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https://www.readbyqxmd.com/read/28816642/proteomic-analysis-of-the-human-olfactory-bulb
#1
Manjunath Dammalli, Gourav Dey, Anil K Madugundu, Manish Kumar, Benvil Rodrigues, Harsha Gowda, Bychapur Gowrishankar Siddaiah, Anita Mahadevan, Susarla Krishna Shankar, Thottethodi Subrahmanya Keshava Prasad
The importance of olfaction to human health and disease is often underappreciated. Olfactory dysfunction has been reported in association with a host of common complex diseases, including neurological diseases such as Alzheimer's disease and Parkinson's disease. For health, olfaction or the sense of smell is also important for most mammals, for optimal engagement with their environment. Indeed, animals have developed sophisticated olfactory systems to detect and interpret the rich information presented to them to assist in day-to-day activities such as locating food sources, differentiating food from poisons, identifying mates, promoting reproduction, avoiding predators, and averting death...
August 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28816393/sperm-donation-perinatal-outcomes-in-an-australian-population-cohort
#2
Damian Adams, Renae Fernandez, Vivienne Moore, Kristyn Willson, Alice Rumbold, Sheryl de Lacey, Wendy Scheil, Michael Davies
AIM: To compare perinatal outcomes for neonates conceived with donated sperm with those for neonates conceived spontaneously in an Australian population cohort. METHODS: Perinatal outcomes for all births in South Australia for the period January 1986-December 2002 were linked with assisted reproductive treatment records to determine those conceived from donated sperm. Birth outcome measures were analyzed using Student's t-test and logistic regression using generalized estimating equations to determine statistical significance...
August 17, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28815718/a-potential-high-risk-for-fatty-liver-disease-was-found-in-mice-generated-after-assisted-reproductive-techniques
#3
Gu Ll, Zhang Jj, Zheng Mm, Dong Gy, Xu Jy, Zhang Wy, Yibo Wu, Yang Yang, Zhu H
Abnormal gametogenesis and embryonic development may lead to poor health status of the offspring. The operations involved in the assisted reproductive technologies (ARTs) occur during the key stage of gametogenesis and early embryonic development. To assess the potential risk of abnormal lipid metabolism in the liver of adult ARTs offspring, two ARTs mice models derived from preimplantation genetic diagnosis (PGD group) and in vitro cultured embryos without biopsy (IVEM group) were constructed. And control mice were from in vivo naturally conceived (Normal group)...
August 16, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28815633/the-gas-that-fuels-the-engine-individuals-motivations-for-medicalisation
#4
Ann V Bell
It is well established that the drivers of medicalisation have shifted alongside changes in the institution of medicine. The process of medicalisation is no longer incited by macro processes of institutional prestige or control; rather, individual patients/consumers are pushing the process forward. The present study complicates this neat transition and examines the relationship between structure and agency using the case of assisted reproductive technology (ART), specifically the medicalisation of lesbian reproduction in the US...
August 16, 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28813274/parenting-in-new-family-forms
#5
REVIEW
Susan Golombok
This paper reviews research on parenting and child development in new family forms including families created by assisted reproductive technologies, same-sex parent families, and families headed by single mothers by choice. The research is examined in the context of the issues and concerns that have been raised regarding these families. The findings not only contest popular assumptions about the psychological consequences for children of being raised in new family forms but also challenge the supremacy of the traditional family...
June 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28811855/impact-of-the-great-east-japan-earthquake-and-fukushima-nuclear-power-plant-accident-on-assisted-reproductive-technology-in-fukushima-prefecture-the-fukushima-health-management-survey
#6
Masako Hayashi, Keiya Fujimori, Seiji Yasumura, Akihito Nakai
BACKGROUND: The aim of the study was to evaluate the incidences and obstetric outcomes of women who conceived using assisted reproductive technology (ART) procedures in Fukushima Prefecture before and after the Great East Japan Earthquake and Fukushima nuclear power plant accident. METHODS: Information was collected and analyzed from 12,070 women who conceived with or without ART in Fukushima Prefecture during the 9 months before and after the disaster. RESULTS: During the 9 months before and after the disaster, 138 (2...
