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Women and cardiovascular disease

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https://www.readbyqxmd.com/read/29931809/sex-differences-in-coronary-plaque-composition-evaluated-by-coronary-computed-tomography-angiography-in-newly-diagnosed-type-2-diabetes-association-with-low-grade-inflammation
#1
M Mrgan, J Gram, M Hecht Olsen, D Dey, B Linde Nørgaard, J Gram, N P Rønnow Sand
AIM: To determine differences in coronary plaque composition and inflammatory biomarkers between men and women with newly diagnosed Type 2 diabetes without known cardiovascular disease. METHODS: A total of 88 people with newly diagnosed (<1 year) Type 2 diabetes underwent contrast-enhanced coronary computed tomography angiography. Advanced coronary plaque analysis was performed using semi-automated software. Plasma concentrations of inflammatory biomarkers were determined...
June 22, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29931068/serum-25-hydroxyvitamin-d-concentrations-are-associated-with-computed-tomography-markers-of-subclinical-interstitial-lung-disease-among-community-dwelling-adults-in-the-multi-ethnic-study-of-atherosclerosis-mesa
#2
Samuel M Kim, Di Zhao, Anna J Podolanczuk, Pamela L Lutsey, Eliseo Guallar, Steven M Kawut, R Graham Barr, Ian H de Boer, Bryan R Kestenbaum, David J Lederer, Erin D Michos
Background: Activated vitamin D has anti-inflammatory properties. 25-Hydroxyvitamin D [25(OH)D] deficiency might contribute to subclinical interstitial lung disease (ILD). Objective: We examined associations between serum 25(OH)D concentrations and subclinical ILD among middle-aged to older adults who were free of cardiovascular disease at baseline. Methods: We studied 6302 Multi-Ethnic Study of Atherosclerosis (MESA) participants who had baseline serum 25(OH)D concentrations and computed tomography (CT) imaging spanning ≤ 10 y...
June 19, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29931040/chocolate-intake-and-heart-disease-and-stroke-in-the-women-s-health-initiative-a-prospective-analysis
#3
James A Greenberg, JoAnn E Manson, Marian L Neuhouser, Lesley Tinker, Charles Eaton, Karen C Johnson, James M Shikany
Background: Three recent meta-analyses found significant prospective inverse associations between chocolate intake and cardiovascular disease risk. Evidence from these meta-analyses suggests that such inverse associations may only apply to elderly individuals or those with pre-existing major chronic disease. Objective: We assessed the association between habitual chocolate intake and subsequent incident coronary heart disease (CHD) and stroke, and the potential effect of modification by age...
June 21, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29929865/mapping-the-gaps-gender-differences-in-preventive-cardiovascular-care-among-managed-care-members-in-four-metropolitan-areas
#4
Chloe E Bird, Michael Manocchia, Brooke Tomblin, Peggy Payne, Mahesh Kulakodlu, Emily Iacolo, Allen M Fremont
BACKGROUND: Prior research documents gender gaps in cardiovascular risk management, with women receiving poorer quality routine care on average, even in managed care systems. Although population health management tools and quality improvement efforts have led to better overall care quality and narrowing of racial/ethnic gaps for a variety of measures, we sought to quantify persistent gender gaps in cardiovascular risk management and to assess the performance of routinely used commercial population health management tools in helping systems narrow gender gaps...
June 1, 2018: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/29929840/a-review-of-the-associations-between-obstructive-sleep-apnea-and-hypertensive-disorders-of-pregnancy-and-possible-mechanisms-of-disease
#5
REVIEW
Jennifer E Dominguez, Ashraf S Habib, Andrew D Krystal
Obesity is prevalent among pregnant women in the United States; 15-20% of obese pregnant women have obstructive sleep apnea. The prevalence of obstructive sleep apnea increases along with body mass index, age and in the presence of other co-morbidities. Untreated obstructive sleep apnea in women is associated with a range of cardiovascular, pulmonary and metabolic co-morbidities; recent studies suggest that women with obstructive sleep apnea in pregnancy may be at significantly greater risk of entering pregnancy with chronic hypertension and/or of developing hypertensive disorders of pregnancy: gestational hypertension; preeclampsia; or eclampsia...
