keyword
https://read.qxmd.com/read/38503055/update-on-the-sentinel-node-procedure-in-vulvar-cancer
#21
REVIEW
Willemijn L van der Kolk, Joost Bart, Ate J G van der Zee, Maaike H M Oonk
Early-stage vulvar cancer is managed by a local excision of the primary tumor and, if indicated, a sentinel node (SN) biopsy to assess the need for further groin treatment. With the SN procedure, many patients can be treated less radically and will experience less complications and morbidity compared with an inguinofemoral lymphadenectomy (IFL). Still, the SN procedure can be further optimized. Different tracers for detecting the SN are being investigated, aiming to optimize detection rates and decrease the burden of the procedure and short-term complications...
March 2024: Journal of the National Comprehensive Cancer Network: JNCCN
https://read.qxmd.com/read/38500348/rare-presentation-of-papillary-carcinoma-within-a-sentinel-lymph-node-in-a-patient-with-ductal-carcinoma-in-situ-of-the-breast-a-challenging-but-useful-case-report-discussion-regarding-displacement-or-true-metastasis
#22
JOURNAL ARTICLE
Fnu Sonam, Miglena K Komforti, James W Jakub, Lauren F Cornell, Kristin A Robinson
Papillary carcinoma of the breast is a rare histologic subtype of invasive breast cancer. In contrast, ductal carcinoma in situ (DCIS) is a noninvasive, nonobligate precursor to invasive mammary carcinoma, confined within the terminal duct lobular unit of the breast and surrounded by an intact myoepithelial cell layer at the stromal/epithelial interface. We present an unusual case in which a patient with only DCIS of the breast exhibited papillary carcinoma within a sentinel lymph node, leading to questions about the origin of the lymph node lesion-whether it represents a true metastasis or iatrogenic displacement during diagnostic procedures...
March 18, 2024: International Journal of Surgical Pathology
https://read.qxmd.com/read/38498075/monopolar-diathermy-versus-a-vessel-sealing-device-for-reducing-postoperative-drain-output-after-simple-mastectomy-randomized-clinical-trial
#23
RANDOMIZED CONTROLLED TRIAL
Stephen Keelan, Gavin P Dowling, Trudi Roche, Aisling Hegarty, Matthew G Davey, Amenah A Dhannoon, Sorcha O'Grady, Eithne Downey, Jarlath Bolger, Michael Boland, Jan Sorensen, Colm Power, Abeeda Butt, Chwanrow Baban, Arnold D K Hill
BACKGROUND: Electrosurgical devices are commonly used during mastectomy for simultaneous dissection and haemostasis, and can provide potential benefits regarding vessel and lymphatic ligation. The aim of this prospective RCT was to assess whether using a vessel-sealing device (LigaSure™) improves perioperative outcomes compared with monopolar diathermy when performing simple mastectomy. METHODS: Patients were recruited prospectively and randomized in a 1 : 1 manner to undergo simple mastectomy using either LigaSure™ or conventional monopolar diathermy at a single centre...
March 2, 2024: British Journal of Surgery
https://read.qxmd.com/read/38497534/rate-of-occult-metastasis-in-lip-squamous-cell-carcinoma-a-systematic-review-and-meta-analysis
#24
JOURNAL ARTICLE
Sagar Kansara, Evrim Oral, Indrani Sarkar, Vlad Sandulache, Rula Mualla, Rohan R Walvekar, William Ryan, Patrick Ha
OBJECTIVES: The rate of occult metastasis in lip cancer is poorly studied. Management of the regional nodal basin in lip cancer is thus controversial. This study sought to understand the true rate of micrometastasis in lip cancer. MATERIALS AND METHODS: Systematic review and meta-analysis was conducted of English language studies reporting lip cancer sentinel node biopsy results. Studies were obtained from the PubMed database between the years 2000 and 2023 using the search terms "sentinel node biopsy" and "squamous cell carcinoma...
March 18, 2024: Head & Neck
https://read.qxmd.com/read/38492992/long-term-outcomes-after-amputation-and-sentinel-node-biopsy-for-subungual-melanoma-a-single-institution-series
#25
JOURNAL ARTICLE
Cristian D Valenzuela, Graham Fowler, Kaiya Kozuma, Sonny Kusaka, John T Vetto
BACKGROUND: Subungual melanoma (SUM) is a rare tumor with historically poor outcomes. Thus, the benefit of proximal versus distal amputation in SUM remains unclear. METHODS: We performed a retrospective review of our prospectively-maintained institutional melanoma database, including SUM and non-subungual acral melanoma (AM) patients who underwent sentinel lymph node biopsy (SLNB) between 1999 and 2022. All SUMs had distal joint or proximal amputations. Primary endpoints were overall survival (OS) and recurrence free survival (RFS)...
