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https://www.readbyqxmd.com/read/29238599/characterization-of-physiological-and-molecular-processes-associated-with-potato-response-to-zebra-chip-disease
#1
Chika C Nwugo, Venkatesan G Sengoda, Li Tian, Hong Lin
Transcriptional analyses identified molecular mechanisms associated with the response of leaf and root potato tissues to 'Candidatus. Liberibacter solanacearum' (Lso) infection, presumptive causal agent of zebra chip disease (ZC). Putative Lso infection affected several host processes including defense response-, regulation-, starch metabolism- and energy production-related processes. Interestingly, while proteinase inhibitors were strongly upregulated in leaf tissues, a concomitant downregulation was observed in root tissues...
2017: Horticulture Research
https://www.readbyqxmd.com/read/29234906/polyaniline-coated-activated-carbon-aerogel-sulfur-composite-for-high-performance-lithium-sulfur-battery
#2
Zhiwei Tang, Jinglin Jiang, Shaohong Liu, Luyi Chen, Ruliang Liu, Bingna Zheng, Ruowen Fu, Dingcai Wu
An activated carbon aerogel (ACA-500) with high surface area (1765 m2 g-1), pore volume (2.04 cm3 g-1), and hierarchical porous nanonetwork structure is prepared through direct activation of organic aerogel (RC-500) with a low potassium hydroxide ratio (1:1). Based on this substrate, a polyaniline (PANi)-coated activated carbon aerogel/sulfur (ACA-500-S@PANi) composite is prepared via a simple two-step procedure, including melt-infiltration of sublimed sulfur into ACA-500, followed by an in situ polymerization of aniline on the surface of ACA-500-S composite...
December 12, 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/29225764/sodium-chloride-accumulation-in-glycophyte-plants-with-cyanobacterial-symbionts
#3
Thomas George Allan Green, Leopoldo G Sancho, Ana Pintado, Dolores Saco, Soledad Martín, María Arróniz-Crespo, Miguel Angel Casermeiro, Maria Teresa de la Cruz Caravaca, Steven Cameron, Ricardo Rozzi
The majority of plant species are glycophytes and are not salt-tolerant and maintain low sodium levels within their tissues; if. high tissue sodium concentrations do occur, it is in response to elevated environmental salt levels. Here we report an apparently novel and taxonomically diverse grouping of plants that continuously maintain high tissue sodium contents and share the rare feature of possessing symbiotic cyanobacteria. Leaves of Gunnera magellanica in Tierra del Fuego always had sodium contents (dry weight basis) of around 4...
November 2017: AoB Plants
https://www.readbyqxmd.com/read/29225608/transcriptomic-profiling-and-physiological-responses-of-halophyte-kochia-sieversiana-provide-insights-into-salt-tolerance
#4
Long Zhao, Zongze Yang, Qiaobing Guo, Shun Mao, Shaoqiang Li, Fasheng Sun, Huan Wang, Chunwu Yang
Halophytes are remarkable plants that can tolerate extremely high-salinity conditions, and have different salinity tolerance mechanisms from those of glycophytic plants. In this work, we investigated the mechanisms of salinity tolerance of an extreme halophyte, Kochia sieversiana (Pall.) C. A. M, using RNA sequencing and physiological tests. The results showed that moderate salinity stimulated the growth and water uptake of K. sieversiana and, even under 480-mM salinity condition, K. sieversiana maintained an extremely high water content...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29223451/mineralization-in-newborn-calves-contributes-to-health-improve-the-antioxidant-system-and-reduces-bacterial-infections
#5
Patrícia Glombowsky, Aleksandro S da Silva, Natan M Soldá, Gabriela M Galli, Angelisa H Biazus, Gabriela Campigotto, Nathieli B Bottari, Rejane S Sousa, Maiara C Brisola, Lenita M Stefani, Matheus D Baldissera, Marta L R Leal, Vera M Morsch, Maria Rosa C Schetinger, Gustavo Machado
The first phase of life of dairy calves has elevated mortality indices linked with low immunity and sanitary challenges, mainly bacterial infections are involved in the pathogenesis of diarrhea, the leading cause of death. Also, other important problem is the nutritional deficiencies, such as the mineral deficiency. Thus, the aim of this study was to evaluate whether an intramuscular mineral supplementation based on selenium, copper, potassium, magnesium and phosphorus possess beneficial effects on health of dairy calves...
