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Acute myocardial infarction

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https://www.readbyqxmd.com/read/29223947/-trigeminy-of-ventricular-bigeminy-caused-by-reentrant-mechanism-reentry-of-reentry
#1
Oscar A Pellizzón, Marcelo V Elizari
The process that follows an acute myocardial infarction generates an appropriate substrate for the formation of reentry circuits, considered to be the most frequent mechanism of ventricular extrasystoles and tachyarrhythmias. We present the case of a patient with an acute myocardial infarction unusually concurring with ventricular trigeminy coupled to ventricular bigeminated extrasystoles giving rise to a trigeminy sequence over the bigeminy, which indicates the existence of two reentry circuits (reentry of reentry) that trigger ventricular flutter...
2017: Medicina
https://www.readbyqxmd.com/read/29223872/relationship-between-thrombus-age-in-aspirated-coronary-material-and-mid-term-major-adverse-cardiac-and-cerebrovascular-events-in-patients-with-acute-myocardial-infarction
#2
Kensaku Nishihira, Yoshisato Shibata, Atsushi Yamashita, Nehiro Kuriyama, Yujiro Asada
BACKGROUND AND AIMS: Recent studies have shown that coronary thrombus histopathology is associated with impaired myocardial reperfusion and poor clinical outcome in patients with acute myocardial infarction (AMI). We sought to investigate the age of thrombi aspirated during percutaneous coronary intervention (PCI) in patients with AMI and evaluate the relationship between histopathologic findings and major adverse cardiac and cerebrovascular events (MACCEs) defined as all-cause death, stroke, or myocardial infarction within 6 months of PCI...
December 5, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29223437/outcomes-in-elderly-and-young-patients-with-st-segment-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention-with-bivalirudin-versus-heparin-pooled-analysis-from-the-euromax-and-horizons-ami-trials
#3
Khalid Qaderdan, Gerrit-Jan A Vos, Thomas McAndrew, Philippe Gabriel Steg, Christian W Hamm, Arnoud Van't Hof, Roxana Mehran, Efthymios N Deliargyris, Debra Bernstein, Gregg W Stone, Jurriën M Ten Berg
BACKGROUND: Since older age is a strong predictor of not only bleeding but also of ischemic events, understanding the risk:benefit profile of bivalirudin in the elderly undergoing primary percutaneous coronary intervention (pPCI) for ST-segment elevation (STEMI) is important. For this, we aim to compare elderly with young patients, who all underwent pPCI for STEMI and randomly received either bivalirudin or heparin. METHODS: We performed a patient-level pooled analysis (n=5800) of two large randomized trials...
December 2017: American Heart Journal
https://www.readbyqxmd.com/read/29223432/contemporary-risk-model-for-inhospital-major-bleeding-for-patients-with-acute-myocardial-infarction-the-acute-coronary-treatment-and-intervention-outcomes-network-action-registry%C3%A2-get-with-the-guidelines-gwtg-%C3%A2
#4
Nihar R Desai, Kevin F Kennedy, David J Cohen, Traci Connolly, Deborah B Diercks, Mauro Moscucci, Stephen Ramee, John Spertus, Tracy Y Wang, Robert L McNamara
BACKGROUND: Major bleeding is a frequent complication for patients with acute myocardial infarction (AMI) and is associated with significant morbidity and mortality. OBJECTIVE: To develop a contemporary model for inhospital major bleeding that can both support clinical decision-making and serve as a foundation for assessing hospital quality. METHODS: An inhospital major bleeding model was developed using the Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With the Guidelines (ACTION Registry-GWTG) database...
December 2017: American Heart Journal
https://www.readbyqxmd.com/read/29223194/hospital-confirmed-acute-myocardial-infarction-prehospital-identification-using-the-medical-priority-dispatch-system
#5
Jeff J Clawson, Isabel Gardett, Greg Scott, Conrad Fivaz, Tracey Barron, Meghan Broadbent, Christopher Olola
Introduction Early recognition of an acute myocardial infarction (AMI) can increase the patient's likelihood of survival. As the first point of contact for patients accessing medical care through emergency services, emergency medical dispatchers (EMDs) represent the earliest potential identification point for AMIs. The objective of the study was to determine how AMI cases were coded and prioritized at the dispatch point, and also to describe the distribution of these cases by patient age and gender. Hypothesis/Problem No studies currently exist that describe the EMD's ability to correctly triage AMIs into Advanced Life Support (ALS) response tiers...
