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https://www.readbyqxmd.com/read/29103247/susac-syndrome-a-rare-cause-of-a-confusional-state
#1
Chen Ben David, Kassem Sharif, Abdulla Watad, Nicola Luigi Bragazzi, Mohammad Adawi
No abstract text is available yet for this article.
October 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29051833/anatomical-and-functional-correlation-in-susac-syndrome-multimodal-imaging-assessment
#2
Alexandre G B Azevedo, Luiz H Lima, Léo Müller, Flávio Rezende Filho, Cláudio Zett, André Maia, Luiz Roisman
BACKGROUND: Susac's syndrome (SuS) is an uncommon disease characterized by retinal microangiopathy that may be assessed more accurately with optical coherence tomography angiography (OCTA), a new imaging technique which provides a retinal microvasculature map. The purpose of this case report is to describe the multimodal imaging findings of SuS correlating OCTA with functional tests. CASE PRESENTATION: Retrospective review of one case with clinical and imaging evidence of SuS...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29016525/paracentral-acute-middle-maculopathy-in-susac-syndrome
#3
Ali S Haider, Deepa Viswanathan, David Williams, Peter Davies
PURPOSE: To present the first reported case of paracentral acute middle maculopathy in association with Susac syndrome. METHOD: Case report. RESULTS: A young female patient presented with unilateral sudden loss of vision of her right eye to count fingers. There were numerous cotton wool spots in a multifocal pattern concentrated around the right macula and optic disk. Clinical examination and spectral domain optical coherence tomography imaging were consistent with paracentral acute middle maculopathy, and fluorescein angiography showed features of retinal arteriole vasculitis...
October 9, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28987176/immune-mediated-disorders
#4
Romana Höftberger, Hans Lassmann
Paraneoplastic and autoimmune encephalitis comprise a group of immune-mediated disorders that are associated with different immune effector mechanisms. Classic paraneoplastic neurologic syndromes are triggered by an antitumor immune response. The disease is considered to result from a T-cell response; in addition, patients harbour high titers of autoantibodies against intracellular antigens that are considered as epiphenomenon but are useful diagnostic markers. Neuropathology consists of T-cell-dominated inflammation, marked neuronal loss, and microglial activation with upregulation of HLA-DR...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28959874/high-resolution-vessel-wall-imaging-of-three-patients-with-susac-s-syndrome
#5
Vance T Lehman, James P Klaas, Ashima Makol, Waleed Brinjikji, Deena M Nasr, Mahmud Mossa-Basha, George W Petty, John Huston
No abstract text is available yet for this article.
September 28, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28943023/susac-s-syndrome-a-case-of-autoimmune-encephalitis
#6
D Mora López, A Tristancho Garzon, M Guzmam Llorente, C Jiménez Conde, A Montero Urbina, P Oliva Fernandez
No abstract text is available yet for this article.
September 21, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/28933135/headache-in-a-young-woman-do-not-forget-susac-s-syndrome
#7
A Kefi, F Said, T Ben Salem, M Khedher, M Khanfir, I Ben Ghorbel, M Lamloum, M H Houman
Susac syndrome is a rare disease characterized by the clinical triad of encephalopathy, branch retinal artery occlusion, and sensorineural hearing loss. This underdiagnosed condition needs to be considered in the differential diagnosis of a broad variety of disorders. An early diagnosis is important as treatment can halt disease progression and prevent permanent disability. Herein, we report a case of Susac syndrome in a 31-year-old woman and we highlight how challenging an early diagnosis was and the importance of an aggressive therapeutic approach, including the combination of steroids and other cytotoxic drugs...
September 21, 2017: Reumatismo
https://www.readbyqxmd.com/read/28922012/neuropsychological-outcome-of-a-case-of-susac-syndrome-a-two-year-follow-up-study
#8
Andrew W Barritt, Mirdhu Wickremaratchi, Stuart J Anderson
Susac syndrome is a rare condition characterised by the clinical triad of encephalopathy, branch retinal artery occlusion, and sensorineural hearing loss. Of the few published cases, there is variability with regard to cognitive outcome. We describe the clinical course and neuropsychological performance of a 21-year-old male patient presenting with severe encephalopathy and later developing the full triad fulfilling the diagnosis of Susac syndrome.
