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Heat related emergencies

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https://www.readbyqxmd.com/read/29335771/risk-perception-of-heat-waves-and-its-spatial-variation-in-nanjing-china
#1
Lei Huang, Qianqi Yang, Jie Li, Jin Chen, Ruoying He, Can Zhang, Kai Chen, Steven Guanpeng Dong, Yang Liu
The intensity, frequency, and duration of heat waves are expected to increase with climate change. In this study, we found a significant difference of public perceived effects of heat waves and trust in government among urban, suburban, and rural districts. Rural residents had a significant higher effect perception than urbanites and also showed stronger willingness to have medical insurance or regular physical examinations. Meanwhile, suburban residents had the lowest trust perception in government among these three districts, which may be due to suburban districts' unique social structure and complex social issues...
December 13, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/29306816/-you-got-to-love-rosin-solventless-dabs-pure-clean-natural-medicine-exploring-twitter-data-on-emerging-trends-in-rosin-tech-marijuana-concentrates
#2
Francois R Lamy, Raminta Daniulaityte, Mussah Zatreh, Ramzi W Nahhas, Amit Sheth, Silvia S Martins, Edward W Boyer, Robert G Carlson
BACKGROUND: "Rosin tech" is an emerging solventless method consisting in applying moderate heat and constant pressure on marijuana flowers to prepare marijuana concentrates referred to as "rosin." This paper explores rosin concentrate-related Twitter data to describe tweet content and analyze differences in rosin-related tweeting across states with varying cannabis legal statuses. METHOD: English language tweets were collected between March 15, 2015 and April 17, 2017, using Twitter API...
December 27, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29304777/heat-and-emergency-room-admissions-in-the-netherlands
#3
Joris Adriaan Frank van Loenhout, Tefera Darge Delbiso, Anna Kiriliouk, Jose Manuel Rodriguez-Llanes, Johan Segers, Debarati Guha-Sapir
BACKGROUND: Due to a global warming-related increase in heatwaves, it is important to obtain detailed understanding of the relationship between heat and health. We assessed the relationship between heat and urgent emergency room admissions in the Netherlands. METHODS: We collected daily maximum temperature and relative humidity data over the period 2002-2007. Daily urgent emergency room admissions were divided by sex, age group and disease category. We used distributed lag non-linear Poisson models, estimating temperature-admission associations...
January 5, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29303303/entropy-production-and-fluctuation-theorems-for-active-matter
#4
Dibyendu Mandal, Katherine Klymko, Michael R DeWeese
Active biological systems reside far from equilibrium, dissipating heat even in their steady state, thus requiring an extension of conventional equilibrium thermodynamics and statistical mechanics. In this Letter, we have extended the emerging framework of stochastic thermodynamics to active matter. In particular, for the active Ornstein-Uhlenbeck model, we have provided consistent definitions of thermodynamic quantities such as work, energy, heat, entropy, and entropy production at the level of single, stochastic trajectories and derived related fluctuation relations...
December 22, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29303196/biodegradable-moox-nanoparticles-with-efficient-near-infrared-photothermal-and-photodynamic-synergetic-cancer-therapy-at-the-second-biological-window
#5
Wenyan Yin, Tao Bao, Xiao Zhang, Qin Gao, Jie Yu, Xinghua Dong, Liang Yan, Zhanjun Gu, Yuliang Zhao
Near-infrared (NIR) laser induced phototherapy has been considered as a noninvasive option for cancer therapy. Herein, we report plasmonic PEGylated molybdenum oxide nanoparticles (PEG-MoOx NPs) that were synthesized by using a facile hydrothermal method. The PEG-MoOx NPs exhibit broad absorption at the NIR biological window and remarkable photothermal conversion ability in the first (808 nm) and the second (1064 nm) windows. Moreover, the biocompatible PEG-MoOx NPs exhibit effective cellular uptake and could be eliminated gradually from the liver and spleen in mice...