December 10, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29222628/one-year-clinical-effectiveness-comparison-of-prasugrel-with-ticagrelor-results-from-a-retrospective-observational-study-using-an-integrated-claims-database
#6
Mark B Effron, Kavita V Nair, Cliff Molife, Stuart Y Keller, Robert L Page, Jason C Simeone, Brian Murphy, Beth L Nordstrom, Yajun Zhu, Patrick L McCollam, George W Vetrovec
BACKGROUND: No direct comparisons of ticagrelor and prasugrel with 1-year clinical follow-up have been reported. OBJECTIVES: Our objective was to compare 1-year clinical outcomes among patients with acute coronary syndrome (ACS) managed with percutaneous coronary intervention (PCI) and treated with either ticagrelor or prasugrel in a real-world setting. METHODS: This retrospective study included patients from a payer database who were aged ≥18 years and had ACS managed with PCI with no history of transient ischemic attack (TIA)/stroke...
December 8, 2017: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/29222592/circadian-dependence-of-manual-thrombus-aspiration-benefit-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention
#7
Stephane Fournier, Olivier Muller, Umberto Benedetto, Marco Roffi, Thomas Pilgrim, Franz R Eberli, Hans Rickli, Dragana Radovanovic, Paul Erne, Stéphane Cook, Stéphane Noble, Rachel Fesselet, Andrea Zuffi, Sophie Degrauwe, PierGiorgio Masci, Stephan Windecker, Eric Eeckhout, Juan F Iglesias
BACKGROUND: The clinical benefit of manual thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction (STEMI) remains uncertain. This study assessed the impact of circadian rhythms on the effectiveness of manual TA. METHODS AND RESULTS: We conducted an observational study of patients enrolled in the Acute Myocardial Infarction in Switzerland Plus registry. STEMI patients undergoing PPCI with (TA group) or without (PCI-alone group) manual TA were divided based on time-of-day symptom onset: group 1 (00:00-05:59), group 2 (06:00-11:59), group 3 (12:00-17:59) and group 4 (18:00-23:59)...
December 8, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29222074/changes-of-oxygen-consumption-and-heart-rate-after-acute-myocardial-infarction-during-6-month-follow-up
#8
Yuri Choe, Jae-Young Han, In-Sung Choi, Hyeng-Kyu Park
BACKGROUND: Exercise intensity is a particularly important determinant of physiological responses to exercise training in patients with acute myocardial infarction. Heart rate (HR) is commonly used as a practical way of prescribing and monitoring exercise as specific intensities based on linear relationship between the percentage of maximum heart rate (%HRmax) and the percentage of maximum oxygen consumption (%VO2max) regardless of age, sex or exercise mode. OBJECTIVE: To examine the change in variability in the correlation between %HRmax and %VO2maxafter acute myocardial infarction...
December 5, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29221351/extracorporeal-membrane-oxygenation-system-as-a-bridge-to-reparative-surgery-in-ventricular-septal-defect-complicating-acute-inferoposterior-myocardial-infarction
#9
Jose Rozado, Isaac Pascual, Pablo Avanzas, Daniel Hernandez-Vaquero, Ruben Alvarez, Rocio Díaz, Beatriz Díaz, María Martín, Amelia Carro, Guillermo Muñiz, Jacobo Silva, Cesar Moris
Post-infarction ventricular septal defect (VSD) is a rare but potentially lethal complication of acute myocardial infarction. Medical management is usually futile, so definitive surgery remains the treatment of choice but the risk surgery is very high and the optimal timing for surgery is still under debate. A 55-year-old man with no previous medical history attended the emergency-room for 12 h evolution of oppressive chest pain and strong anginal pain 7 days ago. On physical examination, blood pressure was 96/70 mmHg, pansystolic murmur over left sternal border without pulmonary crackles...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221261/clinical-analysis-of-acute-myocardial-infarction-caused-by-coronary-embolism
#10
Zhen-Yu Jiao, Da-Peng Zhang, Kun Xia, Le-Feng Wang, Xin-Chun Yang
Background: This study aims to investigate the clinical and angiographic features in patients with acute myocardial infarction (AMI) induced by coronary artery embolism. Methods: Clinical data of five patients with AMI induced by coronary artery embolism were analyzed retrospectively. Results: One patient had left atrial myxoma, one patient had non-valvular atrial fibrillation, and three patients had rheumatic heart disease. Furthermore, one patient had mitral mechanical valve prostheses, two patients had atrial fibrillation...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29220755/coronary-artery-calcification-predicts-cardiovascular-complications-after-sepsis
#11
Vedant A Gupta, Matthew Sousa, Nathan Kraitman, Rahul Annabathula, Olga Vsevolozhskaya, Steve W Leung, Vincent L Sorrell
PURPOSE: Sepsis is a highly prevalent and fatal condition, with reported cardiovascular event rates as high as 25-30% at 1year. Risk stratification in septic patients has been extremely limited. MATERIAL AND METHODS: 267 septic patients with detectable troponin levels, APACHE II scores, and CT scans of the chest or abdomen were assessed. Patients with a recent cardiac intervention were excluded. Coronary artery calcification (CAC) was identified as present or absent on body CT scans...
