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Sexuality and cardiovascular disease

Sarvenaz Sabouri-Rad, Sara Sabouri-Rad, Amirhossein Sahebkar, Zahra Tayarani-Najaran
Ginseng has gained fame as one of the most popular herbs originating from Eastern countries. Among different species which are known as ginseng, Panax ginseng C. A. Mey. (Korean or Asian ginseng) is the most frequently used one. Ginsenosides have been proposed to account for most of the biological activities of ginseng. The widely appreciated health-promoting effect of ginseng pertains to the beneficial effects of this plant against immune, cardiovascular and sexual diseases and cancer. In addition, there are some new aspects of the pharmacological activity of this plant which justify its use in dermatologic diseases...
October 21, 2016: Current Pharmaceutical Design
Rebecca C Thurston, Yuefang Chang, Emma Barinas-Mitchell, Roland von Känel, J Richard Jennings, Nanette Santoro, Doug P Landsittel, Karen A Matthews
OBJECTIVES: A childhood history of abuse or neglect may be associated with elevated adult cardiovascular disease (CVD) risk. No studies have examined associations between child abuse/neglect and subclinical CVD using a validated measure of abuse and neglect. We hypothesized that midlife women with a history of childhood abuse or neglect would have increased subclinical CVD beyond standard CVD risk factors. We tested moderation of associations by sleep, hot flashes, and race/ethnicity...
October 19, 2016: Psychosomatic Medicine
Peter Giovannini, Melanie-Jayne R Howes, Sarah E Edwards
The data described in this article is related to the review article "Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: a review" (Giovannini et al., 2016) [1]. We searched publications on the useful plants of Central America in databases and journals by using selected relevant keywords. We then extracted reported uses of medicinal plants within the disease categories: diabetes mellitus, kidney disease, urinary problems, skin diseases and infections, cardiovascular disease, sexual dysfunction, vision loss, and nerve damage...
June 2016: Data in Brief
G Andres Contreras, Kyan Thelen, Nadia Ayala-Lopez, Stephanie W Watts
There are sex associated differences in the risk for cardiovascular comorbidities in obesity and metabolic syndrome. A common clinical finding in these diseases is the expansion of perivascular adipose tissues (PVAT) which is associated with alterations in their role as regulators of vessel function. PVAT hyperplasia and hypertrophy are dependent on the biology of populations of adipocyte progenitor cells (APC). It is currently unclear if PVAT enlargement diverges between males and females and the mechanisms linking APC biology with sexual dimorphism remain poorly understood...
October 2016: Physiological Reports
Luboslav Stárka
Subnormal levels of testosterone are frequently found in men of higher age category. Hypogonadal men have lower life expectancy than men with full androgenization and cardiovascular disease, obesity or diabetes is often associated with hypotestosteronemia. Low testosterone level is risk factor for these diseases. However, until now it is not clear whether testosterone deficiency is a cause or consequence of atherosclerosis or metabolic syndrome. A handful of symptoms and metabolic risk markers in hypogonadal men can be ameliorated by testosterone supplementation...
2016: Vnitr̆ní Lékar̆ství
Giuseppe Sangiorgi, Riccardo Colantonio, Gabriele Antonini, Antonio Savino, Massimiliano Sperandio
Erectile dysfunction (ED) is defined as the inability to get and maintain a sufficient erection to ensure an acceptable sexual activity for the subject and the partner. Although ED does not represent per se a serious disease, it carries a notable and severe influence on quality of life, with significant implications on familiar and social relationship; DE may cause depression, shame, impairment of personal esteem and relational problems. Among many possible etiologies of ED, atherosclerotic disease of penile arteries represents one of the most frequent causes, so it should always be looked for in patients with multiple risk factors for cardiovascular disease or an established coronary or peripheral artery disease...
October 2016: Giornale Italiano di Cardiologia
Nasser M Al-Daghri, Majed S Alokail, Antigoni Manousopoulou, Ashley Heinson, Omar Al-Attas, Yousef Al-Saleh, Shaun Sabico, Sobhy Yakout, Christopher H Woelk, George P Chrousos, Spiros D Garbis
BACKGROUND: Overweight adults are at increased risk for cardiovascular disease and vitamin D deficiency, whereas an important feature to vitamin D physiology is its sex dependence. The aim of this study was to examine whether vitamin D status improvement exerts a sexually dimorphic effect on serum proteins associated with cardiovascular risk among overweight adults. METHODS: Unprocessed serum from age- and BMI-matched men (n=26) and pre-menopausal women (n=24) with vitamin D deficiency and after they achieved sufficiency through a 12-month nutritional intervention was analyzed using our previously published depletion-free, quantitative proteomics method...
