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https://www.readbyqxmd.com/read/29652210/idiopathic-central-nervous-system-inflammatory-disease-in-the-setting-of-hla-b27-uveitis
#1
Eric L Crowell, Margaret L Pfeiffer, Ankur A Kamdar, Mary K Koenig, Susan E Wittenberg, Emilio P Supsupin, Ore-Ofe O Adesina
PURPOSE: The purpose of the article is to describe a novel case of idiopathic central nervous system inflammatory disease with bilateral human leukocyte antigen (HLA)-B27-positive anterior uveitis. METHODS/RESULTS: A 15-year-old African American boy with bilateral HLA-B27-positive anterior uveitis controlled with topical and oral steroids for 8 months acutely developed headaches, left eyelid ptosis, and binocular diplopia. Imaging showed lesions in the right midbrain, superior colliculus, cerebellar peduncles, and cerebellar vermis and leptomeningeal enhancement along the vermian foliae...
April 13, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29629677/blood-and-virus-detection-on-barber-clippers
#2
Z Spengane, S Korsman, K Mkentane, L M Davids, W Zemanay, M Africa, S Mbhele, M Nicol, F Gumedze, D Ngwanya, N P Khumalo
BACKGROUND: Bleeding from the popular clean-shave 'chiskop' haircut was recently reported as prevalent in South Africa (SA), a country with 6.9 million HIV-infected people. OBJECTIVES: To investigate the prevalence of barber hair clipper contamination with blood and HIV and hepatitis B viruses. METHODS: Fifty barbers from three townships in Cape Town, SA, were invited to participate. One clipper from each barber was collected immediately after it had been used for a clean-shave haircut...
March 28, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29569627/-selected-risk-factors-for-occupational-exposures-to-blood-borne-pathogens-in-cosmetics-salons
#3
Maria Gańczak, Marta Paczewska, Zbigniew Szych, Katarzyna Topczewska, Marzna Drozd-Dąbrowska
BACKGROUND: Services offered in the esthetic/beauty industry poses the risk of blood-borne infections (BBIs) due to carrying out invasive procedures. The study objective: was to assess the number of sharps injuries, occupational risk factors, and preventive methods used among cosmetologists. MATERIAL AND METHODS: The anonymous survey was conducted (February-April 2017) in randomly selected beauty/esthetic medicine clinics in Szczecin, Poland; 96 cosmetologists were invited...
March 22, 2018: Medycyna Pracy
https://www.readbyqxmd.com/read/29511706/effective-treatment-of-clippers-with-long-term-use-of-rituximab
#4
Veronica P Cipriani, Nancy Arndt, Peter Pytel, Anthony T Reder, Adil Javed
No abstract text is available yet for this article.
May 2018: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/29414291/a-cerebral-phenotype-of-chronic-lymphocytic-inflammation-with-pontine-perivascular-enhancement-responsive-to-steroids-a-case-report-and-review-of-the-literature
#5
Sho Okune, Kazuhiro Ishii, Shogo Ouchi, Kazuki Sakakura, Masahide Matsuda, Akira Tamaoka
CLIPPERS (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) is an inflammatory central nervous system disorder that gives rise to brainstem symptoms such as diplopia and articulatory disorders. It shows characteristic "salt-and-pepper" enhancing brainstem lesions on magnetic resonance imaging (MRI) scans. We present an unusual case of CLIPPERS, in which a 29-year-old man initially presented with a seizure. Brain MRI revealed faint open-ring enhancements in the right frontal lobe, and a brain biopsy was performed to make a definitive diagnosis...
January 26, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29370226/a-critical-comparison-of-topology-based-pathway-analysis-methods
#6
Ivana Ihnatova, Vlad Popovici, Eva Budinska
One of the aims of high-throughput gene/protein profiling experiments is the identification of biological processes altered between two or more conditions. Pathway analysis is an umbrella term for a multitude of computational approaches used for this purpose. While in the beginning pathway analysis relied on enrichment-based approaches, a newer generation of methods is now available, exploiting pathway topologies in addition to gene/protein expression levels. However, little effort has been invested in their critical assessment with respect to their performance in different experimental setups...
2018: PloS One
https://www.readbyqxmd.com/read/29344100/surgical-site-infection-prevention-an-analysis-of-compliance-with-good-practice-in-a-teaching-hospital
#7
Adriana Cristina de Oliveira, Camila Sarmento Gama
Background: Surgical teams play a critical role in reducing surgery-related risks during preoperative and intraoperative phases. Aim: To analyse the preoperative and intraoperative practices adopted by surgical teams in surgical site infections prevention. Methods: This was a cross-sectional study conducted during April-September 2013 in a large university hospital in Belo Horizonte, Minas Gerais, Brazil. It was conducted through observation of the surgical practice during preoperative and intraoperative phases of procedures used by a gastroenterological, cardiovascular and paediatric surgical team...
