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Vladimir Musil, Josef Sach, David Kachlik, Matej Patzelt, Josef Stingl
PURPOSE: The aim of the study was to describe the origin of the Latin anatomical term vasa vasorum and its role in current medical research and to present examples of grammatical errors in its use. METHODS: Literary searches oriented on the term vasa vasorum were used to identify publications using it in the medical literature from the seventeenth century up to the present. RESULTS: The Latin term vasa vasorum was introduced by Ludwig in 1739...
July 18, 2018: Surgical and Radiologic Anatomy: SRA
Gino Seravalle, Fosca Quarti-Trevano, Raffaella Dell'Oro, Edoardo Gronda, Domenico Spaziani, Rita Facchetti, Cesare Cuspidi, Giuseppe Mancia, Guido Grassi
AIM: Although abnormalities in reflex sympathetic neural function represent a hallmark of heart failure, no information is available on the neuroadrenergic and baroreflex function in heart failure with preserved, midrange and reduced ejection fraction. The current study was designed to assess muscle sympathetic nerve traffic (MSNA) and baroreflex function in the clinical classes of heart failure defined by the new European Society of Cardiology/American College of Cardiology Foundation/American Heart Association guidelines...
July 16, 2018: Journal of Hypertension
Jiao Li, Yameng Cui, Anan Huang, Qi Li, Wenjun Jia, Keqiang Liu, Xin Qi
BACKGROUND Growth differentiation factor-15 (GDF-15) is a promising biomarker of cardiac remodeling. The purpose of this study was to explore the diagnostic value of plasma GDF-15 levels in different stages of heart failure (HF) and to assess the relationship with ventricular remodeling. MATERIAL AND METHODS We enrolled 219 HF patients from the Department of Cardiology in Tianjin Union Medical Center as the HF group and 32 healthy subjects as the control group. Circulating GDF-15, NT-proBNP, procollagen I C-terminal propeptide (PICP), and N-terminal procollagen III propeptide (PIIINP) levels were measured using ELISA...
July 18, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Eliseo Vano, Roberto Mariano Sanchez, Jose Miguel Fernández
The International Commission on Radiological Protection recommends that occupational protection and patient protection be managed in an integrated approach. This paper describes the experience and the initial results of a system able to register and to process simultaneously staff and patient doses in interventional cardiology and the practical use of this system in the optimisation of occupational exposure. The system used, simultaneously collects and manages patient and staff doses for all the radiation events...
July 18, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
Doris P Yimgang, John D Sorkin, Charles F Evans, Danielle S Abraham, Geoffrey L Rosenthal
INTRODUCTION: Angiotensin converting enzyme inhibitors are commonly prescribed medications after the Norwood procedure. There are little data that can be used to determine if angiotensin converting enzyme inhibitors improve interstage outcomes in children with single ventricle defects. The objective of this study was to investigate the relationship between angiotensin converting enzyme inhibitors and interstage failure among infants born with hypoplastic left heart syndrome. METHODS: We conducted a retrospective cohort study using data from the National Pediatric Cardiology Quality Improvement Collaborative database (collected between 2008 and 2015)...
July 17, 2018: Congenital Heart Disease
Anna Jonsson, Helena Norberg, Ellinor Bergdahl, Krister Lindmark
AIM: Previous studies and national assessments indicate an undertreatment of mineralocorticoid receptor antagonists (MRA) in heart failure with reduced ejection fraction (HFrEF). This study aims to investigate why MRA is not used to full extent. METHODS: A complete community based heart failure population was studied. Several variables were collected and medical records were scrutinized to identify reasons for not prescribing MRA. RESULTS: Of 2029 patients, 812 had EF ≤ 40%...
July 17, 2018: Cardiovascular Therapeutics
Rebecca L Tisdale, Zac Eggers, Lisa Shieh
Background: The majority of adverse events in healthcare involve communication breakdown. Physician-to-physician handoffs are particularly prone to communication errors, yet have been shown to be more complete when systematised according to a standardised bundle. Interventions that improve thoroughness of handoffs have not been widely studied. Aim: To measure the effect of an electronic medical record (EMR)-based handoff tool on handoff completeness. Intervention: This EMR-based handoff tool included a radio button prompting users to classify patients as stable, a 'watcher' or unstable...
