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Holter reference values

Stefan Sammito, Irina Böckelmann
BACKGROUND: The analysis of heart rate variability (HRV) has become an established procedure in recent decades. Because there are no appropriate reference values available, HRV findings can still only be compared within a group or in individuals in longitudinal studies. OBJECTIVE: The objectives of the present study were to examine a group of healthy subjects of different ages and sexes and to identify reference values for common HRV parameters. METHODS: Long-term 24-hour electrocardiograms of 695 voluntary subjects were recorded by using a 2-channel Holter system over a period of 24 hours during daily activities...
June 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Mathieu Courtheix, Zakaria Jalal, Pierre Bordachar, Xavier Iriart, Xavier Pillois, Cécile Escobedo, Catherine Rabot, Laetitia Tribout, Jean-Benoit Thambo
BACKGROUND: Syncopes are frequent in the paediatric population. Most are benign, but rare cases are caused by cardiac life-threatening diseases. Syncope units developed in the adult population have demonstrated improvement in evaluation and treatment, with a reduction in hospitalization. AIMS: We report our experience of paediatric syncope management in a dedicated unit, and analyse the value of different elements in the identification of cardiac causes. METHODS: This prospective study included 97 consecutive patients (mean age: 12...
March 2016: Archives of Cardiovascular Diseases
Olivier Bouchot, Charles Guenancia, Abdelkader Kahli, Charline Pujos, Ghislain Malapert, Catherine Vergely, Gabriel Laurent
OBJECTIVES: To assess the role of growth differentiation factor-15 (GDF-15) as a potential new predictor of postoperative atrial fibrillation (POAF) after off-pump (OFP) and on-pump (ONP) coronary artery bypass graft (CABG) surgery. DESIGN: Prospective, single-center, observational study. SETTING: University teaching hospital. PARTICIPANTS: The first 50 patients planned for OFP surgery and the first 50 patients planned for ONP surgery among patients referred for CABG with the following exclusion criteria: age<18 or>80 years, previous atrial fibrillation/flutter, previous treatment with amiodarone, previous cardiac surgery, and emergency surgery...
October 2015: Journal of Cardiothoracic and Vascular Anesthesia
B M Kaye, K Borgeat, P F Mõtsküla, V Luis Fuentes, D J Connolly
BACKGROUND: Tricuspid annular plane systolic excursion (TAPSE) is a useful estimate of right ventricular function in humans. Reference intervals for dogs have been generated, but the value of measuring TAPSE in other diseases, or investigating the association between TAPSE and outcome, is unknown. HYPOTHESIS: TAPSE is lower in Boxer dogs with ≥50 VPCs/24 h on Holter than in dogs with fewer ventricular ectopics, and lower TAPSE is associated with a shorter survival time...
March 2015: Journal of Veterinary Internal Medicine
Denise C Jarrin, Jennifer J McGrath, Paul Poirier, Louise Séguin, Richard E Tremblay, Jacques Y Montplaisir, Gilles Paradis, Jean R Séguin
Heart rate variability (HRV) is a non-invasive quantitative marker of cardiac autonomic function derived from continuous electrocardiogram (ECG) recordings. Normative HRV values and development factors have not been established in pediatric populations. The objective was to derive referent time- and frequency-domain HRV values for a population-based sample of children. Children aged 9-11 years (N = 1,036) participated in the Québec Longitudinal Study of Child Development cohort cardiovascular health screening...
January 2015: Pediatric Cardiology
Jenny Alenius Dahlqvist, Marcus Karlsson, Urban Wiklund, Rolf Hörnsten, Annika Rydberg
BACKGROUND: Our aim was to evaluate the intermittent use of a handheld ECG system for detecting silent arrhythmias and cardiac autonomic dysfunction in children with univentricular hearts. METHODS: Twenty-seven patients performed intermittent ECG recordings with handheld devices during a 14-day period. A manual arrhythmia analysis was performed. We analyzed heart rate variability (HRV) using scatter plots of all interbeat intervals (Poincaré plots) from the total observation period...
May 2014: Journal of Electrocardiology
Oscar Orihuela, María de Jesús Ventura, Marcela Ávila-Díaz, Alejandra Cisneros, Marlén Vicenté-Martínez, María-del-Carmen Furlong, Zuzel García-González, Diana Villanueva, Guadalupe Alcántara, Bengt Lindholm, Elvia García-López, Cleva Villanueva, Ramón Paniagua
UNLABELLED:INTRODUCTION: Spectral analysis of heart rate variability is a noninvasive method for evaluating autonomic cardiovascular dysfunction under various clinical conditions, such as in dialysis patients, in whom an imbalance between the sympathetic and parasympathetic nervous system appears to be an important risk factor for sudden cardiovascular death and arrhythmia. ♢ OBJECTIVE: We compared the effect of icodextrin-based dialysis solution, an option that allows for better metabolic and fluid overload control, with that of glucose-based dialysis fluid on sympathetic and parasympathetic activity in the heart, as assessed by heart rate variability, in diabetic patients on peritoneal dialysis (PD)...
