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Chlorhexidine

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https://www.readbyqxmd.com/read/28088171/assessing-the-sustainability-of-daily-chlorhexidine-bathing-in-the-intensive-care-unit-of-a-veteran-s-hospital-by-examining-nurses-perspectives-and-experiences
#1
Jackson S Musuuza, Tonya J Roberts, Pascale Carayon, Nasia Safdar
BACKGROUND: Daily bathing with chlorhexidine gluconate (CHG) of intensive care unit (ICU) patients has been shown to reduce healthcare-associated infections and colonization by multidrug resistant organisms. The objective of this project was to describe the process of daily CHG bathing and identify the barriers and facilitators that can influence its successful adoption and sustainability in an ICU of a Veterans Administration Hospital. METHODS: We conducted 26 semi-structured interviews with a convenience sample of 4 nurse managers (NMs), 13 registered nurses (RNs) and 9 health care technicians (HCTs) working in the ICU...
January 14, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28087617/in-vitro-activity-of-the-antiasthmatic-drug-zafirlukast-against-the-oral-pathogens-porphyromonas-gingivalis-and-streptococcus-mutans
#2
Evelien Gerits, Isolde Van der Massen, Katleen Vandamme, Kaat De Cremer, Katrijn De Brucker, Karin Thevissen, Bruno P A Cammue, Serge Beullens, Maarten Fauvart, Natalie Verstraeten, Jan Michiels
Oral infections are among the most common diseases worldwide. Many protocols for the prevention and treatment of oral infections have been described, yet no golden standard has been developed so far. The antiseptic chlorhexidine and antibiotics are often used in these treatment procedures. However, long-term use of chlorhexidine can lead to side effects and extensive use of antibiotics can promote the development of antibiotic-resistant bacteria, which in turn can compromise the effectiveness of the treatment...
January 12, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28081572/exposed-dentin-influence-of-cleaning-procedures-and-simulated-pulpal-pressure-on-bond-strength-of-a-universal-adhesive-system
#3
Simon Flury, Anne Peutzfeldt, Patrick R Schmidlin, Adrian Lussi
PURPOSE: To compare various pre-treatments serving as cleaning procedures of dentin on the bond strength of resin composite promoted by a universal adhesive system applied either in the absence or presence of simulated pulpal pressure. MATERIALS AND METHODS: Prior to application of the adhesive system (Scotchbond Universal) and resin composite (Filtek Z250), ground dentin surfaces were given one of five pre-treatments either without or with simulated pulpal pressure: 1) no pre-treatment, adhesive system in "self-etch" mode, 2) phosphoric acid etching, adhesive system in "total-etch" mode, 3) polishing with pumice on prophylaxis cup, 4) air abrasion with AIR-FLOW PLUS powder, 5) air abrasion with AIR-FLOW PERIO powder; n = 20/group of pre-treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28078871/anti-plaque-and-antimicrobial-efficiency-of-different-oral-rinses-in-a-3-day-plaque-accumulation-model
#4
S Cantore, A Ballini, G Mori, V Dibello, M Marrelli, R Mirgaldi, D De Vito, M Tatullo
The idea of incorporating a mouthrinse with normal tooth brushing could be a useful adjunct to oral hygiene. Despite the principle nature of the toothpaste vehicle, most alcohol-based chemical plaque-control agents have been evaluated and later formulated in the mouthrinse vehicle. The current study was aimed to investigate the persistence of antimicrobial action and plaque inhibitory properties of a new alcohol-free mouthrinse when compared with positive control, chlorhexidine 0.12% and placebo control, physiologic saline solution mouthrinses...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28076651/controlled-release-of-chlorhexidine-from-a-mesoporous-silica-containing-macroporous-titanium-dental-implant-prevents-microbial-biofilm-formation
#5
K De Cremer, A Braem, E Gerits, K De Brucker, K Vandamme, J A Martens, J Michiels, J Vleugels, B P Cammue, K Thevissen
Roughened surfaces are increasingly being used for dental implant applications as the enlarged contact area improves bone cell anchorage, thereby facilitating osseointegration. However, the additional surface area also entails a higher risk for the development of biofilm associated infections, an etiologic factor for many dental ailments, including peri-implantitis. To overcome this problem, we designed a dental implant composed of a porous titanium-silica (Ti/SiO2) composite material and containing an internal reservoir that can be loaded with antimicrobial compounds...
