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https://www.readbyqxmd.com/read/28549873/comparison-of-the-recovery-rate-of-otomycosis-using-betadine-and-clotrimazole-topical-treatment
#1
Mohammad Reza Mofatteh, Zahra Naseripour Yazdi, Masoud Yousefi, Mohammad Hasan Namaei
INTRODUCTION: Otomycosis is a common diseases that can be associated with many complications including involvement of the inner ear and mortality in rare cases. Management of otomycosis can be challenging, and requires a close follow-up. Treatment options for otomycosis include local debridement, local and systemic antifungal agents and utilization of topical antiseptics. OBJECTIVE: This study was designed to compare the recovery rate of otomycosis using two therapeutic methods; topical betadine (Povidone-iodine) and clotrimazole...
May 6, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28537349/effects-of-topical-antiseptic-solutions-used-during-total-knee-arthroplasty-on-suture-tensile-strength
#2
Jared M Newman, Jaiben George, Jeffery T Shepherd, Alison K Klika, Carlos A Higuera, Viktor E Krebs
INTRODUCTION: Irrigating a surgical wound with an antiseptic solution is commonly performed while suturing following a total knee arthroplasty (TKA) to help prevent wound complications. The purpose of this study was to: 1) evaluate the mean load to failure of different sutures, and 2) compare the mean load to failure of the sutures after soaking in four different antiseptic solutions. MATERIALS AND METHODS: Load-to-failure tests were conducted on four sets of comparable sutures (eight sutures) from two different companies Ethicon Inc...
May 24, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28529859/treatment-of-periprosthetic-joint-infection-using-antimicrobials-dilute-povidone-iodine-lavage
#3
REVIEW
John A Ruder, Bryan D Springer
Periprosthetic joint infections (PJI) remain a challenge for the orthopaedic surgeon to treat and remain a leading cause of failure of both primary and revision total joint arthroplasty. Once a PJI develops, surgical treatment is generally indicated and includes an aggressive irrigation and debridement. One component of the irrigation and debridement involves the use of an antiseptic irrigating solution. In primary and revision TJA, dilute povidone-iodine lavage can be performed prior to wound closure. Approximately 17...
2017: J Bone Jt Infect
https://www.readbyqxmd.com/read/28529858/hydrogen-peroxide-wound-irrigation-in-orthopaedic-surgery
#4
REVIEW
Min Lu, Erik Nathan Hansen
As the burden of deep hardware infections continues to rise in orthopaedics, there is increasing interest in strategies for more effective debridement of colonized tissues and biofilm. Hydrogen peroxide has been used medically for almost a century, but its applications in orthopaedic surgery have yet to be fully determined. The basic science and clinical research on the antiseptic efficacy of hydrogen peroxide have demonstrated its efficacy against bacteria, and it has demonstrated potential synergy with other irrigation solutions such as chlorhexidine and povidone-iodine...
2017: J Bone Jt Infect
https://www.readbyqxmd.com/read/28520604/in-vitro-evaluation-of-betafoam-a-new-polyurethane-foam-dressing
#5
Jae-A Jung, Seung-Kyu Han, Seong-Ho Jeong, Eun-Sang Dhong, Kang-Gyun Park, Woo-Kyung Kim
BACKGROUND: A new polyurethane foam dressing impregnated with 3% povidone-iodine (Betafoam; Genewell, Seoul, Korea) was recently developed based on the hypothesis that its physical properties, including improved moisture-retention capacity and antimicrobial activity, are at least as good as those achieved with the current foam dressings that contain silver, but also associated with reduced cost and cytotoxicity to host cells. The purpose of this in vitro study was to evaluate the efficacy of Betafoam by comparing its physical properties, antimicrobial activity, and cytotoxicity with those of 3 silver foam dressings (Allevyn-Ag [Smith & Nephew, Hull, United Kingdom]; Mepilex-Ag [Mölnlycke Health Care, Gothenburg, Sweden]; and PolyMem-Ag [Ferris MFG Corp, Burr Ridge, Illinois]) used worldwide...
