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https://www.readbyqxmd.com/read/28616481/evidence-of-exposure-to-rickettsia-felis-in-australian-patients
#1
Yen Thon Teoh, Sze Fui Hii, Stephen Graves, Robert Rees, John Stenos, Rebecca J Traub
Rickettsia felis is an emerging zoonosis, causing flea-borne spotted fever (FBSF). Serological diagnosis is typically confounded by cross-reactivity with typhus group rickettsiae and prior to the development of specific serological methods, cases of FBSF in Australia were misdiagnosed. Patient sera tested between August 2010 and December 2013 and known to be seropositive to R. typhi by immunofluorescence antibody testing (IFAT) were subsequently retested against R. felis using an R. felis-specific IFAT. Sera of 49 patients were of a sufficient quality to be included in re-analysis...
December 2016: One Health
https://www.readbyqxmd.com/read/28612320/scrub-typhus-causing-neonatal-hepatitis-with-acute-liver-failure-a-case-series
#2
Shailja Vajpayee, R K Gupta, M L Gupta
Neonatal hepatitis with acute liver failure due to varied etiology including various infections is reported in the past. Scrub typhus as a cause of neonatal hepatitis has rarely been reported in literature. A high index of clinical suspicion is required for early diagnosis and timely treatment. Severity and prognosis of the disease varies widely because several different strains of Orientia tsutsugamushi exist with different virulence. Delayed diagnosis can result in complication and significant morbidity and mortality...
June 14, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28607239/scrub-typhus-in-bhutan-a-synthesis-of-data-from-2009-to-2014
#3
REVIEW
Tshokey Tshokey, Tashi Choden, Ragunath Sharma
Scrub typhus is an acute, febrile illness, caused by the bacterium Orientia tsutsugamushi, that affects millions annually in the endemic Asia-Pacific region. In untreated cases, the case-fatality rates range from 6% to 35%. In Bhutan, there was a probable outbreak in Gedu in 2009, which resulted in heightened awareness of the disease. Nevertheless, information on scrub typhus in Bhutan is limited and scattered and the epidemiology has yet to be established. To report the current picture of scrub typhus in Bhutan, this review gathered data from scholarly databases, surveillance reports, the Annual health bulletin, research publications and laboratory test reports from hospitals...
September 2016: WHO South-East Asia Journal of Public Health
https://www.readbyqxmd.com/read/28604564/acute-cerebellitis-in-a-child-with-scrub-typhus
#4
Siyaram Didel, Aseem Basha M, Manisha Biswal, Renu Suthar, Naveen Sankhyan
No abstract text is available yet for this article.
July 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28601091/an-elisa-assay-using-a-combination-of-recombinant-proteins-from-multiple-strains-of-orientia-tsutsugamushi-offers-an-accurate-diagnosis-for-scrub-typhus
#5
Chien-Chung Chao, Zhiwen Zhang, Tatyana Belinskaya, Wilawan Thipmontree, Wiwit Tantibhedyangkul, Saowaluk Silpasakorn, Ekkarat Wongsawat, Yupin Suputtamongkol, Wei-Mei Ching
BACKGROUND: Scrub typhus (ST) is a disease caused by an obligate intracellular bacterium, Orientia tsutsugamushi, an organism that requires a BSL3 laboratory for propagation. The disease is hallmarked by an eschar at the site of the chigger bite, followed by the development of fever, malaise, myalgia, anorexia, and papulomacular rash. Indirect immunofluorescent assay (IFA) is the gold standard for scrub typhus diagnosis, however, the subjectivity of the assay, the need for a specialized laboratory and instruments has limited the wide use of the test in resource limited areas...
June 10, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28584437/severe-pediatric-acute-respiratory-distress-syndrome-due-to-scrub-typhus-successful-ventilation-with-airway-pressure-release-ventilation-mode-after-becoming-refractory-to-protective-ventilation
#6
Sudha Chandelia, Sarika Jain
Scrub typhus can affect lungs from mild illness like pneumonitis to a severe illness like acute respiratory distress syndrome (ARDS). Such patients may be very challenging to treat when their hypoxemia becomes severe and refractory to treatment. Main treatment is supportive in terms of mechanical ventilation. In adult ARDS, low tidal volume (TV) ventilation has been recommended, but there is no consensus on most effective ventilation mode in children. We present a case of a 12-year-old girl who developed severe ARDS (PO2/FiO2 ratio - 58), refractory to low TV ventilation...
May 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28560173/severe-interstitial-pneumonia-due-to-murine-typhus-in-a-patient-returning-from-bali
#7
Luís Malheiro, Filipa Ceia, João Alves, Ana Cláudia Carvalho, Joana Sobrinho-Simões, Rita Sousa, António Sarmento, Lurdes Santos
Murine typhus has been increasingly reported as a cause of fever in returning travelers from Southeast Asia. We report a case of a previously healthy traveler returning from Bali with an non-specific febrile illness which quickly progressed to a severe form of interstitial pneumonia. After a careful epidemiological evaluation and laboratory analysis, murine typhus was diagnosed.