January 11, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28076495/antimicrobial-activity-of-ozone-and-naf-chlorhexidine-on-early-childhood-caries
#6
Marcos Ximenes, Mariane Cardoso, Fernando Astorga, Roland Arnold, Luiz André Pimenta, Ricardo de Sousa Viera
An early childhood carie (ECC) is an extremely destructive form of tooth decay. The aim of this study was to investigate the action of ozone (O3), and the association of sodium fluoride (NaF) with chlorhexidine (CHX) on bacteria related to ECC. Overnight culture of the bacteria was performed. On exponential phase the suspension was adjusted (101-108 CFU/mL). A drop (10μL) of each concentration of bacteria was applied on sheep blood agar plates and treated with O3 (2, 20, 200, and 2,000 ppm); after 18 hours, recovery analysis of CFU verified the reduction of bacterial activity...
January 5, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28076463/in-vitro-effects-of-melaleuca-alternifolia-essential-oil-on-growth-and-production-of-volatile-sulphur-compounds-by-oral-bacteria
#7
Talita Signoreti Graziano, Caroline Morini Calil, Adilson Sartoratto, Gilson César Nobre Franco, Francisco Carlos Groppo, Karina Cogo-Müller
Objective: Halitosis can be caused by microorganisms that produce volatile sulphur compounds (VSCs), which colonize the surface of the tongue and subgingival sites. Studies have reported that the use of natural products can reduce the bacterial load and, consequently, the development of halitosis. The aim of this study was to evaluate the antimicrobial activity of the essential oil of Melaleuca alternifolia on the growth and volatile sulphur compound (VSC) production of oral bacteria compared with chlorhexidine...
November 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28075506/efficacy-of-chlorhexidine-for-the-prevention-and-treatment-of-oral-mucositis-in-cancer-patients-a-systematic-review-with-meta-analyses
#8
REVIEW
Alvin Cardona, Amir Balouch, Moiz A Mohammed, Parish P Sedghizadeh, Reyes Enciso
BACKGROUND: Oral mucositis occurs in patients undergoing chemoradiation for cancer treatment. It is believed that colonization of ulcerated mucosa by bacteria, fungi and virus results in secondary infections. The effect of chlorhexidine (CHX) on the incidence and severity of oral mucositis in cancer patients was evaluated in this review. METHODS: Studies were limited to randomized placebo-controlled trials. Three databases were searched: MEDLINE (via PubMed), Web of Science and the Cochrane Library up to May 25, 2016...
January 11, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28072890/candida-albicans-survival-growth-and-biofilm-formation-are-differently-affected-by-mouthwashes-an-in-vitro-study
#9
Simona Paulone, Giulia Malavasi, Andrea Ardizzoni, Carlotta Francesca Orsi, Samuele Peppoloni, Rachele Giovanna Neglia, Elisabetta Blasi
Candida albicans is the most common cause of oral mycoses. The aim of the present study was to investigate in vitro the susceptibility of C. albicans to mouthwashes, in terms of growth, survival and biofilm formation. Candida albicans, laboratory strain SC5314, and 7 commercial mouthwashes were employed: 3 with 0.2% chlorhexidine digluconate; 1 with 0.06% chlorhexidine digluconate and 250 ppm F- sodium fluoride; 3 with fluorine-containing molecules. None of the mouthwashes contained ethanol in their formulations...