June 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28516852/effects-of-olanexidine-gluconate-on-preoperative-skin-preparation-an-experimental-study-in-cynomolgus-monkeys
#6
Hikaru Nakata, Yoshie Tsubotani, Takuya Nii, Akifumi Hagi, Yasuhide Inoue, Tadashi Imamura
PURPOSE: To determine the bactericidal efficacy of a new topical antiseptic for preoperative skin preparation, olanexidine gluconate (development code: OPB-2045G), against transient or resident bacterial flora on the skin of cynomolgus monkeys. METHODOLOGY: After measuring baseline bacterial counts on test sites marked on the abdomens, we applied olanexidine, chlorhexidine or povidone-iodine. After 10 min (fast-acting effect) and 6 h (long-lasting effect), bacterial counts were measured again and log10 reductions were calculated...
May 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28513067/interventions-for-cutaneous-molluscum-contagiosum
#7
REVIEW
Johannes C van der Wouden, Renske van der Sande, Emma J Kruithof, Annet Sollie, Lisette Wa van Suijlekom-Smit, Sander Koning
BACKGROUND: Molluscum contagiosum is a common skin infection that is caused by a pox virus and occurs mainly in children. The infection usually resolves within months in people without immune deficiency, but treatment may be preferred for social and cosmetic reasons or to avoid spreading the infection. A clear evidence base supporting the various treatments is lacking.This is an update of a Cochrane Review first published in 2006, and updated previously in 2009. OBJECTIVES: To assess the effects of specific treatments and management strategies, including waiting for natural resolution, for cutaneous, non-genital molluscum contagiosum in people without immune deficiency...
May 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28505031/povidone-iodine-solutions-inhibit-cell-migration-and-survival-of-osteoblasts-fibroblasts-and-myoblasts
#8
James X Liu, Jordan A Werner, John A Buza, Thorsten Kirsch, Joseph D Zuckerman, Mandeep S Virk
STUDY DESIGN: In vitro laboratory study. OBJECTIVE: The purpose of this study was to identify the effect of dilute povidone-iodine (PVI) solutions on human osteoblast, fibroblast and myoblast cells in vitro. SUMMARY OF BACKGROUND DATA: Dilute PVI wound lavage has been used successfully in spine and joint arthroplasty procedures to prevent post-operative surgical site infection, but their biologic effect on host cells is largely unknown. METHODS: Human primary osteoblasts, fibroblasts, and myoblasts were expanded in cell culture and subjected to various concentrations of PVI (0%, 0...
April 12, 2017: Spine
https://www.readbyqxmd.com/read/28492198/comparison-of-efficacy-of-three-chemotherapeutic-agents-on-streptococcus-mutans-count-in-plaque-and-saliva-a-randomized-controlled-triple-blind-study
#9
Ajay Narayan, Savitha Satyaprasad, S Anandraj, S R Ananda, P Ananth Kamath, S Nandan
BACKGROUND: There is a need for exploration of the role of chemotherapeutic agents and its role in the prevention of early childhood caries (ECC) and its recurrence. AIM: The aim of this study was two-fold: (1) To compare the antimicrobial efficacy of three commonly used chemotherapeutic agents in the prevention of ECC in comparison with a control and (2) To ascertain the role of chemotherapeutic agents in the prevention of ECC. MATERIALS AND METHODS: Sixty children with ECC in the age group 3-6 years were randomly allocated into four groups...
April 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28489234/the-treatment-of-otorrhea-in-children-with-cleft-palate-an-institutional-review
#10
Stephen Nogan, Katie Phillips, Jonathan Grischkan
We conducted a retrospective observational chart review to characterize otorrhea in patients with cleft palate (CP) after tympanostomy tube placement in terms of the bacteria profile, treatment effectiveness, and overall disease burden. A total of 157 patients over 6 years were reviewed. Fifty of the 157 patients (31.8%) experienced postoperative otorrhea. Of the 50 patients with otorrhea, all received topical antibiotics, 30 received oral antibiotics, and 12 received povidone-iodine irrigations. The average duration of otorrhea was 5...
