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https://www.readbyqxmd.com/read/28817733/changing-patterns-of-cataract-services-in-north-west-nigeria-2005-2016
#1
Nasiru Muhammad, Mohammed Dantani Adamu, Mpyet Caleb, Nuhu Mohammed Maishanu, Aliyu Mohammed Jabo, Muhammad Mansur Rabiu, Covadonga Bascaran, Sunday Isiyaku, Allen Foster
PURPOSE: This study was conducted to assess the impact of the eye care programme on cataract blindness and cataract surgical services in Sokoto, Nigeria over a 12 year period 2005-2016. METHODS: Data from the 2005 population based cross-sectional study of blindness in Sokoto state was re-analysed to obtain baseline estimates of the prevalence of cataract blindness and cataract surgical coverage for persons 50 years and over in Wurno health zone. A population based survey of a representative sample of persons 50 years and over in Wurno health zone was conducted in July 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28817155/genetic-variation-of-15-autosomal-strs-in-a-population-sample-of-bedouins-residing-in-the-area-of-the-fourth-nile-cataract-sudan
#2
Andrzej Ossowski, Jaroslaw Piatek, Miroslaw Parafiniuk, Aleksandra Pudlo, Witold Pepinski, Malgorzata Skawronska, Michal Szeremeta, Anna Niemcunowicz-Janica, Ireneusz Soltyszewski
The purpose of the paper was to report allelic frequencies of 15 autosomal STR markers (AmpFlSTR NGM PCR Amplification Kit) for Bedouin inhabitants in the area of the Fourth Nile Cataract in Sudan, and compute commonly used population and forensic biostatistical parameters. Buccal swabs were collected from 117 unrelated individuals. DNA was extracted using DNA QIAamp(®) DNA Mini Kit, and quantitated with Quantifiler Human Quantification Kit in a 7500 Real-Time PCR System. Amplification of 15 AmpFlSTR NGM PCR Kit loci was performed in PCR System 9700...
August 17, 2017: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/28816820/factors-that-influence-of-trabectome-surgery-for-glaucoma-patients
#3
Naoki Tojo, Shinya Abe, Atsushi Hayashi
BACKGROUND: The aim of this study was to investigate the factors that influence the outcome of trabectome surgery. METHODS: This was a retrospective nonrandomized study. Seventy-eight glaucoma patients (86 eyes) who underwent trabectome surgeries and were followed up for more than 12 months were included. We classified the subtypes of glaucoma as: primary open-angle glaucoma (23 eyes), pseudo-exfoliation glaucoma (58 eyes), and secondary glaucoma (5 eyes). Forty-seven eyes underwent cataract and trabectome surgeries simultaneously, and 39 underwent only trabectome surgery...
August 14, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28816213/association-of-presenile-cataract-with-galactose-1-phosphate-uridyl-transferase-gene-mutations
#4
Nitin Nema, Ravindra Kumar, Abha Verma, Sonam Verma, Kiran Chaturvedi
BACKGROUND: Presenile cataract is commonly idiopathic in origin. However, patients with presenile cataract could have an underlying genetic abnormality of galactose metabolism. We studied the association, if any, between idiopathic presenile cataract and galactose-1 -phosphate uridyl transferase (GALT) gene mutation. METHODS: We selected 50 patients with idiopathic presenile cataract, <45 years of age, and 50 age- and sex-matched controls for the study. Mutations in the GALT gene were determined by polymerase chain reaction restriction fragment length polymorphism...
