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https://www.readbyqxmd.com/read/27928094/seroconversion-to-causes-of-febrile-illness-in-mongolian-peacekeepers-deployed-to-south-sudan
#1
Altangerel Enkhtsetseg, Rendoo Davadoorj, Stefan Fernandez, Duangrat Mongkolsirichaikul, Damdin Altantuul, Erdene Elbegdorj, Lkhagvasuren Ganchimeg, Samuel L Yingst
Immediately before deployment (Fall 2012) and after deployment (Spring 2013) in support of United Nations peacekeeping operations, Mongolian Armed Forces medical personnel obtained serum samples from the first contingent of Mongolian peacekeepers deploying to South Sudan to monitor serologic evidence of exposure to diseases that cause acute febrile illness. A total of 632 paired samples were tested for IgG antibody for the following (number of seroconversions in parentheses): Rickettsia (spotted fever and typhus groups) (25), West Nile fever virus (WNV) (23), Coxiella burnetii (causative agent of Q fever) (12), dengue virus (8), leptospirosis (6), chikungunya virus (0), Congo-Crimean hemorrhagic fever virus (0), Japanese encephalitis virus (0), and Rift Valley fever virus (0)...
December 7, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27928073/evolution-of-eschar-in-scrub-typhus
#2
Jin Park, Soo-Han Woo, Chang-Seop Lee
No abstract text is available yet for this article.
December 7, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27924792/a-cost-effective-approach-to-the-diagnosis-and-management-of-acute-infectious-encephalitis
#3
Usha Kant Misra, Vinita Elizabeth Mani, Jayantee Kalita
SETTING: A tertiary care teaching hospital in India. OBJECTIVE: To report a syndromic approach to acute encephalitis syndrome (AES) and propose a cost-effective model. STUDY DESIGN: AES patients were categorized by the presence or absence of myalgia/rash into systemic and neurological AES. The patients with systemic AES were investigated for dengue, scrub typhus, leptospira, chikungunya, and malaria, and those with neurological AES were investigated for herpes and Japanese encephalitis (JE)...
December 8, 2016: European Neurology
https://www.readbyqxmd.com/read/27908651/eschar-a-stepping-stone-to-scrub-typhus
#4
Shu-Chao Weng, Hung-Chang Lee, Jeng-Jung Chen, Yu-Jyun Cheng, Hsin Chi, Chien-Yu Lin
No abstract text is available yet for this article.
November 28, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27905346/bevacizumab-in-choroidal-neovascularization-secondary-to-indian-tick-typhus-a-rare-case-report
#5
Raghavendra Ijeri, Gautam Beladiya, Sharad Bhomaj
Tick typhus causes hemorrhagic lesions over the skin. Retina also shows hemorrhages and exudates. Many cases have been reported in western literature about this condition. To our best of knowledge, this is the first case report of tick typhus in India which was also associated with inflammatory choroidal neovascularization.
October 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27887623/generation-of-protective-immunity-against-orientia-tsutsugamushi-infection-by-immunization-with-a-zinc-oxide-nanoparticle-combined-with-scaa-antigen
#6
Na-Young Ha, Hyun Mu Shin, Prashant Sharma, Hyun Ah Cho, Chan-Ki Min, Hong-Il Kim, Nguyen Thi Hai Yen, Jae-Seung Kang, Ik-Sang Kim, Myung-Sik Choi, Young Keun Kim, Nam-Hyuk Cho
BACKGROUND: Zinc oxide nanoparticle (ZNP) has been applied in various biomedical fields. Here, we investigated the usage of ZNP as an antigen carrier for vaccine development by combining a high affinity peptide to ZNP. RESULTS: A novel zinc oxide-binding peptide (ZBP), FPYPGGDA, with high affinity to ZNP (K a  = 2.26 × 10(6) M(-1)) was isolated from a random peptide library and fused with a bacterial antigen, ScaA of Orientia tsutsugamushi, the causative agent of scrub typhus...
November 26, 2016: Journal of Nanobiotechnology
https://www.readbyqxmd.com/read/27886863/analysis-of-scrub-typhus-involvement-of-the-lung-by-bronchoalveolar-lavage-a-case-report
#7
Shih-Yuan Lin, Yosuke Matsuno, Masahiro Yokosawa, Takeshi Suzuki, Yuko Morishima, Tohru Sakamoto, Takayuki Sumida, Nobuyuki Hizawa
No abstract text is available yet for this article.
