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https://www.readbyqxmd.com/read/28821058/exploration-of-permeability-and-antifouling-performance-on-modified-cellulose-acetate-ultrafiltration-membrane-with-cellulose-nanocrystals
#1
Jinling Lv, Guoquan Zhang, Hanmin Zhang, Fenglin Yang
Cellulose nanocrystals (CNCs) were introduced into cellulose diacetate (CDA) matrix via immerged phase-inversion process, aiming to improve the filtration and antifouling performance of CNCs/CDA blending membrane. The effects of CNCs on membrane morphologies, hydrophilicity, permeability and antifouling property were investigated. Results showed that the incorporation of CNCs into CDA membrane could effectively enhance the permeability and antifouling property of CNCs/CDA blending membrane by optimizing membrane microstructure and improving membrane hydrophilicity...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820572/on-the-functionality-selection-principle-for-high-voltage-lithium-ion-battery-electrolyte-additives
#2
Chi-Cheung Su, Meinan He, Cameron Peebles, Li Zeng, Adam Tornheim, Chen Liao, Lu Zhang, Jie Wang, Yan Wang, Zhengcheng Zhang
A new class of electrolyte additives based on cyclic fluorinated phosphate esters was rationally desgined and identified as being able to stabilize the surface of LiNi0.5Mn0.3Co0.2O2 (NMC532) cathode when cycled at potentials higher than 4.6 V vs. Li+/Li. Cyclic fluorinated phosphates were designed to incorporate functionalities of various existing additives to maximize their utilization. The synthesis and characterization of these new additives are described and their electrochemical performance in a NMC532/graphite cell cycled between 4...
August 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28820531/phytic-acid-assisted-electrochemically-synthesized-three-dimensional-o-p-functionalized-graphene-monoliths-with-high-capacitive-performance
#3
Han-Yu Li, Lang Liu, Zhi-Wei Zhang, Shu-Shen Wang, Yao Yu, Lin Liu, Yue Wu
Three-dimensional functionalized graphene monoliths (3DFGMs) have attracted intensive attention as energy storage materials due to their unique interconnected porous structure, good electrical conductivity, excellent mechanical strength, and pseudocapacitive characteristic. Herein, we report a facile, green and low-cost strategy through a simple, one-step electrochemical process in a phytic acid solution to fabricate a 3DFGM. The 3D porous structure and functionalization of graphene can be obtained simultaneously...
August 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28820483/a-microsomal-proteomics-view-of-h%C3%A2-o%C3%A2-and-aba-dependent-responses
#4
May Alqurashi, Ludivine Thomas, Chris Gehring, Claudius Marondedze
The plant hormone abscisic acid (ABA) modulates a number of plant developmental processes and responses to stress. In planta, ABA has been shown to induce reactive oxygen species (ROS) production through the action of plasma membrane-associated nicotinamide adenine dinucleotide phosphate (NADPH)-oxidases. Although quantitative proteomics studies have been performed to identify ABA- or hydrogen peroxide (H₂O₂)-dependent proteins, little is known about the ABA- and H₂O₂-dependent microsomal proteome changes...
August 18, 2017: Proteomes
https://www.readbyqxmd.com/read/28820316/cell-cycle-related-metabolism-and-mitochondrial-dynamics-in-a-replication-competent-pancreatic-beta-cell-line
#5
Chiara Montemurro, Suryakiran Vadrevu, Tatyana Gurlo, Alexandra E Butler, Kenny E Vongbunyong, Anton Petcherski, Orian S Shirihai, Leslie S Satin, Daniel Braas, Peter C Butler, Slavica Tudzarova
Cell replication is a fundamental attribute of growth and repair in multicellular organisms. Pancreatic beta-cells in adults rarely enter cell cycle, hindering the capacity for regeneration in diabetes. Efforts to drive beta-cells into cell cycle have so far largely focused on regulatory molecules such as cyclins and cyclin-dependent kinases (CDKs). Investigations in cancer biology have uncovered that adaptive changes in metabolism, the mitochondrial network, and cellular Ca(2+) are critical for permitting cells to progress through the cell cycle...