November 2017: Journal of Infection Prevention
https://www.readbyqxmd.com/read/29193048/occipital-headache-in-chronic-lymphocytic-inflammation-with-pontine-perivascular-enhancement-responsive-to-steroids-clippers
#8
Christian Cordano, Giselle Y López, Andrew W Bollen, Bardia Nourbakhsh
No abstract text is available yet for this article.
March 2018: Headache
https://www.readbyqxmd.com/read/29161360/reply-clippers-a-possible-symptomatic-lymphohistiocytic-immune-reaction
#9
W Oliver Tobin, Yong Guo, B Mark Keegan
No abstract text is available yet for this article.
January 1, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29161338/clippers-a-possible-symptomatic-lymphohistiocytic-immune-reaction
#10
Guillaume Taieb, Pierre Labauge
No abstract text is available yet for this article.
January 1, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29096034/cns-erdheim-chester-disease-a-challenge-to-diagnose
#11
REVIEW
Zenggang Pan, Bette K Kleinschmidt-DeMasters
Erdheim-Chester disease (ECD) is a rare nonLangerhans cell histiocytosis. Although approximately 50% of cases eventually involve the central nervous system (CNS), the CNS has seldom been reported as the initial biopsy site. The diagnosis of CNS ECD can be challenging due to morphologic overlap with reactive histiocytic proliferation, Langerhans cell histiocytosis (LCH), and extranodal Rosai-Dorfman disease (RDD). We present 3 cases from our files that illustrate the protean manifestations of ECD. Case 1 was a 47-year-old man with ataxia, dysarthria, and intermittent ophthalmoplegia whose cerebellar biopsy had shown only profuse, nonspecific Rosenthal fiber-rich piloid gliosis; ECD was diagnosed only at autopsy...
December 1, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/29062327/risk-factors-associated-with-acquiring-superficial-fungal-infections-in-school-children-in-south-western-nigeria-a-comparative-study
#12
COMPARATIVE STUDY
Olaide Oke Olutoyin, Olaniyi Onayemi, Akinlolu Omisore Gabriel
INTRODUCTION: Superficial fungal infections (SFI) are caused mainly by dermatophytes and yeasts. SFI is of major public health concern and is a common cause of skin disease among school children. OBJECTIVES: The aim of this study was to identify the risk factors associated with acquiring superficial fungal infections in school children in Ile-Ife, South West Nigeria as this will assist in instituting appropriate interventions. METHODS: A total of 560 children; 280 with superficial fungal infections as subjects and 280 age and sex matched school children as controls were recruited through multistage sampling method from 10 primary schools (private and public owned) in Ile-Ife, Nigeria...
June 2017: African Health Sciences
https://www.readbyqxmd.com/read/29055484/chronic-lymphocytic-inflammation-with-pontine-perivascular-enhancement-responsive-to-steroids-clippers-a-pediatric-case-report-with-six-year-follow-up
#13
Aravindhan Veerapandiyan, Amit Chaudhari, Prabhav Deo, Xue Ming
BACKGROUND: Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder involving brainstem, pons in particular, characterized by a predominant T-cell pathology and responsiveness to glucocorticosteroids. We describe a difficult 6 year course of this rare syndrome in a 10-year-old girl. CASE REPORT: Our patient presented with diplopia, spastic paraparesis, and unsteady gait. MRI showed characteristic punctate hyper-intensities with enhancement in the brain stem, cerebellar peduncles, and optic chiasm and diffuse nodular enhancement throughout the cervical and thoracic spinal cord...
October 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29050399/diagnostic-criteria-for-chronic-lymphocytic-inflammation-with-pontine-perivascular-enhancement-responsive-to-steroids-clippers
#14
W Oliver Tobin, Yong Guo, Karl N Krecke, Joseph E Parisi, Claudia F Lucchinetti, Sean J Pittock, Jay Mandrekar, Divyanshu Dubey, Jan Debruyne, B Mark Keegan
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a central nervous system inflammatory syndrome predominantly affecting the brainstem, cerebellum, and spinal cord. Following its initial description, the salient features of CLIPPERS have been confirmed and expanded upon, but the lack of formalized diagnostic criteria has led to reports of patients with dissimilar features purported to have CLIPPERS. We evaluated clinical, radiological and pathological features of patients referred for suspected CLIPPERS and propose diagnostic criteria to discriminate CLIPPERS from non-CLIPPERS aetiologies...
