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https://www.readbyqxmd.com/read/27914144/outdoor-air-pollution-and-pterygium-in-korea
#1
Ki Woong Lee, Yoon Hyeong Choi, Sung Ha Hwang, Hae Jung Paik, Mee Kum Kim, Won Ryang Wee, Dong Hyun Kim
We investigated relationships between outdoor air pollution and pterygium in Korean adults. This study includes 23,276 adults in population-based cross-sectional data using the Korea National Health and Nutrition Examination Survey 2008-2011. Pterygium was assessed using slit lamp biomicroscopy. Air pollution data (humidity, particulate matter with aerodynamic diameter less than 10 μm [PM₁₀], ozone [O₃], nitrogen dioxide [NO₂], and sulfur dioxide levels [SO₂]) for 2 years preceding the ocular examinations were acquired...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27913575/lowest-glucose-variability-and-hypoglycemia-are-observed-with-the-combination-of-a-glp-1-receptor-agonist-and-basal-insulin-variation-study
#2
Harpreet S Bajaj, Karri Venn, Chenglin Ye, Avril Patrick, Shivani Kalra, Hasnain Khandwala, Nadeem Aslam, David Twum-Barima, Ronnie Aronson
OBJECTIVE: There is a dearth of published literature comparing glucose variability (GV) between different insulin regimens in type 2 diabetes. This cohort study compares GV using continuous glucose monitoring (CGM) in patients with well-controlled type 2 diabetes using four common insulin regimens: basal insulin + oral drugs (BO), basal insulin + glucagon-like peptide 1 receptor agonist (GLP-1 RA) (BGLP), premixed insulin (PM), and basal-bolus insulin (BB). RESEARCH DESIGN AND METHODS: Consecutive patients from three endocrinology clinics who met study criteria-type 2 diabetes, age 18 to 80 years, BMI ≤ 45 kg/m(2), stable insulin regimen for a minimum of 6 months, and stable A1C value ≤7...
December 2, 2016: Diabetes Care
https://www.readbyqxmd.com/read/27913214/alk-rearranged-non-small-cell-lung-cancer-is-associated-with-a-high-rate-of-venous-thromboembolism
#3
Alona Zer, Mor Moskovitz, David M Hwang, Anat Hershko-Klement, Ludmila Fridel, Grzegorz J Korpanty, Elizabeth Dudnik, Nir Peled, Tzippy Shochat, Natasha B Leighl, Geoffrey Liu, Ronald Feld, Ronald Burkes, Mira Wollner, Ming-Sound Tsao, Frances A Shepherd
BACKGROUND: Patients with lung cancer are at increased risk for venous thromboembolism (VTE), particularly those receiving chemotherapy. It is estimated that 8% to 15% of patients with advanced non-small-cell lung cancer (NSCLC) experience a VTE in the course of their disease. The incidence in patients with specific molecular subtypes of NSCLC is unknown. We undertook this review to determine the incidence of VTE in patients with ALK (anaplastic lymphoma kinase)-rearranged NSCLC. PATIENTS AND METHODS: We identified all patients with ALK-rearranged NSCLC diagnosed and/or treated at the Princess Margaret Cancer Centre (PM CC) in Canada between July 2012 and January 2015...
October 26, 2016: Clinical Lung Cancer
https://www.readbyqxmd.com/read/27912999/palliative-care-and-physiatry-in-the-oncology-care-spectrum-an-opportunity-for-distinct-and-collaborative-approaches
#4
REVIEW
Vishwa S Raj, Julie K Silver, Terrence M Pugh, Jack B Fu
As cancer evolves from a terminal illness to a chronic medical condition, so too does the view of clinical services. Palliative care and physical medicine and rehabilitation (PM&R) will increase in acceptance because they provide a valuable resource. The overarching theme is improving cancer-related symptoms or treatment-related side effects, improving patient health-related quality of life, lessening caregiver burden, and valuing patient-centered care and shared decision making. Managing symptom burden may improve therapy participation/performance...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27911777/siderophore-based-microbial-adaptations-to-iron-scarcity-across-the-eastern-pacific-ocean
#5
Rene M Boiteau, Daniel R Mende, Nicholas J Hawco, Matthew R McIlvin, Jessica N Fitzsimmons, Mak A Saito, Peter N Sedwick, Edward F DeLong, Daniel J Repeta
Nearly all iron dissolved in the ocean is complexed by strong organic ligands of unknown composition. The effect of ligand composition on microbial iron acquisition is poorly understood, but amendment experiments using model ligands show they can facilitate or impede iron uptake depending on their identity. Here we show that siderophores, organic compounds synthesized by microbes to facilitate iron uptake, are a dynamic component of the marine ligand pool in the eastern tropical Pacific Ocean. Siderophore concentrations in iron-deficient waters averaged 9 pM, up to fivefold higher than in iron-rich coastal and nutrient-depleted oligotrophic waters, and were dominated by amphibactins, amphiphilic siderophores with cell membrane affinity...
