keyword
MENU ▼
Read by QxMD icon Read
search

Nice clinical guidelines

keyword
https://www.readbyqxmd.com/read/29453511/developing-new-age-specific-prostate-specific-antigen-thresholds-for-testing-for-prostate-cancer
#1
Rebecca Gilbert, Kate Tilling, Richard M Martin, J Athene Lane, Michael Davis, Freddie C Hamdy, David E Neal, Jenny L Donovan, Chris Metcalfe
PURPOSE: To examine whether age-related reference ranges for "normal" prostate-specific antigen (PSA) change (determined in men without prostate cancer) can be used to identify men at high risk of having prostate cancer. METHODS: Subjects were men aged 50-69 years with PSA < 10 ng/mL from the UK-based Prostate Testing for cancer and Treatment (ProtecT) study. Men with prostate cancer were categorized as high or low risk of progression (Low risk: Gleason score ≤ 6 and stage T1-T2a; High risk: Gleason score 7-10 or stage T2C)...
February 16, 2018: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29451407/advancements-in-drug-development-for-diarrhea-predominant-irritable-bowel-syndrome
#2
Giovanni Dothel, Maria Raffaell Barbaro, Emanuel Raschi, Giovanni Barbara, Fabrizio De Ponti
Introduction Diarrhea-predominant irritable bowel syndrome (IBS-D) is a common disorder characterized by a complex pathophysiology hampering optimal targeted drug development. Recent advances in our understanding of key underlying mechanisms prompted novel therapeutics including novel pharmacological approaches. Areas covered This review summarizes the latest advancements in the pipeline of IBS-D drugs focusing on new pharmacological targets, efficacy and safety of medicinal products considering the recent harmonization of regulatory requirements by the FDA and the EMA...
February 16, 2018: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/29448987/the-refeeding-syndrome-importance-of-phosphorus
#3
REVIEW
Marta Araujo Castro, Clotilde Vázquez Martínez
Refeeding syndrome (RS) is a complex disease that occurs when nutritional support is initiated after a period of starvation. The hallmark feature is the hypophosphataemia, however other biochemical abnormalities like hypokalaemia, hypomagnesaemia, thiamine deficiency and disorder of sodium and fluid balance are common. The incidence of RS is unknown as no universally accepted definition exists, but it is frequently underdiagnosed. RS is a potentially fatal, but preventable, disorder. The identification of patients at risk is crucial to improve their management...
February 12, 2018: Medicina Clínica
https://www.readbyqxmd.com/read/29406177/could-patient-controlled-thirst-driven-fluid-administration-lead-to-more-rapid-rehydration-than-clinician-directed-fluid-management-an-early-feasibility-study
#4
F Hughes, S C Ng, M Mythen, H Montgomery
BACKGROUND: Fluid management is a major factor determining perioperative outcome, yet in reality, fluid administration practice is variable. Thirst however, is a highly sensitive and reliable indicator of fluid deficits. We explored the use of thirst sensation to trigger i.v. fluid boluses to guide individualized fluid management. METHODS: We performed a randomised double crossover trial on 16 healthy male volunteers, of mean age 31 yr and BMI 24.4 kg m-2. Twice, after administrations of oral furosemide (40 mg) and 12 h of oral fluid restriction, participants received a 4-h i...
February 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29402332/the-efficacy-and-mechanism-evaluation-of-treating-idiopathic-pulmonary-fibrosis-with-the-addition-of-co-trimoxazole-eme-tipac-study-protocol-for-a-randomised-controlled-trial
#5
Matthew Hammond, Allan B Clark, Anthony P Cahn, Edwin R Chilvers, William Duncan Fraser, David M Livermore, Toby M Maher, Helen Parfrey, Ann Marie Swart, Susan Stirling, David Thickett, Moira Whyte, Andrew Wilson
BACKGROUND: We hypothesise, based upon the findings from our previous trial, that the addition of co-trimoxazole to standard therapy is beneficial to patients with moderate to severe idiopathic pulmonary fibrosis (IPF). We aim to investigate this by assessing unplanned hospitalisation-free survival (defined as time from randomisation to first non-elective hospitalisation, lung transplant or death) and to determine whether any effect relates to changes in infection and/or markers of disease control and neutrophil activity...
