keyword
MENU ▼
Read by QxMD icon Read
search

Peripartum cardiomyopathy

keyword
https://www.readbyqxmd.com/read/29163363/human-prolactin-point-mutations-and-their-projected-effect-on-vasoinhibin-generation-and-vasoinhibin-related-diseases
#1
Jakob Triebel, Christin J Friedrich, Andreas Leuchs, Gonzalo Martínez de la Escalera, Carmen Clapp, Thomas Bertsch
Background: A dysregulation of the generation of vasoinhibin hormones by proteolytic cleavage of prolactin (PRL) has been brought into context with diabetic retinopathy, retinopathy of prematurity, preeclampsia, pregnancy-induced hypertension, and peripartum cardiomyopathy. Factors governing vasoinhibin generation are incompletely characterized, and the composition of vasoinhibin isoforms in human tissues or compartments, such as the circulation, is unknown. The aim of this study was to determine the possible contribution of PRL point mutations to the generation of vasoinhibins as well as to project their role in vasoinhibin-related diseases...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29153668/outcomes-and-mortality-in-parturient-and-non-parturient-patients-with-peripartum-cardiomyopathy-a-national-readmission-database-study
#2
Nisha Chhabra, Atul Gupta, Rachna Chibber, Mohammed Minhaj, Jennifer Hofer, Ariel Mueller, Avery Tung, Michael O'Connor, Barbara Scavone, Sarosh Rana, Sajid Shahul
BACKGROUND: Peripartum cardiomyopathy (PPCM) affects young females and mortality occurs after the peripartum period. Hospital readmissions for patients discharged with PPCM are poorly understood. The aim of this study was to evaluate differences in readmission rates, risk factors, and mortality in women with PPCM. METHODS: We conducted a retrospective cohort analysis using the Healthcare Cost and Utilization Project 2013 National Readmissions Database. From the database, we selected patients with PPCM to include patients discharged between January and November 2013...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29150149/pregnancy-and-heart-disease-pregnancy-associated-hypertension-and-peripartum-cardiomyopathy
#3
Tobias Jonathan Pfeffer, Denise Hilfiker-Kleiner
Cardiovascular diseases are major complications in pregnancy worldwide and the number of patients who develop cardiac problems during pregnancy is increasing. Pregnancy-associated hypertensive complications such as pre-eclampsia (PE) or peripartum cardiomyopathy (PPCM) are potentially life-threatening heart diseases emerging during pregnancy, under delivery or in the first postpartal months in previously healthy women. Both disease entities display substantial morbidity and mortality in the acute phase. Long-term effects are just beginning to be evaluated...
October 31, 2017: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29134367/imaging-of-cardiovascular-disease-in-pregnancy-and-the-peripartum-period
#4
REVIEW
Theodore Pierce, Meline Hovnanian, Sandeep Hedgire, Brian Ghoshhajra
Cardiovascular disease is an important cause of morbidity and mortality during pregnancy and the postpartum period. During pregnancy, the cardiovascular system undergoes extensive hemodynamic, hormonal, and microstructural changes which may exacerbate a preexisting underlying cardiovascular condition or predispose to cardiovascular complications not typically seen in young healthy women. Such conditions include spontaneous coronary artery dissection, atherosclerotic coronary artery disease, and peripartum cardiomyopathy...
November 14, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29132775/-maternal-deaths-due-to-cardiovascular-disease-results-from-the-french-confidential-enquiry-into-maternal-deaths-2010-2012
#5
D Chassard, E Verspyck
Between 2010 and 2012, 29 maternal deaths were caused by cardiovascular disease, i.e. an overall maternal mortality ratio of 1.2 per 100,000 live births. Deaths occurred in pre-existing heart disease (n=19), peripartum cardiomyopathy (n=5), or arterial rupture (n=5). Care was considered non-optimal in three of five patients with congenital heart disease and due to delayed management by specialized teams. Pregnant patients with heart disease should be considered to be at high risk of mortality or severe cardiovascular complications and therefore reoriented as soon as possible to a perinatal center with the expertise of these pathologies...
November 10, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29122930/peripartum-cardiomyopathy-diagnosis-and-management
#6
Alice M Jackson, Jonathan R Dalzell, Niki L Walker, Caroline J Coats, Pardeep S Jhund, Mark C Petrie
No abstract text is available yet for this article.
November 9, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29118838/a-complex-obstetric-case
#7
Michael Hoy, Kate Flavin, Venkat Prasad
A 33-year-old primigravida presented with severe sepsis, severe pre-eclampsia, peripartum cardiomyopathy and the haemolysis, elevated liver enzymes and low platelets syndrome manifesting over the course of 24 h causing a diagnostic conundrum and a difficult sequence of physiological problems to overcome. We describe a previously unreported sequence of events involving a pre-eclamptic, septic parturient to improve anaesthetic and intensive care physician awareness of confounding factors that complicate assessment and management of these patients...
