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https://www.readbyqxmd.com/read/28239805/comparative-study-efficacy-of-closed-looptarget-controlled-infusion-of-cisatracurium-and-other-administration-methods-for-spinal-surgery-of-elderly-patients
#1
X-D Ma, J Yan, B-Z Dai, D-Q Kong, S-Y Du, B-P Li
OBJECTIVE: To observe the efficacy of traditional administration, continuous pump injection, and closed-loop target controlled infusion of cisatracurium to determine the optimal method of drug administration, and to establish the individualized and rational administration of muscle relaxants in elderly patients. PATIENTS AND METHODS: A total of 150 patients who underwent spinal surgery under tracheal intubation general anesthesia in our hospital from August 2013 to April 2015 were selected...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28239509/system-design-and-development-of-a-robotic-device-for-automated-venipuncture-and-diagnostic-blood-cell-analysis
#2
Max L Balter, Alvin I Chen, Alex Fromholtz, Alex Gorshkov, Tim J Maguire, Martin L Yarmush
Diagnostic blood testing is the most prevalent medical procedure performed in the world and forms the cornerstone of modern health care delivery. Yet blood tests are still predominantly carried out in centralized labs using large-volume samples acquired by manual venipuncture, and no end-to-end solution from blood draw to sample analysis exists today. Our group is developing a platform device that merges robotic phlebotomy with automated diagnostics to rapidly deliver patient information at the site of the blood draw...
October 2016: Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems
https://www.readbyqxmd.com/read/28239178/prevalence-and-characteristics-of-exercise-induced-bronchoconstriction-in-high-school-and-college-athletes-at-2-240-m-altitude
#3
Martín Becerril-Ángeles, Mario H Vargas, Leonardo Hernández-Pérez, Nancy Judith Rivera-Istepan, Rebeca Ivonne Pérez-Hidalgo, Ana Gabriela Ortega-González, Severino Rubio-Domínguez, María Cristina Rodríguez-Gutiérrez, Radamés Gaxiola-Cortés, Rodrigo Dosal-Ulloa, Laura Graciela Gochicoa-Rangel
BACKGROUND: Athletes practicing strenuous physical activities may develop exercise-induced bronchoconstriction (EIB). We aimed to determine the prevalence and features of this condition in Mexico City (altitude, 2,240 m). METHODS: In the present study, 208 high school and college athletes performed a standardized EIB test on a treadmill. RESULTS: Responses to exercise had large between-subject variability in all physiological parameters (forced expiratory volume in one second [FEV1], heart rate, blood oxygen saturation level [SpO2], blood pressure), with nearly similar proportions of subjects in whom FEV1 increased or decreased...
January 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28239036/short-term-subcutaneous-fondaparinux-and-oral-edoxaban-for-acute-venous-thromboembolism
#4
Shinji Hisatake, Takayuki Kabuki, Shunsuke Kiuchi, Takashi Oka, Shintaro Dobashi, Takahiro Fujii, Yoshihiro Iwasaki, Takanori Ikeda
BACKGROUND: No studies have compared treatment efficacy between subcutaneous (SC) fondaparinux and oral edoxaban, which are categorized as factor Xa inhibitors, for venous thromboembolism (VTE) in the acute phase, and only a limited number of imaging-based quantitative studies have evaluated treatment.Methods and Results:In this open-label, randomized study, 50 patients with acute non-massive pulmonary embolism (PE) and/or deep-vein thrombosis (DVT) were assigned to fondaparinux or edoxaban groups...
February 25, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28238959/superiority-of-robotic-surgery-for-cervical-cancer-in-comparison-with-traditional-approaches-a-systematic-review-and-meta-analysis
#5
REVIEW
Zhongyu Liu, Xiuli Li, Shuang Tian, Tongyu Zhu, Yuanqing Yao, Ye Tao
OBJECTIVES: To review the safety and effectiveness of da Vinci robotic surgery for cervical cancer in comparison with the traditional open surgery and conventional laparoscopic operation. METHODS: Based on Medline, the Cochrane library, Embase, and the Journal of Robotic Surgery prior to December 30st, 2015, we searched for controlled trials and observational studies. A systematic review with meta-analyses was conducted to compare the clinical efficacy between the da Vinci robotic surgery, open surgery, and laparoscopic surgery for cervical cancer...
