keyword
MENU ▼
Read by QxMD icon Read
search

aggregation

keyword
https://www.readbyqxmd.com/read/28647588/environmentally-relevant-concentrations-of-al-iii-and-fe-iii-cations-induce-aggregation-of-free-dna-by-complexation-with-phosphate-group
#1
Chao Qin, Fuxing Kang, Wei Zhang, Weijun Shou, Xiaojie Hu, Yanzheng Gao
Environmental persistence of free DNA is influenced by its complexation with other chemical species and its aggregation mechanisms. However, it is not well-known how naturally-abundant metal ions, e.g., Al(III) and Fe(III), influence DNA aggregation. This study investigated aggregation behaviors of model DNA from salmon testes as influenced by metal cations, and elucidated the predominant mechanism responsible for DNA aggregation. Compared to monovalent (K(+) and Na(+)) and divalent (Ca(2+) and Mg(2+)) cations, Al(III) and Fe(III) species in aqueous solution caused rapid DNA aggregations...
June 18, 2017: Water Research
https://www.readbyqxmd.com/read/28647523/thermal-aggregation-of-human-immunoglobulin-g-in-arginine-solutions-contrasting-effects-of-stabilizers-and-destabilizers
#2
Shunsuke Yoshizawa, Tsutomu Arakawa, Kentaro Shiraki
Arginine is widely used as aggregation suppressor of proteins in biotechnology and pharmaceutics. However, why the effect of arginine depends on the types of proteins and stresses, including monoclonal antibodies, is still unclear. Here we investigated the precise processes of the thermal aggregation of human immunoglobulin G (IgG) in the presence of additives. As expected, arginine was the best additive to suppress the formation of insoluble aggregates during heat treatment, though it was unable to preserve the monomer content...
June 21, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28647519/is-sarcopenia-associated-with-an-increased-risk-of-all-cause-mortality-and-functional-disability
#3
George A Kelley, Kristi S Kelley
BACKGROUND: While a recent meta-analysis of observational studies reported a statistically significant association between sarcopenia and both all-cause mortality and functional decline, a recently developed inverse heterogeneity (IVhet) model has been shown to be more valid than the traditional random-effects model used. OBJECTIVE: The objective of this short report was to use a previous meta-analysis to compare the two approaches. METHODS: Aggregate data meta-analysis of prospective observational studies conducted in any setting...
June 21, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28647348/pivotal-role-of-lesional-and-perilesional-t-b-lymphocytes-in-pemphigus-pathogenesis
#4
Huijie Yuan, Shengru Zhou, Zhicui Liu, Weiting Cong, Xiaochun Fei, Weihong Zeng, Haiqin Zhu, Renchao Xu, Ying Wang, Jie Zheng, Meng Pan
Pemphigus is a skin and mucosal membrane-targeting autoimmune bullous disease. Previous studies have demonstrated that circulating anti-desmoglein1/3 antibodies are pathogenic and mediate blister formation. However, the role of infiltrated immune cells in the lesional skin has not been fully investigated. In this study we showed that there existed a large number of B, T lymphocytes and plasma cells in the skin lesions by immunohistochemistry and immunofluorescence staining. In addition, a significantly increased number of Dsg1 and Dsg3-specific B cells could be identified by flow cytometric analysis or ELISPOT assay...
June 21, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28647330/effect-of-high-hydrostatic-pressure-treated-skim-milk-on-permeate-flux-and-fouling-during-ultrafiltration
#5
Mathilde Leu, Alice Marciniak, Julien Chamberland, Yves Pouliot, Laurent Bazinet, Alain Doyen
Ultrafiltration (UF) is largely used in the dairy industry to generate milk and whey protein concentrate for standardization of milk or production of dairy ingredients. Recently, it was demonstrated that high hydrostatic pressure (HHP) extended the shelf life of milk and improved rennet coagulation and cheese yield. Pressurization also modified casein micelle size distribution and promoted aggregation of whey proteins. These changes are likely to affect UF performance. Consequently, this study will determine the effect of skim milk pressurization (300 and 600 MPa, 5 min) on UF performance in terms of permeate flux decline and fouling...