September 18, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28899478/clinically-diagnosed-susac-syndrome-in-a-50-year-old
#9
Francesca M Brett, Seamus Looby, Conor Fearon, Peter Widdess-Walsh
No abstract text is available yet for this article.
September 7, 2017: Clinical Neuropathology
https://www.readbyqxmd.com/read/28893337/optimization-of-three-dimensional-3d-chemical-imaging-by-soft-x-ray-spectro-tomography-using-a-compressed-sensing-algorithm
#10
Juan Wu, Mirna Lerotic, Sean Collins, Rowan Leary, Zineb Saghi, Paul Midgley, Slava Berejnov, Darija Susac, Juergen Stumper, Gurvinder Singh, Adam P Hitchcock
Soft X-ray spectro-tomography provides three-dimensional (3D) chemical mapping based on natural X-ray absorption properties. Since radiation damage is intrinsic to X-ray absorption, it is important to find ways to maximize signal within a given dose. For tomography, using the smallest number of tilt series images that gives a faithful reconstruction is one such method. Compressed sensing (CS) methods have relatively recently been applied to tomographic reconstruction algorithms, providing faithful 3D reconstructions with a much smaller number of projection images than when conventional reconstruction methods are used...
October 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/28885997/susac-syndrome-the-first-case-report-in-peru
#11
Carolina Rivadeneira-Sotelo, María Meza Vega, Darwin Segura-Chávez, Sheila Castro-Suarez
Susac Syndrome is a rare entity, characterized by a triad of subacute encephalopathy, retinal artery occlusion and sensorineural hearing loss. It is more common in women and the age of onset fluctuates between 9-58 years of age. The pathogenesis is presented as microangiopathic changes at the cerebral, retinal and cochlear levels associated with an autoimmune mechanism. We present the case of a 31-year-old woman who started with a diffuse headache, puerile behavior, bradylalia and somnolence. As the disease progressed, she had auditory deficit and arterial obstruction of the right temporal retinal branch in retinal fluorescein angiography...
August 30, 2017: Medwave
https://www.readbyqxmd.com/read/28879939/a-report-of-third-case-of-susac-syndrome-from-india
#12
Kamble J Harsha, Jeevan S Nair
No abstract text is available yet for this article.
September 2017: Neurology India
https://www.readbyqxmd.com/read/28819045/fundus-fluorescein-angiography-in-susac-s-syndrome
#13
EDITORIAL
Gavin L Reynolds, Kevin Talbot, Srilakshmi M Sharma
No abstract text is available yet for this article.
August 17, 2017: Practical Neurology
https://www.readbyqxmd.com/read/28730399/optical-coherence-tomography-angiography-findings-in-susac-s-syndrome-a-case-report
#14
Rodolfo Mastropasqua, Lisa Toto, Alfonso Senatore, Alessandro D'Uffizi, Piergiorgio Neri, Cesare Mariotti, Marica Tina Maccarone, Luca Di Antonio
PURPOSE: To report clinical features of Susac's syndrome (SS) using optical coherence tomography angiography (OCTA). METHODS: Case report. RESULTS: A 25-year-old Caucasian female with a history of non-pulsatile migraine, tinnitus, and verbal apraxia complaining of peripheral scotoma in left eye due to branch retinal arteriole occlusion (BRAO) was diagnosed as having SS after audiometric test, brain magnetic resonance imaging, and multimodal retinal imaging...
July 20, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28725290/the-discovery-of-the-flammer-syndrome-a-historical-and-personal-perspective
#15
REVIEW
Josef Flammer, Katarzyna Konieczka
This review describes the clinical and basic research that led to the description of Flammer syndrome. It is narrated from a personal perspective. This research was initiated by the observation of an increased long-term fluctuation of visual fields in a subgroup of glaucoma patients. As these patients had strikingly cold hands, peripheral blood flow was tested with a capillary microscopy, and vasospastic syndrome (VS) was diagnosed. Further studies on these patients revealed frequently weakened autoregulation of ocular blood flow and increased flow resistivity in retroocular vessels...