February 5, 2018: Trials
https://www.readbyqxmd.com/read/29394453/exercise-based-cardiac-rehabilitation-for-adults-with-stable-angina
#6
REVIEW
Linda Long, Lindsey Anderson, Alice M Dewhirst, Jingzhou He, Charlene Bridges, Manish Gandhi, Rod S Taylor
BACKGROUND: A previous Cochrane review has shown that exercise-based cardiac rehabilitation (CR) can benefit myocardial infarction and post-revascularisation patients. However, the impact on stable angina remains unclear and guidance is inconsistent. Whilst recommended in the guidelines of American College of Cardiology/American Heart Association and the European Society of Cardiology, in the UK the National Institute for Health and Care Excellence (NICE) states that there is "no evidence to suggest that CR is clinically or cost-effective for managing stable angina"...
February 2, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29393997/a-multicentre-integration-of-a-computer-led-follow-up-in-surgical-oncology-is-valid-and-safe
#7
Hesham Salem, Giacomo Caddeo, Jon McFarlane, Kunjan Patel, Lynda Cochrane, Daniele Soria, Mike Henley, Jonathan Lund
BACKGROUND: Prostate cancer (CaP) has a rising number of patients requiring routine follow up. In this study, we aimed to test a computer led follow up service for prostate cancer in two UK hospitals. The testing aimed to validate the computer Expert system in making clinical decisions according to the individual patient's clinical need. The valid model should accurately identify patients with disease recurrence or treatment failure based on their blood test and clinical picture. METHODS: A clinical decision support system (CDSS) was developed from European (EAU) and national (NICE) guidelines along with knowledge acquired from Urologists...
February 2, 2018: BJU International
https://www.readbyqxmd.com/read/29365071/trends-in-prescribing-of-non-steroidal-anti-inflammatory-drugs-in-patients-with-cardiovascular-disease-influence-of-national-guidelines-in-uk-primary-care
#8
Ying Chen, John Bedson, Richard A Hayward, Kelvin P Jordan
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat pain, but have potential side effects in patients with cardiovascular disease (CVD). Objectives: To determine trends in NSAIDs prescribing between 2002 and 2010 in patients with CVD, and ascertain whether prescribing patterns changed following publication of major national (the Medicines and Healthcare products Regulatory Agency (MHRA) and the National Institute for Health and Clinical Excellence (NICE)) guidance to GPs...
January 22, 2018: Family Practice
https://www.readbyqxmd.com/read/29344408/differential-research-impact-in-cancer-practice-guidelines-evidence-base-lessons-from-esmo-nice-and-sign
#9
Elena Pallari, Anthony W Fox, Grant Lewison
Background: This is an appraisal of the impact of cited research evidence underpinning the development of cancer clinical practice guidelines (CPGs) by the professional bodies of the European Society for Medical Oncology (ESMO), the National Institute for Health and Care Excellence (NICE) and the Scottish Intercollegiate Guidelines Network (SIGN). Methods: A total of 101 CPGs were identified from ESMO, NICE and SIGN websites across 13 cancer sites. Their 9486 cited references were downloaded from the Web of Science Clarivate Group database, analysed on Excel (2016) using Visual Basic Application macros and imported onto SPSS (V...
2018: ESMO Open
https://www.readbyqxmd.com/read/29335492/assessing-the-effectiveness-of-nice-criteria-for-stratifying-breast-cancer-risk-in-a-uk-cohort
#10
Lucy A Littlejohn, Jim Gibbs, Lee B Jordan, Zosia H Miedzybrodzka, Christine Bell, David Goudie, Jacqueline Dunlop, Jonathan N Berg
Breast cancer risk is a common indication for referral to clinical genetics services. UK National Institute of Health and Care Excellence (NICE) guidelines use family history (FH) to stratify by 10-year risk of breast cancer from age 40. Patients are stratified into population risk (PR, 10-year risk <3%), moderate (MR, 3-8%) and high risk (HR, >8%). Women at increased risk are offered screening at or prior to age 40. To assess the clinical effectiveness of current risk stratification, FH data were obtained for all unaffected women with a FH of breast cancer aged <50, referred to cancer genetics from 2000-2010...