February 23, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28238929/comparison-between-open-and-endovascular-repair-for-the-treatment-of-juxtarenal-abdominal-aortic-aneurysms-a-single-center-experience-with-midterm-results
#6
Koji Maeda, Takao Ohki, Yuji Kanaoka, Takeshi Baba, Kenjirou Kaneko, Kota Shukuzawa
PURPOSE: To evaluate the optimal treatment for juxtarenal abdominal aortic aneurysm (JAAA) we compared outcomes of open surgical repair (OSR) with endovascular aortic repair (EVAR) utilizing a variety of fenestrated and snorkel EVARs. METHODS: We evaluated overall survival, aneurysm-related death, re-intervention and renal impairment in 152 JAAAs retrospectively, excluding cases of aortic dissection and rupture. Cox models were used to assess survival and assessed postoperative dialysis rates following surgery...
February 23, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28238873/cell-salvage-used-in-scoliosis-surgery-is-it-really-effective
#7
REVIEW
Jia-Ming Liu, Bi-Qi Fu, Wen-Zhao Chen, Jiang-Wei Chen, Shan-Hu Huang, Zhi-Li Liu
BACKGROUND: Scoliosis surgery is usually associated with large volume of intraoperative blood loss and cell salvage is commonly used to filter and retranfusion autologous blood to patients. However, the efficacy of using cell salvage in scoliosis surgery is still controversial. OBJECTIVE: The purpose of this study is to make clear that intraoperative use of cell salvage is effective to decrease the volume of perioperative allogenic blood transfusion in scoliosis surgery...
February 23, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28238696/upper-body-subcutaneous-fat-is-associated-with-cardiometabolic-risk-factors
#8
Jane J Lee, Alison Pedley, Kate E Therkelsen, Udo Hoffmann, Joseph M Massaro, Daniel Levy, Michelle T Long
BACKGROUND: Upper body subcutaneous fat is a distinct fat depot that may confer increased cardiometabolic risk. We examined the cross-sectional associations between upper body subcutaneous fat volume and cardiometabolic risk factors. METHODS: Participants were from the Framingham Heart Study who underwent multi-detector computed tomography between 2008-2011. Sex-specific multivariable-adjusted regression analyses were conducted. Covariates included age, ethnicity, smoking status, alcohol intake, postmenopausal status, and hormone replacement therapy...
February 24, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28238403/increased-sputum-levels-of-thymus-and-activation-regulated-chemokine-in-children-with-asthma-not-eosinophilic-bronchitis
#9
M J Kim, H S Lee, I S Sol, M N Kim, J Y Hong, K E Lee, Y H Kim, K W Kim, M H Sohn, K-E Kim
BACKGROUND: Thymus and activation-regulated chemokine (TARC), a member of the CC chemokine family, plays a crucial role in Th2-specific inflammation. We aimed to determine the concentration of sputum TARC in children with asthma and eosinophilic bronchitis (EB) and its relation with eosinophilic inflammation, pulmonary function, and bronchial hyper-responsiveness. METHODS: In total, 90 children with asthma, 38 with EB, and 45 control subjects were enrolled. TARC levels were measured in sputum supernatants using an ELISA...
February 18, 2017: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/28238301/the-impact-of-hemocoagulase-for-improvement-of-coagulation-and-reduction-of-bleeding-in-fracture-related-hip-hemiarthroplasty-geriatric-patients-a-prospective-single-blinded-randomized-controlled-study
#10
Meiguang Qiu, Xuming Zhang, Hongru Cai, Zhixian Xu, Hao Lin
BACKGROUND: Uncontrolled bleeding is associated with poor outcomes and mortality in geriatric patients undergoing hemiarthroplasty. Hemocoagulase agkistrodon is a hemocoagulative, anti-hemorrhagic enzyme complex from Deinagkistrodon acutus snake venom. This study aimed to investigate the efficacy of hemocoagulase agkistrodon on coagulation and bleeding outcomes in fracture-related hemiarthroplasty. PATIENTS AND METHODS: This was a prospective, single-blinded, randomized controlled trial carried out between October 2013 and September 2014 in 96 geriatric patients undergoing hemiarthroplasty for unilateral femoral neck fracture...
