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https://www.readbyqxmd.com/read/29790832/without-warning-worker-deaths-from-heat-2014-2016
#1
Cora Roelofs
Worker deaths from heat exposure are unlike heat deaths in the general population; workers tend to be outside in variable temperatures and younger than sixty-five years. Climate change will increase the frequency, duration, and variability of hot temperatures. Public health warning systems, such as the Heat Index of the National Weather Service, do not generally account for workers' greater likelihood of exposure to direct sunlight or exertion. Only 28% of the 79 worker heat-related fatalities during 2014-2016 occurred on days when the National Weather Service warning would have included the possibility of fatal heat stroke...
January 1, 2018: New Solutions: a Journal of Environmental and Occupational Health Policy: NS
https://www.readbyqxmd.com/read/29784570/research-gaps-in-wilderness-medicine
#2
Daniel Tritz, Kody Dormire, Travis Brachtenbach, Joshua Gordon, Donald Sanders, David Gearheart, Julia Crawford, Matt Vassar
INTRODUCTION: Wilderness medicine involves the treatment of individuals in remote, austere environments. Given the high potential for injuries as well as the unique treatment modalities required in wilderness medicine, evidence-based clinical practice guidelines are necessary to provide optimal care. In this study, we identify evidence gaps from low-quality recommendations in wilderness medicine clinical practice guidelines and identify new/ongoing research addressing them. METHODS: We included relevant clinical practice guidelines from the Wilderness Medical Society and obtained all 1C or 2C level recommendations...
May 18, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/29775421/probability-of-heat-intolerance-standardized-interpretation-of-heat-tolerance-testing-results-versus-specialist-judgment
#3
Haggai Schermann, Erin Craig, Einat Yanovich, Itay Ketko, Gary Kalmanovich, Ran Yanovich
CONTEXT:   The heat-tolerance test (HTT) is a screening tool for secondary prevention of exertional heat illness by the Israel Defense Forces. To discern participant tolerance, recruits are exposed to intermediate environmental and exercise stresses, and their physiological responses, core temperature, and heart rate are monitored. When their physiological measures rise at a higher rate or exceed the upper levels of absolute values compared with other participants, heat intolerance (HI) is diagnosed...
April 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29775289/mass-spectral-detection-of-diethoxyphospho-tyrosine-adducts-on-proteins-from-hek293-cells-using-monoclonal-antibody-depy-for-enrichment
#4
Seda Onder, Lawrence M Schopfer, Ozden Tacal, Thomas A Blake, Rudolph C Johnson, Oksana Lockridge
Chronic illness from exposure to organophosphorus toxicants is hypothesized to involve modification of unknown proteins. Tyrosine in proteins that have no active site serine readily reacts with organophosphorus toxicants. We developed a monoclonal antibody, depY, that specifically recognizes diethoxyphospho-tyrosine in proteins and peptides, independent of the surrounding amino acid sequence. Our goal in the current study was to identify diethoxyphosphorylated proteins in human HEK293 cell lysate treated with chlorpyrifos oxon...
May 18, 2018: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/29774830/frequent-implication-of-multistress-tolerant-campylobacter-jejuni-in-human-infections
#5
Euna Oh, Linda Chui, Junghee Bae, Vincent Li, Angela Ma, Steven K Mutschall, Eduardo N Taboada, Lynn M McMullen, Byeonghwa Jeon
Campylobacter jejuni, a major cause of bacterial foodborne illnesses, is considered highly susceptible to environmental stresses. In this study, we extensively investigated the stress tolerance of 121 clinical strains of C. jejuni against 5 stress conditions (aerobic stress, disinfectant exposure, freeze-thaw, heat treatment, and osmotic stress) that this pathogenic bacterium might encounter during foodborne transmission to humans. In contrast to our current perception about high stress sensitivity of C. jejuni, a number of clinical strains of C...