November 2016: Respiratory Investigation
https://www.readbyqxmd.com/read/27885295/scrub-typhus-an-emerging-neglected-tropical-disease-in-nepal
#8
B P Upadhyaya, G Shakya, S Adhikari, N Rijal, J Acharya, L Maharjan, B R Marasini
BACKGROUND: Scrub typhus is a neglected tropical disease and is under reported from Nepal. The objective of this study was to investigate the sero-epidemiology of scrub typhus in patients suffering from acute febrile illness. METHODS: A total of 434 specimens collected from July to November 2015 at National Public Health Laboratory (NPHL) were investigated for detection of immunoglobulin M (IgM) antibody to Orientiatsutsugamushi.The Scrub Typhus Detect TM kit (InBios, USA) was used to detect the antibodies to O...
May 2016: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/27883370/epstein-barr-virus-associated-hemophagocytic-syndrome-after-scrub-typhus-infection
#9
Jeong Woo Hong, Hyun Seon You, Tae Won Lee, Won Yong Jo, Bo Ra Kim, Young Sun Suh, In Gyu Bae, Oh Hyun Cho
There have been a small number of cases of scrub typhus-associated hemophagocytic syndrome (HPS), most of which were treated successfully using adequate antibiotics. Here, we report a case of Epstein-Barr virus (EBV)-associated HPS after scrub typhus infection that was not improved using antirickettsial treatment. A 73-year-old male who had been diagnosed with scrub typhus according to an eschar and a positive serology was transferred to our institution because of a persistent fever despite 7-day doxycycline therapy...
November 8, 2016: Infection & Chemotherapy
https://www.readbyqxmd.com/read/27875529/cd4-t-cells-are-as-protective-as-cd8-t-cells-against-rickettsia-typhi-infection-by-activating-macrophage-bactericidal-activity
#10
Kristin Moderzynski, Stefanie Papp, Jessica Rauch, Liza Heine, Svenja Kuehl, Ulricke Richardt, Bernhard Fleischer, Anke Osterloh
Rickettsia typhi is an intracellular bacterium that causes endemic typhus, a febrile disease that can be fatal due to complications including pneumonia, hepatitis and meningoencephalitis, the latter being a regular outcome in T and B cell-deficient C57BL/6 RAG1-/- mice upon Rickettsia typhi infection. Here, we show that CD4+ TH1 cells that are generated in C57BL/6 mice upon R. typhi infection are as protective as cytotoxic CD8+ T cells. CD4+- as well as CD8+-deficient C57BL/6 survived the infection without showing symptoms of disease at any point in time...
November 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27834329/epidemiology-risk-factors-of-scrub-typhus-in-south-india
#11
George M Varghese, Deepa Raj, Mark R Francis, Rajiv Sarkar, Paul Trowbridge, Jayaprakash Muliyil
BACKGROUND & OBJECTIVES: Scrub typhus is a major public health threat in South and Southeastern Asian countries including India. Understanding local patterns of disease and factors that place individuals at risk is pivotal to future preventive measures against scrub typhus. The primary aim of this study was to identify specific epidemiological and geographical factors associated with an increased risk of developing scrub typhus in this region. METHODS: We mapped 709 patients from Tamil Nadu, Andhra Pradesh and Telangana who were admitted to the Christian Medical College (CMC) Hospital, Vellore, Tamil Nadu, India, for the period 2006-2011, assessed seasonality using monthly counts of scrub typhus cases, and conducted a case-control study among a subset of patients residing in Vellore...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27829876/scrub-typhus-in-pregnancy-maternal-and-fetal-outcomes
#12
Sudha J Rajan, Sowmya Sathyendra, Alice J Mathuram
Scrub typhus is an important unrecognized cause for undifferentiated acute febrile illness in India associated with poor fetal outcomes. Maternal and fetal outcomes among pregnant patients with scrub typhus presenting to a tertiary care university teaching hospital from January 2010 to July 2012 were studied. Scrub typhus was diagnosed by clinical criteria along with scrub ELISA positivity or an eschar. In total, 33 of 738 patients (4.5%) who were diagnosed with scrub typhus were pregnant; 57.6% were in the third trimester, 27...