December 1, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27911466/transparent-nanofibrous-mesh-self-assembled-from-molecular-legos-for-high-efficiency-air-filtration-with-new-functionalities
#6
Varun Kumar Singh, Sai Kishore Ravi, Wanxin Sun, Swee Ching Tan
Alarming levels of particulate matter pollution in air pose a serious health threat in several countries, therefore intriguing a strong need for an economic and a viable technology of air filtration. Current air purification technology is rather expensive with certain types even having the risk of emitting hazardous by-products. The authors have developed a multifunctional air filter inspired from the nasal hairs possessing an ability to specifically trap/exhale the foreign particles and allergens while still letting the air flow...
December 2, 2016: Small
https://www.readbyqxmd.com/read/27910545/commercial-counterboard-for-10-ns-software-correlator-for-photon-and-fluorescence-correlation-spectroscopy
#7
Matteo Molteni, Fabio Ferri
A 10 ns time resolution, multi-tau software correlator, capable of computing simultaneous autocorrelation (A-A, B-B) and cross (A-B) correlation functions at count rates up to ∼10 MHz, with no data loss, has been developed in LabVIEW and C++ by using the National Instrument timer/counterboard (NI PCIe-6612) and a fast Personal Computer (PC) (Intel Core i7-4790 Processor 3.60 GHz ). The correlator works by using two algorithms: for large lag times (τ ≳ 1 μs), a classical time-mode scheme, based on the measure of the number of pulses per time interval, is used; differently, for τ ≲ 1 μs a photon-mode (PM) scheme is adopted and the correlation function is retrieved from the sequence of the photon arrival times...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27909523/comparison-of-the-influence-of-right-atrial-septal-pacing-and-appendage-pacing-on-an-atrial-function-and-atrial-fibrillation-in-the-clinical-situation
#8
Mariko Tanaka Md, Kanae Su Md, Maki Oi Md, Yasuyo Motohashi Md, Kousuke Takahashi Md, Euihong Ko Md, Koji Hanazawa Md, Mamoru Toyofuku Md, Masahiko Kitada Md, Yousuke Yuzuki Md, Takashi Tamura Md
INTRODUCTION: Recently right atrial septal (RAS) pacing is often selected, but the benefit brought by RAS pacing has not been clear. The aim of this study was to evaluate the differences between RAS pacing and right appendage (RAA) pacing. METHODS: 223 consecutive new patients with a right atrial (RA) electrode during the period from January 2004 to December 2012 were studied retrospectively. They were observed regularly at our pacemaker (PM) clinic, and we measured paced P - sensed QRS interval (pPQi) and left atrial dimension (LAD) during the observation period, furthermore the onset of atrial fibrillation (AF) was assessed...
June 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27909502/combined-diagnostic-yield-of-tilt-table-test-and-implantable-loop-recorder-to-identify-patients-affected-by-severe-clinical-presentation-of-neurally-mediated-reflex-syncope-who-could-respond-to-cardiac-pacing
#9
Tomaino M, Unterhuber M, Sgobino P, Pescoller F, Manfrin M, Rauhe W
In this study we wanted to verify the diagnostic value of tilt table test (TTT) to predict the efficacy of cardiac pacing (PM) for preventing recurrences of neurally mediated reflex syncope (NMS) in patients with cardioinhibitory activity (CI) documented by implantable loop recorder (ILR). Among patients selected by ILR in the context of severe clinical presentation of NMS, we analysed those who underwent PM implantation. In this observational and retrospective study we wanted to verify the results of TTT in the groups of treated patients with and without recurrences...
