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https://www.readbyqxmd.com/read/28448359/rare-allergic-reaction-to-topical-chlorhexidine-gluconate
#1
Diane S Aschenbrenner
No abstract text is available yet for this article.
May 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28448318/two-state-collaborative-study-of-a-multifaceted-intervention-to-decrease-ventilator-associated-events
#2
Nishi Rawat, Ting Yang, Kisha J Ali, Mary Catanzaro, Mariah D Cohen, Donna O Farley, Lisa H Lubomski, David A Thompson, Bradford D Winters, Sara E Cosgrove, Michael Klompas, Kathleen A Speck, Sean M Berenholtz
OBJECTIVES: Ventilator-associated events are associated with increased mortality, prolonged mechanical ventilation, and longer ICU stay. Given strong national interest in improving ventilated patient care, the National Institute of Health and Agency for Healthcare Research and Quality funded a two-state collaborative to reduce ventilator-associated events. We describe the collaborative's impact on ventilator-associated event rates in 56 ICUs. DESIGN: Longitudinal quasi-experimental study...
April 26, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28447965/perspectives-of-using-of-aseptic-drains-for-abdominal-drainage
#3
Merab Kiladze, Paata Tutberidze, Maka Gogoladze, David Tugushi, Ramaz Katsarava, Tsismari Gatenadze
AIM: Aim of the study was to evaluate the effectiveness of using different types of drain tubes to prevent and reduce the drain-associated infection rate of abdominal drainage procedures. MATERIALS AND METHODS: 80 cases of used so called "standard", "coladerm" and "chlorhexidine" drain tubes for abdominal drainage were analysed. "Standard" drain tubes were used 35 times and "coladerm" and "chlorhexidine" tubes - 20 and 25 times respectively. There were adopted in different elective and emergency so called "clean", "potentially contaminated" and "contaminated" abdominal surgical procedures...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28446851/an-invitro-evaluation-of-the-accuracy-of-two-electronic-apex-locators-to-determine-working-length-in-the-presence-of-various-irrigants
#4
Ashwini B Prasad, Srivastava Harshit, Srivastava Arora Aastha, Raisingani Deepak
BACKGROUND: Cleaning and shaping of root canal system requires various irrigating solutions. The question is whether the presence of irrigation solution alters working length determination using apex locators. The purpose of this study was to compare the accuracy of Root ZX and i-Root apex locator for determining working length in the presence of different irrigating solution. MATERIALS AND METHOD: Eighty extracted single rooted human teeth were used. The teeth were sectioned at Cemento Enamel Junction (CEJ) and actual canal length determined...
September 2016: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28446176/health-care-providers-perspectives-regarding-the-use-of-chlorhexidine-gel-for-cord-care-in-neonates-in-rural-kenya-implications-for-scale-up
#5
Angela Muriuki, Francis Obare, Bill Ayieko, Dennis Matanda, Kenneth Sisimwo, Brian Mdawida
BACKGROUND: This paper explores the perspectives of health care providers regarding the use of 7.1% Chlorhexidine Digluconate (CHX) gel that releases 4% chlorhexidine for newborn umbilical cord care under a managed access program (MAP) implemented in Bungoma County of Kenya. Understanding the perspectives of providers regarding CHX is important since they play a key role in the health system and the fact that their views could be influenced by prior beliefs and inconsistent practices regarding umbilical cord care...
April 26, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28443835/effect-of-boric-acid-versus-conventional-irrigation-solutions-on-the-bond-strength-between-fiber-post-and-root-dentin
#6
Ahmet Kursad Culhaoglu, Erdal Özcan, Mehmet Ali Kilicarslan, Emre Seker
PURPOSE: To compare the effect of boric acid solutions of different percentages to conventional irrigation solutions on the adhesive bond strength between fiber posts and radicular dentin surface with different cement types. MATERIALS AND METHODS: One hundred fifteen extracted human incisors were endodontically instrumented to a length of 14-15 mm, and 12-mm post spaces were prepared with specific drills. Cylindrical fiber posts (Panavia Post) were luted with two different composite cements (Panavia F 2...
April 25, 2017: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/28443834/influence-of-different-pretreatments-on-the-microtensile-bond-strength-to-eroded-dentin
#7
Shengjile Deari, Florian J Wegehaupt, Tobias T Tauböck, Thomas Attin
PURPOSE: To evaluate the influence of different pretreatments on the microtensile bond strength (μTBS) of an etchand- rinse adhesive to eroded dentin. MATERIALS AND METHODS: Thirty-six human teeth were ground down to their dentin layer and randomly divided into six groups (G1-G6; n = 6), G1 being the control group. Only in the test groups (G2-G6) were samples subjected to erosion using citric acid (pH 2.6) 10 x 2 min per day for five days. Between the erosive attacks, samples were stored in artificial saliva...