September 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29037798/electroencephalographic-assessment-of-oral-meloxicam-topical-anaesthetic-cream-and-cautery-iron-for-mitigating-acute-pain-in-pigs-sus-scrofa-undergoing-tail-docking
#15
Nikki J Kells, N J Beausoleil, M A Sutherland, R M Morrison, Craig B Johnson
OBJECTIVE: To evaluate the efficacy of oral meloxicam, topical anaesthetic cream and cautery iron in mitigating acute nociceptive responses of pigs to tail docking. STUDY DESIGN: A prospective, randomized, controlled experimental study. ANIMALS: A total of 40 healthy Large WhitexLandrace pigs aged 21±1 days, weighing 6.1±0.9 kg. METHODS: Pigs were randomly assigned to one of four treatments (n=10 per treatment): CONTROL: docked using clippers without analgesia; MEL: docked using clippers after administration of oral meloxicam; EMLA: docked using clippers after application of topical anaesthetic cream; and CAUT: docked using a cautery iron without analgesia...
September 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29019413/instrumentation-for-testing-whether-the-icy-moons-of-the-gas-and-ice-giants-are-inhabited
#16
Julian Chela-Flores
Evidence of life beyond Earth may be closer than we think, given that the forthcoming missions to the jovian system will be equipped with instruments capable of probing Europa's icy surface for possible biosignatures, including chemical biomarkers, despite the strong radiation environment. Geochemical biomarkers may also exist beyond Europa on icy moons of the gas giants. Sulfur is proposed as a reliable geochemical biomarker for approved and forthcoming missions to the outer solar system. Key Words: JUICE mission-Clipper mission-Geochemical biomarkers-Europa-Moons of the ice giants-Geochemistry-Mass spectrometry...
October 2017: Astrobiology
https://www.readbyqxmd.com/read/28987176/immune-mediated-disorders
#17
Romana Höftberger, Hans Lassmann
Paraneoplastic and autoimmune encephalitis comprise a group of immune-mediated disorders that are associated with different immune effector mechanisms. Classic paraneoplastic neurologic syndromes are triggered by an antitumor immune response. The disease is considered to result from a T-cell response; in addition, patients harbour high titers of autoantibodies against intracellular antigens that are considered as epiphenomenon but are useful diagnostic markers. Neuropathology consists of T-cell-dominated inflammation, marked neuronal loss, and microglial activation with upregulation of HLA-DR...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28922240/an-efficient-method-for-hair-containment-during-head-and-neck-surgery
#18
Nicola Zingaretti, Fabrizio De Biasio, Michele Riccio, Andrea Marchesi, Pier Camillo Parodi
The authors present a simple technique for operations around hair-bearing areas such as during a rhytidectomy. Hair surrounding the surgical field is twisted into bundles and clipped with duckbill clips. The authors repeat the procedure for each strand of hair. Between 5 and 7 duckbill clips may be required per surgery.The clippers are faster, easily applicable, and well performing. They can be used with different hair lengths, and they do not require any additional trimming or shaving; clips also keep the hair firmly in place, and they do not loosen up in the process...
November 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28919125/multi-institution-analysis-of-infection-control-practices-identifies-the-subset-associated-with-best-surgical-site-infection-performance-a-texas-alliance-for-surgical-quality-collaborative-project
#19
Catherine H Davis, Lillian S Kao, Jason B Fleming, Thomas A Aloia
BACKGROUND: In an effort to reduce surgical site infection (SSI) rates, a large number of infection control practices (ICPs), including operating room attire policies, have been recommended. However, few have proven benefits and many are costly, time-consuming, and detrimental to provider morale. The goal of this multi-institution study was to determine which ICPs are associated with lower postoperative SSI rates. STUDY DESIGN: Twenty American College of Surgeons NSQIP and Texas Alliance for Surgical Quality-affiliated hospitals completed this Quality Improvement Assessment Board-approved study...
August 16, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28901669/automating-tasks-in-protein-structure-determination-with-the-clipper-python-module
#20
Stuart McNicholas, Tristan Croll, Tom Burnley, Colin M Palmer, Soon Wen Hoh, Huw T Jenkins, Eleanor Dodson, Kevin Cowtan, Jon Agirre
Scripting programming languages provide the fastest means of prototyping complex functionality. Those with a syntax and grammar resembling human language also greatly enhance the maintainability of the produced source code. Furthermore, the combination of a powerful, machine-independent scripting language with binary libraries tailored for each computer architecture allows programs to break free from the tight boundaries of efficiency traditionally associated with scripts. In the present work, we describe how an efficient C++ crystallographic library such as Clipper can be wrapped, adapted and generalized for use in both crystallographic and electron cryo-microscopy applications, scripted with the Python language...
January 2018: Protein Science: a Publication of the Protein Society
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