2018: BMJ open quality
Alex Batten, Cassie Jaeger, David Griffen, Paula Harwood, Karen Baur
Acute myocardial infarction (AMI) follow-up care is a crucial part of the AMI recovery process. The American College of Cardiology's 'See You in 7 Challenge' advocates that all patients discharged with a diagnosis of AMI have a cardiac rehabilitation referral made and outpatient cardiac rehabilitation appointment scheduled to occur within 7 days of hospital discharge. A streamlined AMI cardiac rehabilitation referral and appointment scheduling process was not in place at this urban academic medical centre. To develop the streamlined processes, a Six Sigma project was initiated...
2018: BMJ Open Quality
Yi-Heng Li, Yu-Chen Wang, Yi-Chih Wang, Ju-Chi Liu, Cheng-Han Lee, Chun-Chi Chen, I-Chang Hsieh, Feng-You Kuo, Wei-Chun Huang, Shih-Hsien Sung, Chiung-Zuan Chiu, Jung-Cheng Hsu, Shu-Long Jen, Juey-Jen Hwang, Jiunn-Lee Lin
In Taiwan, the incidence of non-ST segment elevation acute coronary syndrome (NSTE-ACS) continues to increase in recent years. The purpose of this guideline is to help health care professionals in Taiwan to use adequate tests and treatments for management of NSTE-ACS. For rapid diagnosis, in addition to history and physical examination, 0/3 h rapid diagnosis protocol with high sensitivity cardiac troponin assay is recommended in this guideline. Dual antiplatelet and anticoagulation therapies are important parts in the initial treatment...
July 12, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
Birger Haarbrandt, Björn Schreiweis, Sabine Rey, Ulrich Sax, Simone Scheithauer, Otto Rienhoff, Petra Knaup-Gregori, Udo Bavendiek, Christoph Dieterich, Benedikt Brors, Inga Kraus, Caroline Marieken Thoms, Dirk Jäger, Volker Ellenrieder, Björn Bergh, Ramin Yahyapour, Roland Eils, HiGHmed Consortium, Michael Marschollek
INTRODUCTION: This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. HiGHmed brings together 24 partners from academia and industry, aiming at improvements in care provision, biomedical research and epidemiology. By establishing a shared information governance framework, data integration centers and an open platform architecture in cooperation with independent healthcare providers, the meaningful reuse of data will be facilitated...
July 2018: Methods of Information in Medicine
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2018: Cardiology
Andrea Caporali, Magnus Bäck, Mat J Daemen, Imo E Hoefer, Elizabeth A Jones, Esther Lutgens, Christian M Matter, Marie-Luce Bochaton-Piallat, Arndt F Siekmann, Judith C Sluimer, Sabine Steffens, José Tuñón, Cecile Vindis, Jolanda J Wentzel, Seppo Ylä-Herttuala, Paul C Evans
Modulation of vessel growth holds great promise for treatment of cardiovascular disease. Strategies to promote vascularization can potentially restore function in ischaemic tissues. On the other hand, plaque neovascularization has been shown to associate with vulnerable plaque phenotypes and adverse events. The current lack of clinical success in regulating vascularization illustrates the complexity of the vascularization process, which involves a delicate balance between pro- and anti-angiogenic regulators and effectors...
July 17, 2018: Cardiovascular Research
Marcello Chiocchi, Marco Forcina, Daniele Morosetti, Luca Pugliese, Armando Ugo Cavallo, Daniele Citraro, Vincenzo De Stasio, Matteo Presicce, Roberto Floris, Francesco Romeo
AIM: The aim of our study is to show the importance of multislice computed tomography (CT) assessment in the overall management and diagnostic framework of transcatheter aortic valve replacement (TAVI) procedure candidates. METHODS: Between June 2015 and April 2017, 200 patients with severe aortic stenosis, not eligible for surgery, were enrolled, as defined by EuroSCORE; they were submitted to TAVI at the interventional cardiology department of the Tor Vergata Polyclinic...
July 13, 2018: Journal of Cardiovascular Medicine
Paolo Guccione, Arianna Di Molfetta, Danilo Montefoschi, Roberto Formigari, Maria G Gagliardi
: Aneurysmatic fistulae are rare anomalies in infancy, which may lead to cardiac failure and ischemia. The right coronary artery (RCA) angiography of a 6-month-old infant showed a dilated RCA and an aneurysmatic conal branch draining through a fistula to the right ventricle. Angiography of the left coronary artery (LCA) demonstrates afferences from the anterior descending through a diagonal branch connecting the RCA distally to the origin of the fistula and from the marginal branch of the circumflex artery anastomosed with the RCA draining into the fistula...
