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https://www.readbyqxmd.com/read/28076389/a-computational-study-on-the-relation-between-resting-heart-rate-and-atrial-fibrillation-hemodynamics-under-exercise
#1
Matteo Anselmino, Stefania Scarsoglio, Andrea Saglietto, Fiorenzo Gaita, Luca Ridolfi
AIMS: Clinical data indicating a heart rate (HR) target during rate control therapy for permanent atrial fibrillation (AF) and assessing its eventual relationship with reduced exercise tolerance are lacking. The present study aims at investigating the impact of resting HR on the hemodynamic response to exercise in permanent AF patients by means of a computational cardiovascular model. METHODS: The AF lumped-parameter model was run to simulate resting (1 Metabolic Equivalent of Task-MET) and various exercise conditions (4 METs: brisk walking; 6 METs: skiing; 8 METs: running), considering different resting HR (70 bpm for the slower resting HR-SHR-simulations, and 100 bpm for the higher resting HR-HHR-simulations)...
2017: PloS One
https://www.readbyqxmd.com/read/28074775/axillary-artery-transection-and-bilateral-pulmonary-embolism-after-anterior-shoulder-dislocation-case-report
#2
Betty Leclerc, François Loisel, Maxime Ferrier, Mazen Al Sayed, Simon Rinckenbach, Laurent Obert
INTRODUCTION: Anterior shoulder dislocation can be associated with vascular and neurological complications. However, axillary artery injury associated with shoulder dislocation is rare and extremely rare without bone fracture. An early diagnosis of these complications allows predicting long-term functional outcomes. METHODS: This article reports the case of a 66-year-old patient who presented an anterior shoulder dislocation after a ski fall without any neurological dysfunction or pulse deficit...
2017: SICOT-J
https://www.readbyqxmd.com/read/28074067/expression-of-the-ctla-4-ligand-cd86-on-plasmacytoid-dendritic-cells-pdc-predicts-risk-of-disease-recurrence-after-treatment-discontinuation-in-cml
#3
C Schütz, S Inselmann, S Sausslele, C T Dietz, M C Müller, E Eigendorff, C A Brendel, S K Metzelder, T H Brümmendorf, C Waller, J Dengler, M E Goebeler, R Herbst, G Freunek, S Hanzel, T Illmer, Y Wang, T Lange, F Finkernagel, R Hehlmann, M Huber, A Neubauer, A Hochhaus, J Guilhot, F X Mahon, M Pfirrmann, A Burchert
It is unknown, why only a minority of chronic myeloid leukemia (CML) patients sustains treatment free remission (TFR) after discontinuation of tyrosine kinase inhibitor (TKI) therapy in deep molecular remission (MR). Here we studied, whether expression of the T-cell inhibitory receptor (CTLA-4)-ligand CD86 (B7.2) on plasmacytoid dendritic cells (pDC) affects relapse risk after TKI cessation. CML patients in MR displayed significantly higher CD86(+)pDC frequencies than normal donors (P<0·0024), whereas TFR patients had consistently low CD86(+)pDC (n=12)...
January 11, 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/28059863/spatiotemporal-expression-of-ski-after-rat-spinal-cord-injury
#4
Kaisheng Zhou, Wei Nan, Dongliang Feng, Zhigang Yi, Yandong Zhu, Zaiyun Long, Sen Li, Haihong Zhang, Yamin Wu
Ski is an evolutionarily conserved protein and widely participates in the regulation of various pathological and physiological processes such as wound healing, liver regeneration, development of the embryonic nervous system, muscle differentiation, and progression of many kinds of tumors. However, the distribution and function of Ski in central nervous system lesion and disease remain unclear. In this study, we investigated the spatiotemporal expression of Ski in a spinal cord injury (SCI) model in adult rats...