August 2017: J Intensive Care Soc
https://www.readbyqxmd.com/read/29102365/pregnancy-in-women-with-a-cardiomyopathy-outcomes-and-predictors-from-a-retrospective-cohort
#8
Gilles Billebeau, Martin Etienne, Riadh Cheikh-Khelifa, Daniele Vauthier-Brouzes, Estelle Gandjbakhch, Richard Isnard, Jacky Nizard, Michel Komajda, Marc Dommergues, Philippe Charron
BACKGROUND: Pregnancies in women with pre-existing cardiomyopathies are considered at high risk for complications. However, few data are available to characterize their natural history and predict the outcome. AIMS: Our aim was to evaluate the prevalence and predictors of acute cardiac and obstetric events in women with a cardiomyopathy during pregnancy, excluding peripartum cardiomyopathy. METHODS: In this retrospective study in a referral centre for cardiomyopathies, we included 43 consecutive pregnancies in 36 women with dilated, hypertrophic, arrhythmogenic right ventricular or tachycardia-induced cardiomyopathy, or left ventricular non-compaction...
October 25, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29101003/fatal-accelerated-rejection-with-a-prominent-natural-killer-cell-infiltrate-in-a-heart-transplant-recipient-with-peripartum-cardiomyopathy
#9
Ali Javaheri, Amber R Wang, Eline Luning Prak, Priti Lal, Lee R Goldberg, Malek Kamoun
Accelerated rejection is uncommon after cardiac transplantation. The mechanism is hypothesized to be mediated by cytotoxic T cells and anti-HLA antibodies resulting from a memory response to the donor allograft in sensitized patients. A role for Natural Killer (NK) cell in cellular rejection has also been suggested. We report a case of fulminant accelerated rejection in a heart transplant recipient, with a history of peripartum cardiomyopathy (PPMC). The patient had no pre-transplant donor specific antibody and flow cytometric T and B cell crossmatches were negative...
October 31, 2017: Transplant Immunology
https://www.readbyqxmd.com/read/29079307/circulating-t-cell-subsets-monocytes-and-natural-killer-cells-in-peripartum-cardiomyopathy-results-from-the-multicenter-ipac-study
#10
Charles F McTiernan, Penelope Morel, Leslie T Cooper, Navin Rajagopalan, Vinay Thohan, Mark Zucker, John Boehmer, Biykem Bozkurt, Paul Mather, John Thornton, Jalal K Ghali, Karen Hanley-Yanez, James Fett, Indrani Halder, Dennis M McNamara
OBJECTIVE: Evaluate the hypothesis that the distribution of circulating immune cell subsets, or their activation state, is significantly different between PPCM and healthy postpartum (HP) women. BACKGROUND: Peripartum cardiomyopathy (PPCM) is a major cause of maternal morbidity and mortality and an immune-mediated etiology has been hypothesized. Cellular immunity, altered in pregnancy and the peripartum period, has been proposed to play a role in PPCM pathogenesis...
October 24, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29077664/a-case-report-of-recurrent-severe-peripartum-cardiomyopathy-complicated-by-factor-v-leiden-and-multiple-endocrine-neoplasia-type-1-a-management-conundrum
#11
Amanda M Kleiman, Jessica L Sheeran, Mohamed Tiouririne
Cardiovascular disease is the leading cause of peripartum death in the United States during pregnancy. The presence of concomitant diagnoses may complicate or conflict with the management of the primary cardiovascular diagnosis and further complicate pregnancy and delivery. We describe the management of a 29-year-old, gravida 5, para 1 woman with severe peripartum cardiomyopathy during this and a previous pregnancy complicated by multiple endocrine neoplasia type and factor V Leiden thrombophilia, limiting therapeutic options and contributing to considerable perioperative management challenges...