July 13, 2018: Journal of Cardiovascular Medicine
Camille Chenevier-Gobeaux, Louis Deweerdt, Anne-Valérie Cantero, Bertrand Renaud, Bruno Desmaizières, Sandrine Charpentier, Aline Leroy, Emmanuelle Adelaïde, Delphine Collin-Chavagnac, Eric Bonnefoy-Cudraz, Laurence Estepa, Akli Chekroune, Sylvie Basco, Stéphane Andrieu, Stéphane Bourgeois, Marie-Agnès Costa, Christine Vallejo, Tiphaine Robert, Siham Ouahabi, Bruno Baudin, Benedicte Beneteau-Burnat, Anne-Marie Gorce-Dupuy, Patrick Ray, Claire Gast, Monique Dehoux, Guillaume Lefèvre
Objectives: We aimed to compare the use of nine different cardiac troponin (cTn) assays (2 cTnT and 7 cTnI) for the diagnosis of NSTEMI in a single multi-centre population. Design and methods: One hundred and fifty-eight patients were included (mean age 60 years, SD 17 years), including 23 patients (14%) with NSTEMI. Results: The analytical comparison highlighted a large heterogeneity of cTn assays, as reflected by percentages of patients with detectable cTn, correlation coefficients, Passing-Bablok comparisons and concordance coefficients...
July 2018: Practical Laboratory Medicine
Iva N Dimitrova, Georgi P Georgiev
Nowadays, the transradial approach is increasingly used for performing percutaneous coronary interventions and is preferred over the transfemoral approach. In the latest European Society of Cardiology guidelines (2017) for management of acute myocardial infarction in patients presenting with ST-segment elevation, the transradial approach is recommended over the transfemoral one if performed by an experienced radial operator (MATRIX study). Transradial procedure failures may be related to puncture failure, artery spasm, or to anatomical variations that require specific catheter handling or changing with a contralateral or transfemoral approach...
May 10, 2018: Curēus
Abdalla Ibrahim, Eoghan Meagher, Alexander Fraser, Thomas J Kiernan
A 34-year-old male presented with retrosternal chest pain, fatigue, shortness of breath, and a history of a previous episode of myocarditis four years prior. He had elevated troponin T, normal skeletal muscle enzymes, and negative inflammatory markers. Cardiac magnetic resonance imaging (MRI) confirmed active myocarditis with extensive myocardial fibrosis and normal left ventricular ejection fraction (LVEF). His myocarditis symptoms resolved with steroids and anti-inflammatory treatment, but on closer questioning, he reported a vague history of long-standing calf discomfort associated with episodes of stiffness, fatigue, and flu-like symptoms...
2018: Case Reports in Cardiology
Rachel A Lindor, Erika M McMahon, Joseph P Wood, Annie T Sadosty, Eric T Boie, Ronna L Campbell
Introduction: Anaphylaxis continues to cause significant morbidity and mortality. Healthcare providers struggle to promptly recognize and appropriately treat anaphylaxis patients. The goal of this study was to characterize anaphylaxis-related malpractice lawsuits. Methods: We collected jury verdicts, settlements, and court opinions regarding alleged medical malpractice involving anaphylaxis from May 2011 through May 2016 from an online legal database (Thomson Reuters Westlaw)...
July 2018: Western Journal of Emergency Medicine
Ebru Golcuk, Kivanc Yalin, Cansu Selcan Akdeniz, Erhan Teker, Başak Teker, Veysel Sabri Hancer, Ibrahim Altun, Murat Sezer, Reyhan Diz Kucukkaya, Aytac Oncul
Introduction: Glycoprotein Ibα (GPIbα) receptor is the chief molecule responsible for initial platelet adhesion to the subendothelium. A thymidine to cytosine single nucleotide substitution at position -5 from the ATG start codon characterizes the Kozak sequence polymorphism. The Kozak sequence polymorphism may increase the surface expression of GPIbα and contribute to thrombogenesis. We evaluated the allele frequencies of GPIbα Kozak sequence polymorphism in the Turkish population and examined the relationship between GPIbα Kozak sequence polymorphism and early-onset acute coronary syndrome (ACS)...
June 2018: Archives of Medical Science: AMS
Lindsey E Hunter, Anna N Seale
This review article will guide the reader through the background of prenatal screening for congenital heart disease. The reader will be given insight into the normal screening views, common abnormalities, risk stratification of lesions and also recent advances in prenatal cardiology.
July 16, 2018: Echo Research and Practice
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