April 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27908628/biomarkers-of-the-health-outcomes-associated-with-ambient-particulate-matter-exposure
#10
Lixin Yang, Xiang-Yu Hou, Yongjie Wei, Phong Thai, Fahe Chai
Epidemiologic evidence supports the positive association of cardiopulmonary morbidity and mortality, and lung cancer risk with exposure to airborne particulate matter (PM). Oxidative stress and inflammation have been proposed to be the major causal factors involved in mediating PM effects on both cardiovascular and pulmonary health outcomes. However, the mechanism whereby PM causes the health effects is not fully elucidated. To evaluate and investigate human exposure to PM, it is essential to have a specific, sensitive and robust characterization of individual exposure to PM...
November 29, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27908579/transient-elastography-in-patients-with-implanted-cardiac-rhythm-devices
#11
Mireen Friedrich-Rust, Fabian Schoelzel, Sven Linzbach, Joerg Bojunga, Stefan Zeuzem, Florian Seeger
BACKGROUND: At present the use of transient elastography (TE) in patients with pacemaker (PM) or implantable cardioverter defibrillator (ICD) devices is not recommended, since the safety due to the electromagnet embarked in the vibrator for producing the shearwave has not been evaluated. However, no adverse events of sonographic examinations in this patient group have been reported. AIMS: The aim of the present study was to evaluate the safety of TE in patients with PM or ICD...
November 17, 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/27908382/water-soluble-and-organic-extracts-of-airborne-particulate-matter-induce-micronuclei-in-human-lung-epithelial-a549-cells
#12
Isabel C Palacio, Silvia B M Barros, Deborah A Roubicek
The in vitro genotoxic effects of organic and water-soluble fractions of airborne particulate matter (PM10) with the cytokinesis blocked micronucleus (MN) test in human alveolar carcinoma cells A549 were investigated. Samples were collected in three different sites of São Paulo State, Brazil, and fifteen soluble metals and the sixteen EPÁs priority polycyclic aromatic hydrocarbons (PAH) were chemically determined. PAHs prevailing were fluoranthene and benzo(ghi)perylene. In the water-soluble extracts, highest concentration of metals was found for zinc, iron, and copper in all places of collection...
December 2016: Mutation Research
https://www.readbyqxmd.com/read/27908312/calcinosis-in-poly-dermatomyositis-clinical-and-laboratory-predictors-and-treatment-options
#13
Micaela Fredi, Francesca Bartoli, Ilaria Cavazzana, Angela Cerebelli, Nice Carabellese, Angela Tincani, Minoru Satoh, Franco Franceschini
OBJECTIVES: We aimed to identify the possible clinical and laboratory predictors of calcinosis in a cohort of patients with a diagnosis of polymyositis (PM) and dermatomyositis (DM). METHODS: We carried out a retrospective analysis of a cohort of myositis patients attending our clinic between January 2013 and May 2014. RESULTS: 74 patients (58 females, 16 males) with PM (30 cases), DM (30 cases), overlap syndrome (13 cases) and inclusion body myositis (1 case) were enrolled...
November 14, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27908173/pacemaker-and-icd-oversensing-induced-by-movements-near-the-mri-scanner-bore
#14
E Mattei, F Censi, G Calcagnini, R Falsaperla, E Genovese, A Napolitano, V Cannatà
PURPOSE: The effect of the movement near the MRI scanner bore for people with a pacemaker (PM) or an implantable cardioverter defibrillator (ICD) is experimentally evaluated and discussed. METHODS: The authors performed in vitro measurements on a saline-filled human-shaped phantom (male, 170 cm height), equipped first with an MR-conditional PM (bicameral configuration, DDD programming), then with an MR-conditional ICD (biventricular configuration, detection algorithms enable but shock delivery disable)...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27907206/intestinal-fluid-permeability-in-atlantic-salmon-salmo-salar-l-is-affected-by-dietary-protein-source
#15
Haibin Hu, Trond M Kortner, Karina Gajardo, Elvis Chikwati, John Tinsley, Åshild Krogdahl
In Atlantic salmon (Salmo salar L.), and also in other fish species, certain plant protein ingredients can increase fecal water content creating a diarrhea-like condition which may impair gut function and reduce fish growth. The present study aimed to strengthen understanding of the underlying mechanisms by observing effects of various alternative plant protein sources when replacing fish meal on expression of genes encoding proteins playing key roles in regulation of water transport across the mucosa of the distal intestine (DI)...
