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Obesity surgery trial

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https://www.readbyqxmd.com/read/28444355/improvement-in-obstructive-sleep-apnea-with-weight-loss-is-dependent-on-body-position-during-sleep
#1
Simon A Joosten, Jun K Khoo, Bradley A Edwards, Shane A Landry, Matthew T Naughton, John B Dixon, Garun S Hamilton
Study Objectives: Weight loss fails to resolve obstructive sleep apnea (OSA) in most patients, however it is unknown as to whether weight loss differentially affects OSA in the supine compared to non-supine sleeping positions. We aimed to determine if weight loss in obese OSA patients results in a greater reduction in the non-supine Apnea Hypopnea Index (AHI) compared to the supine AHI, thus converting subjects into supine predominant OSA. Methods: Post hoc analysis of data from a randomized controlled trial assessing the effect of weight loss (bariatric surgery vs medical weight loss) on OSA in 60 obese subjects (body mass index: >35 and <55) with recently diagnosed (<6 months) OSA and AHI of ≥ 20 events/hour...
April 21, 2017: Sleep
https://www.readbyqxmd.com/read/28440517/-efficacy-and-future-of-endoscopic-bariatric-surgery-in-the-treatment-of-obesity-and-metabolic-diseases
#2
Shangjia Huang, Junchang Zhang, Zhiyong Dong, Cunchuan Wang
The emerging endoscopic technologies are proved to be effective treatments for obesity in selected patients and to offer the potential advantages of reduced invasiveness, reversibility and repeatability. From the view of operation principle, endoscopic technologies can be classified as restrictive procedure, malabsorption procedure and endoscopic revision of gastric bypass. Restrictive procedures include intragastric balloon, aspiration therapy, endoscopic sleeve gastroplasty (ESG) and transoral gastroplasty...
April 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28439568/bariatric-surgery-and-kidney-related-outcomes
#3
Alex R Chang, Morgan E Grams, Sankar D Navaneethan
The prevalence of severe obesity in both the general and the chronic kidney disease (CKD) populations continues to rise, with more than one-fifth of CKD patients in the United States having a body mass index of ≥35 kg/m(2). Severe obesity has significant renal consequences, including increased risk of end-stage renal disease (ESRD) and nephrolithiasis. Bariatric surgery represents an effective method for achieving sustained weight loss, and evidence from randomized controlled trials suggests that bariatric surgery is also effective in improving blood pressure, reducing hyperglycemia, and even inducing diabetes remission...
March 2017: KI Reports
https://www.readbyqxmd.com/read/28436715/controlled-invasive-mechanical-ventilation-strategies-in-obese-patients-undergoing-surgery
#4
Lígia de Albuquerque Maia, Pedro Leme Silva, Paolo Pelosi, Patricia Rieken Macedo Rocco
The obesity prevalence is increasing in surgical population. As the number of obese surgical patients increases, so does the demand for mechanical ventilation. Nevertheless, ventilatory strategies in this population are challenging, since obesity results in pathophysiological changes in respiratory function. Areas covered: We reviewed the impact of obesity on respiratory system and the effects of controlled invasive mechanical ventilation strategies in obese patients undergoing surgery. To date, there is no consensus regarding the optimal invasive mechanical ventilation strategy for obese surgical patients, and no evidence that possible intraoperative beneficial effects on oxygenation and mechanics translate into better postoperative pulmonary function or improved outcomes...
April 24, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28417575/effect-of-weight-reduction-on-hemoglobin-a1c-in-weight-loss-trials-of-type-2-diabetes-patients
#5
Anders Gummesson, Elisabeth Nyman, Mikael Knutsson, Martin Karpefors
AIMS: To quantify the effect of weight loss on HbA1c at group level based on data from published weight loss trials in overweight and obese type 2 diabetes patients. METHODS: A systematic literature search in MEDLINE, EMBASE and Cochrane CENTRAL (January 1990 through December 2012) was conducted to identify prospective trials of energy-reduced diets, obesity drugs or bariatric surgery conducted in adult, overweight and obese T2D patients. Based on clinical data from 3 to 24 months of follow-up, a linear model was developed to describe the effect of weight reduction on HbA1c...
