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https://www.readbyqxmd.com/read/28800890/creating-a-lung-adenocarcinoma-canvas-one-brush-stroke-at-a-time
#1
EDITORIAL
Sai Yendamuri
No abstract text is available yet for this article.
July 22, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28781373/diabetes-mellitus-cardiovascular-and-renal-benefits-of-sglt2-inhibition-insights-from-canvas
#2
Volker Vallon, Scott C Thomson
No abstract text is available yet for this article.
August 7, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28776709/allergic-contact-dermatitis-caused-by-dimethylthiocarbamylbenzothiazole-sulfide-dmtbs-in-canvas-shoes-in-search-of-the-culprit-allergen
#3
Marie L Schuttelaar, Joost M Meijer, Malin Engfeldt, Hilde Lapeere, An Goossens, Magnus Bruze, Christina Persson, Ola Bergendorff
BACKGROUND: During rubber vulcanization, new compounds can be formed. OBJECTIVES: To report a case of allergic shoe dermatitis in which the search for the allergen ultimately led to the identification of dimethylthiocarbamylbenzothiazole sulfide (DMTBS). METHODS: A female presented with eczema on her feet after wearing Sperry Top Sider® canvas sneakers. Patch testing was performed with the European baseline series, additional series, shoe materials, and extracts of shoe materials...
August 4, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28763045/mzstudio-a-dynamic-digital-canvas-for-user-driven-interrogation-of-mass-spectrometry-data
#4
Scott B Ficarro, William M Alexander, Jarrod A Marto
Although not yet truly 'comprehensive', modern mass spectrometry-based experiments can generate quantitative data for a meaningful fraction of the human proteome. Importantly for large-scale protein expression analysis, robust data pipelines are in place for identification of un-modified peptide sequences and aggregation of these data to protein-level quantification. However, interoperable software tools that enable scientists to computationally explore and document novel hypotheses for peptide sequence, modification status, or fragmentation behavior are not well-developed...
August 1, 2017: Proteomes
https://www.readbyqxmd.com/read/28745596/putting-lgbtq-people-back-on-the-canvas-of-history
#5
Owen Jones
No abstract text is available yet for this article.
July 22, 2017: Lancet
https://www.readbyqxmd.com/read/28742644/update-on-sglt2-inhibitors-new-data-released-at-the-american-diabetes-association
#6
Sara Lee
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are one of the newer classes of antiglycemic agents approved for the management of patients with type 2 diabetes mellitus. Due to their unique mechanism of action, SGLT2 inhibitors have shown to be beneficial beyond glucose control. The improvement in cardiovascular (CV) outcomes was first observed in the landmark EMPA-REG OUTCOMES study. Following these results, numerous CV outcome trials were designed to identify whether the beneficial CV and renal effects observed with empagliflozin are unique or a drug class effect...
September 2017: Critical Pathways in Cardiology
https://www.readbyqxmd.com/read/28734269/crime-scene-reconstruction-sex-prediction-from-blood-stained-foot-sole-impressions
#7
Nabanita Basu, Samir Kumar Bandyopadhyay
It is often difficult to predict the sex of an individual based on bloody incomplete footprints. However, such prints/impressions are particularly common in a crime scene. Again variability in the texture, color of the target surface has an impact on the bloodstained impression formed. The study of bare foot, footprint, footwear (i.e. shoe, canvas etc.) within the legal context is referred to as forensic podiatry. Based on the fact that it is possible to predict the sex of an individual from footprint impressions, an automated model has been proposed in this paper for analyzing the sex of an individual from his/her broken/incomplete footprint impressions based on morphological features alone...
June 26, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28726326/speechless
#8
Nadine T Himelfarb
Bright blue eyes rimmed with deep sun wrinkles, a crown of mousy brown hair that appeared freshly cut by a four-year old with safety scissors, the patient was thin figured, wearing a flannel, yellowed t-shirt peaking from underneath, and a boxy, heavily stained canvas jacket over the shoulders. Old jeans were cinched at the waist by a crackled leather belt. The dirty right foot which lay bare on the stretcher was then thrust at me. The patient pointed angrily at the exposed foot. This article is protected by copyright...