January 5, 2018: Nanoscale
https://www.readbyqxmd.com/read/29289598/why-should-neuroscientists-worry-about-iron-the-emerging-role-of-ferroptosis-in-the-pathophysiology-of-neuroprogressive-diseases
#6
REVIEW
Gerwyn Morris, Michael Berk, André F Carvalho, Michael Maes, Adam J Walker, Basant K Puri
Ferroptosis is a unique form of programmed death, characterised by cytosolic accumulation of iron, lipid hydroperoxides and their metabolites, and effected by the fatal peroxidation of polyunsaturated fatty acids in the plasma membrane. It is a major driver of cell death in neurodegenerative neurological diseases. Moreover, cascades underpinning ferroptosis could be active drivers of neuropathology in major psychiatric disorders. Oxidative and nitrosative stress can adversely affect mechanisms and proteins governing cellular iron homeostasis, such as the iron regulatory protein/iron response element system, and can ultimately be a source of abnormally high levels of iron and a source of lethal levels of lipid membrane peroxidation...
December 28, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29276638/the-effect-of-various-hot-environments-on-physiological-responses-and-information-processing-performance-following-firefighting-activities-in-a-smoke-diving-room
#7
Rasoul Hemmatjo, Majid Motamedzade, Mohsen Aliabadi, Omid Kalatpour, Maryam Farhadian
Background: Fire service workers often implement multiple duties in the emergency conditions, with such duties being mostly conducted in various ambient temperatures. Methods: The aim of the current study was to assess the firefighters' physiological responses, information processing, and working memory prior to and following simulated firefighting activities in three different hot environments. Seventeen healthy male firefighters performed simulated firefighting tasks in three separate conditions, namely (1) low heat (LH; 29-31°C, 55-60% relative humidity), (2) moderate heat (MH; 32-34°C, 55-60% relative humidity), and (3) severe heat (SH; 35-37°C, 55-60% relative humidity)...
December 2017: Safety and Health At Work
https://www.readbyqxmd.com/read/29243038/what-performance-analysts-need-to-know-about-research-trends-in-association-football-2012-2016-a-systematic-review
#8
REVIEW
Hugo Sarmento, Filipe Manuel Clemente, Duarte Araújo, Keith Davids, Allistair McRobert, António Figueiredo
BACKGROUND: Evolving patterns of match analysis research need to be systematically reviewed regularly since this area of work is burgeoning rapidly and studies can offer new insights to performance analysts if theoretically and coherently organized. OBJECTIVE: The purpose of this paper was to conduct a systematic review of published articles on match analysis in adult male football, identify and organize common research topics, and synthesize the emerging patterns of work between 2012 and 2016, according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines...
December 14, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29239735/burns-centre-and-fire-services-what-information-can-be-exchanged-to-manage-the-burn-patient
#9
O Pujji, B Nizar, J Bechar, D North, S Jeffery
AIM: To describe the experience of using a "Burns Extrication Form" at a regional Burns Centre. Communication between the fire services and burns team previously has been regarded as poor. Significant information is collected by the fire services at the scene and this can aid the management of the patient. METHODS: The Burns Extrication Form was devised to provide a clear framework of communication between the two services. Information regarding time frames, exposure to heat & smoke, fire loading (potential severity of a fire in a given space by measuring amount of combustible material in confined space), building construction, chemicals involved is passed to the medical team through this form through a National Health Service mailbox...
November 24, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29220364/an-attempt-to-interpret-a-biochemical-mechanism-of-c4-photosynthetic-thermo-tolerance-under-sudden-heat-shock-on-detached-leaf-in-elevated-co2-grown-maize
#10
Mingnan Qu, James A Bunce, Richard C Sicher, Xiaocen Zhu, Bo Gao, Genyun Chen
Detached leaves at top canopy structures always experience higher solar irradiance and leaf temperature under natural conditions. The ability of tolerance to high temperature represents thermotolerance potential of whole-plants, but was less of concern. In this study, we used a heat-tolerant (B76) and a heat-susceptible (B106) maize inbred line to assess the possible mitigation of sudden heat shock (SHS) effects on photosynthesis (PN) and C4 assimilation pathway by elevated [CO2]. Two maize lines were grown in field-based open top chambers (OTCs) at ambient and elevated (+180 ppm) [CO2]...
2017: PloS One
https://www.readbyqxmd.com/read/29219089/health-impacts-of-climate-change-and-health-and-social-inequalities-in-the-uk
#11
REVIEW
Jouni Paavola
This article examines how social and health inequalities shape the health impacts of climate change in the UK, and what the implications are for climate change adaptation and health care provision. The evidence generated by the other articles of the special issue were interpreted using social justice reasoning in light of additional literature, to draw out the key implications of health and social inequalities for health outcomes of climate change. Exposure to heat and cold, air pollution, pollen, food safety risks, disruptions to access to and functioning of health services and facilities, emerging infections and flooding are examined as the key impacts of climate change influencing health outcomes...