October 11, 2016: European Journal of Clinical Investigation
J Mc Sharry, P J Murphy, M Byrne
BACKGROUND: Decreased sexual activity and sexual problems are common among people with cardiovascular disease, negatively impacting relationship satisfaction and quality of life. International guidelines recommend routine delivery of sexual counselling to cardiac patients. The Cardiac Health and Relationship Management and Sexuality (CHARMS) baseline study in Ireland found, similar to international findings, limited implementation of sexual counselling guidelines in practice. The aim of the current study was to develop the CHARMS multi-level intervention to increase delivery of sexual counselling by healthcare professionals...
October 10, 2016: Implementation Science: IS
Jae-Ho Yoo
The menarcheal age of Korean women has been rapidly decreasing for the last 50 years, and the average menarcheal age of women born in the 1990s is approaching 12.6 years. In addition, interest in early puberty has been increasing recently owing to the rapid increase in precocious puberty. Generally, out of concern for short stature and early menarche, idiopathic central precocious puberty in female adolescents is treated with gonadotropin-releasing hormone analogs. Studies to date have described the association between early menarche and psychosocial problems such as delinquency and risky sexual behavior, as well as physical health problems such as obesity, diabetes, cardiovascular diseases, and breast cancer throughout the lifespan of women...
September 2016: Korean Journal of Pediatrics
M F Garrido-Oyarzún, C Castelo-Branco
The increase in cancer incidence in younger people and the significant improvement in long and permanent remission have brought concern about their reproductive future and quality of life. Up to two-thirds of adult female patients undergoing chemotherapy for malignancies eventually develop premature ovarian failure. This condition is related to many complaints including vasomotor symptoms, osteoporosis, increased risk of cardiovascular diseases, sexual dysfunction, and infertility. Therefore, protection against iatrogenic infertility and loss of endocrine ovarian function caused by chemotherapy is currently of high priority...
September 17, 2016: Climacteric: the Journal of the International Menopause Society
Matthew Lee Smith, Heather Honoré Goltz, Audry S Motlagh, SangNam Ahn, Caroline D Bergeron, Marcia G Ory
PURPOSE: This study aims to identify socio-demographic and health behavior factors associated with cardiovascular disease (CVD) diagnosis and patient-physician communication concerning sexual issues among older Veterans. METHODS: Cross-sectional data were collected from 635 male Veterans over age 55 years as part of the 2010 National Social Life, Health and Aging Project, a nationally-representative, population-based study of community-dwelling older Americans. Two independent logistic regression analyses were performed...
October 2016: Maturitas
Ulrich T Egle, Matthias Franz, Peter Joraschky, Astrid Lampe, Inge Seiffge-Krenke, Manfred Cierpka
In the last decade strong empirical evidence from several long-term studies supports the conclusion that physical and sexual abuse as well as emotional deprivation in childhood make people significantly more vulnerable to mental and functional disorders across their lifetime. Additionally, an increased vulnerability to several somatic disorders (cardiovascular disorders, type-2-diabetes, hepatitis, chronic obstructive pulmonary disease (COPD), immunological and pain disorders, pharynx and lung cancer) was demonstrated - most of them with a reduced life expectancy...
October 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Mark A Moyad, Robert U Newton, Ulf W Tunn, Damian Gruca
Improved diagnosis and treatment regimens have resulted in greater longevity for men with prostate cancer. This has led to an increase in both androgen deprivation therapy (ADT) use and duration of exposure, and therefore to its associated adverse effects, such as sexual dysfunction, osteoporosis, reduced muscle mass, increased fat mass, and increased incidence of cardiovascular disease and type 2 diabetes. Given that the adverse effects of ADT are systemic, often debilitating, and difficult to treat, efforts continue in the development of new strategies for long-term management of prostate cancer...
2016: Research and Reports in Urology
Matthew M Burg, Robert Soufer
Post-traumatic stress disorder (PTSD) is a disabling condition that develops consequent to trauma exposure such as natural disasters, sexual assault, automobile accidents, and combat that independently increases risk for early incident cardiovascular disease (CVD) and cardiovascular (CV) mortality by over 50 % and incident hypertension risk by over 30 %. While the majority of research on PTSD and CVD has concerned initially healthy civilian and military veteran samples, emerging research is also demonstrating that PTSD consequent to the trauma of an acute cardiac event significantly increases risk for early recurrence and mortality and that patient experiences in the clinical pathway that are related to the emergency department environment may provide an opportunity to prevent PTSD onset and thus improve outcomes...