March 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28814826/comparison-between-bilateral-implantation-of-a-trifocal-intraocular-lens-and-blended-implantation-of-two-bifocal-intraocular-lenses
#5
César Vilar, Wilson Takashi Hida, André Lins de Medeiros, Klayny Rafaella Pereira Magalhães, Patrick Frensel de Moraes Tzelikis, Mario Augusto Pereira Dias Chaves, Antônio Francisco Pimenta Motta, Pedro Carlos Carricondo, Milton Ruiz Alves, Walton Nosé
PURPOSE: To compare visual outcomes and performance between bilateral implantation of a diffractive trifocal intraocular lens (IOL) Acrysof(®)PanOptix(®) TFNT00 and blended implantation of two different near add power bifocal IOLs: Acrysof(®) Restor(®) SV25T0 in dominant eye and Acrysof(®) Restor(®) SN6AD1 in the nondominant eye. METHODS: This prospective, nonrandomized, consecutive and comparative study assessed 20 patients (40 eyes) who had bilateral cataract surgery performed using the IOLs described...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28814824/cataract-surgery-in-patients-with-pseudoex-foliation-syndrome-current-updates
#6
REVIEW
Luigi Fontana, Marco Coassin, Alfonso Iovieno, Antonio Moramarco, Luca Cimino
Pseudoexfoliation is a ubiquitous syndrome of multifactorial origin affecting elderly people by increasing the risk of cataract and secondary glaucoma development. Despite modern techniques and technologies for cataract surgery, pseudoexfoliation syndrome represents a challenge for surgeons because of the increased weakness of the zonular apparatus and limited pupil dilation. Due to the inherent difficulties during surgery, the risk of vitreous loss in these patients is several times higher than in cataract patients without pseudoexfoliation...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28812133/-watchful-waiting-as-a-therapeutic-principle-for-diseases-of-the-vitreoretinal-interface
#7
REVIEW
H Hoerauf, B Kirchhof
Elective surgery of the vitreoretinal interface is currently the most common reason for vitrectomy in Germany. The evaluation and correct interpretation of spectral domain optical coherence tomography (SD-OCT) images is of great importance but the indications for vitrectomy in macular surgery should be based more on patient symptoms and not only the OCT findings. Watchful waiting is highlighted as an alternative therapeutic option in individual patients. This article addresses a number of aspects and discrepancies between findings and patients' level of suffering based on binocular symptoms...
August 15, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28812127/-uveitis-in-juvenile-idiopathic-arthritis
#8
I Foeldvari, K Walscheid, A Heiligenhaus
BACKGROUND: Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA). It occurs, according to German registry data, in around 12% of JIA patients and can lead to a loss of vision, especially in cases of delayed diagnosis and/or inadequate therapy. OBJECTIVE: A review of current aspects of diagnosis and therapy was carried out. MATERIAL AND METHODS: This is a review article of the current literature. RESULTS: The risk of uveitis is significantly elevated in patients with an oligoarticular course of JIA, ANA positivity and young age at onset of JIA...
August 15, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28811796/visual-outcome-after-phacoemulsification-with-lens-implant-in-diabetic-and-non-diabetic-patients-a-comparative-study
#9
Abdul Rashid Shaikh, Abdul Haleem Mirani, Muhammad Saleh Memon, Muhammad Faisal Fahim
OBJECTIVE: To compare the visual outcomes of phacoemulsification surgery with intraocular lens (IOL) in persons with and without diabetes at end of follow-up. METHODS: This was a comparative, cross sectional, observational study with Non-probability, purposive sampling. After approval from "Research Ethical Committee of Isra Post-graduate Institute of Ophthalmology Karachi, 92 patients with cataract in one eye were selected. Patients were divided into two groups...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28810266/physiological-and-optical-alterations-precede-the-appearance-of-cataracts-in-cx46fs380-mice
#10
Peter J Minogue, Junyuan Gao, Rebecca K Zoltoski, Layne A Novak, Richard T Mathias, Eric C Beyer, Viviana M Berthoud
Purpose: Cx46fs380 mice model a human autosomal-dominant cataract caused by a mutant lens connexin46, Cx46. Lenses from Cx46fs380 mice develop cataracts that are first observed at ∼2 months in homozygotes and at ≥4 months in heterozygotes. The present studies were conducted to determine whether Cx46fs380 mouse lenses exhibited abnormalities before there are detectable cataracts. Methods: Lenses from wild-type and Cx46fs380 mice were studied at 1 to 3 months of age...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28809847/genome-wide-expression-datasets-of-anti-vegf-and-dexamethasone-treatment-of-angiogenesis-in-the-rat-cornea
#11
Anthony Mukwaya, Pierfrancesco Mirabelli, Anton Lennikov, Maria Xeroudaki, Mira Schaupper, Beatrice Peebo, Neil Lagali
Therapeutics against pathologic new blood vessel growth, particularly those targeting vascular endothelial growth factor (VEGF) are of enormous clinical interest. In the eye, where anti-VEGF agents are in widespread clinical use for treating retinal and corneal blindness, only partial or transient efficacy and resistance to anti-VEGF agents are among the major drawbacks. Conversely, corticosteroids have long been used in ophthalmology for their potency in suppressing inflammation and angiogenesis, but their broad biological activity can give rise to side effects such as glaucoma and cataract...