April 18, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28399551/risks-factors-for-reoperation-in-patients-treated-surgically-for-degenerative-spondylolisthesis-a-subanalysis-of-the-8-year-data-from-the-sport-trial
#6
Michael C Gerling, Dante Leven, Peter G Passias, Virgnie Lafage, Kristina Bianco, Alexandra Lee, Tamara S Morgan, Jon D Lurie, Tor D Tosteson, Wenyan Zhao, Kevin F Spratt, Kristen Radcliff, Thomas J Errico
STUDY DESIGN: Retrospective analysis of prospective data from the degenerative spondylolisthesis (DS) arm of the Spine Patient Outcomes Research Trial. OBJECTIVE: To identify risk factors for reoperation in patients treated surgically for DS and compare outcomes between patients who underwent reoperation with non-reoperative patients. SUMMARY OF BACKGROUND DATA: Several studies have examined outcomes following surgery for DS, but few have identified risk factors for reoperation...
April 10, 2017: Spine
https://www.readbyqxmd.com/read/28396128/perioperative-analgesic-profile-of-dexmedetomidine-infusions-in-morbidly-obese-undergoing-bariatric-surgery-a-meta-analysis-and-trial-sequential-analysis
#7
Preet Mohinder Singh, Rajesh Panwar, Anuradha Borle, Jan P Mulier, Ashish Sinha, Basavana Goudra
BACKGROUND: Opioid-sparing analgesia for bariatric surgery in morbidly obese can potentially prevent catastrophic airway complications. Our meta-analysis attempts to consolidate the evidence on dexmedetomidine evaluating its analgesic and safety profile. METHODS: Trails comparing perioperative dexmedetomidine infusion to conventional analgesic regimens for bariatric surgery were searched. Comparisons were made for 24-hour and postanesthesia care unit (PACU) morphine consumed, PACU pain scores, postoperative nausea and vomiting pain scores, and heartrate...
March 10, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28389805/a-multicentric-prospective-study-evaluating-the-safety-and-efficacy-of-kii-%C3%A2-fios-%C3%A2-first-entry-trocar-in-laparoscopic-bariatric-surgery
#8
Marcelo Loureiro, Mohamad Ramadan, El Mehdi Skalli, Pierre Blanc, Jean Michel Fabre, David Nocca
INTRODUCTION: Laparoscopic surgery has evolved as an important field of surgery due to its clear benefits when compared to open laparotomy surgery. However, specific complications of laparoscopic surgery have been reported, of which the majority are complications associated with first entry to the abdominal cavity. The emergence of bariatric surgery, combined with the special considerations of the abdominal wall and cavity of obese patients, leads to seeking new modalities of access to the abdominal cavity in this specific population...
April 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28386755/rygb-produces-more-sustained-body-weight-loss-and-improvement-of-glycemic-control-compared-with-vsg-in-the-diet-induced-obese-mouse-model
#9
Zheng Hao, R Leigh Townsend, Michael B Mumphrey, Christopher D Morrison, Heike Münzberg, Hans-Rudolf Berthoud
BACKGROUND: Weight regain and type-2 diabetes relapse has been reported in a significant proportion of vertical sleeve gastrectomy (VSG) patients in some studies, but definitive conclusions regarding the long-term comparative effectiveness of VSG and Roux-en-Y gastric bypass (RYGB) surgery are lacking both in humans and rodent models. This study's objective was to compare the effects of murine models of VSG and RYGB surgery on body weight, body composition, food intake, energy expenditure, and glycemic control...
April 6, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28386638/effect-of-diet-induced-weight-loss-on-lipoprotein-a-levels-in-obese-individuals-with-and-without-type-2-diabetes
#10
Kirsten A Berk, Reyhana Yahya, Adrie J M Verhoeven, Jeanette Touw, Frank P Leijten, Elisabeth F van Rossum, Vincent L Wester, Mirjam A Lips, Hanno Pijl, Reinier Timman, Gertraud Erhart, Florian Kronenberg, Jeanine E Roeters van Lennep, Eric J G Sijbrands, Monique T Mulder
AIMS/HYPOTHESIS: Elevated levels of lipoprotein(a) [Lp(a)] are an independent risk factor for cardiovascular disease (CVD), particularly in individuals with type 2 diabetes. Although weight loss improves conventional risk factors for CVD in type 2 diabetes, the effects on Lp(a) are unknown and may influence the long-term outcome of CVD after diet-induced weight loss. The aim of this clinical study was to determine the effect of diet-induced weight loss on Lp(a) levels in obese individuals with type 2 diabetes...
