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https://www.readbyqxmd.com/read/28651959/patients-with-endometriosis-have-aneuploidy-rates-equivalent-to-their-age-matched-peers-in-the-in%C3%A2-vitro-fertilization-population
#1
Caroline Juneau, Emily Kraus, Marie Werner, Jason Franasiak, Scott Morin, George Patounakis, Thomas Molinaro, Dominique de Ziegler, Richard T Scott
OBJECTIVE: To determine whether endometriosis ultimately results in an increased risk of embryonic aneuploidy. DESIGN: Retrospective cohort. SETTING: Infertility clinic. PATIENT(S): Patients participating in an in vitro fertilization (IVF) cycle from 2009-2015 using preimplantation genetic screening (PGS) who had endometriosis identified by surgical diagnosis or by ultrasound findings consistent with a persistent space-occupying disease whose sonographic appearance was consistent with endometriosis...
June 23, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28651359/altered-mirna-and-pirna-profiles-in-cumulus-cells-from-patients-with-diminished-ovarian-reserve
#2
Dawei Chen, Zhiguo Zhang, Beili Chen, Dongmei Ji, Yan Hao, Ping Zhou, Zhaolian Wei, Yunxia Cao
Diminished ovarian reserve (DOR) is defined as decreased number or quality of follicles and oocytes in a woman at childbearing age. It is estimated that up to 10% of women in the general population may suffer from DOR. The present study aims to comprehensively characterize miRNA and piRNA expression profiles in cumulus cells of DOR patients. Cumulus cells were collected from 20 women of similar chronological age who received assisted reproductive technology treatment, 10 with diminished ovarian reserve (DOR), 10 with normal ovarian reserve (NOR)...
June 23, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28651210/associations-between-perfluorinated-alkyl-acids-in-blood-and-ovarian-follicular-fluid-and-ovarian-function-in-women-undergoing-assisted-reproductive-treatment
#3
Jessica A McCoy, Jacqueline T Bangma, Jessica L Reiner, John A Bowden, John Schnorr, Michael Slowey, Thomas O'Leary, Louis J Guillette, Benjamin B Parrott
Endocrine disrupting contaminants, in combination with other environmental variables, are associated with altered reproductive health. Assisted reproductive technology (ART) procedures offer valuable opportunities to explore the connections between environmental contaminants in the ovarian microenvironment and measures of fertility, including impaired responsiveness to gonadotropins. Here, we investigate an emerging class of environmental contaminants, the perfluorinated alkyl acids (PFAAs), to determine whether ovarian contaminant levels are associated with measures of ovarian responsiveness and fertility outcomes in a South Carolina population of women undergoing ART...
June 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28649382/does-sperm-quality-and-dna-integrity-differ-in-cryopreserved-semen-samples-from-young-adult-and-aged-nellore-bulls
#4
J T Carreira, J T Trevizan, I R Carvalho, B Kipper, L H Rodrigues, C Silva, S H V Perri, J R Drevet, M B Koivisto
BACKGROUND: In humans, it is now well documented that rising paternal age is correlated with decreased sperm DNA integrity and embryonic developmental failures. On the other side of the coin, it is also reported that very young fathers such as teenagers carry an increased risk of adverse birth outcomes. These observations suggest that, at least in humans, there is an age window for optimal sperm DNA integrity. In bovine, little is known about sperm DNA quality in young bulls and how it evolves with age...
2017: Basic and Clinical Andrology
https://www.readbyqxmd.com/read/28646941/postwash-total-motile-sperm-count-should-it-be-included-as-a-standard-male-infertility-work-up
#5
Khaled Madbouly, Ahmed Isa, Mohamad Habous, Raed Almannie, Basim Abu-Rafea, Saleh Binsaleh
INTRODUCTION: Pregnancy rates after intrauterine insemination (IUI) varies greatly. We aimed to identify pre and post processing semen analysis parameters that may be predictive of successful pregnancy in couples undergoing IUI. MATERIALS AND METHODS: A retrospective study of the records of all couples underwent IUI for a 2 year period at our infertility center. Different characteristics of female subjects, pre and post processing semen parameters and treatment parameters were compared statistically...
June 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28645286/the-myths-surrounding-mild-stimulation-in-vitro-fertilization-ivf
#6
REVIEW
Raoul Orvieto, Valeria Stella Vanni, Norbert Gleicher
So-called mild controlled ovarian hyperstimulation (mCOH) has in recent years increased in popularity, claiming to be safer and more patient-friendly, while also improving in vitro fertilization (IVF) outcomes. We here challenge the International Society for Mild Approaches in Assisted Reproduction (ISMAAR) definition of mild stimulation, and especially address four fundamental issues, where our review found conventional COH (cCOH) advantageous over mCOH. They are: prevalence of severe ovarian hyperstimulation syndrome (OHSS), oocyte/embryo quality, pregnancy/live birth rates, and cost...