November 27, 2016: Injury
https://www.readbyqxmd.com/read/28238183/associations-between-trace-elements-and-clinical-health-parameters-in-the-north-pacific-loggerhead-sea-turtle-caretta-caretta-from-baja-california-sur-mexico
#11
César Paúl Ley-Quiñónez, Natalia Alejandra Rossi-Lafferriere, Teresa Leticia Espinoza-Carreon, Catherine Edwina Hart, Sherwood Hoyt Peckham, Alfredo Alonso Aguirre, Alan Alfredo Zavala-Norzagaray
This study investigated selected trace elements toxicity in sea turtles Caretta caretta population from Baja California Sur (BCS), Mexico, by analyzing associations among Zn, Se, Cu, As, Cd, Ni, Mn, Pb, and Hg with various biochemical parameters (packed cell volume, leukocytes, and selected blood parameters), and whether their concentrations could have an impact on the health status of sea turtles. Blood samples from 22 loggerhead (C. caretta) sea turtles from BCS, Mexico, were collected for trace elements on biochemistry parameter analyses...
February 25, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28238111/use-of-fentanyl-in-adolescents-with-clinically-severe-obesity-undergoing-bariatric-surgery-a-pilot-study
#12
Janelle D Vaughns, Victoria C Ziesenitz, Elaine F Williams, Alvina Mushtaq, Ricarda Bachmann, Gisela Skopp, Johanna Weiss, Gerd Mikus, Johannes N van den Anker
BACKGROUND: The number of obese pediatric patients requiring anesthesia is rapidly increasing. Although fentanyl is a commonly used narcotic during surgery, there are no pharmacokinetic (PK) data available for optimal dosing of fentanyl in adolescents with clinically severe obesity. MATERIALS AND METHODS: An institutional review board-approved exploratory pilot study was conducted in six adolescents aged 14-19 years undergoing bariatric surgery. Mean total body weight (TBW) and mean BMI were 137...
February 25, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28237983/effects-of-cardiac-function-with-postoperative-arteriovenous-fistula-blood-flow-in-patients-with-hemodialysis
#13
Keiichi Wakabayashi, Hiroaki Io, Junichiro Nakata, Hirotaka Nakamoto, Michiko Sato, Yu Sasaki, Yoshio Shimizu, Satoshi Horikoshi, Yasuhiko Tomino, Yusuke Suzuki
BACKGROUND/AIMS: This study was aimed at evaluating the effect of cardiac function with postoperative arteriovenous fistula (AVF) blood flow in hemodialysis (HD) patients. METHODS: A total of 45 HD patients were examined at the Juntendo University Hospital. The AVF blood flow was measured using ultrasonography, and the cardiac function was measured using echocardiography. Correlation between these parameters and the rate of change in body weight (BW) was analyzed...
February 25, 2017: Blood Purification
https://www.readbyqxmd.com/read/28237973/modulatory-effects-of-melatonin-and-vitamin%C3%A2-%C3%A2-c-on-oxidative-stress-mediated-haemolytic-anaemia-and-associated-cardiovascular-dysfunctions-in-rats
#14
Temitayo Olabisi Ajibade, Ademola Adetokunbo Oyagbemi, Ladoke A Durotoye, Temidayo Olutayo Omóbòwálé, Ebunoluwa Racheal Asenuga, Funsho Olakitike Olayemi
Background Phenylhydrazine (PHE) in experimental animal models has been widely reported to cause haemolytic anaemia, via the induction of oxidative stress and thus causing deleterious cardiovascular complications. Hence, this study was designed to evaluate the possible modulatory role of melatonin (MLT) or vitamin C when co-administered with PHE. Methods Anaemia was established with PHE administration. MLT or vitamin C was co-administered with PHE. Haematological parameters, markers of oxidative stress, enzymic and non-enzymic antioxidants, blood pressure and electrocardiograms were assessed...
February 25, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28237937/investigation-of-viscoelasticity-in-the-relationship-between-carotid-artery-blood-pressure-and-distal-pulse-volume-waveforms
#15
Jong Chan Lee, Zahra Ghasemi, Chang-Sei Kim, Hao-Min Cheng, Chen-Huan Chen, Shih-Hsien Sung, Ramakrishna Mukkamala, Jin-Oh Hahn
We investigated the relationship between carotid artery blood pressure (BP) and distal pulse volume waveforms (PVRs) via subject-specific mathematical modeling. We conceived three physical models to define the relationship: a tube-load model augmented with a gain (TLG), Voigt (TLV) and standard linear solid (TLS) models. We compared these models using PVRs measured via BP cuffs at an upper arm and an ankle as well as carotid artery tonometry waveform collected from 133 subjects. At both upper arm and ankle, PVR was related to carotid artery tonometry by TLV and TLS models better than by TLG model; when root-mean-squared over all the subjects, the systolic and diastolic BP errors between measured carotid artery tonometry waveform and the one estimated from distal PVR reduced from 4...
