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N J Kells, N J Beausoleil, C B Johnson, M A Sutherland, R S Morrison, W Roe
Tail docking of pigs is commonly performed to reduce the incidence of unwanted tail-biting behaviour. Two docking methods are commonly used: blunt trauma cutting (i.e. using side clippers), or cutting and concurrent cauterisation using a hot cautery iron. A potential consequence of tail amputation is the development of neuromas at the docking site. Neuromas have been linked to neuropathic pain, which can influence the longer-term welfare of affected individuals. To determine whether method of tail docking influences the extent of neuroma formation, 75 pigs were allocated to one of three treatments at birth: tail docked using clippers; tail docked using cautery iron; tail left intact...
December 1, 2016: Animal: An International Journal of Animal Bioscience
Miguel Pineda, Arthur L Burnett
INTRODUCTION: Inflatable penile prosthesis (IPP) surgery has been performed for more than 40 years. IPP infection rates have decreased owing to advances in manufacturing and surgical technique but have remained a devastating complication. AIMS: To describe the pathophysiology of infections, examine evidence associating clinical risk factors with IPP infection, assess the benefit of techniques aimed at preventing and managing infection, and discuss future directions...
October 2016: Sexual Medicine Reviews
Yue Ma, Xiaolong Sun, Wen Li, Yi Li, Tao Kang, Xiai Yang, Wen Jiang
BACKGROUND: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder in the central nervous system (CNS) with distinct clinical, radiological, and pathological features. The pathophysiology of CLIPPERS still remains unclear and the reports are quite few. Although the radiological lesions were reported to be located predominantly in the pons, brachium pontis, and cerebellum, other adjacent structures such as the white matter and spinal cord were very recently reported as involved regions in CLIPPERS...
November 2016: Medicine (Baltimore)
Masaaki Katayama
OBJECTIVE: To report appositional augmentation of Achilles tendon rupture in a toy breed dog with an intact flexor digitorum lateralis (FDL) muscle tendon. STUDY DESIGN: Clinical case report. ANIMALS: Two-year-old spayed female Toy Poodle with Achilles tendon rupture. METHODS: The Achilles tendon was accidentally ruptured by hair clippers during grooming. The dog demonstrated a plantigrade stance without digital flexion of the right hind limb...
October 6, 2016: Veterinary Surgery: VS
Todd J Kowalski, Shanu N Kothari, Michelle A Mathiason, Andrew J Borgert
BACKGROUND: Despite substantial prevention efforts, surgical site infections (SSIs) remain the most common health care-associated infection. It is unclear whether the Centers for Disease Control and Prevention recommendation to leave hair intact preoperatively reduces SSIs. STUDY DESIGN: A single-center, prospective, randomized, clinical trial was conducted from October 2009 to February 2015 in a 325-bed multispecialty, tertiary care teaching hospital to test the noninferiority of clipping hair to no hair removal in the prevention of SSIs...
April 23, 2016: Journal of the American College of Surgeons
Gilbert Siu, Don Vongviphut, Megha Mandalaywala
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Shinichi Kan
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) has been recently identified as an inflammatory central nervous system (CNS) disorder. Punctate and curvilinear gadolinium enhancement (peppering) the pons is a characteristic magnetic resonance imaging (MRI) feature of CLIPPERS. Pathogenesis of this disorder remains unknown. A specific serum or cerebrospinal fluid biomarker for this disorder is currently unknown. Whether CLIPPERS is an actual new disease or just represents overlapping symptoms from multiple diseases is still debated...
September 2016: Brain and Nerve, Shinkei Kenkyū No Shinpo
Richard K Zimmerman, G K Balasubramani, Mary Patricia Nowalk, Heather Eng, Leonard Urbanski, Michael L Jackson, Lisa A Jackson, Huong Q McLean, Edward A Belongia, Arnold S Monto, Ryan E Malosh, Manjusha Gaglani, Lydia Clipper, Brendan Flannery, Stephen R Wisniewski
BACKGROUND: The use of neuraminidase-inhibiting anti-viral medication to treat influenza is relatively infrequent. Rapid, cost-effective methods for diagnosing influenza are needed to enable appropriate prescribing. Multi-viral respiratory panels using reverse transcription polymerase chain reaction (PCR) assays to diagnose influenza are accurate but expensive and more time-consuming than low sensitivity rapid influenza tests. Influenza clinical decision algorithms are both rapid and inexpensive, but most are based on regression analyses that do not account for higher order interactions...