April 25, 2017: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/28438928/the-impact-of-healthcare-exposure-on-genotypic-antiseptic-tolerance-among-pediatric-staphylococcus-aureus-infections
#8
J Chase McNeil, Kristina G Hultén, Edward O Mason, Sheldon L Kaplan
Background: Staphylococcus aureus possessing either the smr or qacA/B genes are associated with decreased susceptibility to chlorhexidine gluconate (CHG) and other antiseptics. Previous studies of antiseptic tolerant staphylococci have largely focused on high-risk populations and the exact role of healthcare exposure on acquisition of these organisms is unclear. We sought to describe the risk factors and features of infection caused by antiseptic tolerant S. aureus in a general pediatric population.Methods: Isolates were selected from an ongoing S...
April 24, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28435376/comparative-evaluation-of-antimicrobial-efficacy-of-an-alternative-natural-agent-for-disinfection-of-toothbrushes
#9
R Vignesh, C Vishnu Rekha, Parisa Norouzi Baghkomeh, Sankar Annamalai, Ditto Sharmin
OBJECTIVE: The aim of this study was to assess the antimicrobial potency of aqueous extract of Psidium guajava leaves in two different concentrations as a toothbrush disinfectant against three oral bacterial species. MATERIALS AND METHODS: Aqueous extracts of P. guajava leaves were prepared at 20% and 30% concentrations and 0.2% chlorhexidine was used as control. The toothbrushes were equally divided into 9 groups with 10 toothbrushes per disinfectant, which were contaminated with Streptococcus mutans, Lactobacillus acidophilus, and Enterococcus faecalis...
January 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28434696/complete-eradication-of-biofilm-from-orthopedic-materials
#10
Jeffrey T Leary, Matthew M Werger, William H Broach, Lindsey N Shaw, Brandon G Santoni, Thomas L Bernasek, Steven T Lyons
BACKGROUND: Interest exists in finding alternatives to current management strategies in periprosthetic joint infections, which typically include a 2-stage revision with placement of an antibiotic spacer and delayed placement of a new implant. We studied the efficacy of autoclaving, ultrasonication, and mechanical scrubbing for sterilization and biofilm eradication on infected cobalt-chrome discs. METHODS: Strains of Staphylococcus aureus MRSA252 or Staphylococcus epidermidis RP62A were grown on the discs...
March 29, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28431846/implementation-of-daily-chlorhexidine-bathing-to-reduce-colonization-by-multidrug-resistant-organisms-in-a-critical-care-unit
#11
Jackson S Musuuza, Ajay K Sethi, Tonya J Roberts, Nasia Safdar
BACKGROUND: Colonized patients are a reservoir for transmission of multidrug-resistant organisms (MDROs). Not many studies have examined the effectiveness of daily chlorhexidine gluconate (CHG) bathing under routine care conditions. We present a descriptive analysis of the trends of MDRO colonization following implementation of daily CHG bathing under routine clinical conditions in an intensive care unit (ICU). METHODS: From May 2010-January 2011, we screened patients admitted to a 24-bed ICU for and methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and fluoroquinolone-resistant gram-negative bacilli (FQRGNB)...
April 18, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28430753/impact-of-chlorhexidine-cord-cleansing-on-mortality-omphalitis-and-cord-separation-time-among-facility-born-babies-in-nepal-and-bangladesh
#12
Luke C Mullany, Shams El Arifeen, Subarna K Khatry, Joanne Katz, Rashed Shah, Abdullah H Baqui, James M Tielsch
Guidance is needed regarding potential extension of the WHO recommendation for cord cleansing with chlorhexidine to babies born in facilities. Among 3,223 facility-born babies from Nepal and Bangladesh, mortality was approximately halved among those allocated to the intervention clusters (10.5/1000 vs. 19.4/1000, RR=0.54; 95% CI: 0.30 - 0.97). In high-mortality settings, a single policy for home and facility births is warranted.
April 19, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28430730/comment-on-chlorhexidine-keratitis
#13
Kenneth D Steinsapir, Julie Woodward
No abstract text is available yet for this article.
April 19, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28428592/antibiotic-prophylaxis-for-infective-endocarditis-some-rarely-addressed-issues
#14
R Pippi
Although quite consistent indications on antibiotic prophylaxis for infective endocarditis (IE) have been reported internationally, several common dental practice issues are still not clear: which dental procedures require antibiotic prophylaxis? In the case of multiple procedures can the same antibiotic be used? How can dentists identify high-risk conditions for IE? Do dentists verify patient antibiotic intake? What are the requirements of antibiotic prophylaxis in cases of coexistence of diseases which involve host defence impairment? What are the modalities of second choice drug administration? And finally, are chlorhexidine mouthwashes before dental procedures combined with antibiotics useful or not? Uncertainty also persists as far as the real need for prophylaxis is concerned and although several sources have suggested that a wide prospective randomised controlled study may be the definitive solution, problems exist in performing such a study...
April 21, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28425718/testing-high-concentrations-of-membrane-active-antibiotic-chlorhexidine-via-computational-titration-and-calorimetry
#15
Brad Van Oosten, Drew Marquardt, Thad A Harroun
Coarse grained strategies for membrane simulations are designed to increase the time and length scales of molecular dynamics simulations. For membrane active antibiotics, the concentration dependence of their action presents a tremendous challenge in simulation scale. In this study we examine the effects of concentration for the popular membrane active antibacterial drug chlorhexidine. It presents an interesting biophysical modelling test, where from experimental experience we know that model membranes of DMPC can absorb very high quantities of the drug without disruption...