June 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29771685/enterotoxigenic-escherichia-coli-blood-group-a-interactions-intensify-diarrheal-severity
#6
Pardeep Kumar, F Matthew Kuhlmann, Subhra Chakroborty, A Louis Bourgeois, Jennifer Foulke-Abel, Brunda Tumala, Tim J Vickers, David A Sack, Barbara DeNearing, Clayton D Harro, W Shea Wright, Jeffrey C Gildersleeve, Matthew A Ciorba, Srikanth Santhanam, Chad K Porter, Ramiro L Gutierrez, Michael G Prouty, Mark S Riddle, Alexander Polino, Alaullah Sheikh, Mark Donowitz, James M Fleckenstein
Enterotoxigenic Escherichia coli (ETEC) infections are highly prevalent in developing countries where clinical presentations range from asymptomatic colonization to severe cholera-like illness. The molecular basis for these varied presentations, that may involve strain-specific virulence features as well as host factors, have not been elucidated. We demonstrate that when challenged with ETEC strain H10407, originally isolated from a case of cholera-like illness, blood group A human volunteers developed severe diarrhea more frequently than individuals from other blood groups...
May 17, 2018: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29757912/dysfunction-of-iron-metabolism-and-iron-regulatory-proteins-in-the-rat-hippocampus-after-heat-stroke
#7
Jing Liu, Shengming Wan, Yun Zhang, Shu Zhang, Hongying Zhang, Shiwen Wu
Heat stroke, the most serious type of heat illness, refers to the presence of hyperthermia (core temperature >40°C), accompanied by central nervous system dysfunction. The hippocampus is a particularly vulnerable region in the early stage of heat stroke. Increasing evidence suggests that dysregulation of brain iron metabolism is involved in many neurodegenerative diseases. However, whether heat stroke causes dysfunction of iron metabolism, as well as iron-regulatory proteins, in the hippocampus remains unknown...
May 11, 2018: Shock
https://www.readbyqxmd.com/read/29755105/current-and-potential-future-seasonal-trends-of-indoor-dwelling-temperature-and-likely-health-risks-in-rural-southern-africa
#8
Thandi Kapwata, Michael T Gebreslasie, Angela Mathee, Caradee Yael Wright
Climate change has resulted in rising temperature trends which have been associated with changes in temperature extremes globally. Attendees of Conference of the Parties (COP) 21 agreed to strive to limit the rise in global average temperatures to below 2 °C compared to industrial conditions, the target being 1.5 °C. However, current research suggests that the African region will be subjected to more intense heat extremes over a shorter time period, with projections predicting increases of 4⁻6 °C for the period 2071⁻2100, in annual average maximum temperatures for southern Africa...
May 10, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29755052/lessons-learned-from-data-collection-as-health-screening-in-underserved-farmworker-communities
#9
Joan Flocks, J Antonio Tovar, Eugenia Economos, Valerie Vi Thien Mac, Abby Mutic, Katherine Peterman, Linda McCauley
BACKGROUND: Girasoles is an academic-community partnership investigating heat-related illness (HRI) among farm-workers. An unexpected outcome is health screening and intervention for participants without access to health care. OBJECTIVES: We present a case of renal failure in a farmworker, detected during data collection, to illustrate how academic-community collaboration can result in clinical benefits for study participants. METHODS: Girasoles is examining physiologic responses to heat stress, associated vulnerability factors, and HRI symptoms...
2018: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/29754749/comparison-of-oral-and-axillary-temperatures-in-intubated-pediatric-patients
#10
Danielle Wood, Mary Heitschmidt, Louis Fogg
PURPOSE: Accurate body temperature measurement is essential in providing timely care to critically ill patients. Current practice within the Pediatric ICU (PICU) at a Midwestern academic medical center is to obtain axillary temperatures in endotracheally intubated patients. According to research, axillary temperatures have greater variance than other forms of temperature measurement. Research in adult patients show that oral temperature measurement in endotracheally intubated patients is acceptable as the heated gases from the ventilator has no significant effect on measured temperatures...