June 24, 2017: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/28644873/circular-rna-expression-profiling-of-human-granulosa-cells-during-maternal-aging-reveals-novel-transcripts-associated-with-assisted-reproductive-technology-outcomes
#7
Jing Cheng, Jia Huang, Suzhen Yuan, Su Zhou, Wei Yan, Wei Shen, Yun Chen, Xi Xia, Aiyue Luo, Da Zhu, Shixuan Wang
Circular RNAs (circRNAs) are a unique class of endogenous RNAs which could be used as potential diagnostic and prognostic biomarkers of many diseases. Our study aimed to investigate circRNA profiles in human granulosa cells (GCs) during maternal aging and to uncover age-related circRNA variations that potentially reflect decreased oocyte competence. CircRNAs in GCs from in vitro fertilization (IVF) patients with young age (YA, ≤ 30 years) and advanced age (AA, ≥ 38 years) were profiled by microarray, and validated in 20 paired samples...
2017: PloS One
https://www.readbyqxmd.com/read/28643569/iron-overload-directly-affecting-the-ovaries-in-a-patient-with-diamond-blackfan-anaemia-a-case-report
#8
Mariano Mascarenhas, Victoria Rawnsley, Adam Balen
Iron is a 'one-way' element and the primary point of regulation of body iron stores is at the level of intestinal iron absorption. Repeated blood transfusions for congenital anaemias bypass this regulatory checkpoint and inevitably lead to iron overload in the long-term. Iron overload causes multi-organ dysfunction of the heart, liver, pancreas and joints. It also causes reproductive toxicity primarily through its damaging effect on the anterior pituitary leading to hypogonadotrophic hypogonadism. Another less understood mechanism of reproductive toxicity is direct gonadal damage of excess free iron...
June 23, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28643503/the-use-of-morphokinetic-as-a-predictor-of-implantation
#9
Alberto Tejera, Belén Aparicio-Ruiz, Marcos Meseguer
In recent years the increased efforts intended for improving future outcomes in the laboratory have focused mostly on the search of additional markers of embryo quality to add up present embryo selection criteria. Time-lapse system involves an alternative tool in assisted reproduction techniques, being able to improve the embryo selection from a dynamic and interactive approach while standard embryo assessment implies a subjective and static morphology evaluation and consequently reducing the information gained for embryo selection, time-lapse technology adds several morphokinetic parameters, providing additional input for embryo evaluation...
June 22, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28642442/triplet-pregnancy-with-fetal-reduction-experience-in-hong-kong
#10
W T Tse, L W Law, D S Sahota, T Y Leung, Y Ky Cheng
INTRODUCTION: Triplet and higher-order multiple pregnancies are well known to be associated with increased adverse outcomes. This study reviewed the perinatal outcomes in women with a triplet pregnancy who underwent fetal reduction versus expectant management at a university hospital in Hong Kong. METHODS: This was a retrospective review of triplet pregnancies at Prince of Wales Hospital in Hong Kong from 1 January 2008 to 30 September 2014. Women carrying a triplet pregnancy were classified as having had expectant management, fetal reduction to twins, or fetal reduction to a singleton...
June 23, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28641583/prevalence-and-risk-factors-of-infertility-in-turkey-evidence-from-demographic-and-health-surveys-1993-2013
#11
Melike Sarac, Ismet Koc
The inability to have children affects couples worldwide and causes emotional and psychological distress in both men and women. Turkey is a country that lays particular emphasis on the issue of infertility, especially after experiencing a dramatic fertility decline over the last two decades. This study aimed to understand the changes in the prevalence of infertility in Turkey using three different approaches: the DHS Approach, the Constructed Approach and the Current Duration Approach. Furthermore, the factors contributing to elevated risks of infertility as derived from the Constructed Approach were investigated using four different logistic regression models...
June 23, 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/28641554/future-of-spermatogonial-stem-cell-culture-application-of-nanofiber-scaffolds
#12
Azar Shams, Neda Eslahi, Mansoureh Movahedin, Fariborz Izadyar, Hamidreza Asgari, Morteza Koruji
The spermatogonial stem cells (SSCs) are unique in mammals because they can transmit genetic information from generation to generation and it is of significant importance. In testes, Sertoli cells, peritubular myoid cells, Leydig cells and other interstitial cells contribute to the spermatogonial stem cell "niche". So, creation of niche in in vitro condition that mimics in vivo environment is essential to maintain functional characteristic of SSCs. Nanofiber matrices mimic the architecture and size scale of the natural extracellular matrix (ECM)...
June 22, 2017: Current Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28639180/initial-maternal-serum-human-chorionic-gonadotropin-levels-in-pregnancies-achieved-after-assisted-reproductive-technology-are-higher-after-preimplantation-genetic-screening-and-after-frozen-embryo-transfer-a-retrospective-cohort
#13
Elie Hobeika, Sonali Singh, Shaveta Malik, Eric S Knochenhauer, Michael L Traub
PURPOSE: Few published articles have compared initial hCG values across all different types of ART cycles, including cycles with fresh or frozen embryo transfer. No articles have compared initial hCG values in cycles utilizing preimplantation genetic screening (PGS). The purpose of this study is to compare initial hCG values after fresh embryo transfer, frozen embryo transfer, and after PGS. METHODS: This was a single-center retrospective cohort study at an academically affiliated private IVF center...