September 22, 2016: BMC Infectious Diseases
Xiaohe Hou, Xiaoke Wang, Bo Xie, Weihong Lin, Jun Liu, Dihui Ma, Hong-Liang Zhang
BACKGROUND: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a rare chronic inflammatory disorder in the central nervous system (CNS), which is characterized by magnetic resonance imaging (MRI) appearance with punctate and curvilinear gadolinium enhancement "peppering" the pons. Lesions of CLIPPERS mainly involve the pons and the cerebellum. Adjacent structures such as the medulla and the midbrain may also be involved. It is proposed that CLIPPERS is an immune-mediated inflammatory condition characteristic of T-cell-predominant infiltrates and good responsiveness to corticosteroids...
August 2016: Medicine (Baltimore)
Camilla Beate Hill, Andrew Cassin, Gabriel Keeble-Gagnère, Monika S Doblin, Antony Bacic, Ute Roessner
Plant roots are the first organs sensing and responding to salinity stress, manifested differentially between different root types, and also at the individual tissue and cellular level. High genetic diversity and the current lack of an assembled map-based sequence of the barley genome severely limit barley research potential. We used over 580 and 600 million paired-end reads, respectively, to create two de novo assemblies of a barley landrace (Sahara) and a malting cultivar (Clipper) with known contrasting responses to salinity...
2016: Scientific Reports
Benjamin Ley, Edward Silverman, Kara Peery, Delfina Dominguez
Nosocomial infections are a concern of growing interest in veterinary medicine. Clipper blades have been confirmed as fomites for numerous potential pathogens and, as such, may be associated with wound and surgical site infections. The goal of this study was to evaluate the disinfectant capabilities of several commonly used clipper blade cleaning products. Seventy sterile clipper blades were inoculated with strains of Pseudomonas aeruginosa , Escherichia coli , and Staphylococcus aureus . Blades were then subjected to one of seven treatment groups for disinfecting...
September 2016: Journal of the American Animal Hospital Association
Anjana Ray, Breanne Mordorski, Angelo Landriscina, Jamie Rosen, Joshua Nosanchuk, Adam Friedman
Shaving is an ubiquitous practice, and cutaneous irritation and inflammation are common sequelae, which may be worsened by underlying skin conditions or poor hair removal techniques. Moisturizing shaving creams and aftershaves are available to help maintain or restore the epidermal barrier; however, many continue to suffer from post-shave redness, itching, and pain. To reduce post-shave inflammation, some products have included botanical and other natural ingredients, which are often favored by consumers. We evaluated Bensal HP, an ointment containing 3% oak bark extract, 3% salicylic acid, and 6% benzoic acid, which has documented anti-inflammatory and antimicrobial properties, in a murine model of shave irritation to determine whether it would be useful in this clinical setting...
July 1, 2016: Journal of Drugs in Dermatology: JDD
Charles E Edmiston, Russell K Griggs, Judith Tanner, Maureen Spencer, Gary R Seabrook, David Leaper
BACKGROUND: Perioperative hair removal using clippers requires lengthy cleanup to remove loose hairs contaminating the operative field. We compared the amount of hair debris and associated microbiologic contamination produced during clipping of surgical sites using standard surgical clippers (SSC) or clippers fitted with a vacuum-assisted hair collection device (SCVAD). METHODS: Trained nurses conducted bilateral hair clipping of the chest and groin of 18 male subjects using SSC or SCVAD...
December 1, 2016: American Journal of Infection Control
Guillaume Taieb, Pierre Labauge, Mei-Ping Ding, Yin-Xi Zhang, Hai-Tao Hu, Xiao-Yan Ding, Lin-Hui Chen, Ye Du, Chun-Hong Shen, Yi Guo
No abstract text is available yet for this article.
June 7, 2016: Neurology
Larrie D Ferreiro, Alexander Pollara
Ship hydrodynamics in the nineteenth century was dominated by John Scott Russell's wave-line theory. Russell, a prominent British shipbuilder and scientist, argued that wavemaking was the primary source of resistance for ships, and that by designing ships according to trigonometric curves and proportions (the wave line) this resistance could effectively be eliminated. From the 1840s to the 1880s, shipbuilders such as John Willis Griffiths, Donald McKay and George Steers designed their clipper ships (like Sea Witch and Flying Cloud) and yachts (America) with wave-line hulls, while authors like Jules Verne referenced Russell's theory...
