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https://www.readbyqxmd.com/read/27372029/testicular-seminoma-metastasis-to-duodenum-misdiagnosed-as-primary-duodenal-tumor
#1
Amer Hashim Al Ani, Hashim Amer Al Ani
INTRODUCTION: Testicular cancer is the most common malignancy in Males aged 15-35 years. Its incidence comprises 0.8% of all Male cancers worldwide, with a mortality rate of 0.1%. Rarely it metastasizes to the retroperitoneum and invades upper gastrointestinal tract (GIT). Complications like intestinal obstruction, hemorrhage, and perforation are usually present. PRESENTATION OF CASE: We report a 30 year-old male, presented to GIT unit with severe anemia due to upper GIT bleeding...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27246069/indications-for-gastrointestinal-endoscopy-in-childhood
#2
D Belsha, R Bremner, M Thomson
Endoscopic examination of the gastrointestinal tract (GIT) for diagnostics and therapy in children has evolved markedly over the last 20 or so years and is now usually undertaken by paediatric endoscopists. Updated diagnostic and management guidelines for common disorders including coeliac disease, gastro-oesophageal reflux disease, eosinophilic oesophagitis and inflammatory bowel disease highlight the central role of endoscopy. Therapeutic endoscopic approaches are also now widely available and further broaden the referral spectrum to include treatment of GIT bleeding, gastrostomy insertion, dilation of strictures and polypectomy...
May 31, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27170918/a-rare-cause-of-chronic-life-threatening-bleeding-in-a-girl-the-ulcerated-blind-loops
#3
Abhijeet D Sawant, Rasik Shah, Nitin Shah, Tarun Gupta
Ulceration in a blind loop can lead to massive gastrointestinal tract (GIT) bleeding. A 13-year old girl presented with symptomatic melena requiring repeated blood transfusion since childhood. She was an operated case of small bowel atresia in neonatal life. Her upper and lower gastrointestinal endoscopies were normal. Operation showed presence of multiple ulcers in two blind loops (parts of previous side to side anastomosis) and at the anastomotic site. She underwent resection and end-to-end anastomosis of the small bowel leading to complete resolution of melena and anemia...
May 2016: APSP Journal of Case Reports
https://www.readbyqxmd.com/read/26740206/synthesis-biological-evaluation-and-pharmacokinetic-studies-of-mefenamic-acid-n-hydroxymethylsuccinimide-ester-prodrug-as-safer-nsaid
#4
Asif Husain, Priyanka Ahuja, Aftab Ahmad, Shah A Khan
BACKGROUND: Non steroidal anti-inflammatory drugs are the most widely prescribed drugs to manage pain and inflammatory conditions, but their long term use is associated with gastrointestinal toxicity. OBJECTIVES: The study aimed to synthesize an ester-based prodrug of a non steroidal anti-inflammatory agent, mefenamic acid in order to improve the therapeutic index vis a vis to overcome the side effects such as gastrointestinal irritation and bleeding associated with the use of mefenamic acid...
2016: Medicinal Chemistry
https://www.readbyqxmd.com/read/26656368/the-value-of-u-s-to-determine-priority-for-upper-gastrointestinal-endoscopy-in-emergency-room
#5
Abd Elrazek Abd Elrazek, Hamdy Mahfouz, Khaled Abd Elazeem, Mohamed Fakhry, Emad Abd Elrazek, Mahmoud Foad, Mohamed Alboraie, Aly Ragab, Shazly Baghdady, Shymaa E Bilasy, Khaled Salama, Ramy Abdel Masseih, Mohamed Omar Amer, Sayed Hassaneen, Akshaya Srikanth Bhagavathula, Asim Ahmed Elnour, Saif K Al Nuaimi, Abdulla Shehab
In countries endemic for liver and GIT diseases, frequent emergency department (ED) patients contribute to a disproportionate number of visits consuming substantial amount of medical resources. One of the most frequent ED visits is patients who present with hypovolemic shock, abdominal pain, or confusion with or without signs of upper gastrointestinal bleeding (UGIB). The use of conventional two-dimensional ultrasound (2D-U/S) may provide immediate and useful information on the presence of esophageal varices, gastrointestinal tumors, and other GIT abnormalities...
December 2015: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26488559/withdrawn-prophylactic-steroids-for-pediatric-open-heart-surgery
#6
REVIEW
Mahmoud Elbarbary, Wedad H Madani, Suzanne Robertson-Malt
No abstract text is available yet for this article.
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26393188/blue-rubber-bleb-nevus-syndrome-in-a-child
#7
Sahana M Srinivas, R Premalatha
Blue rubber bleb nevus syndrome (BRBNS) is a rare vascular disorder with multiple haemangiomas in the skin, gastrointestinal tract and other visceral organs often associated with fatal bleeding and anaemia. We report a 13-year-old female child with multiple haemangiomas on skin and gastrointestinal tract with refractory anaemia. Awareness of this entity is necessary to prevent complications.