June 21, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28647329/structural-changes-induced-by-high-pressure-processing-in-micellar-casein-and-milk-protein-concentrates
#6
Lee Cadesky, Markus Walkling-Ribeiro, Kyle T Kriner, Mukund V Karwe, Carmen I Moraru
Reconstituted micellar casein concentrates and milk protein concentrates of 2.5 and 10% (wt/vol) protein concentration were subjected to high-pressure processing at pressures from 150 to 450 MPa, for 15 min, at ambient temperature. The structural changes induced in milk proteins by high-pressure processing were investigated using a range of physical, physicochemical, and chemical methods, including dynamic light scattering, rheology, mid-infrared spectroscopy, scanning electron microscopy, proteomics, and soluble mineral analyses...
June 21, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28647220/investigation-of-zinc-recovery-by-hydrogen-reduction-assisted-pyrolysis-of-alkaline-and-zinc-carbon-battery-waste
#7
Burçak Ebin, Martina Petranikova, Britt-Marie Steenari, Christian Ekberg
Zinc (Zn) recovery from alkaline and zinc-carbon (Zn-C) battery waste were studied by a laboratory scale pyrolysis process at a reaction temperature of 950°C for 15-60min residence time using 5%H2(g)-N2(g) mixture at 1.0L/min gas flow rate. The effect of different cooling rates on the properties of pyrolysis residue, manganese oxide particles, were also investigated. Morphological and structural characterization of the produced Zn particles were performed. The battery black mass was characterized with respect to the properties and chemical composition of the waste battery particles...
June 21, 2017: Waste Management
https://www.readbyqxmd.com/read/28647150/ospar-standard-method-and-software-for-statistical-analysis-of-beach-litter-data
#8
Marcus Schulz, Willem van Loon, David M Fleet, Paul Baggelaar, Eit van der Meulen
The aim of this study is to develop standard statistical methods and software for the analysis of beach litter data. The optimal ensemble of statistical methods comprises the Mann-Kendall trend test, the Theil-Sen slope estimation, the Wilcoxon step trend test and basic descriptive statistics. The application of Litter Analyst, a tailor-made software for analysing the results of beach litter surveys, to OSPAR beach litter data from seven beaches bordering on the south-eastern North Sea, revealed 23 significant trends in the abundances of beach litter types for the period 2009-2014...
June 21, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28647006/a-meta-analysis-of-gaze-differences-to-social-and-nonsocial-information-between-individuals-with-and-without-autism
#9
REVIEW
Thomas W Frazier, Mark Strauss, Eric W Klingemier, Emily E Zetzer, Antonio Y Hardan, Charis Eng, Eric A Youngstrom
OBJECTIVE: Numerous studies have identified abnormal gaze in individuals with autism. However, only some findings have been replicated, the magnitude of effects is unclear, and the pattern of gaze differences across stimuli remains poorly understood. To address these gaps, a comprehensive meta-analysis of autism eye-tracking studies was conducted. METHOD: PubMed and a manual search of 1,132 publications were used to identify studies comparing looking behavior to social and/or nonsocial stimuli between individuals with autism and controls...
July 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28646766/gaps-in-aquatic-toxicological-studies-of-microplastics
#10
REVIEW
Ali Karami
The contamination of aquatic environments with microplastics (MPs) has spurred an unprecedented interest among scientific communities to investigate their impacts on biota. Despite the rapid growth in the number of studies on the aquatic toxicology of MPs, controversy over the fate and biological impacts of MPs is increasingly growing mainly due to the absence of standardized laboratory bioassays. Given the complex features of MPs, such as the diversity of constituent polymers, additives, shapes and sizes, as well as continuous changes in the particle buoyancy as a result of fouling and defouling processes, it is necessary to modify conventional bioassay protocols before employing them for MP toxicity testings...
