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https://www.readbyqxmd.com/read/28800265/use-of-snomed-ct%C3%A2-and-loinc%C3%A2-to-standardize-terminology-for-primary-care-asthma-electronic-health-records
#1
M Diane Lougheed, Nicola J Thomas, Nastasia V Wasilewski, Alison H Morra, Janice P Minard
OBJECTIVES: The burden of asthma ranks among the highest for chronic diseases. Interoperable EHRs can improve the management of chronic diseases such as asthma by facilitating sharing of data between health care settings along the continuum of care. Terminology such as SNOMED CT® (Systematized Nomenclature of Medicine-Clinical Terms) and LOINC® (Logistical Observation Identifier Names and Codes) are prerequisites for interoperability of electronic health records (EHRs). We sought to determine the extent to which data elements in a validated asthma care map (ACM) are congruent with these terminologies...
August 11, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28797558/prevalence-and-predictors-associated-with-severe-pulmonary-hypertension-in-copd
#2
Mitra Samareh Fekri, Mehdi Torabi, Sara Azizi Shoul, Moghaddameh Mirzaee
BACKGROUND: Pulmonary hypertension (PH) is one of the most common complications of COPD (chronic obstructive pulmonary disease), but its severe form is uncommon. Various factors play an important role in the occurrence and severity of pulmonary hypertension in patients. METHODS: This cross-sectional study was performed on patients with COPD referred to an emergency department over a one-year period. The tests-including complete blood count (CBC) and arterial blood gas (ABG), pulmonary functional test (PFT) and echocardiography-were performed for all patients to measure mPAP (mean pulmonary artery pressure), ejection fraction (EF) and body mass index (BMI)...
August 5, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28773845/low-threshold-and-high-intensity-random-lasing-enhanced-by-mncl%C3%A2
#3
Zhenzhen Shang, Mingchao Yang, Luogen Deng
Energy transfer is known to have a significant influence on random lasers. However, the study about the effect of energy transfer between metallic salt and dye molecules on random lasers is still lacking at present. Here, we investigate random lasing actions in Pyrromethene-597 (PM597), PM597-doped MnCl₂ (manganese (II) chloride), PM597-doped polymer-dispersed liquid crystal (PDLC) and PM597-doped PDLC with MnCl₂ capillary systems. We find that random lasing of the systems with MnCl₂ exhibits lower threshold, higher intensity, sharper peak and variable resonance wavelength in comparison with the systems without MnCl₂...
August 24, 2016: Materials
https://www.readbyqxmd.com/read/28772006/accuracy-of-magnetic-resonance-imaging-for-grading-of-subglottic-stenosis-in-patients-with-granulomatosis-with-polyangiitis-correlation-with-pulmonary-function-tests-and-laryngoscopy
#4
Frank O Henes, Martin Laudien, Laura Linsenhoff, Jan P Bremer, Tim Oqueka, Gerhard Adam, Gerhard Schön, Peter Bannas
OBJECTIVES: To compare magnetic resonance imaging (MRI)-based and laryngoscopy-based subglottic stenosis (SGS) grading with pulmonary function tests (PFT) in patients with granulomatosis with polyangiitis (GPA). METHODS: In this retrospective study we included 118 examinations of 44 patients with GPA and suspected SGS. All patients underwent MRI, laryngoscopy, and PFT. Stenosis was graded on a 4-point scale by endoscopy and MRI using the Meyer-Cotton (MC)-Score (score1: ≤50%; 2: 51-70%; 3: 71-99%; 4: 100%) and as percentage by MRI...
