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Craig Winkler, Joel Dennison, Adam Wooldridge, Eneko Larumbe, Cyrus Caroom, Mark Jenkins, George Brindley
Periprosthetic joint infections (PJI) are uncommon but not rare and have significant morbidity and financial implications. Local antibiotics have been used successfully in other areas of orthopedics to reduce postoperative infections, but this method has not been proven in total joint arthroplasty (TJA). Beginning January 1, 2014, our primary investigators began using surgical site lavage with providone-iodine solution and administering 2 g of vancomcyin powder in the surgical wound prior to capsule closure for all primary and revision total hip and knee arthroplasties...
March 2018: Journal of Clinical Orthopaedics and Trauma
Harun Djozic, Haris Pandza, Sefik Hasukic, Samir Custovic, Berina Pandza, Amina Krupalija, Edin Beciragic
BACKGROUND: The risk of wound infection after elective inguinal hernia repair depends on several factors. One of the most important factors is the preoperative skin preparation. The use of antisepsis is performed to reduce the risk of surgical site infections (SSIs) and to remove causing organisms. This work compares two different agent forms for preoperative skin preparation to prevent SSIs. OBJECTIVES: The objective of the study is comparing the effects of two different agents used for preoperative skin preparation and prevention of SSIs...
April 2016: Medical Archives
Steven A Neihaus, Terri L Hathcock, Dawn M Boothe, Robert L Goring
Antiseptic flushing of the canine prepuce and its exclusion from the surgical field are recommended before abdominal surgery to reduce the risk of bacterial contamination. The authors cultured the preputial cavity of 60 dogs prior to and following flushing with 0.05% chlorhexidine diacetate, 1% povidone-iodine, or 0.9% saline control. Bacterial growth was evaluated using a semiquantitative method, and bacterial organisms were subsequently identified. There were no significant differences between povidone-iodine and the saline control in any of the variables assessed...
November 2011: Journal of the American Animal Hospital Association
A Gupta, V Lakshmi, G K Jain, R Raghubir
OBJECTIVE: To investigate the healing efficacy of Pentaceraster regulus (starfish) aqueous-methanol extract on cutaneous wounds in guinea pigs. METHOD: Freshly collected starfish were washed with distilled water and soaked in methanol for transportation. After filtering, soaking and concentration, the extract was fractionated into chloroform soluble (5g), 50% aqueous-methanol soluble (20g) and insoluble fractions (25g). Primary screening demonstrated moderate wound-healing activity in male Swiss-strain guinea pigs, so further fractionation into chloroform, 50% aqueous-methanol and insoluble fractions was undertaken...
October 2008: Journal of Wound Care
Dena S Hammoudi, Mohamed Abdolell, David T Wong
BACKGROUND: The objective of this study was to document prophylactic methods used for cataract surgery in Canada. METHODS: The Web-based link to a password-protected, anonymous, online survey was e-mailed or mailed, between November 2004 and January 2005, to 800 ophthalmologists practicing in Canada. RESULTS: Of the 239 respondents (30% response rate), 216 performed cataract surgery. Phacoemulsification was preferred by 99%. Topical antibiotics, of which moxifloxacin was the most common (32%), were used preoperatively by 78%...
October 2007: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Hitoshi Matsuoka, Yuki Mizushima, Masako Kawano, Naoko Tachibana, Yoshiko Sawada, Sachiko Kato, Hiromi Nagakura, Miyuki Tanaka, Keiko Suzuki, Kuribayashi Tadanobu
The stomatitis accompanying chemotherapy reduces a patient's QOL. Many reports have suggested that some kinds of gargling agents for oral mucositis shorten the duration and severity of symptoms. This study tested the prevention and efficacy against stomatitis of a herbal medicine (Syousaikotou) as a gargling agent for patients receiving chemotherapy. Compared to gargling with providone-iodine and amphotericin B, the Syousaikotou gargle showed a significantly decreased incidence of stomatitis, and a painkilling effect...