December 2, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/29219272/-application-of-ima-and-h-fabp-in-forensic-diagnosis-of-sudden-cardiac-death
#12
REVIEW
Z L Zhu, P Wang, J B You, Q Yue, P F Wang, X L Wang, C N Zhang, G H Zhang
Acute myocardial ischemia is the most common cause of sudden cardiac death. The diagnosis of early myocardial ischemia is a hot point in forensic medicine, which is also an early and important part for a prevention against myocardial infarction. This paper conducts a comprehensive discussion of the structure, function, clinical value and forensic medicine application prospect of ischemia modified albumin (IMA) and heart-type fatty acid binding protein (H-FABP), aiming to determine whether the two proteins can be used as biochemical detection indicators of early myocardial ischemia for the diagnosis of sudden cardiac death in forensic medicine...
August 2017: Fa Yi Xue za Zhi
https://www.readbyqxmd.com/read/29219241/incidental-finding-of-arteria-lusoria-during-transradial-coronary-catheterization-significance-in-interventional-cardiology
#13
Arsalan Rafiq, Surendra Chutani, Nassim R Krim
Arteria lusoria is the most common anomaly of the aortic arch with an incidence of 0.5%-2.5%. It is mostly diagnosed incidentally while performing imaging for evaluation of other unrelated medical conditions. The aberrant right subclavian artery arises beyond the origin of the left subclavian artery from the aortic arch. This results in a complex right-subclavian-aortic anatomy which leads to difficulty in transradial coronary angiography. This can lead to prolonged procedure time and increased use of catheters by unaware interventionists...
December 8, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29218625/diuretic-or-beta-blocker-for-hypertensive-patients-already-receiving-acei-arb-and-calcium-channel-blocker
#14
Min-Shan Tsai, Chao-Hsiun Tang, Chia-Ying Lin, Po-Ya Chuang, Nai-Chuan Chen, Chien-Hua Huang, Wei-Tien Chang, Tzung-Dau Wang, Ping-Hsun Yu, Wen-Jone Chen
BACKGROUND: In patients already receiving combination of angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) and calcium channel blocker (CCB), whether the choice of additional diuretic or beta-blocker affects the cardiovascular and cerebrovascular outcomes remains unclear. METHODS: A total of 13,551 patients who were concurrently receiving three anti-hypertensive agents of different classes through outpatient clinics during 2004-2006 were identified from the National Health Insurance Research Database of Taiwan...
December 8, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29218093/p2x7-receptor-regulates-sympathoexcitatory-response-in-myocardial-infarction-rats-via-nf-%C3%AE%C2%BAb-and-mapk-pathways
#15
Qin Wu, Hongtao Xu, Ling Hao, Guifang Ma, Jinxia Sun, Xianghe Song, Fengyun Ding, Nan Wang
Previous studies have provided evidence for the regulatory effect of P2X7 receptor (P2X7R) on cardiovascular activities. Our study focused on exploring the function and fundamental mechanism of microglial P2X7R in controlling sympathoexcitatory response using rats with acute myocardial infarction (AMI). Coronary artery ligation was used in rats to cause AMI. And before that, rats were administrated with P2X7R siRNA that targeted P2X7R mRNA into paraventricular nucleus (PVN) or BBG (Brilliant Blue G, a P2X7 receptor antagonist)...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/29217002/the-delta-2-registry-a-multicenter-registry-evaluating-percutaneous-coronary-intervention-with-new-generation-drug-eluting-stents-in-patients-with-obstructive-left-main-coronary-artery-disease
#16
Alaide Chieffo, Akihito Tanaka, Gennaro Giustino, Ieva Briede, Fadi J Sawaya, Joost Daemen, Hiroyoshi Kawamoto, Emanuele Meliga, Fabrizio D'Ascenzo, Enrico Cerrato, Giulio G Stefanini, Davide Capodanno, Andrea Mangiameli, Christian Templin, Andrejs Erglis, Marie Claude Morice, Roxana Mehran, Nicolas M Van Mieghem, Sunao Nakamura, Mauro De Benedictis, Marco Pavani, Ferdinando Varbella, Marco Pisaniello, Samin K Sharma, Corrado Tamburino, Didier Tchetche, Antonio Colombo
OBJECTIVES: The aim of this study was to evaluate clinical outcomes of unprotected left main coronary artery percutaneous coronary intervention (PCI) with new-generation drug-eluting stents in a "real world" population. BACKGROUND: PCI of the unprotected left main coronary artery is currently recommended as an alternative to coronary artery bypass grafting (CABG) in selected patients. METHODS: All consecutive patients with unprotected left main coronary artery stenosis treated by PCI with second-generation drug-eluting stents were analyzed in this international, all-comers, multicenter registry...