October 2016: Current Cardiology Reports
S Clifton, W Macdowall, A J Copas, C Tanton, B G Keevil, D M Lee, K R Mitchell, N Field, P Sonnenberg, J Bancroft, C H Mercer, A M Wallace, A M Johnson, K Wellings, Fcw Wu
CONTEXT: Salivary testosterone (Sal-T) measurement by LC-MS/MS resents the opportunity to examine health correlates of Sal-T in a large-scale population survey. OBJECTIVE: To examine associations between Sal-T and health-related factors in men and women aged 18-74 years. DESIGN & SETTING: Morning saliva samples were obtained from participants in a cross-sectional probability-sample survey of the general British population ('Natsal-3'). Self-reported health and lifestyle questions were administered as part of a wider sexual health interview...
August 23, 2016: Journal of Clinical Endocrinology and Metabolism
Ana I Mora-Urda, María Del Carmen B Molina, José G Mill, Pilar Montero-López
Carotid-femoral pulse wave velocity (cfPWV) measurement is an appropriate method for determining arterial stiffness and is a useful tool for early detection of cardiovascular disease. However, the lack of reference values due to the difficulty in accessing healthy child populations, among other causes, has limited its use in clinical practice. The aim of this study was to create reference cfPWV percentile curves for healthy children. The initial sample consisted of 350 girls and boys aged 8 to 11 years. The cfPWV per age and sex were generated using the lambda-mu-sigma (LMS) technique...
August 17, 2016: Journal of Clinical Hypertension
Ilaria Campesi, Stefano Occhioni, Giampiero Capobianco, Marco Fois, Andrea Montella, Salvatore Dessole, Flavia Franconi
Sex has largely been neglected in cell studies. Therefore, we investigated the occurrence of sexual dimorphism in human umbilical artery smooth muscle cells (HUASMCs). In particular, we investigated the existence of sex differences in basal and in drug-induced autophagy, a process involved in cardiovascular diseases. HUASMCs were isolated from healthy and normal weight male and female newborns (MHUASMCs and FHUASMCs, respectively). Expression of the primary molecules involved in the autophagic process [beclin-1 and microtubule-associated protein 1 light chain 3 (LC3)], and PmTOR were detected using western blotting in basal conditions, after serum starvation, rapamycin and verapamil treatments...
August 10, 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
Pelin Batur, Natalie Bowersox, Megan McNamara
The clinical update serves as a brief review of recently published, high-impact, and potentially practice-changing journal articles summarized for our readers. Topics include menopause, sexual dysfunction, breast health, contraception, osteoporosis, and cardiovascular disease. In this clinical update, we selected recent publications relevant to the use of contraceptive methods. We highlight articles on continuation rates of long-acting reversible contraception versus nonlong-acting methods, updated risks of intrauterine devices, use of estrogen-containing contraceptives during anticoagulation for venous thromboembolic events, and the efficacy of oral and emergency contraception in women with elevated body mass index...
August 2016: Journal of Women's Health
Giuseppe Morgia, Giorgio Ivan Russo, Andrea Tubaro, Roberto Bortolus, Donato Randone, Pietro Gabriele, Fabio Trippa, Filiberto Zattoni, Massimo Porena, Vincenzo Mirone, Sergio Serni, Alberto Del Nero, Giancarlo Lay, Umberto Ricardi, Francesco Rocco, Carlo Terrone, Arcangelo Pagliarulo, Giuseppe Ludovico, Giuseppe Vespasiani, Maurizio Brausi, Claudio Simeone, Giovanni Novella, Giorgio Carmignani, Rosario Leonardi, Paola Pinnarò, Ugo De Paula, Renzo Corvò, Raffaele Tenaglia, Salvatore Siracusano, Giovanna Mantini, Paolo Gontero, Gianfranco Savoca, Vincenzo Ficarra
OBJECTIVE: To analyze the prevalence of cardiovascular disease (CVD) and osteoporosis in patients treated with androgen deprivation therapy (ADT) for prostate cancer (PCa) but not adherent to European Association of Urology (EAU) guidelines. MATERIALS AND METHODS: The CHOosIng Treatment for Prostate CanCEr (CHOICE) study was an Italian multicenter, cross-sectional study conducted from December 2010 to January 2012. A total of 1386 patients treated with ADT for PCa (first prescription or renewal of ADT) were selected...
July 8, 2016: Urology
Jane A McElroy, Tess Gilbert, Elizabeth C Hair, Katherine J Mathews, Sarah Davis Redman, Amy Williams
PURPOSE: The purpose of this study was to describe fitness characteristics of metabolically healthy sexual minority women who are obese. METHODS: As part of the Healthy Weight in Lesbian and Bisexual Women Initiative funded by the U.S. Office on Women's Health, one site enrolled self-identified lesbian or bisexual women age 40 and older in a randomized controlled trial that evaluated interventions to improve health. Women with waist-to-height ratio of 0.5 or greater were classified as obese...
July 7, 2016: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
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