September 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28811365/a-model-explaining-the-matrilateral-bias-in-alloparental-investment
#7
Gretchen Perry, Martin Daly
Maternal grandmothers invest more in childcare than paternal grandmothers. This bias is large where the expression of preferences is unconstrained by residential and lineage norms, and is detectable even where marriage removes women from their natal families. We maintain that the standard evolutionary explanation, paternity uncertainty, is incomplete, and present an expanded model incorporating effects of alloparents on the mother as well as on her children. Alloparenting lightens a mother's load and increases her residual nepotistic value: her expected fitness from later investments in personal reproduction and in her natal relatives...
August 15, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28807397/colorectal-endometriosis-associated-infertility-should-surgery-precede-art
#8
Sofiane Bendifallah, Horace Roman, Emmanuelle Mathieu d'Argent, Salma Touleimat, Jonathan Cohen, Emile Darai, Marcos Ballester
OBJECTIVE: To compare the impact of first-line assisted reproductive technology (ART; intracytoplasmic sperm injection [ICSI]-IVF) and first-line colorectal surgery followed by ART on fertility outcomes in women with colorectal endometriosis-associated infertility. DESIGN: Retrospective matched cohort study using propensity score (PS) matching (PSM) analysis. SETTING: University referral centers. PATIENT(S): A total of 110 women were analyzed from January 2005 to June 2014...
August 11, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28806374/long-acting-reversible-contraception-among-homeless-women-veterans-with-chronic-health-conditions-a-retrospective-cohort-study
#9
Lori M Gawron, Andrew Redd, Ying Suo, Warren Pettey, David K Turok, Adi V Gundlapalli
BACKGROUND: US women Veterans are at increased risk of homelessness and chronic health conditions associated with unintended pregnancy. Veterans Health Administration (VHA) provision of long-acting reversible contraception (LARC) can assist in healthy pregnancy planning. OBJECTIVES: To evaluate perinatal risk factors and LARC exposure in ever-homeless women Veterans. RESEARCH DESIGN: A retrospective cohort study of women Veterans using VHA administrative data from fiscal years 2002-2015...
September 2017: Medical Care
https://www.readbyqxmd.com/read/28799832/soldiers-preferences-regarding-sperm-preservation-posthumous-reproduction-and-attributes-of-a-potential-posthumous-mother
#10
Ya'arit Bokek-Cohen, Vardit Ravitsky
We present study results regarding soldiers' willingness to conduct posthumous reproduction. Two hundred twelve Israeli soldiers filled in a questionnaire designed to examine their willingness to cryopreserve sperm and evaluate in which familial circumstances they would consent to posthumous reproduction. They ranked the desirability of 46 attributes of a potential mother and a life partner. Findings indicate a relatively high predisposition in favor of posthumous-assisted reproduction; the wishes of soldiers' parents had much more influence on soldiers' willingness to pursue this technology than those of a partner...
January 1, 2017: Omega
https://www.readbyqxmd.com/read/28799634/effectiveness-of-highly-purified-urofollitropin-treatment-in-patients-with-idiopathic-azoospermia-before-testicular-sperm-extraction
#11
Andrea Cocci, Gianmartin Cito, Giorgio I Russo, Marco Falcone, Marco Capece, Massimiliano Timpano, Pier Andrea Della Camera, Simone Morselli, Giovanni Tasso, Girolamo Morelli, Giuseppe Morgia, Andrea Minervini, Sergio Serni, Marco Carini, Alessandro Natali, Mauro Gacci
INTRODUCTION: Recent evidences demonstrated that male factor alone is responsible for about 30% cases of infertility. Human follicle-stimulating hormone (hFSH) has been introduced to increase sperm concentration, spermatogonial population, or both natural or assisted pregnancy rates (PRs) in oligozoospermic subjects with normal concentrations of gonadotropins. METHODS: Fifty infertile men affected by idiopathic azoospermia were enrolled in this study, after undergoing medical history, physical and clinical examination, baseline semen parameters and hormonal plasma concentrations...