January 2014: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
P J Holler, G Wess
BACKGROUND: E-point-to-septal-separation (EPSS) and the sphericity index (SI) are echocardiographic parameters that are recommended in the ESVC-DCM guidelines. However, SI cutoff values to diagnose dilated cardiomyopathy (DCM) have never been evaluated. OBJECTIVES: To establish reference ranges, calculate cutoff values, and assess the clinical value of SI and EPSS to diagnose DCM in Doberman Pinschers. ANIMALS: One hundred seventy-nine client-owned Doberman Pinschers...
January 2014: Journal of Veterinary Internal Medicine
Khaled M Said Othman, Shereen A Elshazly, Nihal M Heiba
BACKGROUND: The principal cause of mortality and morbidity in β-thalassemia major (β-TM) is the iron overload as these patients receive about 20 times the normal intake of iron, which leads to iron accumulation and damage in the liver, heart, and endocrine organs. Chronically transfused patients used to die from cardiac iron overload in their teens and twenties. Monitoring of iron status through cardiac magnetic resonance imaging (CMRI) has replaced the conventional methods of assessment, yet this modality is not readily available in centers where the disease distribution is maximal...
October 2014: Hematology (Amsterdam, Netherlands)
Marek Malik, Katerina Hnatkova, Donna Kowalski, James J Keirns, E Marcel van Gelderen
Data of a large clinical study were used to investigate how much are the QT/RR patterns in healthy subjects curved and whether these curvatures differ between women and men. Daytime drug-free 12-lead Holter recordings were repeated 4 times in each of 176 female healthy subjects and 176 male healthy subjects aged 32.7 ± 9.1 yr. In each of the subjects, up to 1,440 carefully verified QT interval measurements were obtained with QT/RR hysteresis-corrected RR intervals. Individual subject data were used to fit the following regression equation: QT = χ + (δ/γ)(1 - RR(γ)) + ε, where QT and RR are QT and RR measurements (in s), χ is regression intercept, δ is the QT/RR slope, γ is the QT/RR curvature and provides the lowest regression residual, and ε represents normally distributed zero-centered errors...
December 2013: American Journal of Physiology. Heart and Circulatory Physiology
Milind Y Desai, Aditya Bhonsale, Nicholas G Smedira, Peyman Naji, Maran Thamilarasan, Bruce W Lytle, Harry M Lever
BACKGROUND: We report the predictors of long-term outcomes of symptomatic hypertrophic cardiomyopathy patients undergoing surgical relief of left ventricular outflow tract obstruction. METHODS AND RESULTS: We studied 699 consecutive patients who have hypertrophic cardiomyopathy with severe symptomatic left ventricular outflow tract obstruction (47±11 years, 63% male) intractable to maximal medical therapy, who were referred to a tertiary hospital between January 1997 and December 2007 for the surgical relief of left ventricular outflow tract obstruction...
July 16, 2013: Circulation
Giovanni Quarta, Syed I Husain, Andrew S Flett, Daniel M Sado, Charles Y Chao, Marıá T Tomé Esteban, William J McKenna, Antonios Pantazis, James C Moon
BACKGROUND: Cardiovascular magnetic resonance (CMR) is commonly used in patients with suspected arrhythmogenic right ventricular cardiomyopathy (ARVC) based on ECG, echocardiogram and Holter. However, various diseases may present with clinical characteristics resembling ARVC causing diagnostic dilemmas. The aim of this study was to explore the role of CMR in the differential diagnosis of patients with suspected ARVC. METHODS: 657 CMR referrals suspicious for ARVC in a single tertiary referral centre were analysed...
2013: Journal of Cardiovascular Magnetic Resonance
A Noszczyk-Nowak
Heart rate turbulence (HRT) is modulated by the baroreceptor reflex and it was suggested that it could be used as a measure of autonomic dysfunction. Impaired HRT is of a significant prognostic value in humans after myocardial infarction, suffering from dilated cardiomyopathy and patients with heart failure. So far no studies were performed assessing the importance of HRT in dogs. The aim of this study was to prospectively evaluate the HRT turbulence onset (TO) and the turbulence slope (TS) in healthy dogs and in dogs with DCM and to compare the HRT in dogs with DCM that died during the first 30 days of observation and dogs with DCM that survived the first 30 days after the HRT analysis...