January 2, 2017: Neuroreport
https://www.readbyqxmd.com/read/28054124/-severe-blunt-thoracic-trauma-caused-by-ski-collision
#5
S J Lochner, M Scherr, M Perl, C Grove
An approximately 25-year-old skier collided in a ski-run intersection. At high speed, he first hit another skier and then smashed into a snow cannon. He died from his injuries a short time later in hospital. A whole-body CT scan was conducted under resuscitation conditions, which was followed by an autopsy. The investigation revealed a severe blunt thoracic trauma as cause of death. The detailed analysis was the result of the combination of the two methods of investigation, CT scan and autopsy. The methods complemented each other effectively and allowed for a detailed presentation of the injury pattern...
January 4, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28052386/ecosystem-engineers-drive-creek-formation-in-salt-marshes
#6
Huy D Vu, Kazimierz Wie Ski, Steven C Pennings
Ecosystem engineers affect different organisms and processes in multiple ways at different spatial scales. Moreover, similar species may differ in their engineering effects for reasons that are not always clear. We examined the role of four species of burrowing crabs (Sesarma reticulatum, Eurytium limosum, Panopeus herbstii, Uca pugnax) in engineering tidal creek networks in salt marshes experiencing sea level rise. In the field, crab burrows were associated with heads of eroding creeks and the loss of plant (Spartina alterniflora) stems...
January 2017: Ecology
https://www.readbyqxmd.com/read/28052079/environmental-dna-detection-of-the-golden-tree-frog-phytotriades-auratus-in-bromeliads
#7
Jack D Torresdal, Aidan D Farrell, Caren S Goldberg
The analysis of environmental DNA (eDNA) is a powerful, non-destructive technique for detecting rare or hard to find freshwater organisms. In this study, we investigated the effectiveness of environmental DNA analysis as a method for detecting a rare amphibian, the golden tree frog (Phytotriades auratus). These frogs are believed to live exclusively within one species of tank bromeliad, Glomeropitcairnia erectiflora, found on the highest peaks of the island of Trinidad in the West Indies. Previous survey methods for this species involved bromeliad destruction, while here we collected and analyzed water samples from discrete pools within G...
2017: PloS One
https://www.readbyqxmd.com/read/28043316/treatment-of-shoulder-dislocation-with-greater-tuberosity-and-glenoid-fractures
#8
Shah Jehan, Najeeb Mohammad Akhi Baig, Jacob Der Tavitian
Large glenoid fractures are relatively uncommon with shoulder dislocation. Simultaneous glenoid and greater tuberosity fractures with anterior shoulder dislocation are very rare. We report on a 48-year right-handed male who sustained a fall during skiing. He had anterior shoulder dislocation combined with large glenoid fracture and greater tuberosity fracture. He was treated surgically with fixation of the glenoid and greater tuberosity fractures, using two different approaches. The deltopectoral approach with coracoid osteotomy and subscapularis split was used for glenoid fixation...
December 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28035587/prevalence-of-back-pain-in-sports-a-systematic-review-of-the-literature
#9
REVIEW
Katharina Trompeter, Daniela Fett, Petra Platen
BACKGROUND: Back pain is a frequent health problem in the general population. The epidemiology of back pain in the general population is well researched, but detailed data on the prevalence and risk factors of back pain in athletes are rare. OBJECTIVE: The primary objective was to review articles about back pain in athletes to provide an overview of its prevalence in different sports and compare its prevalence among various types of sports and the general population...
December 29, 2016: Sports Medicine
https://www.readbyqxmd.com/read/28030491/severe-injuries-associated-with-skiing-and-snowboarding-a-national-trauma-data-bank-study
#10
Amory de Roulet, Kenji Inaba, Aaron Strumwasser, Konstantinos Chouliaras, Demetrios Demetriades
BACKGROUND: Injuries following skiing and snowboarding accidents lead to an estimated 7,000 hospital admissions annually and present a significant burden to the health care system. The epidemiology, injury patterns, hospital resource utilization, and outcomes associated with these severe injuries need further characterization. METHODS: The National Trauma Data Bank was queried for the period 2007-2014 for admissions with injury severity score (ISS) >15 and ICD-9 codes 885...