April 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28480773/new-gentle-wing-high-shear-granulator-impact-of-processing-variables-on-granules-and-tablets-characteristics-of-high-drug-loading-formulation-using-design-of-experiment-approach
#11
Mohamed H Fayed, Sayed I Abdel-Rahman, Fars K Alanazi, Mahrous O Ahmed, Hesham M Tawfeek, Ramadan I Al-Shdefat
The aim of this work was to study the application of design of experiment (DoE) approach in defining design space for granulation and tableting processes using a novel gentle-wing high shear granulator. According to quality-by-design (QbD) prospective, critical attributes of granules and tablets should be ensured by manufacturing process design. A face centered central composite design has been employed in order to investigate the effect of water amount (X1), impeller speed (X2), wet massing time (X3) and water addition rate (X4) as independent process variables on granules and tablets characteristics...
May 8, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28476310/intra-operative-techniques-to-reduce-the-risk-of-capsular-contracture-in-patients-undergoing-aesthetic-breast-augmentation-a-review
#12
REVIEW
J D Horsnell, A E Searle, P A Harris
BACKGROUND: Capsular contracture is a significant complication following aesthetic breast augmentation. Efforts to reduce this incidence have focused on the surgical approach, implant selection and IV antibiotics. Intra-operative methods to reduce the risk have had less investigation. This review focuses on these interventions and will document evidence to support pocket irrigation, nipple shields, drains and the use of an implant insertion funnel. METHODS: A comprehensive review of Pubmed, Scopus and Embase was performed to identify relevant papers published since 2000...
May 2, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28455575/-prophylaxis-of-infectious-complications-following-prostate-biopsy
#13
REVIEW
A Pilatz, G Lüdecke, F Wagenlehner
Different strategies have been developed to reduce infectious complications following prostate biopsy. Various technical aspects like number of biopsies, needle size, route of biopsy, periprostatic nerve blockade, rectal preparation by enema, or disinfection with povidone-iodine have to be discussed. Regarding antibiotic therapy, choosing the optimal antibiotic, the duration of prophylaxis, combination therapy, and rectal swab-based antimicrobial therapy are of major interest. The current review gives answers to the different aspects...
April 28, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28448203/systematic-review-and-meta-analysis-of-randomized-controlled-trials-evaluating-prophylactic-intra-operative-wound-irrigation-for-the-prevention-of-surgical-site-infections
#14
Stijn W de Jonge, Quirine J J Boldingh, Joseph S Solomkin, Benedetta Allegranzi, Matthias Egger, E Patchen Dellinger, Marja A Boermeester
BACKGROUND: Surgical site infections (SSIs) are one of the most common hospital-acquired infections. To reduce SSIs, prophylactic intra-operative wound irrigation (pIOWI) has been advocated, although the results to date are equivocal. To develop recommendations for the new World Health Organization (WHO) SSI prevention guidelines, a systematic literature review and a meta-analysis were conducted on the effectiveness of pIOWI using different agents as a means of reducing SSI. METHODS: The PUBMED, Embase, CENTRAL, CINAHL, and WHO databases were searched...
May 2017: Surgical Infections
https://www.readbyqxmd.com/read/28430323/povidone-iodine-3-minute-exposure-time-is-viable-in-preparation-for-cataract-surgery
#15
Chu Luan Nguyen, Lawrence J Oh, Eugene Wong, Ian C Francis
PURPOSE: Povidone-iodine (PI) is widely used to reduce the preoperative conjunctival bacterial load. This study aimed to evaluate the employment of PI 10% in an attempt to sterilize the ocular surface prior to cataract surgery, and to show that PI could be left in contact for 3 minutes. The viability of this exposure time in clinical practice, associated adverse events, and visual outcomes were documented. METHODS: In this prospective cohort study, phacoemulsification cataract surgery was performed in 604 patients by a single surgeon...