February 24, 2024: American Journal of Surgery
https://read.qxmd.com/read/38490879/axillary-ultrasonography-for-early-stage-invasive-breast-cancer
#26
JOURNAL ARTICLE
Karen Jiang, Crystal Ma, Yuwei Yang, Elaine McKevitt, Jin-Si Pao, Rebecca Warburton, Carol Dingee, Jieun Newman- Bremang, Melina Deban, Amy Bazzarelli
BACKGROUND: Among women with early invasive breast cancer and 1-2 positive sentinel nodes, sentinel lymph node biopsy (SLNB) is non-inferior to axillary lymph node dissection (ALND).1-3 However, preoperative axillary ultrasonography (AxUS) may not be sensitive enough to discriminate burden of nodal metastasis in these patients, potentially leading to overtreatment.4-6 This study compares axillary operation rates in patients who did and did not receive preoperative AxUS, assessing its utility and risks for overtreatment...
March 8, 2024: American Journal of Surgery
https://read.qxmd.com/read/38490840/machine-learning-radiomics-based-prediction-of-non-sentinel-lymph-node-metastasis-in-chinese-breast-cancer-patients-with-1-2-positive-sentinel-lymph-nodes-a-multicenter-study
#27
JOURNAL ARTICLE
Guihan Lin, Weiyue Chen, Yingying Fan, Yi Zhou, Xia Li, Xin Hu, Xue Cheng, Mingzhen Chen, Chunli Kong, Minjiang Chen, Min Xu, Zhiyi Peng, Jiansong Ji
RATIONALE AND OBJECTIVES: This study aimed to construct a machine learning radiomics-based model using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) images to evaluate non-sentinel lymph node (NSLN) metastasis in Chinese breast cancer (BC) patients who underwent total mastectomy (TM) and had 1-2 positive sentinel lymph nodes (SLNs). MATERIALS AND METHODS: In total, 494 patients were retrospectively enrolled from two hospitals, and were divided into the training (n = 286), internal validation (n = 122), and external validation (n = 86) cohorts...
March 14, 2024: Academic Radiology
https://read.qxmd.com/read/38489985/complete-lymph-node-dissection-in-cutaneous-melanoma-patients-with-positive-sentinel-lymph-node-outcome-and-predictors-in-a-retrospective-cohort-study-over-16-years
#28
JOURNAL ARTICLE
Helena Baecher, Michael Gerken, Leonard Knoedler, Samuel Knoedler, Michael Alfertshofer, Monika Klinkhammer-Schalke, Mark Berneburg, Konstantin Drexler, Sebastian Haferkamp
BACKGROUND: In melanoma treatment, complete lymph node dissection (CLND) has been considered the therapeutic gold standard in patients with positive sentinel lymph node biopsy (SLNB). This long-held approach was revised in 2017, with recent evidence questioning the therapeutic benefit of CLND in malignant melanoma (MM) therapy. In this study, we aimed to fill this knowledge gap by retrospectively analyzing the impact of CLND on MM patients' survival. METHODS: We retrospectively analyzed the multi-center population-based Clinical Cancer Registry at the Tumor Center Regensburg (TUDOK) database (2004-2020) to identify patients who had been diagnosed with SLN-positive MM and underwent (non)invasive management thereof...
March 1, 2024: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://read.qxmd.com/read/38489558/indocyanine-green-fluorescence-applied-to-gynecologic-oncology-beyond-sentinel-lymph-node
#29
JOURNAL ARTICLE
M Loverro, N Bizzarri, F M Capomacchia, Rafał Watrowski, D Querleu, A Gioè, A Naldini, F Santullo, N Foschi, A Fagotti, G Scambia, F Fanfani
Indocyanine green (ICG), a well-known molecule employed in medicine for over five decades, has emerged as a versatile dye widely embraced across various surgical disciplines. In gynecologic oncology, its prevalent use revolves around the detection of sentinel lymph nodes. However, the true potential of ICG extends beyond this singular application, owing to its pragmatic utility, cost-effectiveness, and safety profile. Furthermore, ICG has been introduced in the theranostic landscape, marking a significant juncture in the evolution of its clinical utility...