December 5, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29209828/regulation-of-immunometabolism-in-adipose-tissue
#12
REVIEW
Manju Kumari, Joerg Heeren, Ludger Scheja
Adipose tissue has emerged as a major player in driving obesity-related inflammatory response. In obesity, chronic infiltration of macrophages in adipose tissue mediates local and systemic inflammation and acts as a key contributor to insulin resistance. In the past few years, adipose tissue plasticity and remodeling capacity has been studied extensively to develop therapeutic targets to combat obesity and related metabolic dysfunction. Progress in understanding the potential of adipocytes and contribution of macrophages and other immune cells to control immunometabolism in disease state has provided us new potential intervention targets to explore such as the formation of heat-producing beige adipocytes in white adipose tissue and the polarization of macrophages from an inflammatory toward an anti-inflammatory phenotype...
December 5, 2017: Seminars in Immunopathology
https://www.readbyqxmd.com/read/29202454/fentanyl-related-designer-drugs-w-18-and-w-15-lack-appreciable-opioid-activity-in-vitro-and-in-vivo
#13
Xi-Ping Huang, Tao Che, Thomas J Mangano, Valerie Le Rouzic, Ying-Xian Pan, Michael D Cameron, Michael H Baumann, Gavril W Pasternak, Bryan L Roth
W-18 (4-chloro-N-[1-[2-(4-nitrophenyl)ethyl]-2-piperidinylidene]-benzenesulfonamide) and W-15 (4-chloro-N-[1-(2-phenylethyl)-2-piperidinylidene]-benzenesulfonamide) represent two emerging drugs of abuse chemically related to the potent opioid agonist fentanyl (N-(1-(2-phenylethyl)-4-piperidinyl)-N-phenylpropanamide). Here, we describe the comprehensive pharmacological profiles of W-18 and W-15, as examination of their structural features predicted that they might lack opioid activity. We found W-18 and W-15 to be without detectible activity at μ, δ, κ, and nociception opioid receptors in a variety of assays...
November 16, 2017: JCI Insight
https://www.readbyqxmd.com/read/29196618/the-kalancho%C3%A3-genome-provides-insights-into-convergent-evolution-and-building-blocks-of-crassulacean-acid-metabolism
#14
Xiaohan Yang, Rongbin Hu, Hengfu Yin, Jerry Jenkins, Shengqiang Shu, Haibao Tang, Degao Liu, Deborah A Weighill, Won Cheol Yim, Jungmin Ha, Karolina Heyduk, David M Goodstein, Hao-Bo Guo, Robert C Moseley, Elisabeth Fitzek, Sara Jawdy, Zhihao Zhang, Meng Xie, James Hartwell, Jane Grimwood, Paul E Abraham, Ritesh Mewalal, Juan D Beltrán, Susanna F Boxall, Louisa V Dever, Kaitlin J Palla, Rebecca Albion, Travis Garcia, Jesse A Mayer, Sung Don Lim, Ching Man Wai, Paul Peluso, Robert Van Buren, Henrique Cestari De Paoli, Anne M Borland, Hong Guo, Jin-Gui Chen, Wellington Muchero, Yanbin Yin, Daniel A Jacobson, Timothy J Tschaplinski, Robert L Hettich, Ray Ming, Klaus Winter, James H Leebens-Mack, J Andrew C Smith, John C Cushman, Jeremy Schmutz, Gerald A Tuskan
Crassulacean acid metabolism (CAM) is a water-use efficient adaptation of photosynthesis that has evolved independently many times in diverse lineages of flowering plants. We hypothesize that convergent evolution of protein sequence and temporal gene expression underpins the independent emergences of CAM from C3 photosynthesis. To test this hypothesis, we generate a de novo genome assembly and genome-wide transcript expression data for Kalanchoë fedtschenkoi, an obligate CAM species within the core eudicots with a relatively small genome (~260 Mb)...