June 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28646761/regulation-on-the-aggregation-induced-emission-aie-of-dna-templated-silver-nanoclusters-by-bsa-and-its-hydrolysates
#11
Wei-Xian Wang, Yuqing Wu, Hong-Wei Li
The aggregation-induced emission (AIE) phenomenon of the metal nanoclusters (NCs) has been discovered quite recently, which is considered to be creative to improve the optical properties of NCs upon ligand aggregation. In the present study, we report an AIE system for double-stranded DNA-templated silver nanoclusters (AgNCs-dsDNA) by using bovine serum albumin (BSA) in solution, which induce a moderate emission enhancement of AgNCs (5-fold) and a blue-shift through a loosen interaction. In addition, significant luminescence enhancement (30-fold) is further stimulated by the addition of digestive enzyme to the system by altering the surface structure of the aggregated particles...
June 10, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28646758/thermo-responsive-diblock-and-triblock-cationic-copolymers-at-the-silica-aqueous-interface-a-qcm-d-and-afm-study
#12
Saeed Zajforoushan Moghaddam, Kaizheng Zhu, Bo Nyström, Esben Thormann
The properties of synthesized diblock poly(N-isopropylacrylamide)-poly((3-acrylamidopropyl)trimethylammonium chloride) and triblock methoxy-poly(ethylene glycol)-poly(N-isopropylacrylamide)-poly((3-acrylamidopropyl)trimethylammonium chloride) cationic copolymers at the silica/aqueous interface are investigated using quartz crystal microbalance with dissipation monitoring (QCM-D) and atomic force microscopy (AFM). Moreover, dynamic light scattering is employed to assess the copolymers in terms of the hydrodynamic size and interchain aggregation...
June 15, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28646715/understanding-the-prevalence-of-lifetime-abstinence-from-alcohol-an-ecological-study
#13
Charlotte Probst, Jakob Manthey, Jürgen Rehm
BACKGROUND: The level of alcohol consumption and related burden in a country are strongly impacted by the prevalence of abstinence from alcohol use. The objective of this study was to characterize the association of lifetime abstinence from alcohol use with economic wealth (as measured in the gross domestic product [GDP]) and Muslim religion on a country level. METHODS: An ecological study was performed using aggregate data of 183 countries for the year 2010. Lifetime abstinence among men and women was predicted using fractional response regression models with the natural logarithm of GDP-PPP (purchasing power parity) and the proportion of Muslim population as predictors...
June 15, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28646617/melanoma-associated-grm3-variants-dysregulate-melanosome-trafficking-and-camp-signaling
#14
Ana Neto, Craig J Ceol
Large-scale sequencing studies have revealed several genes that are recurrently mutated in melanomas. To annotate the melanoma genome we have expressed tumor-associated variants of these genes in zebrafish and characterized their effects on melanocyte development and function. Here, we describe expression of tumor-associated variants of the recurrently-mutated metabotropic glutamate receptor 3 (GRM3) gene. Unlike wild-type GRM3, tumor-associated GRM3 variants disrupted trafficking of melanosomes, causing their aggregation in the cell body...
June 24, 2017: Pigment Cell & Melanoma Research
https://www.readbyqxmd.com/read/28646311/removal-of-arsenic-iii-v-by-a-granular-mn-oxide-doped-al-oxide-adsorbent-surface-characterization-and-performance
#15
Kun Wu, Jin Zhang, Bing Chang, Ting Liu, Furong Zhang, Pengkang Jin, Wendong Wang, Xiaochang Wang
In order to remove arsenic (As) from contaminated water, granular Mn-oxide-doped Al oxide (GMAO) was fabricated using the compression method with the addition of organic binder. The analysis results of XRD, SEM, and BET indicated that GMAO was microporous with a large specific surface area of 54.26 m(2/)g, and it was formed through the aggregation of massive Al/Mn oxide nanoparticles with an amorphous pattern. EDX, mapping, FTIR, and XPS results showed the uniform distribution of Al/Mn elements and numerous hydroxyl groups on the adsorbent surface...