2012: Polish Journal of Veterinary Sciences
Maria Teresa La Rovere, Lidia Staszewsky, Simona Barlera, Roberto Maestri, Alessandro Mezzani, Paolo Midi, Roberto Marchioli, Aldo P Maggioni, Gianni Tognoni, Luigi Tavazzi, Roberto Latini
BACKGROUND: n-3 Polyunsaturated fatty acid (n-3PUFA) supplementation in the Gruppo Italiano per lo Studio della Sopravvivenza nell'Insufficienza Cardiaca (GISSI-HF) study reduced total mortality in patients with heart failure (HF), but the mechanism of action is still debated. The hypothesis of the present GISSI-HF substudy was that n-3PUFA may have beneficial effects on cardiac autonomic control. OBJECTIVE: To evaluate the effect of 1 g/day of n-3PUFA vs placebo on heart rate variability variables, deceleration capacity, and turbulence slope...
February 2013: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Josef Halamek, Jean-Philippe Couderc, Pavel Jurak, Vlastimil Vondra, Wojciech Zareba, Ivo Viscor, Pavel Leinveber
BACKGROUND: The patients with the long QT syndrome type-1 (LQT-1) have an impaired adaptation of the QT interval to heart rate changes. Yet, the description of the dynamic QT-RR coupling in genotyped LQT-1 has never been thoroughly investigated. METHOD: We propose a method to model the dynamic QT-RR coupling by defining a transfer function characterizing the relationship between a QT interval and its previous RR intervals measured from ambulatory Holter recordings...
October 2012: Annals of Noninvasive Electrocardiology
Thomas Buckley, Angela Stannard, Roger Bartrop, Sharon McKinley, Christopher Ward, Anastasia Susie Mihailidou, Marie-Christie Morel-Kopp, Monica Spinaze, Geoffrey Tofler
Early bereavement is associated with increased cardiovascular events. The mechanism, however, has not been well studied. We assessed whether bereavement is associated with an increased heart rate (HR) and decreased heart rate variability that might contribute to increased cardiovascular risk. A total of 78 bereaved spouses and parents (55 women and 23 men; aged 34 to 87 years, mean 65) were studied with 24-hour Holter monitoring within 2 weeks of bereavement (acute) and at 6 months. Their findings were compared to those from a nonbereaved reference group (52 women and 27 men) aged 33 to 91 years (mean 63...
November 1, 2012: American Journal of Cardiology
A Voss, A Heitmann, R Schroeder, A Peters, S Perz
Heart rate variability (HRV) analysis is an established method to characterize the autonomic regulation and is based mostly on 24h Holter recordings. The importance of short-term HRV (less than 30 min) for various applications is growing consistently. Major reasons for this are the suitability for ambulatory care and patient monitoring and the ability to provide an almost immediate test result. So far, there have been only a few studies that provided statistically relevant reference values for short-term HRV...
August 2012: Physiological Measurement
Shemaila Saleem, Muhammad Mazhar Hussain, Syed Muhammad Imran Majeed, Muhammad Alamgir Khan
OBJECTIVE: To identify the basic values of heart rate variability in Pakistani population and to verify our hypothesis that there are gender differences in cardiovascular autonomic modulation. METHODS: The descriptive cross sectional study based on convenience probability sampling was conducted at Armed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD) Pakistan. The duration of the study was from December 2009 to July 2010. It involved 24-hour holter monitoring of 45 healthy individuals using holter electrocardiography (ECG) recorder...
May 2012: JPMA. the Journal of the Pakistan Medical Association
Reiner Buchhorn, Christian Müller, Christian Willaschek, Kambiz Norozi
Background. Although stimulants have long been touted as treatments for attention deficit disorder with or without hyperactivity (ADHD), in recent years, increasing concerns have been raised about the cardiovascular safety of these medications. We aimed to prove if measurements of autonomic function with time domain analysis of heart rate variability (HRV) in 24-hour Holter ECG are useful to predict the risk of sudden cardiac death in ADHD children and adolescents. Methods. We analysed HRV obtained from children with the diagnosis of ADHD prior to (N = 12) or during medical therapy (N = 19) with methylphenidate (MPH), aged 10...
2012: ISRN Pharmacology
Christine S Zuern, Christian Eick, Konstantinos D Rizas, Cosmina Stoleriu, Petra Barthel, Christian Scherer, Karin A L Müller, Meinrad Gawaz, Axel Bauer
BACKGROUND: Severe autonomic failure (SAF) refers to combined abnormalities in reflex and tonic autonomic function. SAF indicates increased risk of death in post-infarction and heart failure patients, but has not been studied in aortic stenosis (AS). Here, we investigated SAF in patients with AS and tested its correlation with hemodynamic and biochemical markers. METHODS: We prospectively enrolled 174 patients with moderate to severe AS in sinus rhythm (age 76 ± 9 years; mean aortic valve area 0...
July 2012: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
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