December 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/29190034/the-role-of-%C3%AE-b-crystallin-in-skeletal-and-cardiac-muscle-tissues
#15
REVIEW
Ivan Dimauro, Ambra Antonioni, Neri Mercatelli, Daniela Caporossi
All organisms and cells respond to various stress conditions such as environmental, metabolic, or pathophysiological stress by generally upregulating, among others, the expression and/or activation of a group of proteins called heat shock proteins (HSPs). Among the HSPs, special attention has been devoted to the mutations affecting the function of the αB-crystallin (HSPB5), a small heat shock protein (sHsp) playing a critical role in the modulation of several cellular processes related to survival and stress recovery, such as protein degradation, cytoskeletal stabilization, and apoptosis...
November 30, 2017: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/29155564/mass-spectrometry-imaging-a-review-of-emerging-advancements-and-future-insights
#16
Amanda R Buchberger, Kellen DeLaney, Jillian Johnson, Lingjun Li
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations into the spatial distribution of molecular species in a variety of samples. It has the capability to image thousands of molecules, such as metabolites, lipids, peptides, proteins, and glycans, in a single experiment without labeling. The combination of information gained from mass spectrometry (MS) and visualization of spatial distributions in thin sample sections makes this a valuable chemical analysis tool useful for biological specimen characterization...
November 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29153160/a-100-year-review-calf-nutrition-and-management
#17
A F Kertz, T M Hill, J D Quigley, A J Heinrichs, J G Linn, J K Drackley
The first calf paper, published in the May 1919 issue of the Journal of Dairy Science (JDS), described factors affecting birth body weight of different breeds of calves. Other studies were done on nonmilk ingredients, growth charts were developed, and early weaning was followed to conserve milk fed to calves. Calf papers did not report use of statistics to control or record variation or to determine whether treatment means were different. Many experiments were more observational than comparative. Typically fewer than 5 calves, and sometimes 1 or 2 calves, were used per treatment...
December 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29146008/heat-and-pregnancy-related-emergencies-risk-of-placental-abruption-during-hot-weather
#18
Siyi He, Tom Kosatsky, Audrey Smargiassi, Marianne Bilodeau-Bertrand, Nathalie Auger
INTRODUCTION: Outdoor heat increases the risk of preterm birth and stillbirth, but the association with placental abruption has not been studied. Placental abruption is a medical emergency associated with major morbidity and mortality in pregnancy. We determined the relationship between ambient temperature and risk of placental abruption in warm seasons. MATERIAL AND METHODS: We performed a case-crossover analysis of 17,172 women whose pregnancies were complicated by placental abruption in Quebec, Canada from May to October 1989-2012...
November 13, 2017: Environment International
https://www.readbyqxmd.com/read/29143414/central-pain-processing-in-drug-na%C3%A3-ve-pain-free-patients-with-parkinson-s-disease
#19
Alessandro Tessitore, Antonio Russo, Rosa De Micco, Michele Fratello, Giuseppina Caiazzo, Alfonso Giordano, Mario Cirillo, Gioacchino Tedeschi, Fabrizio Esposito
BACKGROUND: Despite its clinical relevance, the pathophysiology of pain in Parkinson's disease (PD) is still largely unknown, and both central and peripheral mechanisms have been invoked. OBJECTIVES: To investigate whether central pain processing is altered in "drug-naive" pain-free PD (dnPD) patients. METHODS: Using event-related functional MRI (fMRI), functional response to forearm heat stimulation (FHS) at two different intensities (41°C and 53°C) was investigated in 20 pain-free dnPD patients, compared with 18 healthy controls (HCs)...
November 15, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29131171/application-of-spatially-modulated-near-infrared-structured-light-to-study-changes-in-optical-properties-of-mouse-brain-tissue-during-heatstress
#20
Oren Shaul, Michal Fanrazi-Kahana, Omri Meitav, Gad A Pinhasi, David Abookasis
Heat stress (HS) is a medical emergency defined by abnormally elevated body temperature that causes biochemical, physiological, and hematological changes. The goal of the present research was to detect variations in optical properties (absorption, reduced scattering, and refractive index coefficients) of mouse brain tissue during HS by using near-infrared (NIR) spatial light modulation. NIR spatial patterns with different spatial phases were used to differentiate the effects of tissue scattering from those of absorption...
November 10, 2017: Applied Optics
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