January 15, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29332319/treatment-of-latent-tuberculosis-infection-and-its-clinical-efficacy
#11
REVIEW
Hyung Woo Kim, Ju Sang Kim
The role of the treatment for latent tuberculosis infection (LTBI) has been underscored in the intermediate tuberculosis (TB) burden countries like South Korea. LTBI treatment is recommended only for patients at risk for progression to active TB-those with frequent exposure to active TB cases, and those with clinical risk factors (e.g., immunocompromised patients). Recently revised National Institute for Health and Care Excellence (NICE) guideline recommended that close contacts of individuals with active pulmonary or laryngeal TB, aged between 18 and 65 years, should undergo LTBI treatment...
January 2018: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29331010/implants-for-extracapsular-neck-of-femur-fracture-dynamic-hip-screw-versus-intramedullary-nailing
#12
Faisal Farooq Butt, Adnan Shabbair Hussain, Ahmed Mushtaq Khan, Maria Sultan
Neck of femur fractures are the most prevalent type of injury in elderly trauma patients. Both intra and extra capsular type of fractures are equally distributed in the given population. Traditionally, Extra capsular fractures are fixed with Dynamic Hip screw or Intra medullary nailing based on the type of fracture. NICE (National Institute of Clinical Excellence) recommends fixing 31-A1 and 31-A2 fractures with DHS (Dynamic Hip Screw) whereas AO recommends fixing 31-A1 with DHS and 31-A2.1 subtype with DHS and 31-A2...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29326858/improving-management-of-paediatric-buckle-fracture-in-orthopaedic-outpatients-a-completed-audit-loop
#13
M N Baig, C Egan
Introduction Paediatric patient bone fractures are the source of a large number of orthopaedic outpatient visits, especially for fracture clinics. The National Institute for Health and Care Excellence (NICE) guideline NG38 provides guidance on assessing and managing non-complex fractures, such as buckle (i.e., torus) fractures in paediatric patients. Objective We retrospectively audited outpatient records of children younger than 12 years presenting with distal radius buckle fractures for May and June 2017...
November 8, 2017: Curēus
https://www.readbyqxmd.com/read/29315354/implications-of-guidelines-for-osteoporosis-and-its-treatment
#14
Stephen Tuck, Elizabeth A Little, Terry J Aspray
The development of clinical guidelines is now a more uniform process, with formalised methods to ensure that recommendations are based on current best available evidence from randomised controlled trials and systematic reviews. Over the past 20 years we have seen a growth in guidelines including those relating to osteoporosis, with recommendations varying between and within countries. Some guidelines are concerned with case finding and primary or secondary prevention, such as those produced by the National Institute for Health and Care Excellence (NICE CG146, TA-160, -161, -464), while others focus on specific conditions or risk factors associated with osteoporosis, such as the menopause, coeliac disease and eating disorder...
January 5, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29310599/birthplace-choices-what-are-the-information-needs-of-women-when-choosing-where-to-give-birth-in-england-a-qualitative-study-using-online-and-face-to-face-focus-groups
#15
Lisa Hinton, Carol Dumelow, Rachel Rowe, Jennifer Hollowell
BACKGROUND: Current clinical guidelines and national policy in England support offering 'low risk' women a choice of birth setting. Options include: home, free-standing midwifery unit (FMU), alongside midwifery unit (AMU) or obstetric unit (OU). This study, which is part of a broader project designed to inform policy on 'choice' in relation to childbirth, aimed to provide evidence on UK women's experiences of choice and decision-making in the period since the publication of the Birthplace findings (2011) and new NICE guidelines (2014)...