July 20, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28708611/upflow-anaerobic-sludge-blanket-and-aerated-constructed-wetlands-for-swine-wastewater-treatment-a-pilot-study
#9
F Masi, A Rizzo, N Martinuzzi, S D Wallace, D Van Oirschot, P Salazzari, E Meers, R Bresciani
Swine wastewater management is often affected by two main issues: a too high volume for optimal reuse as a fertilizer and a too high strength for an economically sustainable treatment by classical solutions. Hence, an innovative scheme has been tested to treat swine wastewater, combining a low cost anaerobic reactor, upflow anaerobic sludge blanket (UASB), with intensified constructed wetlands (aerated CWs) in a pilot scale experimental study. The swine wastewater described in this paper is produced by a swine production facility situated in North Italy...
July 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28699762/coloring-by-number-core-outcome-measures-and-the-canvas-of-icu-survivorship
#10
Bronwen Connolly, Catherine L Hough
No abstract text is available yet for this article.
July 12, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28688195/physiology-of-biodeterioration-on-canvas-paintings
#11
REVIEW
Fernando Poyatos, Fátima Morales, A W Nicholson, Antonio Giordano
The study of the physiological action of microorganisms in artistic materials is one of the most interesting topics in biodeterioration nowadays. Pathologies and illnesses of organic and inorganic materials provoked by microorganisms can be treated by experts by a variety of preventive interventions. Artistic medicine encompasses the monitoring of the exhibition and storage of art, as well as proper environmental conditions and the regular cleaning of museums. Biodeterioration control is essential in order to prevent fungal and bacterial contamination in artwork...
July 8, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28656725/diabetes-news
#12
Payal H Marathe, Abigail E Dove, Kelly L Close
More than 16,000 people gathered in San Diego, CA, USA for the 77th annual Scientific Sessions of the American Diabetes Association (ADA). One of the most highly-anticipated sessions of the meeting was a presentation of integrated results from the Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes (CANVAS and CANVAS-R) trials.(1) The program studied a total of 10,142 people across two trials.
June 28, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28650952/novel-patient-positioning-apparatus-for-retinal-surgery-in-a-case-of-severe-kyphosis
#13
Douglas S M Iaboni, Mark E Seamone, Mary S Stairs, Daniel M OʼBrien, M Sheldon Bisson, R Rishi Gupta
PURPOSE: To describe a novel patient positioning apparatus for intraocular surgery capable of accommodating patients with thoracic kyphosis. METHODS: Case report. RESULTS: A 60-year-old man presented with a macula-off retinal detachment and severe ankylosing spondylitis. The patient was scheduled for combined pars plana vitrectomy and scleral buckle. Because of the patient's severe kyphosis, a custom-designed positioning apparatus was built...
June 23, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28605608/canagliflozin-and-cardiovascular-and-renal-events-in-type-2-diabetes
#14
Bruce Neal, Vlado Perkovic, Kenneth W Mahaffey, Dick de Zeeuw, Greg Fulcher, Ngozi Erondu, Wayne Shaw, Gordon Law, Mehul Desai, David R Matthews
Background Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that reduces glycemia as well as blood pressure, body weight, and albuminuria in people with diabetes. We report the effects of treatment with canagliflozin on cardiovascular, renal, and safety outcomes. Methods The CANVAS Program integrated data from two trials involving a total of 10,142 participants with type 2 diabetes and high cardiovascular risk. Participants in each trial were randomly assigned to receive canagliflozin or placebo and were followed for a mean of 188...
June 12, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28525772/implementation-of-glycanbuilder-to-draw-a-wide-variety-of-ambiguous-glycans
#15
Shinichiro Tsuchiya, Nobuyuki P Aoki, Daisuke Shinmachi, Masaaki Matsubara, Issaku Yamada, Kiyoko F Aoki-Kinoshita, Hisashi Narimatsu
GlyTouCan version 1.0 was released in 2015 as the international glycan structure repository, and a new sequence format called WURCS (Web3 Unique Representation of Carbohydrate Structures) was proposed during the early stages of the GlyTouCan project. GlyTouCan uses WURCS as its base representation for glycans because existing formats were insufficient in their flexibility to represent any and all glycans universally. Therefore, in order to obtain WURCS strings for existing or new glycan structures, conversion tools or glycan structure editors that can export WURCS became necessary...