August 15, 2017: Scientific Data
https://www.readbyqxmd.com/read/28808644/the-comparative-study-of-refractive-index-variations-between-haigis-srk-t-and-hoffer-q-formulas-used-for-preoperative-biometry-calculation-in-patients-with-the-axial-length-25-mm
#12
Hasan Razmjoo, Hosein Atarzadeh, Neda Kargar, Mohammad Behfarnia, Kobra Nasrollahi, Ali Kamali
BACKGROUND: To compare refractive index variation between Hoffer-Q, Haigis and SRK/T formulas used for preoperative biometry calculation in patients with axial length >25 mm, undergoing cataract surgery. MATERIALS AND METHODS: This is a randomized clinical trial study was performed on 54 eyes of 54 patients with ages of 40-70 years old and axial length >25 mm classified into three groups that their IOL POWER were calculated by Haigis, SRK/T and Hoffer-Q formulas before undergoing cataract surgery...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28807717/myofibroblast-transdifferentiation-the-dark-force-in-ocular-wound-healing-and-fibrosis
#13
REVIEW
Daisy Y Shu, Frank J Lovicu
Wound healing is one of the most complex biological processes to occur in life. Repair of tissue following injury involves dynamic interactions between multiple cell types, growth factors, inflammatory mediators and components of the extracellular matrix (ECM). Aberrant and uncontrolled wound healing leads to a non-functional mass of fibrotic tissue. In the eye, fibrotic disease disrupts the normally transparent ocular tissues resulting in irreversible loss of vision. A common feature in fibrotic eye disease is the transdifferentiation of cells into myofibroblasts that can occur through a process known as epithelial-mesenchymal transition (EMT)...
August 12, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28806956/mirnas-regulate-oxidative-stress-related-genes-via-binding-to-the-3-utr-and-tata-box-regions-a-new-hypothesis-for-cataract-pathogenesis
#14
Changrui Wu, Zhao Liu, Le Ma, Cheng Pei, Li Qin, Ning Gao, Jun Li, Yue Yin
BACKGROUND: Age-related cataracts are related to oxidative stress. However, the genome-wide screening of cataract related oxidative stress related genes are not thoroughly investigated. Our study aims to identify cataract regulated miRNA target genes that are related to oxidative stress and to propose a new possible mechanism for cataract formation. METHODS: Microarrays were used to determine the mRNA expression profiles of both transparent and cataractous lenses...
August 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28805198/severe-reversible-hypocalcemic-cardiomyopathy-diagnosed-36-years-after-subtotal-thyroidectomy-a-case-report
#15
Waldemar Elikowski, Małgorzata Małek-Elikowska, Patrycja Lachowska-Kotowska
Chronic hypocalcemia, irrespectively of its etiology, can lead to severe impairment of the left ventricular (LV) contractility manifesting as dilated cardiomyopathy, usually defined as hypocalcemic cardiomyopathy (hypocaCM). This rarely diagnosed type of heart failure (HF), can be completely reversible, when treated properly with calcium and vitamin D supplementation or, in some subjects, with human recombinant parathormone. A CASE REPORT: The authors present a case of a 60-year-old male admitted with advanced pulmonary congestion, recurrent pulmonary edema and pleural effusion...