February 22, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28237924/bayesian-estimation-of-intrinsic-tissue-oxygenation-and-perfusion-from-rgb-images
#16
Geoffrey Jones, Neil Clancy, Yusuf Helo, Simon Arridge, Dan Elson, Danail Stoyanov
Multispectral imaging (MSI) can potentially assist the intra-operative assessment of tissue structure, function and viability, by providing information about oxygenation. In this paper, we present a novel technique for recovering intrinsic MSI measurements from endoscopic RGB images without custom hardware adaptations. The advantage of this approach is that it requires no modification to existing surgical and diagnostic endoscopic imaging systems. Our method uses a radiometric colour calibration of the endoscopic camera's sensor in conjunction with a Bayesian framework to recover a per-pixel measurement of the total blood volume (THb) and oxygen saturation (SO2) in the observed tissue...
February 20, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28237681/assessment-of-distribution-of-ventilation-and-regional-lung-compliance-by-electrical-impedance-tomography-in-anaesthetized-horses-undergoing-alveolar-recruitment-manoeuvres
#17
Tamas D Ambrisko, Johannes Schramel, Klaus Hopster, Sabine Kästner, Yves Moens
OBJECTIVE: To examine changes in the distribution of ventilation and regional lung compliances in anaesthetized horses during the alveolar recruitment manoeuvre (ARM). STUDY DESIGN: Experimental study in which a series of treatments were administered in a fixed order on one occasion. ANIMALS: Five adult Warmblood horses. METHODS: Animals were anaesthetized (xylazine, midazolam-ketamine, isoflurane), placed in dorsal recumbency and ventilated with 100% oxygen using peak inspiratory pressure (PIP) and positive end-expiratory pressure (PEEP) of 20 cmH2O and 0 cmH2O, respectively...
January 12, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28237482/effects-of-the-hydro-ethanolic-extract-of-marrubium-vulgare-in-female-rats
#18
Rim Aouni, Mossadok Ben Attia, Mohamed Habib Jaafoura, Amina Bibi-Derbel, Mustapha Haouari
OBJECTIVE: To evaluate the effects of ethanol-water (80:20) extract of Marrubium vulgare (M. vulgare) on the hematological parameters, macroscopic and histological aspects of the uterus and fetus in non-pregnant and pregnant rats. METHODS: Female rats were divided into 4 equal groups (n = 9), group N (normal rats) and group G (pregnant rats) considered as control groups, group NE (normal rats treated with the ethanol-water (80:20, v/v) extract of M. vulgare) and group GE (pregnant rats treated with the extract)...
February 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28237342/changes-of-plasma-concentrations-of-insulin-like-peptide-3-and-testosterone-and-their-association-with-scrotal-circumference-during-pubertal-development-in-male-goats
#19
M A Hannan, N Kawate, Y Fukami, W W P N Weerakoon, E E Büllesbach, T Inaba, H Tamada
Insulin-like peptide 3 (INSL3) has been used as a testis-specific biomarker for puberty in several species, but the secretory profile of INSL3 during pubertal development in small ruminants is unknown. Here we sought to determine the age-related changes in the plasma concentrations of INSL3 and testosterone and their association with scrotal circumference during pubertal development in five male Shiba goats. Blood samples and scrotal circumference measurement were taken every 2 weeks from week 10 to week 52 of each goat's lifespan...
April 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28236850/intermittent-hypoxia-as-a-means-to-improve-aerobic-capacity-in-type-2-diabetes
#20
R J Leone, S Lalande
Physical inactivity and a low maximal aerobic capacity (VO2max) strongly predict morbidity and mortality in patients with type 2 diabetes (T2D). Patients with T2D have a reduced VO2max when compared with healthy individuals of similar age, weight, and physical activity levels, and this lower aerobic capacity is usually attributed to a reduced oxygen delivery to the working muscles. The oxygen carrying capacity of the blood, as well as increases in cardiac output and blood flow, contribute to the delivery of oxygen to the active muscles during exercise...
March 2017: Medical Hypotheses
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