December 6, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29215966/effect-of-koh-activation-in-the-desulfurization-process-of-activated-carbon-prepared-by-sewage-sludge-corn-straw
#6
Fan Zeng, Xiaofeng Liao, Hui Hu, Li Liao
Series sludge-straw based activated carbons were prepared by sewage sludge and corn straw with potassium hydroxide activation, and the desulfurization performance of activated carbons were studied. To obtain the best desulfurization performance, the optimum ratio between the raw materials and the activator was investigated. The results showed that as the mass ratio of sewage sludge, corn straw and potassium hydroxide was 3:7:2, the activated carbon obtained the best breakthrough and saturation sulfur sorption capacity, which were 12...
December 7, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/29212920/phasic-and-tonic-cell-types-in-the-zebra-finch-auditory-caudal-mesopallium
#7
Andrew N Chen, C Daniel Meliza
The caudal mesopallium (CM) is a cortical-level area in the songbird auditory pathway where selective, invariant responses to familiar songs emerge. To characterize the cell types that perform this computation, we made whole-cell recordings from brain slices in juvenile zebra finches (Taeniopygia guttata) of both sexes. We found three groups of putatively excitatory neurons with distinct firing patterns. Tonic cells produced sustained responses to depolarizing step currents, phasic cells produced only a few spikes at the onset, and an intermediate group was also phasic but responded for up to a few hundred ms...
December 6, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29203397/pro-arrhythmic-effects-of-low-plasma-k-in-human-ventricle-an-illustrated-review
#8
REVIEW
Beatriz Trenor, Karen Cardona, Lucia Romero, Juan F Gomez, Javier Saiz, Sridharan Rajamani, Luiz Belardinelli, Wayne Giles
Potassium levels in the plasma, [K+]o, are regulated precisely under physiological conditions. However, increases (from approx. 4.5 to 8.0mM) can occur as a consequence of, e.g., endurance exercise, ischemic insult or kidney failure. This hyperkalemic modulation of ventricular electrophysiology has been studied extensively. Hypokalemia is also common. It can occur in response to diuretic therapy, following renal dialysis, or during recovery from endurance exercise. In the human ventricle, clinical hypokalemia (e...
November 24, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29203171/the-nlrp3-inflammasome-renders-cell-death-pro-inflammatory
#9
REVIEW
Moritz M Gaidt, Veit Hornung
NLRP3 is the most studied inflammasome sensor due to its crucial involvement in sterile and infection-triggered inflammation. Although its molecular mode of activation remains to be defined, it is well established that low intracellular potassium concentrations result in its activation. This functionality allows the classical NLRP3 pathway to serve as a highly sensitive, but non-specific surveillance mechanism responding to any type of perturbation that breaches plasma membrane integrity and the associated potassium-gradient across the membrane...
December 1, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/29202458/integrating-light-sheet-imaging-with-virtual-reality-to-recapitulate-developmental-cardiac-mechanics
#10
Yichen Ding, Arash Abiri, Parinaz Abiri, Shuoran Li, Chih-Chiang Chang, Kyung In Baek, Jeffrey J Hsu, Elias Sideris, Yilei Li, Juhyun Lee, Tatiana Segura, Thao P Nguyen, Alexander Bui, René R Sevag Packard, Peng Fei, Tzung K Hsiai
Currently, there is a limited ability to interactively study developmental cardiac mechanics and physiology. We therefore combined light-sheet fluorescence microscopy (LSFM) with virtual reality (VR) to provide a hybrid platform for 3D architecture and time-dependent cardiac contractile function characterization. By taking advantage of the rapid acquisition, high axial resolution, low phototoxicity, and high fidelity in 3D and 4D (3D spatial + 1D time or spectra), this VR-LSFM hybrid methodology enables interactive visualization and quantification otherwise not available by conventional methods, such as routine optical microscopes...