August 3, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28761337/size-variation-and-collapse-of-emphysema-holes-at-inspiration-and-expiration-ct-scan-evaluation-with-modified-length-scale-method-and-image-co-registration
#5
Sang Young Oh, Minho Lee, Joon Beom Seo, Namkug Kim, Sang Min Lee, Jae Seung Lee, Yeon Mok Oh
A novel approach of size-based emphysema clustering has been developed, and the size variation and collapse of holes in emphysema clusters are evaluated at inspiratory and expiratory computed tomography (CT). Thirty patients were visually evaluated for the size-based emphysema clustering technique and a total of 72 patients were evaluated for analyzing collapse of the emphysema hole in this study. A new approach for the size differentiation of emphysema holes was developed using the length scale, Gaussian low-pass filtering, and iteration approach...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28758573/shrinking-lung-syndrome-in-systemic-lupus-erythematosus-a-single-centre-experience
#6
M Deeb, K Tselios, D D Gladman, J Su, M B Urowitz
Introduction Shrinking lung syndrome (SLS) is a rare manifestation of systemic lupus erythematosus (SLE), characterized by decreased lung volumes and extra-pulmonary restriction. The aim of this study was to describe the characteristics of SLS in our lupus cohort with emphasis on prevalence, presentation, treatment and outcomes. Patients and methods Patients attending the Toronto Lupus Clinic since 1980 ( n = 1439) and who had pulmonary function tests (PFTs) performed during follow-up were enrolled ( n = 278)...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28750541/influence-of-different-cleaning-processes-on-the-surface-chemistry-of-gold-nanoparticles
#7
Rita La Spina, Valentina Spampinato, Douglas Gilliland, Isaac Ojea-Jimenez, Giacomo Ceccone
In this paper, the authors have investigated the effects of different cleaning methods (centrifugation and dialysis) on the surface chemistry and composition of 15 nm sodium citrate stabilized gold nanoparticles. The nuclear magnetic resonance (NMR) results indicate that three centrifugation cycles are sufficient to remove most of the citrate molecules, while centrifuged liquid sedimentation and dynamic light scattering data reveal some degree of nanoparticle aggregation when three centrifugation cycles are exceeded...
July 27, 2017: Biointerphases
https://www.readbyqxmd.com/read/28748803/serial-mri-scan-of-posterior-fossa-tumours-predict-patients-at-risk-of-developing-neurocognitive-impairment
#8
Ramadhan Othman, Kurdistan Gh Abdullah
Background: Brain tumours are the most common solid tumours in children. More than 50% of these tumours develop in the posterior cranial fossa. Long term survivors of posterior fossa tumours (PFT) suffer from neurocognitive and memory issues. We hypothesized that serial MRI scanning of brain would show differences in hippocampal and ACC volume change in PFT patients treated with and without chemo-radiotherapy. Material and Methods: Twelve patients (8 females and 4 males) underwent 76 serial MR imaging examinations before and during treatment for posterior fossa tumours...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28748260/clinical-predictors-for-reactive-tube-feeding-in-patients-with-advanced-oropharynx-cancer-receiving-radiotherapy%C3%A2-%C3%A2-%C3%A2-chemotherapy
#9
Belinda Vangelov, Robert I Smee
Enteral feeding is often required for nutrition support in head and neck cancer patients when oral intake is inadequate. When to initiate the insertion of a feeding tube continues to be a debated issue in our institution. We investigated the use of reactive feeding tubes (RFTs) in patients with advanced stage oropharynx cancer (OPC). Data were retrospectively collected on 131 patients who had radiotherapy (RT) ± chemotherapy from 2005 to 2015. Predictors for RFT insertion were investigated. Weight loss during RT was compared between those with RFT versus prophylactic tubes (PFTs) versus no tube, and survival outcomes evaluated...
July 26, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28742806/long-term-follow-up-of-pulmonary-function-in-fabry-disease-a-bi-center-observational-study
#10
Daniel P Franzen, Albina Nowak, Sarah R Haile, Dominique Mottet, Marco Bonani, Olivier Dormond, Malcolm Kohler, Pierre A Krayenbuehl, Frederic Barbey
INTRODUCTION: Fabry disease (FD) is a lysosomal storage disorder leading to decreased α-galactosidase A enzyme activity and subsequent abnormal accumulation of glycosphingolipids in various organs. Although histological evidence of lung involvement has been demonstrated, the functional impact of these changes is less clear. MATERIALS AND METHODS: Adult patients with FD who had yearly pulmonary function tests (PFT) at two centers from 1999 thru 2015 were eligible for this observational study...