April 19, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28504939/correlation-preserving-photo-collage
#16
Lingjie Liu, Hongjie Zhang, Guangmei Jing, Yanwen Guo, Zhonggui Chen, Wenping Wang
A new method is presented for producing photo collages that preserve content correlation of photos. We use deep learning techniques to find correlation among given photos to facilitate their embedding on the canvas, and develop an efficient combinatorial optimization technique to make correlated photos stay close to each other. To make efficient use of canvas space, our method first extracts salient regions of photos and packs only these salient regions. We allow the salient regions to have arbitrary shapes, therefore yielding informative, yet more compact collages than by other similar collage methods based on salient regions...
May 12, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28459138/main-drivers-of-outcome-differ-between-short-and-long-term-in-severe-alcoholic-hepatitis-a-prospective-study
#17
Alexandre Louvet, Julien Labreuche, Florent Artru, Alexis Bouthors, Benjamin Rolland, Pierre Saffers, Julien Lollivier, Elise Lemaître, Sébastien Dharancy, Guillaume Lassailly, Valérie Canva-Delcambre, Alain Duhamel, Philippe Mathurin
Understanding the mechanisms of outcome according to the time frame can help optimize the therapeutic development in severe alcoholic hepatitis (AH). OBJECTIVE: to assess short-term and long-term survival in severe AH based on baseline disease severity, extent of therapeutic improvement, long-term influence of alcohol relapse and their interaction. DESIGN: Data and alcohol consumption were prospectively recorded in 398 patients treated with corticosteroids at short (from corticosteroid initiation to 6 months) and long term (from 6 months to maximum follow-up time)...
April 29, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28451689/a-randomized-trial-comparing-classical-participatory-design-to-vandaid-an-interactive-crowdsourcing-platform-to-facilitate-user-centered-design
#18
Kevin R Dufendach, Sabine Koch, Kim M Unertl, Christoph U Lehmann
BACKGROUND: Early involvement of stakeholders in the design of medical software is particularly important due to the need to incorporate complex knowledge and actions associated with clinical work. Standard user-centered design methods include focus groups and participatory design sessions with individual stakeholders, which generally limit user involvement to a small number of individuals due to the significant time investments from designers and end users. OBJECTIVES: The goal of this project was to reduce the effort for end users to participate in co-design of a software user interface by developing an interactive web-based crowdsourcing platform...
April 28, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28450142/pan-genome-analysis-of-clostridium-botulinum-reveals-unique-targets-for-drug-development
#19
Tulika Bhardwaj, Pallavi Somvanshi
Clostridium botulinum, a formidable pathogen is responsible for the emerging cause of food poisoning cases on the global canvas. The endemicity of bacterium Clostridium botulinum is reflected by the sudden hospital outbreaks and increased resistance towards multiple drugs. Therefore, a combined approach of in-silico comparative genomic analysis with statistical analysis was applied to overcome the limitation of bench-top technologies. Owing to the paucity of genomic data available by the advent of third generation sequencing technologies, several 'omics' technologies were applied to understand the underlying evolutionary pattern and lifestyle of the bacterial pathogen using phylogenomics...
August 5, 2017: Gene
https://www.readbyqxmd.com/read/28436307/choice-of-anesthesia-for-endovascular-treatment-of-acute-ischemic-stroke-protocol-for-a-randomized-controlled-canvas-trial
#20
Yuming Peng, Yan Li, Minyu Jian, Xiaoyuan Liu, Jian Sun, Bo Jia, Jia Dong, Min Zeng, Nan Lin, Li Zhang, Adrian W Gelb, Matthew Tv Chan, Ruquan Han
Background Observational studies indicate that the type of anesthesia, local or general, may be associated with the post-procedural neurological function in patients with acute ischemic stroke undergoing endovascular treatment. However, these results need further confirmation, and the causal relationship has not yet been established. Methods This is a randomized controlled equivalence trial. Permuted block randomization stratified by culprit vessels will be used. Six hundred and forty patients with acute ischemic stroke undergoing endovascular recanalization will be randomized one to one to receive either general anesthesia or local anesthesia...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
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