April 2016: Technology and Culture
Morten Blaabjerg, Klemens Ruprecht, Tim Sinnecker, Daniel Kondziella, Thoralf Niendorf, Bjørg Morell Kerrn-Jespersen, Mette Lindelof, Hans Lassmann, Bjarne Winther Kristensen, Friedemann Paul, Zsolt Illes
OBJECTIVE: To examine if there is widespread inflammation in the brain of patients with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome by using histology and ultra-high-field MRI at 7.0T. METHODS: We performed a detailed neuropathologic examination in 4 cases, including 1 autopsy case, and studied 2 additional patients by MRI at 7.0T to examine (1) extension of inflammation to areas appearing normal on 3...
June 2016: Neurology® Neuroimmunology & Neuroinflammation
Rovaina L Doyle, Raqueli T França, Camila B Oliveira, João F P Rezer, Guilherme M Klafke, João R Martins, Andrea P Santos, Naíla C do Nascimento, Joanne B Mesick, Sonia T A Lopes, Daniela B R Leal, Aleksandro S Da Silva, Cinthia M Andrade
Bovine anaplasmosis is caused by the obligate intraerythrocytic bacteria Anaplasma marginale. These bacteria are transmitted by tick species such as Rhipicephalus (Boophilus) microplus, blood-sucking insects, and fomites (needles, clippers, and other blood contaminated equipment). During the acute phase of infection, animals may develop fever, anemia, jaundice, and hepatosplenomegaly. The aims of this study are to quantify the bacteremia by quantitative PCR in eight naïve calves experimentally infected by A...
June 2016: Microbial Pathogenesis
M T Zacher, A M Högele, M Hanschen, F von Matthey, A-K Beer, F Gebhardt, P Biberthaler, K-G Kanz
Wound management is one of the major tasks in emergency departments. The surrounding intact skin but not the wound itself should be disinfected before starting definitive wound treatment. Hair should first be removed by clipping to 1-2 mm above the skin with scissors or clippers as shaving the area with a razor damages the hair follicles and increases the risk of wound infections. Administration of local anesthetics should be performed directly through the exposed edges of the wound. After wound examination, irrigation is performed with Ringer's solution, normal saline or distilled water...
April 2016: Der Anaesthesist
Megan C Shelden, Daniel A Dias, Nirupama S Jayasinghe, Antony Bacic, Ute Roessner
Barley (Hordeum vulgare L.) is the most salt-tolerant cereal crop and has excellent genetic and genomic resources. It is therefore a good model to study salt-tolerance mechanisms in cereals. We aimed to determine metabolic differences between a cultivated barley, Clipper (tolerant), and a North African landrace, Sahara (susceptible), previously shown to have contrasting root growth phenotypes in response to the early phase of salinity stress. GC-MS was used to determine spatial changes in primary metabolites in barley roots in response to salt stress, by profiling three different regions of the root: root cap/cell division zone (R1), elongation zone (R2), and maturation zone (R3)...
June 2016: Journal of Experimental Botany
Tamas Constantin, Ivan Foeldvari, Jelena Vojinovic, Gerd Horneff, Ruben Burgos-Vargas, Irina Nikishina, Jonathan D Akikusa, Tadej Avcin, Jeffrey Chaitow, Elena Koskova, Bernard R Lauwerys, Inmaculada Calvo Penades, Berit Flato, Maria Luz Gamir, Hans-Iko Huppertz, Juan Jose Jaller Raad, Katerina Jarosova, Jordi Anton, Marie Macku, William J Otero Escalante, Lidia Rutkowska-Sak, Ralf Trauzeddel, Patricia J Velez-Sanchez, Carine Wouters, Joseph Wajdula, Chuanbo Zang, Jack Bukowski, Deborah Woodworth, Bonnie Vlahos, Alberto Martini, Nicolino Ruperto
OBJECTIVE: The main objective was to determine the 2-year clinical benefit and safety of etanercept (ETN) in children with the juvenile idiopathic arthritis (JIA) categories of extended oligoarthritis (eoJIA), enthesitis-related arthritis (ERA), or psoriatic arthritis (PsA). METHODS: CLIPPER was a 96-week, phase IIIb, open-label, multicenter study. Patients with eoJIA, ERA, or PsA received ETN 0.8 mg/kg once weekly (50 mg max) for up to 96 weeks. The proportions of patients reaching the JIA American College of Rheumatology (ACR) 30/50/70/90/100 and inactive disease responses at Week 96 were calculated...
April 2016: Journal of Rheumatology
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