December 23, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27980209/the-cryo-em-structure-of-a-ribosome-ski2-ski3-ski8-helicase-complex
#11
Christian Schmidt, Eva Kowalinski, Vivekanandan Shanmuganathan, Quentin Defenouillère, Katharina Braunger, André Heuer, Markus Pech, Abdelkader Namane, Otto Berninghausen, Micheline Fromont-Racine, Alain Jacquier, Elena Conti, Thomas Becker, Roland Beckmann
Ski2-Ski3-Ski8 (Ski) is a helicase complex functioning with the RNA-degrading exosome to mediate the 3'-5' messenger RNA (mRNA) decay in turnover and quality-control pathways. We report that the Ski complex directly associates with 80S ribosomes presenting a short mRNA 3' overhang. We determined the structure of an endogenous ribosome-Ski complex using cryo-electron microscopy (EM) with a local resolution of the Ski complex ranging from 4 angstroms (Å) in the core to about 10 Å for intrinsically flexible regions...
December 16, 2016: Science
https://www.readbyqxmd.com/read/27973212/the-longterm-cost-effectiveness-of-the-coaching-patients-on-achieving-cardiovascular-health-coach-program-in-type-2-diabetes-in-tasmania
#12
A J Palmer, M J Vale, C L Wells, C Ski, D R Thompson, L Si
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27969024/accuracy-of-anxiety-and-depression-screening-tools-in-heart-transplant-recipients
#13
Aaron Conway, Judith Sheridan, Joanne Maddicks-Law, Paul Fulbrook, Chantal F Ski, David R Thompson, Lynn V Doering
PURPOSE: The aim of this study was to assess the validity and reliability of psychological screening tools in outpatient heart transplant recipients. METHODS: Forty-eight heart transplant recipients completed the Patient Health Questionnaire 9-item scale (PHQ-9), Generalized Anxiety Disorder 7-item Scale (GAD-7), Kessler Psychological Distress 10-item Scale (K-10) and Medical Outcomes Short Form 36-item Health Survey. A structured psychological interview (Mini International Neuropsychiatric Interview Version 6) was conducted after completion of the questionnaires...
November 2016: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/27940540/analysis-of-l-a-2-the-helper-virus-of-k2-killer-toxin-encoding-m2-dsrna-and-of-l-bc-variants-from-wine-yeast-strain-populations-provides-new-insights-into-the-relationship-and-evolution-of-dsrna-viruses-of-yeast
#14
Nieves Rodríguez-Cousiño, Rosa Esteban
: Saccharomyces cerevisiae killer strains secrete a protein toxin active on non-killer strains of the same (or other) yeast species. Different killer toxins, K1, K2, K28 or Klus have been described. Each toxin is encoded by a medium size (1.5 to 2.3 kb) M dsRNA located in the cytoplasm. M dsRNAs require L-A helper virus for maintenance. L-A belongs to the Totiviridae family and its dsRNA genome of 4.6 kb codes for the major capsid protein Gag and a minor Gag-Pol protein which form the virions that separately encapsidate L-A or the M satellites...
December 9, 2016: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/27931775/rhythmic-wrist-movements-facilitate-the-soleus-h-reflex-and-non-voluntary-air-stepping-in-humans
#15
Irina A Solopova, Victor A Selionov, Egor O Blinov, Dmitri S Zhvansky, Yury P Ivanenko
Neural coupling between the upper and lower limbs during human walking is supported by modulation of cross-limb reflexes and the presence of rhythmic activity in the proximal arm muscles. Nevertheless, the involvement of distal arm muscles in cyclic movements and sensorimotor neuromodulation is also suggested given their step-synchronized activation in many locomotor-related tasks (e.g., swimming, skiing, climbing, cycling, crawling, etc.). Here we investigated the effect of rhythmic wrist movements, separately and in conjunction with arm swinging, on the characteristics of non-voluntary cyclic leg movements evoked by muscle vibration in a gravity neutral position and on the soleus H-reflex of the stationary legs...