2017: IDCases
https://www.readbyqxmd.com/read/28539197/candidatus-neoehrlichia-mikurensis-and-borrelia-burgdorferi-sensu-lato-detected-in-the-blood-of-norwegian-patients-with-erythema-migrans
#8
H Quarsten, A Grankvist, L Høyvoll, I B Myre, T Skarpaas, V Kjelland, C Wenneras, S Noraas
The most common tick-borne human disease in Norway is Lyme borreliosis. Ticks in Norway also harbour less known disease-causing agents such as Candidatus Neoehrlichia mikurensis, Borrelia miyamotoi and Rickettsia helvetica. However, human infections caused by these pathogens have never been described in Norway. The main aims of the study were to evaluate the contribution of several tick-borne bacterial agents, other than Borrelia burgdorferi sensu lato, to zoonotic diseases in Norway and to determine their clinical pictures...
May 13, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28531311/the-genotypes-of-orientia-tsutsugamushi-identified-in-scrub-typhus-patients-in-northern-vietnam
#9
Hang L K Nguyen, Hang T T Pham, Tinh V Nguyen, Phuong Vm Hoang, Mai T Q Le, Taichiro Takemura, Futoshi Hasebe, Daisuke Hayasaka, Akio Yamada, Kozue Hotta
Background: There are an estimated one million patients with scrub typhus in the Asia-Pacific region. There are few reports describing the incidence of scrub typhus in Vietnam. Methods: Blood samples collected from 63 patients clinically diagnosed as having scrub typhus from July 2015 to September 2016 were subjected to genotyping of Orientia tsutsugamushi. Results and Conclusions: Of these patients, 42 (67%) tested positive for O. tsutsugamushi, and the most common genotype was identified to be Karp (55%)...
March 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28529271/evidence-of-infection-with-leptospira-interrogans-and-spotted-fever-group-rickettsiae-among-rodents-in-an-urban-area-of-osaka-city-japan
#10
Kenta Shimizu, Rie Isozumi, Kazutoshi Takami, Isao Kimata, Kanae Shiokawa, Kumiko Yoshimatsu, Yoshimi Tsuda, Sanae Nishio, Jiro Arikawa
We examined 33 rodents captured in an urban area of Osaka City, Japan for IgG antibodies against Seoul virus, severe fever with thrombocytopenia syndrome virus, hepatitis E virus, Leptospira interrogans, Yersinia pestis, spotted fever, typhus and scrub typhus group rickettsiae. We found that 3 (9.1%) and 1 (3.0%) of the 33 rodents had antibodies against L. interrogans and spotted fever group rickettsiae, respectively. DNAs of leptospires were detected from 2 of the 3 seropositive rodents, but DNA of rickettsia was not detected...
May 22, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28500808/seroprevalence-of-scrub-typhus-typhus-and-spotted-fever-among-rural-and-urban-populations-of-northern-vietnam
#11
Nguyen Vu Trung, Le Thi Hoi, Nguyen Thi Hong Thuong, Tran Khanh Toan, Tran Thi Kieu Huong, Tran Mai Hoa, Annette Fox, Nguyen van Kinh, H Rogier van Doorn, Heiman F L Wertheim, Juliet E Bryant, Behzad Nadjm
AbstractRickettsial infections are recognized as important causes of fever throughout southeast Asia. Herein, we determined the seroprevalence to rickettsioses within rural and urban populations of northern Vietnam. Prevalence of individuals with evidence of prior rickettsial infections (IgG positive) was surprisingly low, with 9.14% (83/908) testing positive to the three major rickettsial serogroups thought to circulate in the region. Prevalence of typhus group rickettsiae (TG)-specific antibodies (6.5%, 58/908) was significantly greater than scrub typhus group orientiae (STG)- or spotted fever group rickettsiae (SFG)-specific antibodies (P < 0...
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28500798/persistent-sick-sinus-syndrome-in-scrub-typhus
#12
Lae-Young Jung, Ji-Young Yoon, Soo-Kyeong Song, Chang-Seop Lee
No abstract text is available yet for this article.
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28500797/fatal-flea-borne-typhus-in-texas-a-retrospective-case-series-1985-2015
#13
Emily G Pieracci, Nicole Evert, Naomi A Drexler, Bonny Mayes, Inger Vilcins, Philip Huang, Jill Campbell, Casey Barton Behravesh, Christopher D Paddock
AbstractFlea-borne (murine) typhus is a global rickettsiosis caused by Rickettsia typhi. Although flea-borne typhus is no longer nationally notifiable, cases are reported for surveillance purposes in a few U.S. states. The infection is typically self-limiting, but may be severe or life-threatening in some patients. We performed a retrospective review of confirmed or probable cases of fatal flea-borne typhus reported to the Texas Department of State Health Services during 1985-2015. When available, medical charts were also examined...