January 9, 2017: New Microbiologica
https://www.readbyqxmd.com/read/28072624/the-effect-of-antiseptic-on-99mtc-dmsa-scans
#10
Tahereh Firuzyar, Tahereh Ghaedian
Approximately 30 years ago, it has been suggested that chlorhexidine, which is used as antiseptic, can produce Tc colloid complex during Tc-dimercaptosuccinic acid (DMSA) preparation. However, in all cases of liver and spleen uptake in Tc-DMSA scan, it should still be kept in mind because of the introduction of new antiseptic brands with different formulation under various names. Our case is just a sample of this effect, which resulted from application of a new brand of antiseptic by technologists in our center that unintentionally led to low-quality Tc-DMSA scans for a period, and after restrict control of all other confounding factors in the preparation of kit, it was just resolved by changing antiseptic to ethanol...
January 9, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28068508/avoiding-chlorhexidine-burns-in-preterm-infants
#11
Mariano Paternoster, Massimo Niola, Vincenzo Graziano
Chlorhexidine is a skin antiseptic agent frequently used for off-label indications in NICUs. Changes to the safety labeling of chlorhexidine products for use in preterm infants were recently made because of the risk of severe chemical burns. We provide tips for a safer use of chlorhexidine to prevent injury in newborns and to help health care professionals protect themselves against burn injury claims.
January 6, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28067105/antimicrobial-effects-of-mastic-extract-against-oral-and-periodontal-pathogens
#12
Stefka Koychev, Henrik Dommisch, Hong Chen, Nicole Pischon
BACKGROUND: Various antimicrobial agents are widely used in the therapy of oral inflammatory diseases. However, their side effects and the appearance of drug resistance justify research on natural antimicrobial agents to target oral pathogens that are safe for the host. In the present study, antimicrobial properties of mastic extract on commensal and pathogenic oral bacteria, as well as its possible cytotoxic effect toward cells of epithelial and mesenchymal origin, were evaluated in comparison to the common antimicrobial agents hydrogen peroxide (H2O2) and chlorhexidine digluconate (CHX)...
January 8, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28067086/-prospective-randomized-study-regarding-the-effect-of-the-preoperative-antibiotic-and-chlorhexidine-rinse-on-wound-healing-after-mandibular-third-molar-surgery
#13
István Kaposvári, Kinga Körmöczi, Zsuzsa Beáta László, Ferenc Oberna, Ferenc Horváth, Árpád Joób-Fancsaly
INTRODUCTION AND AIM: The study compares the antibiotic prophylaxis combined with postoperative antibiotic therapy to preoperative chlorhexidine rinse combined with postoperative antibiotic therapy in preventing complications after surgical removal of a mandibular third molar. METHOD: 71 healthy patients in four groups were enrolled in the study: I. prophylactic dose of 2000 mg of amoxicillin clavulanate, continued with amoxicillin clavulanate postoperatively; II...
January 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28064012/effect-of-a-novel-quaternary-ammonium-silane-on-dentin-protease-activities
#14
D Umer, C K Y Yiu, M F Burrow, L-N Niu, F R Tay
OBJECTIVES: Demineralized dentin collagen release C-terminal cross-linked telopeptide (ICTP) and C-terminal peptide (CTX) during degradation. The present study evaluated the effects of dentin pre-treatment with K21, a quaternary ammonium silane (QAS), on matrix metalloproteinase (MMP) and cathepsin K-mediated collagen degradation. METHODS: Dentin beams were demineralized with 10% H3PO4 for 24h. After baseline dry mass measurements, the beams were divided into 5 groups (N=10) according to protease inhibitors...
January 4, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28063726/hospital-wide-chlorhexidine-gluconate-bed-bathing-protocol-a-cross-sectional-study-in-a-single-hospital
#15
Sara M Reese, Nicole Burnet, Jan Smith, Heather Escudero, Bryan C Knepper, Heather L Young
The objective of this study was to determine understanding of bed bathing practices over time after the implementation of a standardized bed bathing protocol. An online survey addressing bathing practices was administered preintervention and 6 and 18 months postintervention to all nurses and technicians caring for adult patients. Survey responses suggested that the intervention resulted in sustained understanding of the standardized bed bathing protocol.
