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https://www.readbyqxmd.com/read/28822870/maternal-obesity-and-attention-related-symptoms-in-the-preterm-offspring
#1
Jelske W van der Burg, Elizabeth T Jensen, Margot van de Bor, Robert M Joseph, T Michael O'Shea, Karl Kuban, Elizabeth N Allred, Megan Scott, Scott Hunter, Stephen R Hooper, Olaf Dammann, Alan Leviton
BACKGROUND: Maternal pre-pregnancy obesity, in term-born children, is associated with an increased risk of attention problems, however this relationship has not been explored among children born extremely preterm. AIM: To estimate the risk of attention problems at age 10years in children born very preterm to overweight (i.e., body mass index (BMI) 25-29kg/m(2)) and obese (i.e., BMI≥30kg/m(2)) women relative to the risk among children born to women who were neither overweight nor obese (i...
August 17, 2017: Early Human Development
https://www.readbyqxmd.com/read/28822452/-a-study-on-the-correlation-between-neo-bioscoresystem-and-disease-free-survival-of-breast-cancer-patients-with-neoadjuvant-chemotherapy
#2
G C Wang, F R Xu, J B Li, W Liu, L Bian, S H Zhang, T Wang, S T Song, Z F Jiang
Obiective: To explorethe correlation between Neo-Bioscore and disease-free survival (DFS) after neoadjuvant therapy in patients with breast cancer in China. Methods: The clinical and pathological data of 429 patients with early or locally advanced breast cancer who received neoadjuvant therapy at the No.307 Hospital of PLA from January 1, 2005 to December 31, 2015 were analyzed and we followed up their DFS. Results: Neo-Bioscore were closely related to DFS (χ(2)=47.662, P<0.001). When the groups were divided by Neo-Bioscore 3, they weremore relevantto DFS (HR=5...
August 8, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28822078/prognostic-implication-of-the-primary-tumor-location-in-early-stage-breast-cancer-focus-on-lower-inner-zone
#3
Jiqiao Yang, Shenli Tang, Yuting Zhou, Juanjuan Qiu, Juying Zhang, Sui Zhu, Qing Lv
BACKGROUND: The aim of this study was to investigate the prognostic significance of tumor location of lower inner zone (LIZ) on the survival of patients with early-stage breast cancer. METHODS: We retrospectively identified 961 breast cancer patients from Jan 2000 to Apr 2016 from hospital database. We evaluated overall survival (OS) and disease-free survival (DFS) in patients with tumors in and outside LIZ. Subgroup analyses were performed according to clinicopathological characteristics and treatment strategies...
August 18, 2017: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/28820693/clinical-features-of-intermittent-migratory-swelling-caused-by-gnathostomiasis-with-complete-follow-up
#4
Chollasap Sharma, Watcharapong Piyaphanee, Dorn Watthanakulpanich
A 15-year-old Thai girl was referred to the Hospital for Tropical Diseases of Mahidol University with a 3-week history of an intermittent migratory mass on the forehead. She was diagnosed with cutaneous gnathostomiasis. The patient was treated with albendazoleat 400 mg orally twice a day for 3 weeks, with good compliance. She revisited the hospital after 3 months and was seen to have been unresponsive to the initial treatment. There was intermittent swelling in her right upper eyelid along with mild redness around her right upper and lower eyelids...
August 7, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28820219/mo-doped-ni2p-nanowire-arrays-an-efficient-electrocatalyst-for-the-hydrogen-evolution-reaction-with-enhanced-activity-at-all-ph-values
#5
Yiqiang Sun, Lifeng Hang, Qi Shen, Tao Zhang, Huilin Li, Xiaomin Zhang, Xianjun Lyu, Yue Li
We report the successful synthesis of Mo doped Ni2P nanowires (NWs) on a Ni foam (NF) substrate by a two-step strategy, which could be used as an efficient and stable hydrogen evolution reaction (HER) electrocatalyst over the whole pH range (0-14). Electrochemical investigations demonstrated that Mo doping made the catalytic activity of Ni2P significantly enhanced. To achieve a current density of 10 mA cm(-2), Mo-Ni2P NWs/NF required an overpotential of 67 mV in acidic solution, 78 mV in alkaline solution and 84 mV in neutral solution...