April 6, 2017: Diabetologia
https://www.readbyqxmd.com/read/28383375/comparison-of-vaginal-hysterectomy-techniques-and-interventions-for-benign-indications-a-systematic-review
#11
Peter C Jeppson, Sunil Balgobin, David D Rahn, Kristen A Matteson, Alexis A Dieter, David R Ellington, Sarit O Aschkenazi, Cara Grimes, Mamta M Mamik, Ethan M Balk, Miles Murphy
OBJECTIVE: To create evidence-based clinical practice guidelines based on a systematic review of published literature regarding the risks and benefits of available preoperative, intraoperative, and postoperative technical steps and interventions at the time of vaginal hysterectomy for benign indications. DATA SOURCES: We systematically searched the literature to identify studies that compared technical steps or interventions during the preoperative, intraoperative, and postoperative periods surrounding vaginal hysterectomy...
May 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28381350/a-systematic-review-of-the-interrelation-between-diet-and-surgery-induced-weight-loss-and-vitamin-d-status
#12
REVIEW
Caroline Himbert, Jennifer Ose, Mahmoud Delphan, Cornelia M Ulrich
Obesity is a major global health problem and has been associated with vitamin D deficiency. Intentional weight loss may alter vitamin D status and, conversely, vitamin D supplementation has been hypothesized to aid in weight loss. A systematic literature search in PubMed/Medline identified 3173 articles of which 37 studies (randomized controlled trials (RCT) [n=17], non-RCTs [n=20]) are summarized as effect of: (I) diet-induced weight loss on vitamin D status (n=7), (II) vitamin D supplementation on diet-induced weight loss (n=11), (III) surgery-induced weight loss on vitamin D status (n=15), and (IV) vitamin D supplementation after surgery-induced weight loss on vitamin D status (n=5)...
February 2017: Nutrition Research
https://www.readbyqxmd.com/read/28376683/analyzing-the-effects-of-psychotherapy-on-weight-loss-after-laparoscopic-gastric-bypass-or-laparoscopic-adjustable-gastric-banding-in-patients-with-borderline-personality-disorder-a-prospective-study
#13
F Gallé, A Cirella, A M Salzano, V Di Onofrio, P Belfiore, G Liguori
BACKGROUND AND AIMS: Personality disorders are frequently associated with eating disorders in obese patients and may negatively affect weight loss and maintenance after bariatric surgery. This non-randomized study aimed to assess the effects of different psychotherapeutic interventions on weight loss in a sample of patients with borderline personality disorder who underwent laparoscopic gastric bypass or laparoscopic adjustable gastric banding. MATERIALS AND METHODS: A total of 153 bariatric patients meeting borderline personality disorder criteria were chosen voluntarily and consecutively to undergo an interpersonal individual treatment (n = 50), a dialectical behavioral group treatment (n = 50), or treatment as usual (n = 53) for a year after surgery...
April 1, 2017: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/28372953/noninvasive-positive-pressure-ventilation-in-the-immediate-post-bariatric-surgery-care-of-patients-with-obstructive-sleep-apnea-a-systematic-review
#14
REVIEW
Solomon Tong, Jonathan Gower, Austin Morgan, Kyle Gadbois, Gordon Wisbach
BACKGROUND: Obstructive sleep apnea is common in morbidly obese patients, and noninvasive positive pressure ventilation (NIPPV) is the standard treatment. Postoperatively, NIPPV is highly effective in preventing hypoxia and apneic episodes; however, the concern of gastric distention leading to increased risk of an anastomotic dehiscence limits universal acceptance. OBJECTIVE: To perform a systematic review of the literature to determine if the use of NIPPV during immediate post-bariatric surgery care is safe...
February 20, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28366412/effects-of-obesity-treatment-on-female-reproduction-results-do-not-match-expectations
#15
REVIEW
Richard S Legro
The adverse effects of obesity of female reproduction have been extensively documented. However, there are few prospective studies that have examined preconception weight loss interventions. There is a need to develop successful interventions with significant weight loss and compliance and most importantly document the effects of preconception interventions on important perinatal outcomes such as live birth and the health of the infant and mother. The existing data from randomized trials that come closest to meeting these criteria have failed to document improved live-birth rates after the intervention compared with control groups...