May 10, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29742138/a-novel-early-risk-assessment-tool-for-detecting-clinical-outcomes-in-patients-with-heat-related-illness-j-erato-score-development-and-validation-in-independent-cohorts-in-japan
#11
Kei Hayashida, Yutaka Kondo, Toru Hifumi, Junya Shimazaki, Yasutaka Oda, Shinichiro Shiraishi, Tatsuma Fukuda, Junichi Sasaki, Keiki Shimizu
BACKGROUND: We sought to develop a novel risk assessment tool to predict the clinical outcomes after heat-related illness. METHODS: Prospective, multicenter observational study. Patients who transferred to emergency hospitals in Japan with heat-related illness were registered. The sample was divided into two parts: 60% to construct the score and 40% to validate it. A binary logistic regression model was used to predict hospital admission as a primary outcome. The resulting model was transformed into a scoring system...
2018: PloS One
https://www.readbyqxmd.com/read/29726698/on-the-use-of-wearable-physiological-monitors-to-assess-heat-strain-during-occupational-heat-stress
#12
Sean R Notley, Andreas D Flouris, Glen P Kenny
Workers in many industries are required to perform arduous work in high heat stress conditions, which can lead to rapid increases in body temperature that elevate the risk of heat-related illness or even death. Traditionally, effort to mitigate work-related heat injury has been directed to the assessment of environmental heat stress (e.g., wet-bulb globe temperature), rather than the associated physiological strain responses (e.g., heart rate, skin and core temperatures). However, since a workers physiological response to a given heat stress is modified independently by inter-individual factors (e...
May 4, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29715717/antiviral-and-anti-inflammatory-activities-of-pochonin-d-a-heat-shock-protein-90-inhibitor-against-rhinovirus-infection
#13
Jae-Hyoung Song, Aeri Shim, Yeon-Jeong Kim, Jae-Hee Ahn, Bo-Eun Kwon, Thuy Trang Pham, Jongkook Lee, Sun-Young Chang, Hyun-Jeong Ko
Human rhinoviruses (HRV) are one of the major causes of common cold in humans and are also associated with acute asthma and bronchial illness. Heat-shock protein 90 (Hsp90), a molecular chaperone, is an important host factor for the replication of single-strand RNA viruses. In the current study, we examined the effect of the Hsp90 inhibitor pochonin D, in vitro and in vivo , using a murine model of human rhinovirus type 1B (HRV1B) infection. Our data suggested that Hsp90 inhibition significantly reduced the inflammatory cytokine production and lung damage caused by HRV1B infection...
May 2, 2018: Biomolecules & Therapeutics
https://www.readbyqxmd.com/read/29696983/update-heat-illness-active-component-u-s-armed-forces-2017
#14
(no author information available yet)
No abstract text is available yet for this article.
April 2018: MSMR
https://www.readbyqxmd.com/read/29682002/household-air-pollution-hap-microenvironment-and-child-health-strategies-for-mitigating-hap-exposure-in-urban-rwanda
#15
Ipsita Das, Joseph Pedit, Sudhanshu Handa, Pamela Jagger
Exposure to household air pollution (HAP) from cooking and heating with solid fuels is major risk factor for morbidity and mortality in sub-Saharan Africa. Children under five are particularly at risk for acute lower respiratory infection. We use baseline data from randomized controlled trial evaluating a household energy intervention in Gisenyi, Rwanda to investigate the role of the microenvironment as a determinant of children's HAP-related health symptoms. Our sample includes 529 households, with 694 children under five...