August 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28820214/mediated-water-electrolysis-in-biphasic-systems
#6
Micheál D Scanlon, Pekka Peljo, Lucie Rivier, Heron Vrubel, Hubert H Girault
The concept of efficient electrolysis by linking photoelectrochemical biphasic H2 evolution and water oxidation processes in the cathodic and anodic compartments of an H-cell, respectively, is introduced. Overpotentials at the cathode and anode are minimised by incorporating light-driven elements into both biphasic reactions. The concepts viability is demonstrated by electrochemical H2 production from water splitting utilising a polarised water-organic interface in the cathodic compartment of a prototype H-cell...
August 18, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28819499/multiple-jejunal-perforation-secondary-to-intestinal-tuberculosis-infection-a-case-report
#7
Anthony Lyonga Ngonge, Domin Sone Majunda Ekaney, Carlson-Babila Sama, Joffi Musonge-Effoe, Valery Sammah Effoe, Gerald Ekwen
Abdominal tuberculosis (TB) may affect any part of the gastrointestinal tract resulting in significant morbidity and mortality. There is an increase in the incidence of abdominal TB favored by the emergence of multi-drug resistant Mycobacterium tuberculosis and immunosuppression especially from HIV co-infection. Our case is that of a 31 year old HIV-positive woman, adherent to antiretroviral therapy, who presented with a 2 month history of progressive abdominal distention, drenching night sweat and fatigue, but without fever...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28817565/peer-violence-perpetration-and-victimization-prevalence-associated-factors-and-pathways-among-1752-sixth-grade-boys-and-girls-in-schools-in-pakistan
#8
Rozina Karmaliani, Judith Mcfarlane, Rozina Somani, Hussain Maqbool Ahmed Khuwaja, Shireen Shehzad Bhamani, Tazeen Saeed Ali, Saleema Gulzar, Yasmeen Somani, Esnat D Chirwa, Rachel Jewkes
BACKGROUND: Child peer violence is a global problem and seriously impacts health and education. There are few research studies available in Pakistan, or South Asia. We describe the prevalence of peer violence, associations, and pathways between socio-economic status, school performance, gender attitudes and violence at home. METHODS: 1752 children were recruited into a cluster randomized controlled trial conducted on 40 fairly homogeneous public schools (20 for girls and 20 for boys), in Hyderabad, Pakistan...
2017: PloS One
https://www.readbyqxmd.com/read/28817534/radius-regeneration-after-open-fracture-and-extrusion-a-case-report
#9
Kristopher B McCall, David Y Chong
A pediatric patient presenting with an open forearm fracture with segmental defect is rare, and the pediatric orthopedic literature to guide treatment is sparse. There are several described methods to treat the defect, including bone grafting and bone transport techniques. In addition, there are reports of fibular regeneration after resection if the periosteum is left intact. We present a case report of complete regeneration of over half of a pediatric radial shaft with an intact periosteum, after traumatic extrusion from an open fracture...
August 16, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28816932/postmenopausal-choriocarcinoma-a-rare-case-report-and-review-of-the-literature
#10
Na Guo, Rutie Yin, Qingli Li, Liang Song, Danqing Wang
OBJECTIVE: Choriocarcinoma is rare in postmenopausal women, and an early diagnosis contributes to a potential cure. METHODS: We report a rare case of a postmenopausal woman with choriocarcinoma. The 61-year-old patient presented with irregular vaginal bleeding, 11 years after menopause and 30 years after the birth of the last child. RESULTS: Radiological investigation found a 3-cm mass on the lower left part of the vaginal wall, and also bilateral lung nodules...