April 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28359099/pediatric-obesity-assessment-treatment-and-prevention-an-endocrine-society-clinical-practice-guideline
#16
Dennis M Styne, Silva A Arslanian, Ellen L Connor, Ismaa Sadaf Farooqi, M Hassan Murad, Janet H Silverstein, Jack A Yanovski
Cosponsoring Associations: The European Society of Endocrinology and the Pediatric Endocrine Society. This guideline was funded by the Endocrine Society. Objective: To formulate clinical practice guidelines for the assessment, treatment, and prevention of pediatric obesity. Participants: The participants include an Endocrine Society-appointed Task Force of 6 experts, a methodologist, and a medical writer. Evidence: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation approach to describe the strength of recommendations and the quality of evidence...
March 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28359092/the-association-of-weight-loss-and-cardiometabolic-outcomes-in-obese-children-systematic-review-and-meta-regression
#17
Tamim Rajjo, Jehad Almasri, Alaa Al Nofal, Wigdan Farah, Mouaz Alsawas, Ahmed T Ahmed, Khaled Mohammed, Amrit Kanwar, Noor Asi, Zhen Wang, Larry J Prokop, Mohammad Hassan Murad
Background: Excess body weight in children is associated with multiple immediate and long-term medical comorbidities. We aimed to identify the degree of reduction in excess body weight associated with cardiometabolic changes (lipid panel, liver function tests, systolic blood pressure (SBP), diastolic blood pressure, glycosylated hemoglobin, and fasting blood glucose) in overweight and obese children. Methods: We conducted a comprehensive search of MEDLINE, EMBASE, Cochrane Database of Systematic Reviews, and Scopus through February 12, 2015...
March 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28344345/gastric-bypass-surgery-with-exercise-alters-plasma-micrornas-that-predict-improvements-in-cardiometabolic-risk
#18
Y O Nunez Lopez, P M Coen, B H Goodpaster, A A Seyhan
BACKGROUND/OBJECTIVES: Roux-en-Y gastric bypass (RYGB) surgery improves insulin sensitivity (SI) and β-cell function in obese non-diabetic subjects. Exercise also improves SI and may be an effective adjunct therapy to RYGB surgery. However, the mechanisms by which exercise or weight loss improve peripheral SI after RYGB surgery are unclear. We hypothesized that microRNAs (miRNAs) mediate at least some of the regulatory processes driving such mechanisms. Consequently, this work aimed at profiling plasma miRNAs in participants of the Physical Activity Following Surgery Induced Weight Loss study (clinicaltrials...
April 25, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28314072/cordless-ultrasonic-dissector-versus-advanced-bipolar-vessel-sealing-device-for-laparoscopic-ovariectomy-in-dogs
#19
Anneleen L Spillebeen, Sara S D S Janssens, Rachel E Thomas, Jolle Kirpensteijn, Sebastiaan A van Nimwegen
OBJECTIVE: To compare Sonicision cordless ultrasonic dissector (SCUD) to LigaSure vessel sealing device (LVSD) for laparoscopic ovariectomy (Lap OVE) in dogs. STUDY DESIGN: Randomized, paired prospective clinical trial. ANIMALS: Client-owned dogs (n = 22) presented for elective Lap OVE. METHODS: Dogs were randomly assigned to one of two protocols: protocol 1 required the left ovary resected using SCUD and the right ovary using LVSD; protocol 2 required the left ovary resected using LVSD and the right ovary using SCUD...
March 17, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28282907/complications-from-surgeries-related-to-ovarian-cancer-screening
#20
Lauren A Baldwin, Edward J Pavlik, Emma Ueland, Hannah E Brown, Kelsey M Ladd, Bin Huang, Christopher P DeSimone, John R van Nagell, Frederick R Ueland, Rachel W Miller
The aim of this study was to evaluate complications of surgical intervention for participants in the Kentucky Ovarian Cancer Screening Program and compare results to those of the Prostate, Lung, Colorectal and Ovarian Cancer Screening trial. A retrospective database review included 657 patients who underwent surgery for a positive screen in the Kentucky Ovarian Cancer Screening Program from 1988-2014. Data were abstracted from operative reports, discharge summaries, and office notes for 406 patients. Another 142 patients with incomplete records were interviewed by phone...
March 8, 2017: Diagnostics
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