December 2016: Obstetric Medicine
https://www.readbyqxmd.com/read/27790497/an-unusual-presentation-of-scrub-typhus
#13
Giridhar Reddy Banda, Srikrishna Raghavendra Boddu, Priyanka Ballal, Jayaprakash Belle
Presentation of scrub typhus associated with brachial neuritis is extremely rare with only a few cases reported so far. Here, we report a case of a 45-year-old female who presented with fever and right shoulder pain. Laboratory parameters showed leucocytosis with ELISA and PCR for scrub typhus positive. Electromyography (EMG) and Nerve Conduction Velocity (NCV) study was suggestive of brachial neuritis. She was given doxycycline therapy for 10 days following which her shoulder pain resolved.
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27788693/meteorological-factors-affecting-scrub-typhus-occurrence-a-retrospective-study-of-yamagata-prefecture-japan-1984-2014
#14
J Seto, Y Suzuki, R Nakao, K Otani, K Yahagi, K Mizuta
Climate change, by its influence on the ecology of vectors might affect the occurrence of vector-borne diseases. This study examines the effects of meteorological factors in Japan on the occurrence of scrub typhus, a mite-borne zoonosis caused by Orientia tsutsugamushi. Using negative binomial regression, we analysed the relationships between meteorological factors (including temperature, rainfall, snowfall) and spring-early summer cases of scrub typhus in Yamagata Prefecture, Japan, during 1984-2014. The average temperature in July and August of the previous year, cumulative rainfall in September of the previous year, snowfall throughout the winter, and maximum depth of snow cover in January and February were positively correlated with the number of scrub typhus cases...
October 28, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27774344/scrub-typhus-in-nepal
#15
Niranjan Nayak
No abstract text is available yet for this article.
June 2016: Nepal journal of epidemiology
https://www.readbyqxmd.com/read/27767909/severe-fever-with-thrombocytopenia-syndrome-in-patients-suspected-of-having-scrub-typhus
#16
Yu Mi Wi, Hye In Woo, Dahee Park, Keun Hwa Lee, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song
To determine prevalence of severe fever with thrombocytopenia syndrome in South Korea, we examined serum samples from patients with fever and insect bite history in scrub typhus-endemic areas. During the 2013 scrub typhus season, prevalence of this syndrome among patients suspected of having scrub typhus was high (23.0%), suggesting possible co-infection.
November 2016: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27763480/chest-radiographic-manifestations-of-scrub-typhus
#17
Kpp Abhilash, P R Mannam, K Rajendran, R A John, P Ramasami
BACKGROUND AND RATIONALE: Respiratory system involvement in scrub typhus is seen in 20-72% of patients. In endemic areas, good understanding and familiarity with the various radiologic findings of scrub typhus are essential in identifying pulmonary complications. MATERIALS AND METHODS: Patients admitted to a tertiary care center with scrub typhus between October 2012 and September 2013 and had a chest X ray done were included in the analysis. Details and radiographic findings were noted and factors associated with abnormal X-rays were analyzed...
October 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27757247/an-outbreak-investigation-of-scrub-typhus-in-western-province-solomon-islands-2014
#18
Michael Marks, Cynthia Joshua, Jenny Longbottom, Katherine Longbottom, Alison Sio, Elliot Puiahi, Greg Jilini, John Stenos, Tenneth Dalipanda, Jennie Musto
OBJECTIVE: To identify the etiology and risk factors of undifferentiated fever in a cluster of patients in Western Province, Solomon Islands, May 2014. METHODS: An outbreak investigation with a case control study was conducted. A case was defined as an inpatient in one hospital in Western Province, Solomon Islands with high fever (> 38.5 °C) and a negative malaria microscopy test admitted between 1 and 31 May 2014. Asymptomatic controls matched with the cases residentially were recruited in a ratio of 1:2...
January 2016: Western Pacific Surveillance and Response Journal: WPSAR
https://www.readbyqxmd.com/read/27753778/acute-paraparesis-due-to-lumbosacral-radiculopathy-with-concomitant-meningitis-unusual-presentation-of-scrub-typhus
#19
Mamta Muranjan, Sunil Karande
No abstract text is available yet for this article.
November 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27743443/an-overview-of-epidemic-typhus-in-the-world-and-iran-during-the-19th-and-20th-centuries
#20
Mohammad Hossein Azizi, Moslem Bahadori, Farzaneh Azizi
The present article provides a concise historical review on classical epidemic typhus (exanthemata typhus) in the world as well its outbreaks in Iran mainly during the 19th and 20th centuries. Typhus is still a potential public health threat under certain conditions, despite the fact that nowadays, efficient antibiotics are accessible and sanitary conditions which lead to typhus outbreaks have improved significantly.
October 2016: Archives of Iranian Medicine
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