August 14, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28816851/clinical-practice-guideline-safe-medication-use-in-the-icu
#11
Sandra L Kane-Gill, Joseph F Dasta, Mitchell S Buckley, Sandeep Devabhakthuni, Michael Liu, Henry Cohen, Elisabeth L George, Anne S Pohlman, Swati Agarwal, Elizabeth A Henneman, Sharon M Bejian, Sean M Berenholtz, Jodie L Pepin, Mathew C Scanlon, Brian S Smith
OBJECTIVE: To provide ICU clinicians with evidence-based guidance on safe medication use practices for the critically ill. DATA SOURCES: PubMed, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, CINAHL, Scopus, and ISI Web of Science for relevant material to December 2015. STUDY SELECTION: Based on three key components: 1) environment and patients, 2) the medication use process, and 3) the patient safety surveillance system...
September 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28816835/acute-worsening-of-tics-on-varenicline
#12
Shivam Om Mittal, Bryan T Klassen, Anhar Hassan, James H Bower, Elizabeth A Coon
OBJECTIVE: The aim of this study was to report worsening of Tourette syndrome (TS) in 2 patients treated with varenicline. BACKGROUND: Abnormal dopaminergic signaling is likely involved in the pathophysiology of TS. Varenicline is a partial α4β2 nicotinic acetylcholine agonist that enhances dopamine release. Therefore, the use of varenicline may influence tics in patients with TS. METHOD: We analyzed and described 2 case studies on patients with significant worsening of tics after treatment with varenicline...
August 14, 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28816796/intrathecal-infusion-of-haploidentical-nondonor-lymphocytes-for-central-nervous-system-leukemic-relapse-after-haploidentical-hematopoietic-stem-cell-transplantation
#13
Azusa Mayumi, Akihisa Sawada, Aya Ioi, Kohei Higuchi, Mariko Shimizu, Maho Sato, Masahiro Yasui, Masami Inoue
Leukemic relapse in the central nervous system (CNS) after conventional treatment is associated with a poor prognosis. The effectiveness and safety of IV infusion of human leukocyte antigen (HLA)-mismatched lymphocytes for leukemia, and intrathecal (IT) infusion of HLA-mismatched lymphocytes for cerebrospinal fluid (CSF) dissemination of medulloblastoma have been reported. A 13-year-old girl (HLA-A31) was diagnosed as relapsing from Philadelphia chromosome-positive acute leukemia in the CNS after receiving chemotherapy, tyrosine kinase inhibitors, haploidentical hematopoietic stem cell transplantation (HSCT) from her father (HLA-A31), and craniospinal irradiation...
August 14, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28816176/-severely-increased-serum-lipid-levels-in-diabetic-ketoacidosis-case-report
#14
Hrafnkell Stefansson, Kristinn Sigvaldason, Hilmar Kjartansson, Helga Águsta Sigurjonsdottir
Severe hypertriglyceridemia is a known, but uncommon complication of diabetic ketoacidosis. We discuss the case of a 23-year-old, previously healthy, woman who initially presented to the emergency department with abdominal pain. Grossly lipemic serum due to extremely high triglyceride (38.6 mmol/L) and cholesterol (23.2 mmol/L) levels were observed with a high blood glucose (23 mmol/L) and a low pH of 7.06 on a venous blood gas. She was treated successfully with fluids and insulin and had no sequale of pancreatitis or cerebral edema...
July 2017: Læknablađiđ
https://www.readbyqxmd.com/read/28815731/case-report-of-cutaneous-protothecosis-caused-by-prototheca-wickerhamii-designated-as-genotype-2-and-current-status-of-human-protothecosis-in-japan
#15
Maki Inoue, Azusa Miyashita, Hiromitsu Noguchi, Noriyuki Hirose, Kazuko Nishimura, Michiaki Masuda, Hironobu Ihn
An 85-year-old Japanese woman presented with infiltrative erythema and ulceration on the extensor surface of her right forearm. Direct microscopic examination demonstrated spherical and morula-like sporangia, while histopathology revealed numerous microorganisms with a mulberry-like appearance in the dermis. Staining of the microorganisms also showed mulberry-like sporangia that resembled the spokes of a wheel. The isolated yeast-like microorganism had been identified as Prototheca wickerhamii genotype 2 in another independent study on the basis of its morphological, biochemical and genetic analysis...