May 28, 2018: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29929608/influence-of-lifestyle-on-incident-cardiovascular-disease-and-mortality-in-patients-with-diabetes-mellitus
#6
Gang Liu, Yanping Li, Yang Hu, Geng Zong, Shanshan Li, Eric B Rimm, Frank B Hu, JoAnn E Manson, Kathryn M Rexrode, Hyun Joon Shin, Qi Sun
BACKGROUND: Evidence is limited regarding the impact of healthy lifestyle practices on the risk of subsequent cardiovascular events among patients with diabetes. OBJECTIVES: The purpose of this study was to examine the associations of an overall healthy lifestyle, defined by eating a high-quality diet (top two-fifths of Alternative Healthy Eating Index), nonsmoking, engaging in moderate- to vigorous-intensity physical activity (≥150 min/week), and drinking alcohol in moderation (5 to 15 g/day for women and 5 to 30 g/day for men), with the risk of developing cardiovascular disease (CVD) and CVD mortality among adults with type 2 diabetes (T2D)...
June 26, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29929107/in-utero-programming-and-early-detection-of-cardiovascular-disease-in-the-offspring-of-mothers-with-obesity
#7
REVIEW
Karolien Van De Maele, Roland Devlieger, Inge Gies
The offspring of women with obesity during their pregnancy are exposed to an altered intra-uterine environment. A subsequent influence on the cardiovascular development during fetal life is assumed. In the present thematic review, we report on the current knowledge about this early development of cardiovascular disease from fetal life until adolescence. Based on animal studies, different contributing mechanisms have been hypothesized that still need confirmation in human subjects. Insulin resistance, increased levels of leptin, chronic inflammatory state, perturbation of sympathetic tone and epigenetic modifications contribute to a suboptimal nutrient environment and changed hemodynamics...
June 9, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29928831/family-history-of-mi-smoking-and-risk-of-periodontal-disease
#8
Y H Yu, L Doucette-Stamm, J Rogus, K Moss, R Y L Zee, B Steffensen, P M Ridker, J E Buring, S Offenbacher, K Kornman, D I Chasman
Periodontal disease (PD) shares common risk factors with cardiovascular disease. Our hypothesis was that having a family history of myocardial infarction (FamHxMI) may be a novel risk factor for PD. Risk assessment based on FamHxMI, conditional on smoking status, was examined given the strong influence of smoking on PD. Exploratory analysis with inflammatory biomarkers and genetic determinants was conducted to understand potential mechanistic links. The Women's Genome Health Study (WGHS) is a prospective cohort of US female health care professionals who provided blood samples at baseline in the Women's Health Study, a 2 × 2 factorial clinical trial investigating vitamin E and aspirin in the prevention of cardiovascular disease and cancer...
June 1, 2018: Journal of Dental Research
https://www.readbyqxmd.com/read/29926995/prevalence-of-combined-and-noncombined-dyslipidemia-in-an-iranian-population
#9
Susan Darroudi, Maryam Saberi-Karimian, Maryam Tayefi, Soheil Arekhi, Ali Motamedzadeh Torghabeh, Seyed Mohammad Reza Seyedzadeh Sani, Mohsen Moohebati, Alireza Heidari-Bakavoli, Mahmoud Ebrahimi, Mahmoud Reza Azarpajouh, Mohammad Safarian, Gordon A Ferns, Habibollah Esmaeili, Mohammad Reza Parizadeh, Naghme Mokhber, Adeleh Mahdizadeh, Ali Asghar Mahmoudi, Amir Hossein Sahebkar, Majid Ghayour-Mobarhan
BACKGROUND: Combination of dyslipidemic phenotypes, including elevated plasma levels of low-density lipoprotein cholesterol (LDL-C), elevated plasma triglycerides (TG), and decreased low-density lipoprotein cholesterol (HDL-C) concentrations, is important because of the association of individual phenotypes with increased risk of cardiovascular disease (CVD). We investigated the prevalence of combined dyslipidemias and their effects on CVD risk in an Iranian large population. METHOD: A total of 9847 individuals were recruited as part of the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) cohort study...