October 26, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29069030/clinical-outcomes-of-peripartum-cardiomyopathy-a-15-year-nationwide-population-based-study-in-asia
#12
Victor Chien-Chia Wu, Tien-Hsing Chen, Jih-Kai Yeh, Michael Wu, Cheng-Hui Lu, Shao-Wei Chen, Katie Pei-Hsuan Wu, Chun-Wen Cheng, Chih-Hsiang Chang, Kuo-Chun Hung, Ming-Shyan Chern, Fen-Chiung Lin, Ming-Shien Wen
Peripartum cardiomyopathy (PPCM) is the development of heart failure during late pregnancy to months postpartum with potential fatal outcome. However, the disease is not well-studied in Asia.We aimed to investigate the epidemiology and clinical outcomes of PPCM in Taiwan.Electronic medical records were retrieved from Taiwan National Health Insurance Research Database from 1997 to 2011. Patients with PPCM were separated into 3 groups based on the timing of diagnosis. Early: PPCM diagnosed first to ninth month of pregnancy...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29049825/comparison-of-clinical-characteristics-and-outcomes-of-peripartum-cardiomyopathy-between-african-american-and-non-african-american-women
#13
Olga Corazón Irizarry, Lisa D Levine, Jennifer Lewey, Theresa Boyer, Valerie Riis, Michal A Elovitz, Zolt Arany
Importance: Peripartum cardiomyopathy (PPCM) disproportionately affects women of African ancestry, but well-powered studies to explore differences in severity of disease and clinical outcomes are lacking. Objective: To compare the clinical characteristics, presentation, and outcomes of PPCM between African American and non-African American women. Design, Setting, and Participants: This retrospective cohort study using data from January 1, 1986, through December 31, 2016, performed at the University of Pennsylvania Health System, a tertiary referral center serving a population with a high proportion of African American individuals, included 220 women with PPCM...
November 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29049487/poor-outcomes-in-poor-patients-peripartum-cardiomyopathy-not-just-black-and-white
#14
Johann Bauersachs
No abstract text is available yet for this article.
November 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29024504/high-validity-of-cardiomyopathy-diagnoses-in-western-sweden-1989-2009
#15
Carmen Basic, Annika Rosengren, Sandra Lindström, Maria Schaufelberger
AIM: Hospital discharges with a diagnosis of cardiomyopathy have more than doubled in Sweden since 1987. We validated the cardiomyopathy diagnoses over this time period to investigate that the increase was real and not a result of improved recognition of the diagnosis and better diagnostic methods. METHODS AND RESULTS: Every fifth year from 1989 to 2009, records for all patients with a cardiomyopathy diagnosis were identified by searching the local registers in three hospitals in Västra Götaland, Sweden...
October 11, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29021419/what-should-be-generalized-diagnostic-markers-for-peripartum-cardiomyopathy
#16
COMMENT
Ichiro Sakuma, Toshihisa Anzai
No abstract text is available yet for this article.
October 25, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28936737/peripartum-cardiomyopathy-do-exosomes-play-a-role
#17
Huanyu Gu, Qiying Dai, Zhuyuan Liu, Hongbao Wang, Jianhua Yao, Lei Zhou
Peripartum cardiomyopathy (PPCM) refers to irreversible cardiomyocyte damage that occurs during the last month of pregnancy, or within 5 months after giving birth. It is characterized by systolic heart failure. This life-threatening condition is relatively uncommon, but the incidence has been climbing up. Because of its high mortality, it is crucial for physicians to have high suspicious for the disease. Studies have been done to search into specific lab test and treatment for PPCM. Therapies like anti-viral, anti-inflammatory and immunosuppression regimen have been explored...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28935576/myofilament-remodeling-and-function-is-more-impaired-in-peripartum-cardiomyopathy-compared-with-dilated-cardiomyopathy-and-ischemic-heart-disease
#18
Ilse A E Bollen, Elisabeth Ehler, Karin Fleischanderl, Floor Bouwman, Lanette Kempers, Melanie Ricke-Hoch, Denise Hilfiker-Kleiner, Cristobal Guillermo Dos Remedios, Martina Krüger, Aryan Vink, Folkert W Asselbergs, Karin Y van Spaendonck-Zwarts, Yigal M Pinto, Diederik W D Kuster, Jolanda van der Velden
Peripartum cardiomyopathy (PPCM) and dilated cardiomyopathy (DCM) show similarities in clinical presentation. However, although DCM patients do not recover and slowly deteriorate further, PPCM patients show either a fast cardiac deterioration or complete recovery. The aim of this study was to assess if underlying cellular changes can explain the clinical similarities and differences in the two diseases. We, therefore, assessed sarcomeric protein expression, modification, titin isoform shift, and contractile behavior of cardiomyocytes in heart tissue of PPCM and DCM patients and compared these with nonfailing controls...
September 19, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28934844/an-update-on-cardiomyopathies-immune-mediated-diseases-sarcoidosis-and-peripartum-and-hypertrophic-cardiomyopathies-during-pregnancy
#19
Thomas F Lüscher
No abstract text is available yet for this article.
September 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28934838/bromocriptine-for-the-treatment-of-peripartum-cardiomyopathy-welcome-on-board
#20
Mattia Arrigo, Alice Blet, Alexandre Mebazaa
No abstract text is available yet for this article.
September 14, 2017: European Heart Journal
keyword
keyword
18437
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"