2017: PloS One
https://www.readbyqxmd.com/read/28741147/constipation-in-degenerative-cervico-thoracic-spine-myelopathy-a-simple-co-existence-or-a-complex-inter-relationship
#11
Anant Mehrotra, Janmejay Jamdar, Pradeep Sharma, Chaitanya Godbole, Suyash Singh, Kuntal Kanti Das, Abhai Verma, Kamlesh Singh Bhaisora, Jayesh Sardhara, Awadhesh Kumar Jaiswal, Rabi Narayan Sahu, Arun Kumar Srivastava, Sanjay Behari, Raj Kumar
PURPOSE: Identify factors affecting constipation and post surgical improvement in patients of myelopathy. METHODS: Sixty-four patients with myelopathy due to extradural spine pathologies (47 cervical; 17 thoracic spine, male:female-5.4:1 with mean age 46.16) underwent evaluation including Bristol stool scale (BSS), PFT and uroflowmetry. All cases were evaluated by gastroenterologist to rule out any intrinsic bowel disease. Chi-square test, Kruskal-Wallis/Mann-Whitney U test and Wilcoxon signed rank test were employed to ascertain statistical significance...
July 24, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28738344/quantitative-low-dose-computed-tomography-of-the-lung-parenchyma-and-airways-for-the-differentiation-between-chronic-obstructive-pulmonary-disease-and-asthma-patients
#12
Huai Chen, Qing-Si Zeng, Min Zhang, Rong-Chang Chen, Ting-Ting Xia, Wei Wang, Xiaoyin Xu, Yubao Guan
BACKGROUND: It is difficult to differentiate between chronic obstructive pulmonary disease (COPD) and asthma in clinics; therefore, for diagnostic purposes, imaging-based measurements could be beneficial to differentiate between the two diseases. OBJECTIVES: We aim to analyze quantitative measurements of the lung and bronchial parameters that are provided by low-dose computed tomography (CT) to differentiate COPD and asthma from an imaging perspective. MATERIALS AND METHODS: 69 COPD patients, 52 asthma patients, and 20 healthy subjects were recruited to participate in CT imaging and pulmonary function tests (PFTs)...
July 25, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28732823/correlation-of-pulmonary-function-and-usual-interstitial-pneumonia-computed-tomography-patterns-in-idiopathic-pulmonary-fibrosis
#13
Antonella Arcadu, Suzanne C Byrne, Pietro Pirina, Thomas E Hartman, Brian J Bartholmai, Teng Moua
BACKGROUND: Little is known about presenting 'inconsistent' or 'possible' usual interstitial pneumonia (UIP) computed tomography (CT) patterns advancing to 'consistent' UIP as disease progresses in idiopathic pulmonary fibrosis (IPF). We hypothesized that if 'consistent' UIP represented more advanced disease, such a pattern on presentation should also correlate with more severe pulmonary function test (PFT) abnormalities. MATERIAL AND METHODS: Consecutive IPF patients (2005-2013) diagnosed by international criteria with baseline PFT and CT were included...
August 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28728932/the-complex-restrictive-pulmonary-function-pattern-clinical-and-radiologic-analysis-of-a-common-but-previously-undescribed-restrictive-pattern
#14
Ryan D Clay, Vivek N Iyer, Dereddi Raja Reddy, Brittany Siontis, Paul D Scanlon
BACKGROUND: Most patients with restriction have a pulmonary function test (PFT) pattern in which total lung capacity (TLC), FVC, and FEV1 are reduced to a similar degree. This pattern is called "simple restriction" (SR). In contrast, we commonly observe a pattern in which FVC percent predicted (pp) is disproportionately reduced relative to TLCpp. This pattern is termed "complex restriction" (CR), and we attempted to characterize its clinical, radiologic, and physiologic features. METHODS: This study reviewed PFT results of patients tested between November 2009 and June 2013 who had restriction (TLC less than the lower limit of normal)...
July 17, 2017: Chest
https://www.readbyqxmd.com/read/28728441/ability-of-pulmonary-function-decline-to-predict-death-in-amyotrophic-lateral-sclerosis-patients
#15
Irina Enache, Cristina Pistea, Marie Fleury, Mickael Schaeffer, Monique Oswald-Mammosser, Andoni Echaniz-Laguna, Christine Tranchant, Nicolas Meyer, Anne Charloux
OBJECTIVES: Objectives were to evaluate the relative risk of death associated with lung function decline in patients with amyotrophic lateral sclerosis (ALS), and to examine the ability of ALS patients to perform volitional pulmonary function tests (PFTs). METHODS: The PFTs of 256 consecutive patients referred to the Strasbourg University Hospital ALS Centre over an eight-year period were reviewed. Slow vital capacity (VC), maximal inspiratory and expiratory pressures (MIP, MEP), sniff nasal inspiratory pressure (SNIP), and peak cough flow (PCF) were performed at diagnosis and then every four months...
