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Donatella Del Sindaco, Maria Denitza Tinti, Giovanni Pulignano, Stefano Tolone, Giovanni Minardi, Massimo Uguccioni, Antonio Lax
In the setting of heart failure (HF) pharmacotherapy demonstrates a quantifiable improvement in exercise tolerance also in HF with preserved ejection fraction (HFpEF). For patients with HFpEF, often older, with higher prevalence of hypertension, diabetes mellitus, atrial fibrillation and other comorbidities, endpoints such as quality of life and functional capacity may be more clinically relevant. However several study show as the use of ACE-I and B-blocker were lesser than expected. Beta-blocker therapy is the keystone of pharmacotherapy of HF patients and exercise training is the essential core of rehabilitation programs, it is important to elucidate the relationship between these therapies...
2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
Pierfranco Terrosu
The net clinical benefit of aspirin in primary prevention is uncertain as the reduction in occlusive events needs to be balanced against the increase in gastro-intestinal and cerebral bleedings. The meta-analysis of ATT (Anti Thrombotic Trialists) Collaboration in 2009 showed that aspirin therapy in primary prevention was associated with 12% reduction in cardio-vascular events, due mainly to a reduction in non-fatal myocardial infarction (0.18% vs 0.23% per year, p<0.0001). However, the benefit in term of coronary events was almost balanced by the increase in major bleedings...
2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
I Flores-Gómez, M Bacardí-Gascón, A L Armendáriz-Anguiano, M E Pérez-Morales, A Jiménez-Cruz
INTRODUCTION: Social Support (SS) therapy can be an effective method of weight loss compared with conventional treatment (CT). OBJECTIVE: To evaluate RCT's using SS therapy on weight in subjects with overweight or obesity. METHODOLOGY: We reviewed all original articles published in MEDLINE/PubMed, SciELO, EBSCO, Google Scholar, from 2000 to August 2011, and one referred in a previous metanalisis, of RCT's of the effect of SS therapy on weight loss, with at least five months of treatment, compared with another therapy or a CT...
September 2012: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Túlio César Azevedo Alves, Giselli Santos Azevedo, Emannuela Santiago de Carvalho
BACKGROUND AND OBJECTIVES: Trigeminal neuralgia is a syndrome of chronic pain, characterized by paroxysms of excruciating pain which dramatically affect patients' quality of life. Systemic drug therapy is the first line treatment for this disease. This study aimed at evaluating efficacy, safety and tolerability of several pharmacologic treatments offered to trigeminal neuralgia patients, trying to supply evidences for clinical practice recommendations and to identify the needs for further research...
December 2004: Revista Brasileira de Anestesiologia
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