August 18, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28820012/effect-of-rotational-prosthetic-alignment-variation-on-tibiofemoral-contact-pressure-distribution-and-joint-kinematics-in-total-knee-replacement
#6
Xin Xie, Roy Rusly, John D DesJardins, Frank Voss, Kim Chillag, Martine LaBerge
In total knee replacement surgery, implant alignment is one of the most important criteria for successful long-term clinical outcome. During total knee replacement implantation, femoral and tibial alignment are determined through appropriate bone resections, which could vary based on patient anatomy, implant design and surgical technique and further influence loading conditions and clinical outcomes. The current research focused on three critical alignment parameters for total knee replacement insertion: femoral component internal/external (I/E) rotation, varus-valgus tibiofemoral angulation and posterior tibial slope...
August 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28819969/a-fast-and-universal-approach-to-encapsulating-transition-bimetal-oxide-nanoparticles-in-amorphous-carbon-nanotubes-under-atmospheric-environment-based-on-marangoni-effect
#7
Shuoyu Li, Yuyi Liu, Peisheng Guo, Chengxin Wang
Transitionmetal oxides nanoparticles capsuled in amorphous carbon nanotubes (ACNTs) are attractive anode materials of lithium ion batteries (LIBs). Here we firstly designed a fast and universal method with a hydromechanics conception which is called Marangoni flow to fabricating transition bimetal oxides (TBOs) in ACNTs composite with a better electrochemistry performance. Maragoni flows can produce a liquid column with several centimeters high in a tube with one side immersion in the liquid. The key point to induce a Marangoni flow is to make a gradient of the surface tension between the surface and the inside of the solution...
August 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28819699/cudc-907-a-dual-hdac-and-pi3k-inhibitor-reverses-platinum-drug-resistance
#8
Kenneth K W To, Li-Wu Fu
Platinum (Pt)-based anticancer drugs are the mainstay of treatment for solid cancers. However, resistance to Pt drugs develops rapidly, which can be caused by overexpression of multidrug resistance transporters and activation of DNA repair. CUDC-907 is a potent molecular targeted anticancer agent, rationally designed to simultaneously inhibit histone deacetylase (HDAC) and phosphatidylinositol 3-kinase (PI3K). We investigated the potentiation effect of CUDC-907 on Pt drugs in resistant cancer cells. ABCC2 stably-transfected HEK293 cells and two pairs of parental and Pt-resistant cancer cell lines were used to test for the circumvention of resistance by CUDC-907...
August 17, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/28819413/the-role-of-%C3%AE-catenin-in-the-initiation-and-metastasis-of-ta2-mice-spontaneous-breast-cancer
#9
Dan Zhang, Fei Fei, Shuyuan Li, Yongjie Zhao, Zhengduo Yang, Jie Qu, Xipeng Zhang, Yu Yin, Shiwu Zhang
Purpose: Tientsin Albino 2 (TA2) mice have a high incidence of spontaneous breast cancer. Tumor initiation is related to mouse mammary tumor virus (MMTV) infection. MMTV is hormonally regulated and may promote tumor formation via Wnt/β-catenin signaling pathway. This study attempts to clarify the relationship between β-catenin expression and the initiation and metastasis of spontaneous breast cancer in TA2 mice. Materials and Methods: Pathological samples illustrating the development of spontaneous breast cancer in TA2 mice were collected and the presence of virus particles was verified in the cancer tissue by electron microscope...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28819390/fluorofenidone-inhibits-the-proliferation-of-lung-adenocarcinoma-cells
#10
Zheng-Hao Deng, Jie Meng, Juan Tang, Gao-Yun Hu, Li-Jian Tao