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28474627/scrub-typhus-in-uttarakhand-adjoining-uttar-pradesh-seasonality-clinical-presentations-predictors-of-mortality
#14
Anurag Bhargava, Reshma Kaushik, Rajeev Mohan Kaushik, Anita Sharma, Sohaib Ahmad, Minakshi Dhar, Garima Mittal, Sushant Khanduri, Priyannk Pant, Rajesh Kakkar
BACKGROUND & OBJECTIVES: Scrub typhus is a re-emerging mite-borne rickettsiosis, which continues to be underdiagnosed, with lethal consequences. The present study was conducted to determine the seasonality, clinical presentation and predictors of mortality in patients with scrub typhus at a tertiary care teaching hospital in northern India. METHODS: Scrub typhus was suspected in patients attending the hospital as per the standard case definition and serological evidence was obtained by performing an IgM ELISA...
December 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28474626/abundance-distribution-of-trombiculid-mites-orientia-tsutsugamushi-the-vectors-pathogen-of-scrub-typhus-in-rodents-shrews-collected-from-puducherry-tamil-nadu-india
#15
Sadanandane Candasamy, Elango Ayyanar, Kummankottil Paily, Patricia Anitha Karthikeyan, Agatheswaran Sundararajan, Jambulingam Purushothaman
BACKGROUND & OBJECTIVES: Human cases of scrub typhus are reported every year from Puducherry and adjoining areas in southern India. However, information on the presence of causative agent, Orientia tsutsugamushi, and its vectors is lacking. Hence, the objective of the study was to find out the vector as well as pathogen distribution in rodents and shrews present in the scrub typhus-reported areas in southern India. METHODS: Trombiculid mites were collected by combing rats and shrews collected using Sherman traps and identified to species level following standard taxonomical keys...
December 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28473857/severe-murine-typhus-presenting-with-acalculous-cholecystitis-a-case-report-and-literature-review
#16
Nikolaos Spernovasilis, Constantinos Tsioutis, Maria Zafeiri, Georgios Hamilos, Achilleas Gikas
A 54-year-old otherwise healthy male, who was being evaluated for prolonged fever, developed clinical and ultrasonographic signs compatible with acute acalculous cholecystitis. Diagnosis of murine typhus was confirmed by serology and the patient was treated with doxycycline. He improved rapidly and all clinical and laboratory abnormalities returned to normal. The present case dictates that knowledge of the local epidemiology and keeping a high index of clinical suspicion can help recognize uncommon manifestations of murine typhus, in order to treat appropriately and avoid unnecessary investigations and interventions...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28468110/-brief-history-of-the-first-hospital-of-harbin-city-1913-2013
#17
Y Ji, Z P Li
In 1913, after the Russian Prostitutes Sanatorium of Harbin Eastern Railway was received by the board of directors, they established the "Harbin City Board Hospital" and funded its expansion. In March 1926, the provisional Committee of the Harbin autonomous renamed the "City Board of First Hospital" to "The Public Hospital" . In November 1926, "The Public Hospital" was renamed as "Harbin Special Municipal Hospital" by the Harbin City Council and further funds were invested in its construction. In 1931, the Japanese invaded Northeast China, and controlled the "City Hospital" ...
March 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28467406/correction-significance-of-major-international-seaports-in-the-distribution-of-murine-typhus-in-taiwan
#18
Chi-Chien Kuo, Nicola Wardrop, Chung-Te Chang, Hsi-Chieh Wang, Peter M Atkinson
[This corrects the article DOI: 10.1371/journal.pntd.0005430.].
May 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28461826/effects-of-clarithromycin-treatment-in-scrub-typhus-in-children-comparison-with-chloramphenicol-and-azithromycin
#19
Min Lee, June Kim, Dae Sun Jo
PURPOSE: Chloramphenicol and tetracycline are not recommended for treating scrub typhus in pediatric patients because of potential side effects, such as aplastic anemia or tooth discoloration. While clarithromycin has recently been used in adults, few reports have been published on its effects in pediatric patients. We report the clinical profiles of pediatric scrub typhus and the effects of clarithromycin on scrub typhus in children. METHODS: We retrospectively analyzed medical records of 56 children with scrub typhus who were admitted between 2004 and 2013 to Chonbuk National University Hospital, Jeonju, Korea...
April 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/28457356/rickettsiae-as-emerging-infectious-agents
#20
REVIEW
Rong Fang, Lucas S Blanton, David H Walker
With advances in molecular genetics, more pathogenic rickettsial species have been identified. Pathogenic rickettsiae are transmitted by vectors, such as arthropods, into the patient's skin and then spread into the microvascular endothelial cells. Clinical manifestations are characterized by fever with headache and myalgias, followed by rash 3 to 5 days later. The undifferentiated nature of clinical symptoms, knowledge of the epidemiology, and the patient's history of travel and exposure to arthropod vectors are critical to the empiric administration of antimicrobial therapy...
June 2017: Clinics in Laboratory Medicine
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