March 15, 2024: International Journal of Surgery
https://read.qxmd.com/read/38485222/comparative-study-using-indocyanine-green-and-patent-blue-dye-for-sentinel-lymph-node-biopsy-in-patients-with-early-stage-cervical-cancer
#30
JOURNAL ARTICLE
Benedikt Wess, Christhardt Kohler, Andrea Plaikner, Samer El-Safadi, Thilo Schwandner, Ivo Meinhold-Heerlein, Giovanni Favero
ACKGROUND: Lymphatic involvement is the most important prognostic factor in early-stage cervical cancer. Sentinel lymph node biopsy is a viable alternative to systematic lymphadenectomy and may identify metastases more precisely. OBJECTIVE: To compare two tracers (indocyanine green and patent blue) to detect sentinel nodes. METHODS: A single-center, retrospective study of women treated due to early-stage cervical cancer (International Federation of Gynecology and Obstetrics 2009 IA1 with lymphovascular invasion, IA2, and IB1)...
March 14, 2024: International Journal of Gynecological Cancer
https://read.qxmd.com/read/38484493/evaluation-of-traditional-targeted-axillary-dissection-eligibility-criteria-for-node-positive-breast-cancer-after-neoadjuvant-chemotherapy-in-a-prospective-multicenter-registry
#31
JOURNAL ARTICLE
Catherine Loveland-Jones, John Gaughan, Abigail Caudle, Brittany Murphy, Laila Samiian, Stephanie Byrum, Kristen Brill, Pauline Germaine, Xinmin Zhang, Kay Yoon-Flannery, Teralyn Carter, Adrian Lopez, Ryan Gruner, Michele Fantazzio, Henry Kuerer
INTRODUCTION: Targeted axillary dissection (TAD) is performed after neoadjuvant systemic therapy (NST) to decrease the rate of non-therapeutic axillary dissection (ALND) for patients with node-positive breast cancer. In order to ensure the oncologic safety of TAD, eligibility criteria resulting in a low false negative rate (FNR) have been proposed. The purpose of this study was to evaluate the utility of the traditional criteria. METHODS: Data was collected from a prospective multicenter registry...
March 3, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38484297/esophageal-cancer-treatment-advances-and-need-for-screening
#32
JOURNAL ARTICLE
Daniel C Eisner
Esophageal cancer is a challenging malignancy that often is diagnosed in advanced stages, resulting in a poor prognosis. This article provides a comprehensive review of the two main types of esophageal cancer, esophageal squamous cell carcinoma and esophageal adenocarcinoma, and reviews epidemiology, risk factors, pathogenesis, diagnostic modalities, staging systems, and established and emerging treatments. Recent advancements in treatment for resectable and unresectable esophageal cancer also are explored...
March 14, 2024: JAAPA: Official Journal of the American Academy of Physician Assistants
https://read.qxmd.com/read/38482409/an-exploratory-study-of-whether-axillary-lymph-node-dissection-can-be-avoided-in-breast-cancer-patients-with-positive-lymph-nodes
#33
JOURNAL ARTICLE
Fei Ren, Chenxuan Yang, Jiaxiang Liu, Kexin Feng, Qingyao Shang, Xiyu Kang, Ruixuan Zhang, Li Li, Shuangtao Zhao, Xin Wang, Xiang Wang
BACKGROUND: Breast cancer patients with positive axillary lymph nodes usually require axillary lymph node dissection (ALND), with many postoperative complications, such as lymphedema. For these patients, whether sentinel lymph node biopsy (SLNB) can replace ALND has been a research hotspot in the field of breast cancer. This study developed two risk stratification models for predicting the clinical outcomes of breast cancer patients with positive axillary lymph nodes receiving SLNB alone or ALND to determine which patients could potentially avoid ALND...
February 29, 2024: Translational Cancer Research
https://read.qxmd.com/read/38481925/utilization-of-imaging-modalities-in-the-diagnosis-of-melanoma-a-scoping-review
#34
REVIEW
Lucas Shapiro, Mahi Basra, Hemangi Patel, Collin Payne, Brett Brazen, Alejandro Biglione
Melanomas arise de novo or in the context of a precursor lesion. Lesions typically grow radially and then undergo a vertical growth phase proceeding to local invasion and metastasis. This review describes the utility of different imaging modalities in diagnosis and melanocytic lesion monitoring. A literature search was performed in November 2023 utilizing EMBASE, Medline, and PubMed. The PRISMA diagram demonstrates the review process. Reflectance confocal microscopy (RCM) utilizes near-infrared light to help diagnose dermatologic lesions...