April 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28422796/waterless-hand-rub-versus-traditional-hand-scrub-methods-for-preventing-the-surgical-site-infection-in-orthopaedic-surgery
#16
Kentaro Iwakiri, Akio Kobayashi, Masahiko Seki, Yoshiyuki Ando, Tadao Tsujio, Masatoshi Hoshino, Hiroaki Nakamura
STUDY DESIGN: A retrospective cohort study with prospectively collected data OBJECTIVE.: The aim of this study was to compare SSI incidences, the cost of hand hygiene agents, and hand hygiene time between the traditional hand scrub and the waterless hand rub protocols before orthopaedic surgery. SUMMARY OF BACKGROUND DATA: Surgical-site-infections (SSI) prolong hospitalization and are a leading nosocomial cause of morbidity as well as a source of excess cost. Recently, a waterless hand rub protocol comprising alcohol based chlorhexidine gluconate for use before surgery was developed, but no studies have yet examined its utility in orthopaedic surgery...
April 18, 2017: Spine
https://www.readbyqxmd.com/read/28420834/improving-the-efficacy-of-chlorhexidine-releasing-elastomerics-using-a-layerby-layer-coating-technique
#17
Hyun-Sun Jeon, Eun-Ha Jung, Si-Mook Kang, Eun-Song Lee, Jeong-Woo Lee, Baek-Il Kim
The aims of this study were to identify the optimal concentration of coated orthodontic elastomerics using a layer-by-layer technique that can release chlorhexidine (CHX) as an antimicrobial material, and to measure the physical properties and antimicrobial effects of the coated elastomerics. Ethyl cellulose (EC) was used as the polymer, and five study groups with various combinations of solvents (i.e., ethanol and dichloromethane [DCM]) were included. The coated elastomerics were evaluated with a spectrophotometer to confirm the release of CHX, and their surfaces were observed by SEM...
April 18, 2017: Dental Materials Journal
https://www.readbyqxmd.com/read/28420291/a-study-of-long-term-stability-and-antimicrobial-activity-of-chlorhexidine-polyhexamethylene-biguanide-and-silver-nanoparticle-incorporated-in-sericin-based-wound-dressing
#18
Sumate Ampawong, Pornanong Aramwit
In this study, three kinds of antiseptics which were 0.05% chlorhexidine, 0.2% polyhexamethylene biguanide (PHMB), or 200 ppm silver nanoparticle was introduced to incorporate in the sericin-based scaffold to produce the antimicrobial dressing for the treatment of infected chronic wound. The effects of antiseptic incorporation on the stability, release of sericin, and short-term and long-term (6 months) antimicrobial activity of the sericin dressing against gram-negative and gram-positive bacteria were investigated...
April 19, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/28417918/high-prevalence-of-blandm-1-blavim-qace-and-qace%C3%AE-1-genes-and-their-association-with-decreased-susceptibility-to-antibiotics-and-common-hospital-biocides-in-clinical-isolates-of-acinetobacter-baumannii
#19
Fatma Alzahraa M Gomaa, Zeinab H Helal, Mazhar I Khan
The objective of this study was to evaluate the susceptibility of metallo-β-lactamase (MBL)-producing Acinetobacter baumannii (A. baumannii) clinical isolates to biocides. We also determined the prevalence and correlation of efflux pump genes, class 1 integron and MBL encoding genes. In addition, blaVIM, blaNDM-1, qacE and qacEΔ1 nucleotide sequence analysis was performed and compared to sequences retrieved from GenBank at the National Center for Biotechnology Information database. A. baumannii had a resistance rate to carbapenem of 71...
April 12, 2017: Microorganisms
https://www.readbyqxmd.com/read/28415444/formulation-of-thermoreversible-gel-of-cranberry-juice-concentrate-evaluation-biocompatibility-studies-and-its-antimicrobial-activity-against-periodontal-pathogens
#20
Rajeshwari H R, Dinesh Dhamecha, Satveer Jagwani, Dhanashree Patil, Satisha Hegde, Raksha Potdar, Renuka Metgud, Sunil Jalalpure, Subarna Roy, Kiran Jadhav, Neeraj Kumar Tiwari, Sravani Koduru, Shweta Hugar, Suneel Dodamani
The present work aims to investigate the efficacy of thermoreversible gel of cranberry juice concentrate (CJC) as local drug delivery for the treatment of periodontitis. CJC was initially tested for its antimicrobial activities like MIC, MBC, antiadhesion, antibiofilm and time kill assay against the panel of organisms (S. mutans (SM), E. faecalis (EF), A. actinomycetemcomitans (AA), P. gingivalis (PG), T. forsythia (TF)) responsible for periapical and periodontal infections. Antimicrobial activity of CJC showed MIC value of 50mg/ml and MBC value of 100mg/ml with desirable antiadhesion (83-90%) and antibiofilm activity (70-85%)...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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