December 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29216983/atrial-infarction-and-ischemic-mitral-regurgitation-contribute-to-post-mi-remodeling-of-the-left-atrium
#17
Jaume Aguero, Carlos Galan-Arriola, Rodrigo Fernandez-Jimenez, Javier Sanchez-Gonzalez, Nina Ajmone, Victoria Delgado, Jorge Solis, Gonzalo J Lopez, Antonio de Molina-Iracheta, Roger J Hajjar, Jeroen J Bax, Valentin Fuster, Borja Ibáñez
BACKGROUND: Left atrial (LA) remodeling after an acute myocardial infarction (MI) is poorly characterized regarding its determinants or its effect on ischemic mitral regurgitation (MR) development. OBJECTIVES: The purpose of this study was: 1) to compare LA structural remodeling in experimental MI swine models recapitulating the effects of left ventricular (LV) dysfunction, ischemic MR, and left atrial infarction (LAI); and 2) to analyze how LA remodeling influences ischemic MR development...
December 12, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29216666/-cardiac-rehabilitation
#18
Bernhard Schwaab
Physical training, psychosocial intervention, nutrition counselling and optimisation of secondary preventive medication to reduce morbidity and mortality of the disease as well as the reintegration into social life and return to work are equivalent goals of cardiac rehabilitation. This requires multifactorial intervention by a multidisciplinary team. In Germany, cardiac rehabilitation starting early after an index event could demonstrate a significant reduction of total mortality, myocardial infarction and hospitalisation during a follow-up of 1-2 years in 5 controlled cohort studies including 12 556 patients after myocardial infarction and CABG surgery...
December 7, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/29215835/-matrix-metalloproteinase-1-8-9-and-the-risk-of-cardiovascular-complications-in-patients-with-chd-before-and-after-myocardial-revascularization
#19
E V Shkorik, E V Markelova, A A Silaev, B I Geltser, A A Semenikhin, L N Fedjanina
There is still a great need for detection of biomarkers for early prediction and diagnosis of cardiovascular complications (CVC) in patients with CHD. Objective: To determine the role of MMP-1, 8, 9 in the risk of CCO in patients with CHD before and after coronary artery bypass grafting (CABG). Methods. The study included 75 patients with coronary heart disease before and after myocardial revascularization by CABG, including 40 men and 35 women aged from 45 to 74 years. Patients were divided into two groups: I group - 25 patients with CVC registered after CABG (acute myocardial infarction, ischemic stroke, pulmonary thromboembolism Branch); II group - 50 patients with coronary heart disease without complications after myocardial revascularization...
April 2017: Patologicheskaia Fiziologiia i èksperimental'naia Terapiia
https://www.readbyqxmd.com/read/29214816/left-ventricular-free-wall-rupture-after-surgery-for-ventricular-septal-rupture
#20
Tomoya Uchimuro, Motohiko Osako, Tetsuya Gotou, Toshiyuki Yamada, Ryogen Yoon
A 67-year-old man presented with late left ventricular free wall rupture 1 month after an extended sandwich technique through a right ventricular incision for ventricular septal rupture following an inferoposterior acute myocardial infarction. We found that residual infarcted myocardium had led to left ventricular aneurysm formation. A pericardial patch on the left ventricular side at the initial operation should have been secured further from the septal defect using a larger needle. A patch on the left ventricular side is important for complete exclusion of a free wall infarction and for decreasing the stress on the suture line securing the patch...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
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