January 5, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28052784/reducing-the-rate-of-surgical-site-infections-after-breast-surgery-with-the-use-of-larger-volumes-of-4-chlorhexidine-gluconate-solution-as-preoperative-antiseptic-showering
#16
Jon Persichino, Hayley Lee, Made Sutjita, Karla Talavera, Glenn San-Agustin, Silvia Gnass
No abstract text is available yet for this article.
January 5, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28049050/montmorillonite-chitosan-chlorhexidine-composite-films-with-antibiofilm-activity-and-improved-cytotoxicity-for-wound-dressing
#17
Valeria Ambrogi, Donatella Pietrella, Morena Nocchetti, Serena Casagrande, Veronica Moretti, Stefania De Marco, Maurizio Ricci
HYPOTHESIS: Chlorhexidine (CLX) is a good antimicrobial agent, but its use in treatment of wounds is limited because of its cytotoxicity towards human fibroblasts. A delivery system, able to release CLX in a localized and prolonged manner, could guarantee antimicrobial activity with reduced cytotoxic. Thus in this work the preparation and characterization of chitosan/montmorillonite composite films containing CLX, able to offer a prolonged CLX release, is described. The antimicrobial and antibiofilm activities and cytotoxicity of films were investigated...
December 24, 2016: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28045704/neonatal-peripherally-inserted-central-catheter-practices-and-providers-results-from-the-neonatal-picc1-survey
#18
Elizabeth Sharpe, Latoya Kuhn, David Ratz, Sarah L Krein, Vineet Chopra
BACKGROUND: Neonatal intensive care units (NICUs) commonly utilize peripherally inserted central catheters (PICCs) to provide nutrition and long-term medications to premature and full-term infants. However, little is known about PICC practices in these settings. PURPOSE: To assess PICC practices, policies, and providers in NICUs. METHODS: The Neonatal PICC1 Survey was conducted through the use of the electronic mailing list of a national neonatal professional organization's electronic membership community...
December 29, 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28043532/evaluation-of-sodium-hydroxide-n-acetyl-l-cysteine-and-0-7-chlorhexidine-decontamination-methods-for-recovering-mycobacterium-tuberculosis-from-sputum-samples-a-comparative-analysis-the-gambia-experience
#19
Ensa Gitteh, Jacob Kweku Otu, Tijan Jobarteh, Francis Mendy, Isatou Tutty Faal-Jawara, Nana Boatema Ofori-Anyinam, Abigail Ayorinde, Ousman Secka, Florian Gehre
OBJECTIVE/BACKGROUND: To determine the culture yield and time to detection of mycobacterial growth between samples decontaminated using 0.7% chlorhexidine and sodium hydroxide-N-acetyl-l-cysteine (NaOH-NALC) and cultured on the Löwenstein-Jensen (LJ) medium. We also aimed to determine the contamination rate between the 0.7% chlorhexidine and NaOH-NALC decontamination methods. METHODS: The study was carried out on 68 sputa samples (42 smear positives and 26 smear negatives)...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28042447/effectiveness-of-two-different-desensitizing-varnishes-in-reducing-tooth-sensitivity-a-randomized-double-blind-clinical-trial
#20
G M Nardi, S Sabatini, D Lauritano, F Silvestre, M Petruzzi
PURPOSE: The aim of this study is to evaluate and compare the effectiveness of two different desensitizing varnishes. MATERIALS AND METHODS: Ninety healthy adults suffering from tooth sensitivity were divided into three groups. Two different varnishes were used for the study: Fluor Protector S, containing 7700 ppm fluoride (group I), and Cervitec F, containing 1400 ppm fluoride and 0.3% chlorhexidine (group II). A placebo containing water and ethanol was applied for the third group...
October 2016: Oral & Implantology
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