July 20, 2017: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/28725123/polymicrobial-pyogenic-flexor-tenosynovitis-of-the-index-finger-and-first-ray-resulting-from-autophagia
#16
Andrew P Harris, Joey Johnson, Augusta Kluk, Neill Y Li, Avi D Goodman, Edward Akelman
Pyogenic flexor tenosynovitis (PFT) is a well known infectious condition of the hand, involving the inoculation of the flexor tendon sheath with microorganisms. Many cases have been reported, common causes including direct inoculation by a puncture wound and deep lacerations extending into the flexor tendon sheath. In this report, we present a case of a 50 year old female with PFT resulting from autophagia (consuming one's own body parts, in our case, fingers) successfully treated with irrigation and debridement, amputation of the index finger at the metacarpophalangeal joint and antibiotic therapy...
September 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28720000/differentiation-between-pyogenic-flexor-tenosynovitis-and-other-finger-infections
#17
Colin D Kennedy, Alexander S Lauder, Jonathan R Pribaz, Stephen A Kennedy
BACKGROUND: Hospital transfer decisions regarding pyogenic flexor tenosynovitis (PFT) are made difficult by emergency department presentations similar to other finger infections, with pain, redness, and functional limitation. Our objectives were to: (1) determine diagnostic sensitivity and specificity of Kanavel signs; and (2) identify existing factors most predictive of PFT during initial presentation. METHODS: Adult patients who underwent surgical consultation for concern of PFT over a 5-year period were identified retrospectively...
February 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28707988/first-clinical-report-of-helical-tomotherapy-with-simultaneous-integrated-boost-for-synchronous-bilateral-breast-cancer
#18
Tabassum Wadasadawala, Shanu Jain, Siji Paul, Reena Phurailatpam, Kishore Joshi, Palak Popat, Sandip Tandon, Aruna Alahari, Rajiv Sarin
OBJECTIVE: Radiotherapy for synchronous bilateral breast cancer (SBBC) is technically very challenging. This study reports the clinical feasibility, dosimetry and safety of helical tomotherapy (HT) with simultaneous integrated boost (SIB) in patients treated with adjuvant radiotherapy for SBBC. MATERIAL AND METHODS: Twenty one women with SBBC treated with HT from January 2013 to June 2016 were retrospectively evaluated. Radiation lung toxicity was assessed using pulmonary function test (PFT) and high resolution computerized tomography scan (HRCT) scan at baseline and 1 year post RT in 18 patients...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28692550/long-term-pulmonary-outcomes-in-pediatric-survivors-of-high-risk-neuroblastoma
#19
Anne Stone, Danielle Novetsky Friedman, Stefan Worgall, Brian H Kushner, Suzanne Wolden, Shakeel Modak, Michael P LaQuaglia, Xian Wu, Nai-Kong Cheung, Charles A Sklar
BACKGROUND: Children with high-risk neuroblastoma are exposed to multimodality therapies early in life and survivors confront late therapy-related toxicities. This study assessed respiratory symptoms, pulmonary function tests (PFTs), and risk factors for abnormalities among survivors. MATERIALS AND METHODS: High-risk neuroblastoma survivors followed in the long-term follow-up clinic at Memorial Sloan Kettering Cancer Center were enrolled. Self-administered symptom questionnaires were completed...
July 7, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28691888/extracellular-signal-regulated-protein-kinases-protein-kinase-b-p53-bh3-interacting-domain-death-agonist-pathway-regulates-gingipain-induced-apoptosis-in-osteoblasts
#20
Fuping Zhang, Qihong Qiu, Xiangchen Song, Yuting Chen, Juan Wu, Min Liang
BACKGROUND: Gingipains are cysteine proteases produced by Porphyromonas gingivalis, the predominant pathogen in chronic periodontitis. The present study aimed to examine the role of gingipains in promoting apoptosis in osteoblasts. METHODS: Human calvarial osteoblasts and osteoblast MC3T3-E1 cells were treated with 8.348 U/L gingipains. Flow cytometry analysis and terminal deoxynucleotidyl transferase (TdT)-mediated deoxy-UTP nick end labeling (TUNEL) staining were used to detect cell apoptosis...
July 10, 2017: Journal of Periodontology
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