive-pulmonary-disease
#17
Damien Viglino, Ingrid Jullian-Desayes, Mélanie Minoves, Judith Aron-Wisnewsky, Vincent Leroy, Jean-Pierre Zarski, Renaud Tamisier, Marie Joyeux-Faure, Jean-Louis Pépin
Nonalcoholic fatty liver disease (NAFLD) is independently linked to cardiometabolic morbidity and mortality. Low-grade inflammation, oxidative stress and ectopic fat, common features of chronic obstructive pulmonary disease (COPD), might contribute to the development of NAFLD.We aimed to investigate the prevalence of NAFLD and to evaluate the relationship between various types of liver damage and COPD severity, comorbidities and circulating inflammatory cytokines. Validated noninvasive tests (FibroMax: SteatoTest, NashTest and FibroTest) were used to assess steatosis, nonalcoholic steatohepatitis (NASH) and liver fibrosis...
June 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28595610/the-efficacy-and-safety-of-danggui-sayuk-ga-osuyu-saenggang-tang-on-korean-patients-with-cold-hypersensitivity-in-the-hands-study-protocol-for-a-pilot-double-blind-randomized-placebo-controlled-parallel-group-clinical-trial
#18
Youme Ko, Ho-Yeon Go, Yoon-Young Cho, Ji-Hye Shin, Tae-Hoon Kim, Dong-Jun Choi, Jin-Moo Lee, Jun-Bok Jang, Yun-Kyung Song, Seong-Gyu Ko, Seung-Ho Sun, Chan-Yong Jeon
BACKGROUND: In recent years, cold hypersensitivity in the hands (CHH) has become a common ailment of women in Korea. It can lead to gynecological problems such as irregular menstruation, miscarriage, and infertility. Traditionally, Korean herbal medicine has been the primary treatment method used to balance thermoregulation in the human body; however, its effectiveness has not been confirmed through systematic study. Thus, in this trial, we will investigate the feasibility of a full randomized clinical trial, Danggui-Sayuk-Ga-Osuyu-Saenggang-tang (DSGOST) in Korean women with CHH...
June 8, 2017: Trials
https://www.readbyqxmd.com/read/28593715/can-animal-habitat-use-patterns-influence-their-vulnerability-to-extreme-climate-events-an-estuarine-sportfish-case-study
#19
Ross E Boucek, Michael R Heithaus, Rolando Santos, Philip Stevens, Jennifer S Rehage
Global climate forecasts predict changes in the frequency and intensity of extreme climate events (ECEs). The capacity for specific habitat patches within a landscape to modulate stressors from extreme climate events, and animal distribution throughout habitat matrices during events, could influence the degree of population level effects following the passage of ECEs. Here, we ask (i) does the intensity of stressors of an ECE vary across a landscape? And (ii) Do habitat use patterns of a mobile species influence their vulnerability to ECEs? Specifically, we measured how extreme cold spells might interact with temporal variability in habitat use to affect populations of a tropical, estuarine-dependent large-bodied fish Common Snook, within Everglades National Park estuaries (FL US)...
June 8, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28593025/ziziphus-nummularia-inhibits-inflammation-induced-atherogenic-phenotype-of-human-aortic-smooth-muscle-cells
#20
Manal Fardoun, Tuqa Al-Shehabi, Ahmed El-Yazbi, Khodr Issa, Fouad Zouein, Dina Maaliki, Rabah Iratni, Ali H Eid
Cardiovascular disease (CVD) continues to be the leading cause of death worldwide. Atherosclerosis is a CVD characterized by plaque formation resulting from inflammation-induced insults to endothelial cells, monocytes, and vascular smooth muscle cells (VSMCs). Despite significant advances, current treatments for atherosclerosis remain insufficient, prompting the search for alternative modalities, including herbal medicine. Ziziphus nummularia is an herb commonly used in the amelioration of symptoms associated with many health conditions such as cold, diarrhea, cancer, and diabetes...
2017: Oxidative Medicine and Cellular Longevity
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