June 21, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28638443/dosage-compensation-and-sex-specific-epigenetic-landscape-of-the-x-chromosome-in-the-pea-aphid
#14
Gautier Richard, Fabrice Legeai, Nathalie Prunier-Leterme, Anthony Bretaudeau, Denis Tagu, Julie Jaquiéry, Gaël Le Trionnaire
BACKGROUND: Heterogametic species display a differential number of sex chromosomes resulting in imbalanced transcription levels for these chromosomes between males and females. To correct this disequilibrium, dosage compensation mechanisms involving gene expression and chromatin accessibility regulations have emerged throughout evolution. In insects, these mechanisms have been extensively characterized only in Drosophila but not in insects of agronomical importance. Aphids are indeed major pests of a wide range of crops...
2017: Epigenetics & Chromatin
https://www.readbyqxmd.com/read/28638213/comment-on-disability-psychiatric-symptoms-and-quality-of-life-in-infertile-women-a-cross-sectional-study-in-turkey
#15
EDITORIAL
Salvatore Giovanni Vitale, Valentina Lucia La Rosa, Agnese Maria Chiara Rapisarda, Antonio Simone Laganà
The aim of this work is to comment on the study about disability, psychiatric symptoms and quality of life in infertile women of Turkey that was published in this Journal. We suggest that future studies use larger samples, consider the influence of factors such as cause of infertility and assisted reproductive techniques (ARTs) and, last but not least, exclude other comorbidities which may influence the data analysis.
December 25, 2016: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28638125/psychoanalytic-aspects-of-assisted-reproductive-technology-edited-by-mali-mann-karnac-books-london-u-k-2014-144pp
#16
Christie M Platt
No abstract text is available yet for this article.
September 2016: American Journal of Psychoanalysis
https://www.readbyqxmd.com/read/28637085/successful-delivery-derived-from-cryopreserved-rare-human-spermatozoa-with-novel-cryopiece
#17
J Sun, W Chen, L Zhou, J Hu, Z Li, Z Zhang, Y Wu
Herein, we report the clinical outcomes following intracytoplasmic sperm injection (ICSI) with cryopiece cryopreserved rare human spermatozoa from severe male factor infertility patients. We established a novel cryopiece system on the basis of previous studies. In this study, 126 spermatozoa from four patients with non-obstructiveazoospermia (NOA) or severe oligozoospermia were stored in cryopiece and then thawed on the day of the oocyte retrieval, 88 (83%) spermatozoa were recovered with a 47.5% (38 of 80) motile rate...
June 21, 2017: Andrology
https://www.readbyqxmd.com/read/28635413/the-high-responder-a-review-of-pathophysiology-and-outcomes-during-ivf-treatment
#18
Mariano Mascarenhas, Adam H Balen
This review attempts to summarize the known literature on high responders to ovarian stimulation during assisted reproductive techniques (ART). Response to gonadotrophins is subject to significant interindividual and intercycle variation, thus carrying a risk of high response or poor response to ovarian stimulation regimens. The main risk for high responders is the development of ovarian hyperstimulation syndrome (OHSS) which is associated with significant morbidity. Hence, the definition of high responders in the literature has primarily focussed on risk factors for OHSS...
February 28, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28635408/assisted-reproductive-technologies-and-the-iranian-community-attitude-towards-infertility
#19
Aliyar Ahmadi, Sara Bamdad
Since the late 1990s, assisted reproductive technologies (ARTs) have been legitimized in Iran through an official religious endorsement. Iran, under the dominant authority of the Shia sect, is now the most enthusiastic adopter of ARTs in the Muslim world, permitting all forms of treatments, including third party donation. This study examined the public perception of assisted conception and its influence on the adoption of these methods in Iran. The study was questionnaire-based and conducted in 2012 in Shiraz, the most populated city in the south of Iran...
February 7, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28634246/assisted-reproductive-techniques-and-risk-of-beckwith-wiedemann-syndrome
#20
Alessandro Mussa, Cristina Molinatto, Flavia Cerrato, Orazio Palumbo, Massimo Carella, Giuseppina Baldassarre, Diana Carli, Clementina Peris, Andrea Riccio, Giovanni Battista Ferrero
BACKGROUND AND OBJECTIVES: The emerging association of assisted reproductive techniques (ART) with imprinting disorders represents a major issue in the scientific debate on infertility treatment and human procreation. We studied the prevalence of Beckwith-Wiedemann syndrome (BWS) in children conceived through ART to define the specific associated relative risk. METHODS: Patients with BWS born in Piemonte, Italy, were identified and matched with the general demographic data and corresponding regional ART registry...
June 20, 2017: Pediatrics
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