January 8, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29284456/blood-pressure-self-monitoring-in-pregnancy-examining-feasibility-in-a-prospective-cohort-study
#16
Katherine L Tucker, Kathryn S Taylor, Carole Crawford, James A Hodgkinson, Clare Bankhead, Tricia Carver, Elizabeth Ewers, Margaret Glogowska, Sheila M Greenfield, Lucy Ingram, Lisa Hinton, Khalid S Khan, Louise Locock, Lucy Mackillop, Christine McCourt, Alexander M Pirie, Richard Stevens, Richard J McManus
BACKGROUND: Raised blood pressure (BP) affects approximately 10% of pregnancies worldwide, and a high proportion of affected women develop pre-eclampsia. This study aimed to evaluate the feasibility of self-monitoring of BP in pregnancy in women at higher risk of pre-eclampsia. METHODS: This prospective cohort study of self-monitoring BP in pregnancy was carried out in two hospital trusts in Birmingham and Oxford and thirteen primary care practices in Oxfordshire...
December 28, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29283293/resource-planning-in-glaucoma-a-tool-to-evaluate-glaucoma-service-capacity
#17
Ruchika Batra, Hannah E Sharma, Ibrahim Elaraoud, Shabbir Mohamed
BACKGROUND: The National Patient Safety Agency (2009) publication advising timely follow-up of patients with established glaucoma followed several reported instances of visual loss due to postponed appointments and patients lost to follow-up. The Royal College of Ophthalmologists Quality Standards Development Group stated that all hospital appointments should occur within 15% of the intended follow-up period. AIM: To determine whether: 1. Glaucoma follow-up appointments at a teaching hospital occur within the requested time 2...
December 28, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/29282731/cognitive-behavioural-therapy-for-adult-attention-deficit-hyperactivity-disorder-a-proof-of-concept-randomised-controlled-trial
#18
A J Dittner, J Hodsoll, K A Rimes, A J Russell, T Chalder
OBJECTIVE: To investigate efficacy, patient acceptability and feasibility of formulation-based cognitive-behavioural therapy (CBT) for adults with attention-deficit hyperactivity disorder (ADHD). NICE guidelines for adult ADHD recommend further research into psychological treatments. METHOD: Sixty participants with adult ADHD were randomly allocated to treatment as usual (TAU) vs. TAU plus up to 16 sessions of individual formulation-based CBT for ADHD. RESULTS: Adding formulation-based CBT to TAU for ADHD significantly improved ADHD symptoms on the Barkley Current Symptoms Scale and scores on the Work and Social Adjustment Scale...
February 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29243813/antiepileptic-drug-monotherapy-for-epilepsy-a-network-meta-analysis-of-individual-participant-data
#19
REVIEW
Sarah J Nevitt, Maria Sudell, Jennifer Weston, Catrin Tudur Smith, Anthony G Marson
BACKGROUND: Epilepsy is a common neurological condition with a worldwide prevalence of around 1%. Approximately 60% to 70% of people with epilepsy will achieve a longer-term remission from seizures, and most achieve that remission shortly after starting antiepileptic drug treatment. Most people with epilepsy are treated with a single antiepileptic drug (monotherapy) and current guidelines from the National Institute for Health and Care Excellence (NICE) in the United Kingdom for adults and children recommend carbamazepine or lamotrigine as first-line treatment for partial onset seizures and sodium valproate for generalised onset seizures; however a range of other antiepileptic drug (AED) treatments are available, and evidence is needed regarding their comparative effectiveness in order to inform treatment choices...
December 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29231159/facet-joint-injections-for-non-specific-low-back-pain-a-feasibility-rct
#20
Saowarat Snidvongs, Rod S Taylor, Alia Ahmad, Simon Thomson, Manohar Sharma, Angela Farr, Deborah Fitzsimmons, Stephanie Poulton, Vivek Mehta, Richard Langford
BACKGROUND: Pain of lumbar facet-joint origin is a common cause of low back pain in adults and may lead to chronic pain and disability, with associated health and socioeconomic implications. The socioeconomic burden includes an inability to return to work resulting in loss of productivity in addition to direct and indirect health-care utilisation costs. Lumbar facet-joints are paired synovial joints between the superior and inferior articular processes of consecutive lumbar vertebrae and between the fifth lumbar vertebra and the sacrum...
December 2017: Health Technology Assessment: HTA
keyword
keyword
18494
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"