June 21, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29925388/determination-of-aortic-stiffness-using-4d-flow-cardiovascular-magnetic-resonance-a-population-based-study
#10
Andreas Harloff, Hanieh Mirzaee, Thomas Lodemann, Paul Hagenlocher, Thomas Wehrum, Judith Stuplich, Anja Hennemuth, Jürgen Hennig, Sebastian Grundmann, Werner Vach
BACKGROUND: Increased aortic stiffness is an independent predictor of cardiovascular disease. Optimal measurement is highly beneficial for the detection of atherosclerosis and the management of patients at risk. Thus, it was our purpose to selectively measure aortic stiffness using a novel imaging method and to provide reference values from a population-based study. METHODS: One hundred twenty six inhabitants of Freiburg, Germany, between 20 and 80 years prospectively underwent 3 Tesla cardiovascular magnetic resonance (CMR) of the thoracic aorta...
June 21, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29924835/association-between-dry-eye-symptoms-and-suicidal-ideation-in-a-korean-adult-population
#11
Sun-Bi Um, Hyungseon Yeom, Na Hyun Kim, Hyeon Chang Kim, Hyung Keun Lee, Il Suh
PURPOSE: This study assessed the association of dry eyes with depression and suicidal ideation in a Korean adult population. METHODS: Data from 16408 participants (6972 men and 9436 women) aged ≥ 19 years included in the fifth Korea National Health and Nutrition Examination Survey, conducted from 2010-2012, were analyzed. For dry eyes, surveys of previous diagnosis of dry eye disease (DED) by an ophthalmologist and experience of subjective dry eye symptoms were separately used...
2018: PloS One
https://www.readbyqxmd.com/read/29924824/effect-of-adiposity-on-tissue-specific-adiponectin-secretion
#12
James Reneau, Matthew Goldblatt, Jon Gould, Tammy Kindel, Andrew Kastenmeier, Rana Higgins, L Rosemary Rengel, Katherine Schoyer, Roland James, Brittaney Obi, Andrea Moosreiner, Kay Nicholson, Daisy Sahoo, Srividya Kidambi
Circulating adiponectin levels are lower in individuals with increased BMI and central adiposity. However, they are paradoxically higher in those with peripheral adiposity. We hypothesized that adiponectin secretion from central and peripheral adipose tissue depots may be associated with adiposity levels and its distribution. A total of 55 subjects (69% women) undergoing elective abdominal surgery (mean age: 53 ± 13 years) were recruited. Health history, anthropometrics, and cardiovascular disease risk factor measurements were obtained...
2018: PloS One
https://www.readbyqxmd.com/read/29924373/factors-associated-with-hypertension-control-among-older-canadians
#13
Tracey Bushnik, Deirdre A Hennessy, Finlay A McAlister, Douglas G Manuel
BACKGROUND: In Canada, hypertension control is significantly less likely in older women taking antihypertensive medication than in older men. This study examines factors that may explain some of the differences in hypertension control between women and men. DATA AND METHODS: The analysis is based on data collected for 2,111 adults aged 60 to 79 who were treated for hypertension in the first four cycles of the Canadian Health Measures Survey. Hypertension, treatment and control were estimated based on measured systolic and diastolic blood pressure and on the Drug Identification Numbers of antihypertensive medications...
June 20, 2018: Health Reports
https://www.readbyqxmd.com/read/29923339/cardiovascular-disease-in-diabetes-type-2-current-concepts
#14
REVIEW
A Rosengren
Type 2 diabetes is a major and accelerating public health challenge. Between 1980 and 2014, a period of just 35 years, the number of adults with diabetes globally is estimated to have increased from 108 million to 422 million, due not only to sharply rising obesity rates, but also to increasing population size, and longer life expectancy. The increase in numbers is due to an increasing prevalence of diabetes worldwide, increasing population size, and longer life expectancy. Overall, worldwide age-standardized adult diabetes prevalence doubled from 4...
June 20, 2018: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29923323/sex-differences-in-management-and-outcomes-of-patients-with-type-2-diabetes-and-cardiovascular-disease-a-report-from-tecos
#15
Joakim Alfredsson, Jennifer B Green, Susanna R Stevens, Shelby D Reed, Paul W Armstrong, M Angelyn Bethel, Samuel S Engel, Darren K McGuire, Frans Van de Werf, Irene Hramiak, Harvey D White, Eric D Peterson, Rury R Holman
AIM: To examine sex differences in baseline characteristics and outcomes in patients with type 2 diabetes and atherosclerotic vascular disease. MATERIALS AND METHODS: Cox models were used to analyse the association between sex and outcomes in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS), a randomized, placebo-controlled trial assessing the impact of sitagliptin on cardiovascular (CV) outcomes in patients with type 2 diabetes and atherosclerotic vascular disease...