2018: Environmental Research Letters: ERL [Web Site]
https://www.readbyqxmd.com/read/29678913/long-term-survival-and-thermal-death-kinetics-of-enterohemorrhagic-escherichia-coli-serogroups-o26-o103-o111-and-o157-in-wheat-flour
#16
Fereidoun Forghani, Meghan den Bakker, Alexandra N Futral, Francisco Diez-Gonzalez
Wheat flour has been associated with outbreaks of enterohemorrhagic Escherichia coli (EHEC), but little is known on EHEC's survival during storage and thermal processing. The objectives of this study were to determine long-term viability and thermal inactivation kinetics of serogroups O26, O103, O111 and O157. Wheat flour samples were inoculated with a cocktail of five strains of a single serogroup and stored at 23 and 35 °C. Inoculated samples were heated at 55, 60, 65 and 70 °C. Viability was determined by plate counting...
April 20, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29669616/comparison-of-thermal-manikin-modeling-and-human-subjects-response-during-use-of-cooling-devices-under-personal-protective-ensembles-in-the-heat
#17
Tyler Quinn, Jung-Hyun Kim, Yongsuk Seo, Aitor Coca
IntroductionPersonal protective equipment (PPE) recommended for use in West Africa during the Ebola outbreak increased risk for heat illness, and countermeasures addressing this issue would be valuable.Hypothesis/ProblemThe purpose of this study was to examine the physiological impact and heat perception of four different personal cooling devices (PCDs) under impermeable PPE during low-intensity exercise in a hot and humid environment using thermal manikin modeling and human testing. METHODS: Six healthy male subjects walked on a treadmill in a hot/humid environment (32°C/92% relative humidity [RH]) at three metabolic equivalents (METs) for 60 minutes wearing PPE recommended for use in West Africa and one of four different personal cooling devices (PCDs; PCD1, PCD2, PCD3, and PCD4) or no PCD for control (CON)...
April 19, 2018: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29662887/characteristics-of-heat-illness-during-hajj-a-cross-sectional-study
#18
Doaa A Abdelmoety, Nahid K El-Bakri, Wedian O Almowalld, Zyad A Turkistani, Bassam H Bugis, Eshraq A Baseif, Mohamed H Melbari, Khaled AlHarbi, Amani Abu-Shaheen
Introduction: Data regarding the characteristics and outcomes of heat illness are lacking in the literature. The present study aimed to identify the clinical characteristics, morbidity, management, and mortality associated with heat illness among Hajj participants. Methods: A cross-sectional study was conducted during the Hajj in 2016 on patients who presented to emergency departments and were diagnosed with heat exhaustion or heatstroke. Data were collected using a structured collection sheet developed based on the literature...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29621422/fire-service-instructors-working-practices-a-uk-survey
#19
Emily R Watkins, Mark Hayes, Peter Watt, Alan J Richardson
Analysis of Fire Service Instructors (FSI) working practices and health is needed to minimise health risks related to heat illness, cardiovascular events and immunological stress. Online surveys were distributed to UK FSI and Firefighters (FF). One hundred and thirty FSI (age: 43±7yrs) and 232 FF (age: 41±8yrs) responded. FSI experienced 2-10 live fires per week, with 45% of FSI reporting management does not set a limit on the number of exposures. Few FSI followed hydration guidelines, or cooling methods...
April 5, 2018: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/29620470/study-of-an-outbreak-of-highly-pathogenic-avian-influenza-h5n8-in-commercial-pekin-ducks-anas-platyrhynchos-domesticus-in-california
#20
Simone Stoute, Beate Crossley, H L Shivaprasad
A February 2015 outbreak of highly pathogenic avian influenza (HPAI) H5N8 in a flock of commercial Pekin ducks ( Anas platyrhynchos domesticus) in California was investigated in detail. Approximately 17,349 five-wk-old ducks experienced an increased mortality from a normal of eight birds per day to 24, 18, 24, 33, and 61 birds per day, respectively, in the last 5 days prior to flock depopulation. Clinically, there was decreased water and feed consumption, and approximately 1.0% of the affected flock exhibited neurologic signs...
March 2018: Avian Diseases
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