November 16, 2017: JCI Insight
https://www.readbyqxmd.com/read/29201383/an-autosomal-recessive-mutation-in-scl24a4-causing-enamel-hypoplasia-in-samoyed-and-its-relationship-to-breed-wide-genetic-diversity
#11
Niels C Pedersen, Bonnie Shope, Hongwei Liu
Background: Pure breeding of dogs has led to over 700 heritable disorders, of which almost 300 are Mendelian in nature. Seventy percent of the characterized mutations have an autosomal recessive mode of inheritance, indicative of positive selection during bouts of inbreeding primarily for new desired conformational traits. Samoyed suffer from several common complex genetic disorders, but up to this time only two X-linked and one autosomal dominant disorder have been identified. Previous studies based on pedigrees and SNP arrays have concluded that Samoyed breeders have done a good job in maintaining genetic diversity and avoiding excessive inbreeding...
2017: Canine Genetics and Epidemiology
https://www.readbyqxmd.com/read/29199586/health-and-risk-assessment-by-icp-oes-of-heavy-metals-and-trace-minerals-in-commercial-mushrooms-marketed-in-china
#12
Mengyi Huang, Huansong Zeng, Baojun Xu
The objectives of this study were to investigate mineral profiles of 35 species of edible mushrooms collected in China; we compared nutritional values and tolerable values with the official recommended daily intakes (RDIs), maximum intake limits, and provisional tolerable weekly intakes. A total of 19 minerals were detected in edible mushrooms by inductively coupled plasma optical emission spectrometry. The results showed that the mushroom samples had a low percentage of RDI for the minerals calcium, iron, magnesium, manganese, zinc, potassium, and sodium and a relatively higher percentage of RDI for copper and molybdenum...
2017: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29198641/hemodialysis-self-management-intervention-randomized-trial-hed-smart-a-practical-low-intensity-intervention-to-improve-adherence-and-clinical-markers-in-patients-receiving-hemodialysis
#13
Konstadina Griva, Mooppil Nandakumar, Jo-An H Ng, Kevin F Y Lam, Hayley McBain, Stanton P Newman
BACKGROUND: Poor adherence to treatment is common in hemodialysis patients. However, effective interventions for adherence in this population are lacking. Small studies of behavioral interventions have yielded improvements, but clinical effectiveness and long-term effects are unclear. STUDY DESIGN: Multicenter parallel (1:1) design, blinded cluster-randomized controlled trial. SETTING & PARTICIPANTS: Patients undergoing maintenance hemodialysis enrolled in 14 dialysis centers...
November 30, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29198575/voltammetric-determination-of-thujone-in-herbal-matrices-in-the-presence-of-triton-x-100
#14
Mateusz Kowalcze, Małgorzata Jakubowska
A simple, sensitive and rapid method of low concentration of thujone determination using Controlled Growth Mercury Drop Electrode and Differential Pulse Voltammetry was described. The reduction of thujone in phosphoric acid or potassium nitrate, involves a quasi-reversible and adsorption-controlled two-electron process. In voltammetric experiments the addition of ethanol and Triton X-100 is recommended. Experimental conditions such as composition of supporting electrolyte, concentration of Triton X-100 and operation parameters were established...
November 30, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/29196578/precision-therapy-for-epilepsy-due-to-kcnt1-mutations-a-randomized-trial-of-oral-quinidine
#15
Saul A Mullen, Patrick W Carney, Annie Roten, Michael Ching, Paul A Lightfoot, Leonid Churilov, Umesh Nair, Melody Li, Samuel F Berkovic, Steven Petrou, Ingrid E Scheffer
OBJECTIVE: To evaluate quinidine as a precision therapy for severe epilepsy due to gain of function mutations in the potassium channel gene KCNT1. METHODS: A single-center, inpatient, order-randomized, blinded, placebo-controlled, crossover trial of oral quinidine included 6 patients with severe autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) due to KCNT1 mutation. Order was block randomized and blinded. Four-day treatment blocks were used with a 2-day washout between...