July 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26392825/small-bowel-sarcoma-a-rare-case-report
#8
Pramod Durgakeri, Anamitra Sarkar, Bianca Durgakeri
Sarcoma of the small bowel is an extremely rare type of small bowel malignancy and represents around 10 per cent of small bowel cancers. Usually asymptomatic, patients can present with chronic abdominal distention with pain and/or weight loss. Most pathologists now refer to small bowel sarcomas (SBS) as gastrointestinal stromal tumours as they are mesenchymal neoplasms believed to be derived from the interstitial cells of Cajal in the gastrointestinal tract. SBS can be highly vascular and commonly ulcerate and/or bleed...
2015: Australasian Medical Journal
https://www.readbyqxmd.com/read/26386802/incidence-and-consequence-of-major-bleeding-in-primary-percutaneous-intervention-for-st-elevation-myocardial-infarction-in-the-era-of-radial-access-an-analysis-of-the-international-randomized-acute-myocardial-infarction-treated-with-primary-angioplasty-and
#9
RANDOMIZED CONTROLLED TRIAL
Cyril Pellaton, Guillaume Cayla, Johanne Silvain, Uwe Zeymer, Marc Cohen, Patrick Goldstein, Kurt Huber, Charles Pollack, Mathieu Kerneis, Jean-Philippe Collet, Eric Vicaut, Gilles Montalescot
AIMS: The aims of the study are to compare the outcome with and without major bleeding and to identify the independent correlates of major bleeding complications and mortality in patients described in the ATOLL study. METHODS: The ATOLL study included 910 patients randomly assigned to either 0.5 mg/kg intravenous enoxaparin or unfractionated heparin before primary percutaneous coronary intervention. Incidence of major bleeding and ischemic end points was assessed at 1 month, and mortality, at 1 and 6 months...
October 2015: American Heart Journal
https://www.readbyqxmd.com/read/26375696/-new-trends-in-treatment-of-non-variceal-bleeding-in-the-upper-gastrointestinal-tract
#10
Radan Keil, Ladislav Douda
Acute upper gastrointestinal tract bleeding is a life-threatening incident in which a right diagnostic and therapeutic approach is necessary. Beside the standards in endoscopic hemostasis (adrenalin injection, hemostatic clips) there are some new technologies in endoscopic hemostasis.
July 2015: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/26374651/-neoadjuvant-therapy-for-tumors-of-the-upper-gastrointestinal-tract-complication-management
#11
REVIEW
I Gockel, A Hoffmeister, F Lordick
Recent studies could demonstrate that neoadjuvant chemotherapy and radiochemotherapy for esophageal and gastric cancer do not significantly increase the risk of postoperative morbidity and mortality as compared to surgery alone. With respect to patient safety and effectiveness of neoadjuvant concepts, quality assured performance of each treatment modality and close interdisciplinary cooperation play an important role. The majority of potential side effects and complications, which might occur during neoadjuvant therapy can be adequately controlled by correct prophylaxis and professional medical complication management...
November 2015: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/26369686/low-dose-aspirin-associated-upper-and-mid-gastrointestinal-tract-damage-and-gene-polymorphism
#12
REVIEW
Akiko Shiotani, Yoshihiko Fujita, Kazuto Nishio
The risk of gastrointestinal (GI) bleeding is increased in association with the use of low-dose aspirin (LDA). There are few studies of the association between genetic polymorphisms and the risks of aspirin-induced ulcer or its complications. Individuals with two single nucleotide polymorphisms (SNPs) of cyclooxygenase-1 (COX-1), A-842G and C50T, exhibit increased sensitivity to aspirin and lower prostaglandin synthesis capacity but the polymorphism lacked statistical significance in relation to an association with bleeding peptic ulcer...
2015: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/26369682/epidemiology-of-low-dose-aspirin-damage-in-the-lower-gastrointestinal-tract
#13
REVIEW
Carlos Sostres, Angel Lanas
Low dose aspirin (ASA), commonly defined as the cardiovascular (CV) dose of 75 to 325 mg daily, is one of the most widely prescribed drugs in the world and the cornerstone of therapy and prophylaxis for CV disease. However, the use of low dose ASA is well known to be associated with an increased risk of different upper and lower gastrointestinal (GI) complications, such as peptic ulceration and bleeding. In the recent past, clinical research was mainly focused on ASA-related injury of the upper GI tract. However, the introduction of new endoscopic techniques, such as capsule endoscopy and balloon-assisted endoscopy for the evaluation of small bowel lesions have resulted in an increasing interest among gastroenterologists about the side effects of ASA on the large and small bowel...
2015: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/26363105/perforated-meckel-s-diverticulum-in-an-adult-due-to-faecolith-a-case-report-and-review-of-literature
#14
Sunny Modi, Shant Kanapathy Pillai, Stefaan DeClercq
Meckel's diverticulum (MD) is a persistent remnant of the vitelointestinal duct and is present in 2% of population [1]. It is the most common congenital malformation of the gastrointestinal tract. It can present clinically as haemorrhage, diverticulitis, intussusception, chronic ulceration, intestinal obstruction and perforation. Complicated presentation, especially bleeding, tends to be more common in the paediatric group, whereas intestinal obstruction is more common in adults [2]. Patients with a perforation of Meckel's diverticulum by an enterolith are rare and may present with right iliac fossa pain, which mimics acute appendicitis...