November 2004: Gan to Kagaku Ryoho. Cancer & Chemotherapy
T Stricker, F Navratil, F H Sennhauser
OBJECTIVE: To evaluate the clinical features and outcome in girls with a vaginal foreign body. METHODS: Retrospective review of medical records of 35 girls with a vaginal foreign body seen in an outpatient clinic for paediatric and adolescent gynaecology between 1980 and 2000. RESULTS: The ages ranged from 2.6 to 9.2 years. The most common symptom was blood-stained vaginal discharge/vaginal bleeding (49%). Duration of symptoms varied from 1 day to 2 years...
April 2004: Journal of Paediatrics and Child Health
No abstract text is available yet for this article.
February 1965: Practitioner
No abstract text is available yet for this article.
December 1961: Current Therapeutic Research, Clinical and Experimental
Lubica Kovacikova, Pavol Kunovsky, Miroslav Lakomy, Peter Skrak, Zelmira Misikova, Jaroslav Siman, Ludmila Kostalova, Eva Tomeckova
OBJECTIVE: The aim of this prospective study was to examine whether providone-iodine used for sternal wound protection in infants with delayed sternal closure (DSC) influences the thyroid function. PATIENTS AND METHODS: Thyroid hormones (see bellow) and thyroxine binding globulin (TBG) were estimated by radioimmunoassay and ioduria by mass spectrometry in 20 infants in whom cutaneous povidone-iodine was continuously applied on the skin for 1-7 days before DSC after open heart surgery...
March 2003: Endocrine Regulations
E G Papanikolaou, G Tsanadis, N Dalkalitsis, D Lolis
Bacterial vaginosis (BV) is a polymicrobial infection of the vagina and should not be considered an exclusively sexually transmitted disease. We describe the case of a 17-year-old female virgin adolescent with recurrent malodorous vaginal discharge for 6 months. Before referral to us she had been treated unsuccessfully with conservative treatment options. Our investigation revealed Gardnerella vaginalis as the responsible factor for the vaginal infection. Because metronidazole treatment had failed as monotherapy, a new method was applied...
December 2002: Infection
E Martín Jiménez, M J Menesas Escribano, D Castejón Martin, C Gil Martínez, P Pérez Doblado, B P Rodríguez
Unified care when treating an episiotomy is essential to avoid complications which develop during puerperium. An analysis was carried out by means of a comparative clinical study of two groups of primiparous women, the evolution of their episiotomy in terms of the application of 0.4% providone-iodine" in eight qualitative variables analyzed independently. Due to its greater influence on the evolution of an episiotomy, this study evaluated in more depth one of these variables which defines its quality: dehiscence...
November 2001: Revista de Enfermería
A M Bhagwat, S Save, S Burli, S G Karki
Feracrylum, a water-soluble polymer of polyacrylic acid is known for its hemostatic property. Present work is an effort to evaluate its minimum inhibitory concentration (MIC) and compare it with the MIC of povidone-iodine. Ten different species of pathogenic microorganisms were selected, strains of which were obtained from Haffkine Institute. The organisms were maintained under appropriate culture media. The MIC of Freracrylum was determined by using tube culture method where its activity was compared against a standard antimicrobial agent providone-iodine...
October 2001: Indian Journal of Pathology & Microbiology
T Das, S Sharma, J Singh, V Rao, K V Chalam
BACKGROUND AND OBJECTIVE: Wide-field vitrectomy contact lenses are currently sterilized with ethylene oxide gas, and other lenses with autoclaving. To maintain a large inventory or possibly run the risk of loss of lens quality with repeated autoclaving, glutaraldehyde 2% and povidone iodine 5% solution were evaluated as possible sterilizing agents. MATERIALS AND METHODS: Ethylene oxide presterilized lenses were contaminated with known concentrations (10(5) organisms/mL) of bacteria (S...