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29194598/composition-granular-structure-and-pasting-properties-of-native-starch-extracted-from-plectranthus-edulis-oromo-dinich-tubers
#16
Tom Hellemans, Gifty Abera, Ingrid De Leyn, Paul Van der Meeren, Koen Dewettinck, Mia Eeckhout, Bruno De Meulenaer, Filip Van Bockstaele
Chemical composition, granular morphology and pasting properties of native starch extracted from tubers of Plectranthus edulis were analyzed. Starch was extracted from tubers of 6 accessions collected from 4 different areas in Ethiopia. Particle size analysis (PSA) and cryo-scanning electron microscope (cryo-SEM) imaging were used to examine the granular morphology and visualize the starch paste, respectively. Pasting properties, water absorption, and gelation capacity were compared. A wide range was found for the amylose (14...
December 1, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29191594/a-phase-ii-trial-of-carboplatin-plus-s-1-for-elderly-patients-with-advanced-non-small-cell-lung-cancer-with-wild-type-epidermal-growth-factor-receptor-the-okayama-lung-cancer-study-group-trial-1202
#17
Shoichi Kuyama, Nobuaki Ochi, Akihiro Bessho, Katsuyuki Hotta, Genyo Ikeda, Daizo Kishino, Toshio Kubo, Daijiro Harada, Nobukazu Fujimoto, Masamoto Nakanishi, Takahiro Umeno, Toshiaki Okada, Kenichi Chikamori, Tomoko Yamagishi, Kadoaki Ohashi, Eiki Ichihara, Nagio Takigawa, Mitsune Tanimoto, Katsuyuki Kiura
INTRODUCTION: S-1 is an oral fluoropyrimidine-based combination of tegafur, gimeracil, and oteracil potassium. Although the combination of S-1 with carboplatin is a first-line chemotherapy regimen for advanced non-small cell lung cancer (NSCLC), the efficacy and safety of the regimen in the elderly remain unknown. METHODS: The patient inclusion criteria were previously untreated advanced NSCLC, wild-type epidermal growth factor receptor, aged 70 years or more, and a performance status (PS) of 0-2...
October 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29189761/heterogenization-of-ketone-catalyst-for-epoxidation-by-low-pressure-plasma-fluorination-of-silica-gel-supports
#18
Lucia D'Accolti, Nicoletta De Vietro, Fiorenza Fanelli, Caterina Fusco, Angelo Nacci, Francesco Fracassi
Low pressure plasma was used for preparing heterogeneous organocatalysts 2-(A)-(C) suitable for dioxirane-mediated epoxidations. Heterogenization was accomplished by adsorption of the methyl perfluoroheptyl ketone (2) on fluorinated supports (A)-(C) deriving from the treatment of commercial C₈-silica gel in low pressure plasma fed with fluorocarbons. Catalyst 2-(C) proved to be the most efficient one, promoting epoxidation of an array of alkenes, including unsaturated fatty esters like methyl oleate (10) and the triglyceride soybean oil (11), with the cheap potassium peroxymonosulfate KHSO₅ (caroate) as a green oxidant...
November 30, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29187799/appropriateness-of-digoxin-measurement-in-hospitalized-patients
#19
Seyma Oncu, Ayse Gelal, Ozgur Aslan, Reyhan S Ucku
Introduction: Measurement of serum digoxin concentrations before steady-state is reached results in a falsely low concentration, and may affect treatment safety. We evaluated the proportion of serum digoxin measurements performed before steady-state is reached and the reasons for inappropriate sampling in hospitalized patients. Materials and methods: Electronic medical records of patients hospitalized between January 2011 and December 2015 treated with oral digoxin, that had more than one digoxin measurement were included...
February 15, 2018: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/29187765/effect-of-land-use-seasonality-and-hydrometeorological-conditions-on-the-k-concentration-discharge-relationship-during-different-types-of-floods-in-carpathian-foothills-catchments-poland
#20
Joanna P Siwek, Mirosław Żelazny, Janusz Siwek, Wojciech Szymański
The purpose of the study was to determine the role of land use, seasonality, and hydrometeorological conditions on the relationship between stream water potassium (K+) concentration and discharge during different types of floods-short- and long-duration rainfall floods as well as snowmelt floods on frozen and thawed soils. The research was conducted in small catchments (agricultural, woodland, mixed-use) in the Carpathian Foothills (Poland). In the woodland catchment, lower K+ concentrations were noted for each given specific runoff value for summer rainfall floods versus snowmelt floods (seasonal effect)...
2017: Water, Air, and Soil Pollution
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