June 23, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28646192/effect-of-h2o-adsorption-on-negative-differential-conductance-behavior-of-single-junction
#16
Zong-Liang Li, Xiao-Hua Yi, Ran Liu, Jun-Jie Bi, Huan-Yan Fu, Guang-Ping Zhang, Yu-Zhi Song, Chuan-Kui Wang
Large negative differential conductance (NDC) at lower bias regime is a very desirable functional property for single molecular device. Due to the non-conjugated segment separating two conjugated branches, the single thiolated arylethynylene molecule with 9,10-dihydroanthracene core (denoted as TADHA) presents excellent NDC behavior in lower bias regime. Based on the ab initio calculation and non-equilibrium Green's function formalism, the NDC behavior of TADHA molecular device and the H2O-molecule-adsorption effects are studied systematically...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28645981/work-related-psychosocial-factors-and-onset-of-metabolic-syndrome-among-workers-a-systematic-review-and-meta-analysis-protocol
#17
Asuka Sakuraya, Kazuhiro Watanabe, Norito Kawakami, Kotaro Imamura, Emiko Ando, Yumi Asai, Hisashi Eguchi, Yuka Kobayashi, Norimitsu Nishida, Hideaki Arima, Akihito Shimazu, Akizumi Tsutsumi
INTRODUCTION: Metabolic syndrome is an important public health target because of its high prevalence worldwide. Work-related psychosocial factors have been identified as determinants of metabolic syndrome components. However, there have been no systematic reviews or meta-analyses conducted to evaluate the relationship between work-related psychosocial factors and metabolic syndrome as an aggregated cluster. The aim of this study is to examine this association from published prospective studies...
June 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645780/salvia-miltiorrhiza-bunge-danshen-extract-attenuates-permanent-cerebral-ischemia-through-inhibiting-platelet-activation-in-rats
#18
Yu-Xiang Fei, Si-Qi Wang, Li-Jian Yang, Yan-Ying Qiu, Yi-Ze Li, Wen-Yuan Liu, Tao Xi, Wei-Rong Fang, Yun-Man Li
ETHNOPHARMACOLOGICAL RELEVANCE: Danshen is a crude herbal drug isolated from dried roots of Salvia miltiorrhiza Bunge. This plant is widely used in oriental medicine for the treatment of cardiovascular and cerebrovascular diseases. The supercritical CO2 extract from Danshen (SCED) (57.85%, 5.67% and 4.55% for tanshinone IIA, tanshinone I and cryptotanshinone respectively) was studied in this article, whose potential molecular mechanism remains unclear, especially in anti-thrombosis. AIM OF THE STUDY: The present study was designed to observe the protective effect of SCED on ischemic stroke in rats and to explore the underlying anti-thrombosis mechanism...
June 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28645680/collection-processing-and-freezing-of-equine-bone-marrow-cells
#19
Fernanda Z Bastos, Fernanda C M Barussi, Thasla F Santi, Bianca P Vieira, Alexandra C Senegaglia, Fernanda F Cruz, Pedro V Michelotto
There is no consensus on aspects of equine bone marrow collection and processing. The study aimed to describe the collection of large volumes of bone marrow from horses of advanced age, with emphasis on bone marrow mononuclear cells (BMMCs) recovery and viability after cryopreservation. Fourteen horses, aged 3-24 years, were divided into three experiments. E1 studied the feasibility of collecting 200 mL from the sternums of horses of advanced age; E2 examined the number of cells obtained from the first and last syringe of each puncture; and E3 investigated the influence of heparin concentration on the prevention of cell aggregation, and cell viability after freezing in liquid nitrogen...
June 20, 2017: Cryobiology
https://www.readbyqxmd.com/read/28645535/data-security-and-privacy-in-apps-for-dementia-an-analysis-of-existing-privacy-policies
#20
Lisa Rosenfeld, John Torous, Ipsit V Vahia
INTRODUCTION: Despite tremendous growth in the number of health applications (apps), little is known about how well these apps protect their users' health-related data. This gap in knowledge is of particular concern for apps targeting people with dementia, whose cognitive impairment puts them at increased risk of privacy breaches. In this article, we determine how many dementia apps have privacy policies and how well they protect user data. METHODS: Our analysis included all iPhone apps that matched the search terms "medical + dementia" or "health & fitness + dementia" and collected user-generated content...
June 1, 2017: American Journal of Geriatric Psychiatry
keyword
keyword
18556
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"