June 2017: EPMA Journal
https://www.readbyqxmd.com/read/28705845/urodynamic-findings-in-susac-syndrome-first-reported-filling-cystometrogram
#16
Tatenda Calvin Nzenza, Nathan Hoag, Derek Barrry Hennessey, Johan Gani
Susac syndrome is a rare neurological disease, with only 300 cases reported in the literature. Lower urinary symptoms are not an uncommon feature of the disease, yet there is no information on specific dysfunction typical urodynamic findings associated with the disease. We present what we believe to be the first reported filling cystometrogram study of Susac syndrome for the evaluation of voiding dysfunction.
July 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28644112/susac-syndrome-misdiagnosed-as-multiple-sclerosis-with-exacerbation-by-interferon-beta-therapy
#17
Hussein Algahtani, Bader Shirah, Muhammad Amin, Eyad Altarazi, Hashem Almarzouki
Susac syndrome is a rare autoimmune disorder characterised by the clinical triad of encephalopathy, retinopathy (branch retinal artery occlusions) and hearing loss. The diagnosis of Susac syndrome may be difficult initially, and it is not uncommon for patients with Susac syndrome to be misdiagnosed with multiple sclerosis. In this case report, we describe a patient who was diagnosed as having multiple sclerosis for three years, with further deterioration after starting treatment with interferon beta-1a. The patient had the triad of encephalopathy, branch retinal artery occlusions and sensorineural hearing loss...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28641772/susac-syndrome-a-differential-diagnosis-of-white-matter-lesions
#18
Mariano Marrodan, Jorge Correale, Lucas Alessandro, Mariela Amaya, Maria Eugenia Fracaro, Alejandro Alfredo Köhler, Marcela Fiol
INTRODUCTION: Susac Syndrome is an autoimmune endotheliopathy affecting capillaries and precapillary arterioles of the brain, inner ear and retina. The classic symptom triad includes visual disturbances, hypoacusia, and encephalopathy, but is rarely fully manifest at onset. The syndrome typically follows an active fluctuating monophasic course. Typical imaging findings on brain magnetic resonance show central fiber microischemias/microinfarctions of the corpus callosum known as "snow balls", as well as lineal infarcts and upper callosal fiber involvement...
July 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28613358/oct-angiography-assessment-of-retinal-ischemia-in-susac-s-syndrome
#19
Karina Spiess, Jesús Ramón García Martínez
Descriptive study of two patients affected by Susac's syndrome (SuS) focusing on the chronic retinal tissue damage assessed by optical coherence tomography (OCT) and OCT angiography (OCTA). To the authors' knowledge, this is the first case series reporting OCTA in SuS. OCTA imaging revealed secondary hypoxia due to branch retinal artery occlusion of the deep capillary plexus, with additional involvement of the superficial capillary network in one case. OCTA is a noninvasive and quick diagnostic tool for detecting hypoxic retinal damage in SuS...
June 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28494240/cooperating-commensals-restore-colonization-resistance-to-vancomycin-resistant-enterococcus-faecium
#20
Silvia Caballero, Sohn Kim, Rebecca A Carter, Ingrid M Leiner, Bože Sušac, Liza Miller, Grace J Kim, Lilan Ling, Eric G Pamer
Antibiotic-mediated microbiota destruction and the consequent loss of colonization resistance can result in intestinal domination with vancomycin-resistant Enterococcus (VRE), leading to bloodstream infection in hospitalized patients. Clearance of VRE remains a challenging goal that, if achieved, would reduce systemic VRE infections and patient-to-patient transmission. Although obligate anaerobic commensal bacteria have been associated with colonization resistance to VRE, the specific bacterial species involved remain undefined...
May 10, 2017: Cell Host & Microbe
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