2016: PloS One
https://www.readbyqxmd.com/read/27907059/quantitative-and-selective-analysis-of-feline-growth-related-proteins-using-parallel-reaction-monitoring-high-resolution-mass-spectrometry
#16
Mårten Sundberg, Emma M Strage, Jonas Bergquist, Bodil S Holst, Margareta Ramström
Today immunoassays are widely used in veterinary medicine, but lack of species specific assays often necessitates the use of assays developed for human applications. Mass spectrometry (MS) is an attractive alternative due to high specificity and versatility, allowing for species-independent analysis. Targeted MS-based quantification methods are valuable complements to large scale shotgun analysis. A method referred to as parallel reaction monitoring (PRM), implemented on Orbitrap MS, has lately been presented as an excellent alternative to more traditional selected reaction monitoring/multiple reaction monitoring (SRM/MRM) methods...
2016: PloS One
https://www.readbyqxmd.com/read/27906312/widely-tunable-narrow-linewidth-external-cavity-gain-chip-laser-for-spectroscopy-between-1-0-1-1-%C3%A2%C2%B5m
#17
Dong K Shin, Bryce M Henson, Roman I Khakimov, Jacob A Ross, Colin J Dedman, Sean S Hodgman, Kenneth G H Baldwin, Andrew G Truscott
We have developed and characterised a stable, narrow linewidth external-cavity laser (ECL) tunable over 100 nm around 1080 nm, using a single-angled-facet gain chip. We propose the ECL as a low-cost, high-performance alternative to fibre and diode lasers in this wavelength range and demonstrate its capability through the spectroscopy of metastable helium. Within the coarse tuning range, the wavelength can be continuously tuned over 30 pm (7.8 GHz) without mode-hopping and modulated with bandwidths up to 3 kHz (piezo) and 37(3) kHz (current)...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906243/magnetically-controllable-silicon-microring-with-ferrofluid-cladding
#18
A El Amili, M C M M Souza, F Vallini, N C Frateschi, Y Fainman
We experimentally investigate the application of magnetic fluids (MFs) on integrated silicon photonics. Using a ferrofluid-clad silicon microring resonator, we demonstrate active control of resonances by applying an external magnetic field. Relatively high loaded quality factors on the order of 6000 are achieved, despite the optical losses introduced by the magnetic nanoparticles. We demonstrate resonance shifts of 185 pm in response to a 110 Oe strong magnetic field, corresponding to an overall refractive index change of -3...
December 1, 2016: Optics Letters
https://www.readbyqxmd.com/read/27906231/enhancement-of-the-pockels-effect-in-photonic-crystal-modulators-through-slow-light
#19
Peter Girouard, Zhifu Liu, Pice Chen, Young Kyu Jeong, Yongming Tu, Seng-Tiong Ho, Bruce W Wessels
We report a photonic crystal (PhC) optical modulator operating in the optical C band (1530-1565 nm) using barium titanate epitaxial thin films as the electro-optic (EO) medium. The PhC has hexagonal lattice symmetry and an extinction ratio of 9 dB. Due to the slow light enhancement of the EO coefficient near the PhC band edge, the driving electrode can be as short as a one millimeter. We report for the first time, to the best of our knowledge, at microwave frequencies from 10 to 45 GHz the effective EO coefficient and its enhancement through slow light effects...
December 1, 2016: Optics Letters
https://www.readbyqxmd.com/read/27906227/high-performance-humidity-sensor-based-on-a-polyvinyl-alcohol-coated-photonic-crystal-cavity
#20
Chenyang Zhao, Qingchen Yuan, Liang Fang, Xuetao Gan, Jianlin Zhao
We demonstrate a high-performance relative humidity (RH) sensor by coating a photonic crystal (PC) cavity with polyvinyl alcohol (PVA). Because a PC cavity's evanescent field strongly interacts with the coated moisture-sensitive PVA film, the resonant wavelength is modified remarkably under varying RH levels ranging from 30% to 90%. In a PC cavity coated with a 720 nm thick PVA, the sensor exhibits a linear spectrum sensitivity exceeding 129 pm/%RH over 40-90%RH, and the power interrogation presents a high sensitivity as 0...
December 1, 2016: Optics Letters
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