Background: Lung carcinoma is the leading cause of malignant tumor related mortality in China in recent decades, and the development of new and effective therapies for patients with advanced lung carcinoma is needed. We recently found that fluorofenidone (FD), a newly developed pyridine compound, reduced the activation of Stat3 (Signal transducer and activator of transcription 3) in fibroblasts. Stat3 plays a crucial role in the development of lung cancer and may represent a new therapeutic target. In this study, we examined the effect of FD on human lung adenocarcinoma cells in vivo and in vitro...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28819249/carbon-nanotube-co3o4-nanocomposites-selectively-coated-by-polyaniline-for-high-performance-air-electrodes
#11
Jin Young Kim, Yong Joon Park
We herein report the preparation of carbon nanotube (CNT)/Co3O4 nanocomposites selectively coated with polyaniline (PANI) via an electropolymerization method, for use as an effective electrode material for Li-air (Li-O2) batteries. The Co3O4 catalyst attached to the CNTs facilitated the dissociation of reaction products and reduced the overpotential of the cells. As the carbon surface activates the side reactions, the PANI coating on the carbon surface of the electrode suppressed the side reaction at the electrode/Li2O2 and electrode/electrolyte interfaces, thus enhancing the cycle performance of the electrode...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819153/giant-onsite-electronic-entropy-enhances-the-performance-of-ceria-for-water-splitting
#12
S Shahab Naghavi, Antoine A Emery, Heine A Hansen, Fei Zhou, Vidvuds Ozolins, Chris Wolverton
Previous studies have shown that a large solid-state entropy of reduction increases the thermodynamic efficiency of metal oxides, such as ceria, for two-step thermochemical water splitting cycles. In this context, the configurational entropy arising from oxygen off-stoichiometry in the oxide, has been the focus of most previous work. Here we report a different source of entropy, the onsite electronic configurational entropy, arising from coupling between orbital and spin angular momenta in lanthanide f orbitals...
August 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28818999/short-term-arrival-strategies-for-endurance-exercise-performance-at-moderate-altitude
#13
Joshua L Foss, Keren Constantini, Timothy D Mickleborough, Robert F Chapman
For sea level-based endurance athletes who compete at moderate and high altitudes, many are not logistically able to arrive at altitude weeks prior to the event to fully acclimatize. For those who can only arrive at altitude the night before competition, we asked if there is a physiological and performance advantage in reducing altitude exposure time to two hours prior to competition. On three separate visits, ten cyclists completed overnight laboratory exposures of: 1) a 14-hour exposure to normobaric hypoxia (16...
August 17, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28818583/timing-of-fertile-period-for-successful-pregnancy-in-american-bully-dogs
#14
Sang-Eun Hahn, Young-Kwang Jo, Yun-Kyong Jin, Goo Jang
Determination of the timing of the estrus cycle is essential for fertile mating. There are physiological variations among breeds, between bitches, and between cycles of the same bitch. If serial monitoring and many tools are applied, the exact moment of ovulation could be pin-pointed. However, it leads to time and costly difficulties. Progesterone concentrations during estrus cycles follow a specific pattern, and it is largely used in timing of fertile period. Although it has similar pattern in general, it is likely that breed-specific differences exist...
July 26, 2017: Theriogenology
https://www.readbyqxmd.com/read/28818313/controlled-single-cell-cyclic-compression-and-transcription-analysis-a-pilot-study
#15
Paola Gavazzo, Loredana Petecchia, Paolo Facci, Massimo Vassalli, Federica Viti
An innovative platform for the study of the molecular mechanisms at the basis of mechanotransduction has been implemented, developing an experimental approach capable of providing controlled dynamic compression stimuli and retrieving the biomolecular response with single-cell sensitivity. The system provides the ability to perform compression-release cycles on single cells with controlled forces in the nN range and a user-defined repetition rate. Experimental procedures to perform qPCR from a small set of single cells were finely tuned...