February 2024: Curēus
https://read.qxmd.com/read/38481240/lymphatic-drainage-of-sinonasal-malignancies-and-the-role-of-sentinel-node-biopsies
#35
JOURNAL ARTICLE
Fatemeh Kashani, B G Weiss, P Bartenstein, M Canis, F Haubner
BACKGROUND: Locoregional recurrence is a critical factor in the prognosis of sinonasal malignancies. Due to the rarity of these tumours, as well as the heterogeneity of histologies and anatomical subsites, there is little evidence regarding the rate and location of regional metastases in sinonasal malignancies. Elective regional lymph node dissection in the therapy of sinonasal malignancies has become controversial. On the one hand, elective regional lymph node dissection is considered to be an overtreatment in the cN0 cases...
March 13, 2024: Orphanet Journal of Rare Diseases
https://read.qxmd.com/read/38479804/robotic-sentinel-lymph-node-mapping-with-sensitive-firefly-for-endometrial-cancer-staging
#36
JOURNAL ARTICLE
Mary Katherine Anastasio, Alice Darling, Emma C Rossi
No abstract text is available yet for this article.
March 13, 2024: International Journal of Gynecological Cancer
https://read.qxmd.com/read/38477155/incidence-and-risk-factors-of-breast-cancer-related-lymphedema-in-korea-a-nationwide-retrospective-cohort-study
#37
JOURNAL ARTICLE
Ha Rim Ahn, Hyeong Eun Jeong, Choyun Jeong, Sang Yull Kang, Sung Hoo Jung, Hyun Jo Youn, Jong Seung Kim
BACKGROUND: Breast cancer-related lymphedema (BCRL) is a secondary lymphedema that occurs after breast cancer related treatments. BCRL develops from damage or dysfunction of the normally functioning lymphatic system due to surgery, radiation therapy and rarely due to cancer recurrence. This nationwide, retrospective study was aimed at investigating the incidence and risk factors of BCRL using the database of the Korean National Health Insurance Service (NHIS). METHODS: Patients with newly diagnosed breast cancer who underwent breast surgery from January 1, 2017 to December 31, 2020, were recruited...
March 11, 2024: International Journal of Surgery
https://read.qxmd.com/read/38473276/atypical-endometrial-hyperplasia-and-concurrent-cancer-a-comprehensive-overview-on-a-challenging-clinical-condition
#38
REVIEW
Luca Giannella, Camilla Grelloni, Marco Bernardi, Camilla Cicoli, Federica Lavezzo, Gianmarco Sartini, Leonardo Natalini, Mila Bordini, Martina Petrini, Jessica Petrucci, Tomas Terenzi, Giovanni Delli Carpini, Jacopo Di Giuseppe, Andrea Ciavattini
The present review regarding atypical endometrial hyperplasia (AEH) focused on the main debated factors regarding this challenging clinical condition: (i) predictive variables of occult endometrial cancer (EC); (ii) the rate of EC underestimation according to different endometrial sampling methods; and (iii) the appropriateness of lymph node status assessment. When cancer is detected, approximately 90% of cases include low-risk EC, although intermediate/high-risk cases have been found in 10-13% of women with cancer...
February 24, 2024: Cancers
https://read.qxmd.com/read/38473257/a-review-of-contemporary-guidelines-and-evidence-for-wide-local-excision-in-primary-cutaneous-melanoma-management
#39
REVIEW
Sophie E Orme, Marc D Moncrieff
Surgical wide local excision (WLE) remains the current standard of care for primary cutaneous melanoma. WLE is an elective procedure that aims to achieve locoregional disease control with minimal functional and cosmetic impairment. Despite several prospective randomised trials, the optimal extent of excision margin remains controversial, and this is reflected in the persistent lack of consensus in guidelines globally. Furthermore, there is now the added difficulty of interpreting existing trial data in the context of the evolving role of surgery in the management of melanoma, with our increased understanding of clinicopathologic and genomic prognostic markers leading to the often routine use of sentinel node biopsy (SNB) as a staging procedure, in addition to the development of adjuvant systemic therapies for high-risk disease...
February 23, 2024: Cancers
https://read.qxmd.com/read/38473023/visualization-methods-for-uterine-sentinel-lymph-nodes-in-early-stage-endometrial-carcinoma-a-comparative-analysis
#40
JOURNAL ARTICLE
Linas Andreika, Karolina Vankevičienė, Diana Ramašauskaitė, Vilius Rudaitis
BACKGROUND: Sentinel lymph node (SLN) biopsy in early-stage endometrial cancer is recommended over systematic lymphadenectomy due to reduced morbidity and comparable detection rates. The main objective of this study was to compare the overall and bilateral detection rates of SLN in early-stage endometrial cancer using three techniques. METHODS: a prospective cohort study was designed to detect the difference in SLN detection rate in three cohorts: Indocyanine green (ICG), methylene blue (MB), and tracer combination (ICG + MB)...
March 5, 2024: Diagnostics
keyword
keyword
1857
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.