April 7, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28428640/transforming-growth-factor-%C3%AE-plays-an-important-role-in-enhancing-wound-healing-by-topical-application-of-povidone-iodine
#16
Li Wang, Wenhan Qin, Yaying Zhou, Bin Chen, Xiaoqing Zhao, Hailin Zhao, Emma Mi, Ella Mi, Qingmei Wang, Jiaolin Ning
Povidone-iodine (PVI) is principally used as an antimicrobial agent. It has been found that 0.5% PVI can attenuate congestion, edema and pain induced by pressure sores. Thus this study aimed to assess the effects of 0.5% PVI on acute skin wounds. Four full-thickness excisional wounds were generated on the dorsal skin of male Sprague-Dawley rats with a 10-mm sterile punch. Two wounds were left untreated and the other two were dressed with gauze with 0.5% PVI for 1 hour per day for the first 5 days after injury...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28410725/optimizing-the-antisepsis-protocol-effectiveness-of-3-povidone-iodine-1-0-applications-versus-a-single-application-of%C3%A2-povidone-iodine-5-0
#17
Megan R Silas, Richard M Schroeder, Richard B Thomson, William G Myers
PURPOSE: To determine the minimum effective concentration of povidone-iodine that reduces the bacterial load by 3-log10, the U.S. Food and Drug Administration requirement for antiseptic agents, and to study alternative dosing schedules of povidone-iodine to optimize its bactericidal effect. SETTING: Microbiology Laboratory, Evanston Hospital, Evanston, Illinois, USA. DESIGN: Experimental study. METHODS: A standard 0...
March 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28405039/disinfection-of-laryngoscopes-a-survey-of-practice
#18
Vaishali Prabhakar Chaskar, Nandini Malay Dave, Raylene Dias, Priyanka Karnik
BACKGROUND AND AIMS: The laryngoscope is a common piece of equipment used by anaesthesiologists. It has been identified as a potential source of cross infection. Although guidelines exist regarding appropriate disinfection practices, recent reviews suggest ineffectiveness of current methods of disinfection and poor compliance with the established protocols. We conducted a questionnaire-based survey to study the current disinfection practices being followed by a cross section of anaesthesiologists...
March 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28401738/clinical-comparison-of-the-efficacy-of-three-different-bowel-preparation-methods-on-the-infectious-complications-following-transrectal-ultrasonography-guided-prostate-biopsy-in-nursing-practice
#19
Xin-Hong Zhang, Yong Jia, Wei-Hua Guo, Yu-Rong Ma, Jing Yang, Yu Zhang, Si-Chuan Hou, Chang-Cun Zhang
AIMS AND OBJECTIVES: To assess the effects of three different bowel preparation methods on the incidence of infectious complications in patients who underwent transrectal ultrasonography (TRUS) guided prostate biopsy. BACKGROUND: The standard bowel preparation protocol for prostate biopsy has not been established. DESIGN: A retrospective study in a single center. METHODS: From January 2013 to December 2015, the clinical records of 1130 patients who underwent prostate biopsy were respectively reviewed...
April 12, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28400958/in-vitro-evaluation-of-the-susceptibility-of-acinetobacter-baumannii-isolates-to-antiseptics-and-disinfectants-comparison-between-clinical-and-environmental-isolates
#20
Sanae Lanjri, Jean Uwingabiye, Mohammed Frikh, Lina Abdellatifi, Jalal Kasouati, Adil Maleb, Abdelouahed Bait, Abdelhay Lemnouer, Mostafa Elouennass
BACKGROUND: This study aims to assess the susceptibility of Acinetobacter baumannii isolates to the antiseptics and disinfectants commonly used, and to the non-approved product. METHODS: This is a prospective study carried out from February to August 2015, in the Bacteriology department of Mohammed V Military Teaching hospital of Rabat on A.baumannii isolates collected from colonized and/or infected patients and environmental samples. The antiseptics and disinfectants susceptibility testing was assessed using the micromethod validated in our department...
2017: Antimicrobial Resistance and Infection Control
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