June 19, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29923126/sex-specific-considerations-in-women-with-aortic-stenosis-and-outcomes-after-transcatheter-aortic-valve-replacement
#16
REVIEW
Christos G Mihos, Sheila L Klassen, Evin Yucel
Aortic stenosis (AS) is the most common valvular disease in the elderly and is associated with poor outcomes. Transcatheter aortic valve replacement (TAVR) is an alternative to surgical aortic valve replacement (SAVR) in high-risk patients. Herein, we describe the gender-related differences in baseline characteristics and pathophysiologic response to severe AS, imaging considerations unique to females, and short- and long-term outcomes after TAVR. Women undergoing TAVR are older and frailer, have less cardiovascular comorbidities, smaller femoral artery size, better left ventricular systolic function, hypertrophied and small left ventricles leading to a higher incidence of paradoxical low-flow low-gradient AS, and a greater prevalence of porcelain aorta, smaller aortic annulus size, and lower coronary ostia heights...
June 19, 2018: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29923067/hypertensive-disorders-of-pregnancy-and-cardiovascular-diseases-current-knowledge-and-future-directions
#17
REVIEW
Thais Coutinho, Olabimpe Lamai, Kara Nerenberg
PURPOSE OF THE REVIEW: Cardiovascular diseases (CVDs) are the principal killers of women. In this review, we summarize data regarding CVD and mortality after hypertensive disorders of pregnancy (HDP), and highlight clinical, research and policy needs to mitigate this risk. RECENT FINDINGS: Robust data indicate that women with HDP have substantially higher risk of future CVD, with a 3.7-fold increase in the risk of chronic hypertension, a 4.2-fold increase in the risk of heart failure, an 81% increase in the risk of stroke, and double the risk of atrial arrhythmias, coronary heart disease, and mortality when compared to women with normotensive pregnancies...
June 19, 2018: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29922963/endocrine-treatment-of-aging-transgender-people
#18
REVIEW
Louis J Gooren, Guy T'Sjoen
High quality empirical data assessing morbidity and mortality and cancer incidence among transgender people are almost non-existent. Sex hormone treatment of conditions in older non-transgender people might as yet be taken as the best available analogy to hormone administration to aging transgender persons. Testosterone administration to transgender men carries little risk with regard to cardiovascular disease and cancer. A dose adaptation may be needed in men with a high hematocrit or cardiac insufficiency...
June 19, 2018: Reviews in Endocrine & Metabolic Disorders
https://www.readbyqxmd.com/read/29921571/marital-status-and-risk-of-cardiovascular-diseases-a-systematic-review-and-meta-analysis
#19
Chun Wai Wong, Chun Shing Kwok, Aditya Narain, Martha Gulati, Anastasia S Mihalidou, Pensee Wu, Mirvat Alasnag, Phyo Kyaw Myint, Mamas A Mamas
BACKGROUND: The influence of marital status on the incidence of cardiovascular disease (CVD) and prognosis after CVD is inconclusive. We systematically reviewed the literature to determine how marital status influences CVD and prognosis after CVD. METHODS: A search of MEDLINE and Embase in January 2018 without language restriction was performed to identify studies that evaluated the association between marital status and risk of CVD. Search terms related to both marital status and CVD were used and included studies had to be prospective in design...
June 19, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29921514/poorer-cardiovascular-health-is-associated-with-psychiatric-comorbidity-results-from-the-elsa-brasil-study
#20
Claudia Szlejf, Claudia K Suemoto, Itamar S Santos, Andre R Brunoni, Maria Angélica Nunes, Maria Carmen Viana, Sandhi Maria Barreto, Paulo A Lotufo, Isabela M Benseñor
BACKGROUND: Common psychiatric symptoms may hinder achieving ideal cardiovascular health (ICH). We aimed to investigate the association between the ICH score and psychiatric disorders in Brazilian adults. METHODS: In this cross-sectional analysis, 13,743 participants free of cardiovascular disease from the ELSA-Brasil study were assessed using the American Heart Association ICH score. Cardiovascular health was classified as poor (0-2 ideal metrics), intermediate (3-4 ideal metrics), and optimal (5-7 ideal metrics)...
June 12, 2018: International Journal of Cardiology
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