July 21, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28804665/management-of-traumatic-cataract-with-posterior-capsular-rupture-a-case-report-and-in-vitro-model-study
#16
Wenjuan Wan, Ke Hu, Yan Ji, Can Li
PURPOSE: To investigate the optimal strategy for surgical management of traumatic cataract with posterior capsular rupture. METHODS: We describe four cases of traumatic cataract with posterior capsular rupture and an in vitro model built to evaluate the optimal infusion pressure during surgery. RESULTS: All patients underwent cataract surgery. By using an anterior chamber maintainer to elevate infusion pressure, we safely performed cataract extraction without phacoemulsification...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/28804247/ophthalmology-in-north-america-early-stories-1491-1801
#17
REVIEW
Christopher T Leffler, Stephen G Schwartz, Ricardo D Wainsztein, Adam Pflugrath, Eric Peterson
New World plants, such as tobacco, tomato, and chili, were held to have beneficial effects on the eyes. Indigenous healers rubbed or scraped the eyes or eyelids to treat inflammation, corneal opacities, and even eye irritation from smoke. European settlers used harsh treatments, such as bleeding and blistering, when the eyes were inflamed or had loss of vision with a normal appearance (gutta serena). In New Spain, surgery for corneal opacity was performed in 1601 and cataract couching in 1611. North American physicians knew of contralateral loss of vision after trauma or surgery (sympathetic ophthalmia), which they called "sympathy...
2017: Ophthalmology and Eye Diseases
https://www.readbyqxmd.com/read/28803418/clinical-results-after-microincision-biaxial-cataract-surgery-and-implantation-of-an-incise-intraocular-lens
#18
Wojciech Lubiński, Marta Kirkiewicz, Karolina Podborączyńska-Jodko
PURPOSE: To evaluate clinical outcomes after uncomplicated microincision biaxial cataract surgery and implantation of Incise intraocular lens (IOL). METHODS: This study included 47 eyes of 29 patients (mean age 62.2 ± 8.6 years), who underwent 1.4-mm biaxial cataract surgery with implantation of the Incise IOL (Bausch and Lomb). At third month, surgically induced astigmatism (SIA) was calculated. Three, 6 and 12 months postoperatively, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), corrected near visual acuity (CNVA) LogMAR ETDRS, spherical equivalent refraction (SER), photopic distance corrected contrast sensitivity (CS) with and without glare (85 cd/m(2)) (CSV-1000) were assessed...
August 12, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28803239/therapeutic-effect-of-0-1-tacrolimus-eye-drops-in-the-tarsal-form-of-vernal-keratoconjunctivitis
#19
Qi Wan, Jing Tang, Yu Han, Dan Wang, Hongquan Ye
OBJECTIVE: The purpose of this study was to evaluate the efficacy and safety of 0.1% tacrolimus eye drops in the tarsal form of vernal keratoconjunctivitis (VKC) and to survey the changes of dendritic cells at the palpebral conjunctiva in patients with VKC by in vivo confocal microscopy. METHODS: A total of 17 patients (34 eyes) with the tarsal form of VKC were enrolled in this prospective, nonrandomized case series. They were treated with 0.1% tacrolimus eye drops twice daily after discontinuation of all other topical medications...
August 12, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28803024/a-comparison-of-splicing-assays-to-detect-an-intronic-variant-of-the-ocrl-gene-in-lowe-syndrome
#20
Keita Nakanishi, Kandai Nozu, Ryugo Hiramoto, Shogo Minamikawa, Tomohiko Yamamura, Junya Fujimura, Tomoko Horinouchi, Takeshi Ninchoji, Hiroshi Kaito, Naoya Morisada, Shingo Ishimori, Koichi Nakanishi, Ichiro Morioka, Hiroyuki Awano, Masafumi Matsuo, Kazumoto Iijima
Lowe syndrome is an X-linked inherited disorder diagnosed by congenital cataracts, intellectual impairment, and renal tubular dysfunction. It is caused by pathogenic variants of the oculocerebrorenal syndrome of Lowe gene (OCRL), of which more than 250 have been reported so far. Around 30 of these variants are intronic nucleotide changes; however, to show the pathogenicity of these variants is usually laborious. In this report, we conducted genetic testing of a patient clinically diagnosed with Lowe syndrome to detect the presence of OCRL variants...
August 9, 2017: European Journal of Medical Genetics
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