August 12, 2017: Biophysical Chemistry
https://www.readbyqxmd.com/read/28818306/time-harmonic-ultrasound-elastography-of-the-descending-abdominal-aorta-initial-results
#16
Lars-Arne Schaafs, Heiko Tzschätzsch, Markus van der Giet, Alexander Reshetnik, Ingo G Steffen, Bernd Hamm, Jürgen Braun, Ingolf Sack, Thomas Elgeti
Stiffening of central large vessels is considered a key pathophysiologic factor within the cardiovascular system. Current diagnostic parameters such as pulse wave velocity (PWV) indirectly measure aortic stiffness, a hallmark of coronary diseases. The aim of the present study was to perform elastography of the proximal abdominal aorta based on externally induced time-harmonic shear waves. Experiments were performed in 30 healthy volunteers (25 young, 5 old, >50 y) and 5 patients with longstanding hypertension (PWV >10 m/s)...
August 14, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28818170/post-chemotherapy-neuroblastoma-like-differentiation-in-ewing-sarcoma-of-humerus-report-of-a-rare-case-with-review-of-literature
#17
Nasir Ud Din, Amna Qasim, Zubair Ahmad
A21-year patient initially presented with a fracture of the humerus following minor trauma. Abone scan and biopsy were done due to the suspicion of pathological fracture and the biopsy confirmed the diagnosis of Ewing Sarcoma (EWS). Two months after initial presentation, chemotherapy was started and 5 cycles were given over a span of 6 months. Surgical resection of the tumor was then performed. The post-chemotherapy resection specimen, on histological examination, showed the presence of areas of neuroblastoma-like differentiation in otherwise morphologically classic EWS...
July 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28818109/metastatic-colorectal-cancer-responsive-to-regorafenib-for-2-years-a-case-report
#18
Kenji Yoshino, Dai Manaka, Ryo Kudo, Shunpei Kanai, Eisei Mitsuoka, Satoshi Kanto, Shinya Hamasu, Sayuri Konishi, Ryuta Nishitai
BACKGROUND: Regorafenib is an oral multikinase inhibitor that has been demonstrated as clinically effective in patients with metastatic colorectal cancer in phase III studies. Although disease control was achieved in 40% of the pretreated patients with metastatic colorectal cancer in the pivotal studies, radiological response has rarely been reported. Severe adverse events associated with regorafenib are known to occur during the first and second courses of treatment. We present a case of a 62-year-old Japanese patient whose metastatic colorectal cancer has been responding to treatment with regorafenib for 2 years...
August 18, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28818107/patellofemoral-kinematics-in-dogs-with-cranial-cruciate-ligament-insufficiency-an-in-vivo-fluoroscopic-analysis-during-walking
#19
Stanley E Kim, Geoffrey J Zann, Selena Tinga, Erica J Moore, Antonio Pozzi, Scott A Banks
BACKGROUND: Complete rupture of the cranial cruciate ligament (CrCL) in dogs causes profound disturbance to stifle joint biomechanics. The objective of this study was to characterize the effects of cranial cruciate ligament (CrCL) insufficiency on patellofemoral (PF) kinematics in dogs during walking. Ten client-owned dogs (20-40 kg) with natural unilateral complete CrCL rupture were included. Dogs underwent computed tomographic scans to create digital bone-models of the patella and femur...
August 17, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28818079/which-physical-and-social-environmental-factors-are-most-important-for-adolescents-cycling-for-transport-an-experimental-study-using-manipulated-photographs
#20
Hannah Verhoeven, Ariane Ghekiere, Jelle Van Cauwenberg, Delfien Van Dyck, Ilse De Bourdeaudhuij, Peter Clarys, Benedicte Deforche
BACKGROUND: Ecological models emphasize that cycling for transport is determined by an interplay between individual, physical and social environmental factors. The current study investigated (a) which physical and social environmental factors determine adolescents' preferences towards cycling for transport and (b) which individual, physical and social environmental factors are associated with their intention to actually cycle for transport. METHODS: An online questionnaire consisting of questions on individual and social environmental variables, and 15 choice-based conjoint tasks with manipulated photographs was completed by 882 adolescents (55...
August 17, 2017: International Journal of Behavioral Nutrition and Physical Activity
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