July 2001: Ophthalmic Surgery and Lasers
J Arena Ansotegui, J I Emparanza Knörr
The use of iodine-containing antiseptics is still common in obstetrics and neonatology. Topical iodine given both to the mother before delivery and to the neonate causes iodine overload. The absorption of maternal iodine through the skin is so fast that iodine in the blood of the umbilical cord increases by 50% a few minutes before delivery. Iodine overload also occurs in the mother. Urinary and breast-milk iodine are increased more than 10-fold in the days after delivery if providone-iodine is used in episiotomy...
July 2000: Anales Españoles de Pediatría
H Benghuzzi
This study will attempt to determine the amount of circulating drug, when provided at sustained levels over an extended period of time, which provides efficacy and reduces the toxic side effects seen with the use of AZT in vivo. Two ceramic delivery systems were selected for this investigation namely tricalcium-phosphate (TCP) and hydroxyapatite (HA) ceramic implants. Three different dosages were selected (60, 90, 180 mg AZT). A total of 105 rats were used in this study and they were further divided into seven equal groups (n = 15 per group, 250-300 gm BW)...
2000: Biomedical Sciences Instrumentation
M E Molina, D E Nonweiller, J A Evans, J C Delee
PURPOSE: A study was undertaken to determine the incidence of positive cultures resulting from an anterior cruciate ligament (ACL) specimen dropped on the operating room floor and the efficacy of sterilizing the specimen by soaking in 1 of 3 antimicrobial solutions: an antibiotic solution of neomycin and polymyxin B, 10% providone-iodine solution, and standard chlorhexidine gluconate solution. TYPE OF STUDY: Randomized trial. MATERIALS AND METHODS: Fifty ACL specimens removed from patients undergoing total knee arthroplasty were used as the test group...
May 2000: Arthroscopy: the Journal of Arthroscopic & related Surgery
D Souvenir, D E Anderson, S Palpant, H Mroch, S Askin, J Anderson, J Claridge, J Eiland, C Malone, M W Garrison, P Watson, D M Campbell
A blood culture cohort study investigating issues related to isolation of coagulase-negative staphylococci (CoNS) and other skin microflora is reported. Data were collected over 12 weeks to determine the incidence of significant CoNS bacteremia versus that of pseudobacteremia (contaminants) and to evaluate drug therapy in patients with cultures positive for CoNS. In addition, the effectiveness of 0.2% chlorine peroxide as a bactericidal disinfectant was compared to that of 10% providone iodine. A total of 3,276 cultures of blood from 1,433 patients were evaluated in the study...
July 1998: Journal of Clinical Microbiology
A Desrochers, G St-Jean, D E Anderson, D P Rogers, M M Chengappa
One hundred seventeen cattle that had undergone surgery were assigned randomly to two preoperative skin preparation protocols. Group 1 (60 animals) skin preparation was with povidoneiodine soap and isopropyl alcohol, whereas group 2 (57 animals) had skin preparation with chlorhexidine gluconate and isopropyl alcohol. Quantitative microbial culture plates were used to estimate the number of colony forming units (CFUs) before skin preparation (prescrub), after skin preparation (postscrub), after surgery (postoperative), and in room air (environment)...
July 1996: Veterinary Surgery: VS
S Asano, H Murayama, A Ishida, Y Nakagawa, M Ito, Y Sudo
A 78-year-old man underwent total aortic arch replacement for ruptured aortic arch aneurysm. Two weeks after the surgery, high fever and leucocytosis developed. He was placed on a regimen of antibiotics. However, mediastinitis eventually ensued five weeks later with the pus draining from the sternotomy wound. The culture revealed a Methicillin resistant staphylococcus aureus. The infected tissue was debrided from the mediastinal cavity 40 days postoperatively. The cavity was kept open and was intermittently irrigated with 2% Providone-iodine for three days...
June 1996: [Zasshi] [Journal]
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