August 16, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28815123/rapid-and-reusable-text-visualization-and-exploration-development-with-delve
#16
Daniel R Harris, Ramakanth Kavuluru, Jerzy W Jaromczyk, Todd R Johnson
We present DELVE (Document ExpLoration and Visualization Engine), a framework for developing interactive visualizations as modular Web-applications to assist researchers with exploratory literature search. The goal for web-applications driven by DELVE is to better satisfy the information needs of researchers and to help explore and understand the state of research in scientific liter ature by providing immersive visualizations that both contain facets and are driven by facets derived from the literature. We base our framework on principles from user-centered design and human-computer interaction (HCI)...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28814897/discordance-of-the-estrogen-receptor-and-her-2-neu-in-breast-cancer-from-primary-lesion-to-first-and-second-metastatic-site
#17
Elyse E Lower, Shagufta Khan, Diane Kennedy, Robert P Baughman
BACKGROUND: Hormone receptor and HER-2/neu discordance between the primary lesion and first metastasis has been reported. This study was performed to determine further biomarker discordance rates between the first and subsequent metastatic breast cancer lesions. METHODS: We performed a retrospective review of paired biomarkers from primary breast cancers compared to first reported and subsequent metastases from 103 patients with breast cancer. The estrogen receptor (ER), progesterone receptor (PR), and HER-2/neu status were reported at all three time points...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/28814193/sirolimus-and-mirabegron-interaction-in-a-hematopoietic-cell-transplant-patient
#18
Jeff A Engle, Christina Fair
Purpose Hematopoietic cell transplant patients are exposed to numerous classes of medications. Transplant practitioners must vigilantly monitor for drug interactions especially involving immunosuppressants. We report a hematopoietic cell transplant patient receiving sirolimus who developed supratherapeutic serum concentrations after initiating mirabegron. Summary A 31-year-old, 98 kg female received a second umbilical cord blood transplant four years after the first transplant for relapsed acute myeloid leukemia...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/28813837/walking-speed-intention-model-using-soleus-electromyogram-signal-of-nondisabled-and-post-stroke-hemiparetic-patients
#19
Sang Hun Chung, Taejin Choi, Yoha Hwang, Hyungmin Kim, Seung-Jong Kim, Min Ho Chun, Jong Min Lee
It is well known that the activation of plantar flexors have a strong influence on the walking speed. If the gait speed can be predicted using this relationship, a post-stroke hemiparetic patient could control a gait rehabilitation robot according to his or her gait intention, and the robotic gait rehabilitation effect could be further improved. To find out this relationship, 9 nondisabled subjects and 4 chronic post-stroke hemiparetic subjects performed overground level walking at a comfortable pace, a slow pace, a fast pace, and an increasing pace with electromyogram sensors attached on plantar flexors...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28812940/odontogenic-orbital-abscess-with-intracranial-and-pulmonary-involvement
#20
E Hughes, N Wynne, S Quinn, T Fulcher
A 58-year-old woman presented to the emergency department with left ptosis and complete ophthalmoplegia. Imaging demonstrated a left orbital abscess. Her past medical history included cavitatory lung disease and "aseptic" meningitis 2 months previously. An anaerobic organism and commensal of the oral flora, Peptostreptococcus sp., was cultured from the orbital abscess. The patient was found to have a carious upper molar with chronic buccal abscess, which was extracted. This case presents an uncommon pathogen arising from an odontogenic infection as the etiology for orbital abscess, cavitatory lung disease, and meningitis in one patient...
August 16, 2017: Orbit
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