2015: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/26351430/blue-rubber-bleb-nevus-syndrome-showing-vascular-skin-lesions-predominantly-on-the-face
#15
Ayumi Korekawa, Koji Nakajima, Takayuki Aizu, Hajime Nakano, Daisuke Sawamura
An 81-year-old Japanese man presented with dark blue papules and nodules on his face. There were multiple soft papules and nodules, dark blue in color, compressive, and ranging in size from 2 to 10 mm. A few similar lesions were seen on the patient's right dorsal second toe and right buccal mucosa. There were no skin lesions on his trunk and upper limbs. The patient's past history did not include gastrointestinal bleeding or anemia. Histopathological examination showed dilated vascular spaces lined by the normal epithelium extending beneath the dermis and into the subcutaneous fat...
May 2015: Case Reports in Dermatology
https://www.readbyqxmd.com/read/26347772/endoscopic-submucosal-dissection-for-gastric-subepithelial-tumors-a-single-center-experience
#16
Jin Sung Lee, Gwang Ha Kim, Do Youn Park, Jong Min Yoon, Tae Wook Kim, Jong Hun Seo, Bong Eun Lee, Geun Am Song
Background and Aims. Endoscopic submucosal dissection (ESD) has been accepted as a treatment modality for gastrointestinal epithelial tumors. Recently, ESD has been applied to resect subepithelial tumors (SETs) in the gastrointestinal tract, but clinical evidence on its efficacy and safety is limited. The aim of this study was to investigate the efficacy and safety of ESD for gastric SETs and to assess possible predictive factors for incomplete resection. Patients and Methods. Between January 2006 and December 2013, a total of 49 patients with gastric SET underwent ESD at our hospital...
2015: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/26344003/minimally-invasive-experience-for-the-treatment-of-gastrointestinal-stromal-tumours
#17
Fausto Famà, Giovanni Scibilia, Dario Lo Presti, Jessica Palella, Olivier Saint-Marc, Arnaud Piquard, Maria Gioffrè-Florio
Gastrointestinal stromal tumours are rare mesenchymal neoplasms, accounting less than 3% of all the gastrointestinal tumours, that may arise in all portions of the gastrointestinal tract but more frequently they involve stomach and small bowel. Generally are asymptomatic or slight symptomatic, although they may also cause acute clinical conditions. Histologically are characterised by a meshwork of spindle-like cells mixed with fibro-hyaline stroma. The immunohistochemical assessment, marked for a strong immunopositivity for CD117 antibodies, allows the differential diagnosis with others muscular, nervous and fibroblastic tumours...
July 2015: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/26333105/a-review-of-scientific-topics-and-literature-in-abdominal-radiology-in-germany-part-1-gastrointestinal-tract
#18
A G Schreyer, J Wessling, S Kinner, M S Juchems, K Holzapfel, T C Lauenstein, P Konietzke, L Grenacher
UNLABELLED: The working group for abdominal and gastrointestinal diagnosis is a group of the German Radiological Society (DRG) focusing clinically and scientifically on the diagnosis and treatment of the gastrointestinal tract with all parenchymatous abdominal organs. In addition to the clinical and scientific further development of abdominal radiology, the education of radiologists within this core discipline of radiology is one of the major aims. In this article we give an up-to-date literature review of scientific radiological topics especially covered by German radiologists...
February 2016: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/26305348/-acute-bleeding-into-the-gi-tract-a-surgical-diagnosis
#19
B East, J Hoch
INTRODUCTION: Patients with signs of acute bleeding into the gastrointestinal tract are hospitalized at intensive care units of surgical departments for organizational reasons. There is a growing proportion of those treated with various forms of antithrombotic therapy. From the onset of endoscopic methods of haemostasis, mortality is low and surgical treatment of these patients is rarely required. Their treatment takes up a lot of human and financial resources. The question remains, whether it would be possible to stop the volume growth or even reduce the number of these patients...
July 2015: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/26275738/concomitant-endometrial-and-gallbladder-metastasis-in-advanced-multiple-metastatic-invasive-lobular-carcinoma-of-the-breast-a-rare-case-report
#20
Kseniya Bezpalko, Mohamed A Mohamed, Leo Mercer, Michael McCann, Karim Elghawy, Kenneth Wilson
INTRODUCTION: At time of presentation, fewer than 10% of patients have metastatic breast cancer. The most common sites of metastasis in order of frequency are bone, lung, pleura, soft tissue, and liver. Breast cancer metastasis to the uterus or gallbladder is rare and has infrequently been reported in the English literature. PRESENTATION OF CASE: A 47 year old female with a recent history of thrombocytopenia presented with abnormal vaginal bleeding. Pelvic ultrasound revealed multiple uterine fibroids and endometrial curettings revealed cells consistent with lobular carcinoma of the breast...
2015: International Journal of Surgery Case Reports
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