December 5, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27922162/nonmelanoma-skin-cancer-in-mountain-guides-high-prevalence-and-lack-of-awareness-warrant-development-of-evidence-based-prevention-tools
#16
Alexander Zink, Elisabeth Koch, Florian Seifert, Markus Rotter, Christoph D Spinner, Tilo Biedermann
AIMS OF THE STUDY: Nonmelanoma skin cancer (NMSC) is the most common cancer in Switzerland and Europe. The main causative factor is exposure to ultraviolet radiation, which puts outdoor workers in general at a higher risk of developing NMSC than indoor workers. However, few studies have clinically examined the risk of developing NMSC to outdoor workers, especially mountain guides. We aimed to investigate the prevalence of NMSC and corresponding precancerous lesions, and the associated risk behaviour of mountain and ski guides in order to develop future prevention programmes...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27920219/the-proprotein-convertases-in-hypercholesterolemia-and-cardiovascular-diseases-emphasis-on-proprotein-convertase-subtilisin-kexin-9
#17
REVIEW
Nabil G Seidah, Marianne Abifadel, Stefan Prost, Catherine Boileau, Annik Prat
The secretory proprotein convertase (PC) family comprises nine members, as follows: PC1/3, PC2, furin, PC4, PC5/6, paired basic amino acid cleaving enzyme 4, PC7, subtilisin kexin isozyme 1/site 1 protease (SKI-1/S1P), and PC subtilisin/kexin type 9 (PCSK9). The first seven PCs cleave their substrates at single/paired basic residues and exhibit specific and often essential functions during development and/or in adulthood. The essential SKI-1/S1P cleaves membrane-bound transcription factors at nonbasic residues...
January 2017: Pharmacological Reviews
https://www.readbyqxmd.com/read/27918680/is-there-an-optimal-pole-length-for-double-poling-in-cross-country-skiing
#18
Franziska Onasch, Anthony Killick, Walter Herzog
The aim of this study was to determine the effects of pole length on energy cost and kinematics in cross country double poling. Seven sub-elite male athletes were tested using pole sets of different lengths (ranging between 77 and 98% of participants' body height). Tests were conducted on a treadmill, set to a 2% incline and an approximate racing speed. Poling forces, contact times, and oxygen uptake were measured throughout the testing. Pole length was positively correlated with ground contact time (r = .57, p < ...
December 5, 2016: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/27918675/biomechanics-in-paralympics-implications-for-performance
#19
Floor Morriën, Matthew J D Taylor, Florentina J Hettinga
PURPOSE: To provide an overview of biomechanical studies in Paralympic research and their relevance for performance in Paralympic sports. METHODS: Search terms ' Paralympic Biomechanics', 'Paralympic Sport Performance', 'Paralympic Athlete Performance', and Paralympic Athlete' were entered into the electronic database PubMed. RESULTS: Thirty-four studies were included. Biomechanical studies in Paralympics mainly contributed to performance enhancement by technical optimization (n=32) and/or injury prevention (n=6)...
December 5, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27915067/the-feasibility-and-effects-of-acupuncture-in-an-adolescent-nordic-ski-population
#20
Kristin L Garlanger, William H Fredericks, Alexander Do, Brent A Bauer, Edward R Laskowski
BACKGROUND: Studies investigating the use and effectiveness of acupuncture in adults after exercise have been well documented. Fewer studies involving acupuncture have been completed in the adolescent athlete population. To our knowledge, there are no published studies that investigate the use of acupuncture in adolescent athletes within their field of play. OBJECTIVE: To primarily assess the feasibility of performing acupuncture in adolescent Nordic skiers within their athletic environment, and secondarily to measure the effect of acupuncture on muscle soreness and sense of well-being...
November 30, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
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