August 7, 2017: Urologia
https://www.readbyqxmd.com/read/28799257/comparison-of-costs-associated-with-substituting-culture-medium-with-saline-solution-for-follicular-flushing-during-oocyte-retrieval
#12
Dmitry Loktionov, Oladayo Oduola, Jenny Cloherty, Sharon M Warner, Nikhil Purandare
OBJECTIVES: To compare culture medium and saline solution for follicular flushing during oocyte retrieval with assisted reproductive technologies. METHODS: The present retrospective study analyzed data collected at Galway Fertility Clinic, Galway, Ireland, between January 1, 2015, and August 31, 2016; all patients attending the clinic for in vitro fertilization/intracytoplasmic sperm injection during this period were included. Data were stratified by whether follicular flushing was performed with culture medium or saline, and the oocyte yield rate, fertilization rate, embryo utilization rate, and biochemical and clinical pregnancy rates were compared between the groups...
August 11, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28795845/analysis-of-embryo-intactness-and-developmental-potential-following-slow-freezing-and-vitrification
#13
Lan Yu, Chanwei Jia, Yonglian Lan, Rui Song, Liying Zhou, Ying Li, Yu Liang, Shuyu Wang
The aim of this study was to identify the parameters that are related to intactness and developmental potential of a day 3 embryo after warming to improve the selection criteria used to cryopreserve and transfer embryos. We also sought to compare slow freezing and vitrification methods of cryopreservation and to evaluate the viability of non-intact embryos. Embryos warmed following slow freezing (n=220) or vitrification (n=522) were divided into 3 groups according to the proportion of surviving blastomeres (I<50%; II=50-99%; and III=100%)...
August 10, 2017: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/28795044/n-glycoproteomic-analysis-of-human-follicular-fluid-during-natural-and-stimulated-cycles-in-patients-undergoing-in-vitro-fertilization
#14
Hee-Joung Lim, Ae Eun Seok, Jiyou Han, Jiyeong Lee, Sungeun Lee, Hee-Gyoo Kang, Byung Heun Cha, Yunseok Yang
OBJECTIVE: Hyperstimulation methods are broadly used for in vitro fertilization (IVF) in patients with infertility; however, the side effects associated with these therapies, such as ovarian hyperstimulation syndrome (OHSS), have not been well studied. N-glycoproteomes are subproteomes used for the remote sensing of ovarian stimulation in follicular growth. Glycoproteomic variation in human follicular fluid (hFF) has not been evaluated. In this study, we aimed to identify and quantify the glycoproteomes and N-glycoproteins (N-GPs) in natural and stimulated hFF using label-free nano-liquid chromatography/electrospray ionization-quad time-of-flight mass spectrometry...
June 2017: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/28791527/impact-of-imatinib-on-the-fertility-of-male-patients-with-chronic-myelogenous-leukaemia-in-the-chronic-phase
#15
Xiaohui Chang, Lin Zhou, Xiaoxia Chen, Baoli Xu, Yubin Cheng, Shujun Sun, Meiyun Fang, Yang Xiang
BACKGROUND: Imatinib is a first-line tyrosine kinase inhibitor for treating chronic myelogenous leukaemia (CML) and has greatly improved the prognosis of this disease. An increasing number of CML patients of reproductive age are diagnosed each year, and the impact of imatinib on fertility is a major concern. Providing useful advice to these patients regarding the choice of their therapeutic treatment is very important. OBJECTIVE: This study examined the impact of imatinib on the fertility of male patients with CML in the chronic phase...
August 8, 2017: Targeted Oncology
https://www.readbyqxmd.com/read/28791262/clinical-characteristics-of-pregnancies-complicated-by-congenital-myotonic-dystrophy
#16
Cheonga Yee, Suk-Joo Choi, Soo-Young Oh, Chang-Seok Ki, Cheong-Rae Roh, Jong-Hwa Kim
OBJECTIVE: Although the conventional prevalence of myotonic dystrophy is 1:8,000, the prevalence in Korean population was recently reported as 1:1,245. With higher domestic result than expected, we aimed to investigate the clinical characteristics of pregnancies complicated by congenital myotonic dystrophy in our institution. METHODS: We have reviewed 11 paired cases of neonates diagnosed with congenital myotonic dystrophy and their mothers between July 2004 and May 2014, with clinical features including maternal history of infertility, prenatal ultrasonographic findings, and neonatal outcomes...
July 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28783590/vulvar-thermal-pattern-following-synchronization-of-estrus-is-linked-to-fertility-after-timed-artificial-insemination-in-goat
#17
Calogero Stelletta, Koray Tekin, Mehmet Borga Tirpan, Havva Alemdar, Beste Cil, Fatma Oztutar Stelletta, Kemal Tuna Olgac, Muhammed Enes Inanc, Ali Daskin
Aim of this study was to study the vulvar thermal pattern variation during the timed artificial insemination protocol in Angora goat and identify the relationship with the successful rate. Does (36 adult healthy females) were synchronized using PGF2α at the day 0, 11 days of progesterone impregnated sponges intra-vaginally, PMSG 48 h before sponges withdraw (day 11) and the intra-cervical inseminations were carried out 48 h later (Timed Artificial Insemination: TAI) with chilled semen. Vulvar (VST) and perivulvar (PST) areas were considered to evaluate the thermal pattern during the protocol at the day 0 and at the TAI using a thermo camera (E60, FLIR System)...
July 27, 2017: Theriogenology
https://www.readbyqxmd.com/read/28783553/effect-of-advanced-maternal-age-on-maternal-and-neonatal-outcomes-in-assisted-reproductive-technology-pregnancies
#18
Amirhossein Moaddab, Frank A Chervenak, Laurence B Mccullough, Haleh Sangi-Haghpeykar, Amir A Shamshirsaz, Amy Schutt, Sara E Arian, Karin A Fox, Gary A Dildy, Alireza A Shamshirsaz
OBJECTIVES: To compare maternal and neonatal outcomes between women with assisted reproductive technologies pregnancy aged <40, 40-44, 45-49, and ≥50 years. STUDY: Design In a population-level analysis study, all live births by ART identified on birth certificate between 2011 and 2014 were extracted (n=101,494) using data from the Center for Disease Control and Prevention-National Center for Health Statistics (CDC-NCHS). We investigated and compared maternal and neonatal outcomes based on conditions routinely listed on birth certificates...
July 29, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28782302/effect-of-in-vitro-selenium-supplementation-on-sperm-quality-in-asthenoteratozoospermic-men
#19
A A Ghafarizadeh, G Vaezi, M A Shariatzadeh, A A Malekirad
Sperm DNA damage, excessive oxidative stress and decrease in motility ‎may lead to low fertilisation or poor‎ assisted reproductive techniques outcomes in asthenoteratozoospermic ‎men. Selenium was considered as essential element for male reproductive functions. Selenium has important role in enzymatic process for elimination of excessive reactive oxygen species and helps to maintain membrane integrity. The aim of this study was to determine the effect of selenium supplementation on sperm quality, DNA fragmentation, mitochondrial membrane potential and membrane lipid peroxidation during sperm sampling in vitro at different times...
August 6, 2017: Andrologia
https://www.readbyqxmd.com/read/28781942/prevalence-and-determinants-of-preterm-birth-in-tehran-iran-a-comparison-between-logistic-regression-and-decision-tree-methods
#20
Payam Amini, Saman Maroufizadeh, Reza Omani Samani, Omid Hamidi, Mahdi Sepidarkish
OBJECTIVES: Preterm birth (PTB) is a leading cause of neonatal death and the second biggest cause of death in children under five years of age. The objective of this study was to determine the prevalence of PTB and its associated factors using logistic regression and decision tree classification methods. METHODS: This cross-sectional study was conducted on 4,415 pregnant women in Tehran, Iran, from July 6-21, 2015. Data were collected by a researcher-developed questionnaire through interviews with mothers and review of their medical records...
June 2017: Osong Public Health and Research Perspectives
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