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Mri, magnetic resonance, perfusion, diffusion, asl,

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https://www.readbyqxmd.com/read/27630562/cerebral-blood-flow-alterations-as-assessed-by-3d-asl-in-cognitive-impairment-in-patients-with-subcortical-vascular-cognitive-impairment-a-marker-for-disease-severity
#1
Yawen Sun, Wenwei Cao, Weina Ding, Yao Wang, Xu Han, Yan Zhou, Qun Xu, Yong Zhang, Jianrong Xu
Abnormal reductions in cortical cerebral blood flow (CBF) have been identified in subcortical vascular cognitive impairment (SVCI). However, little is known about the pattern of CBF reduction in relation with the degree of cognitive impairment. CBF measured with three-dimensional (3D) Arterial Spin Labeling (ASL) perfusion magnetic resonance imaging (MRI) helps detect functional changes in subjects with SVCI. We aimed to compare CBF maps in subcortical ischemic vascular disease (SIVD) subjects with and without cognitive impairment and to detect the relationship of the regions of CBF reduction in the brain with the degree of cognitive impairment according to the z-score...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27347052/application-of-3-0t-magnetic-resonance-arterial-spin-labeling-asl-technology-in-mild-and-moderate-intracranial-atherosclerotic-stenosis
#2
Zhongwei Li, Naikun Li, Yanyan Qu, Feng Gai, Guowei Zhang, Guanghui Zhang
The application value of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis was evaluated. A total of 58 cases of transient ischemic attack (TIA) and 60 cases of ischemic cerebral apoplexy cases were selected. The cases were analysed using a GE Healthcare Signa HDx 3.0T superconducting whole-body magnetic resonance scan within 24 h of attack. Eight-channel head phased array coils and conventional sequence were used to create T1-weighted images (T1WI), T2WI, diffusion-weighted imaging, magnetic resonance angiography (MRA) and ASL imaging, which were generated into ASL pseudo-color images (blue was hypoperfusion area) through post-processing in order to compare and analyze the correlation and differences between ASL and conventional imaging in terms of lesion location, size, blood perfusion situation and signal range of relative cerebral blood flow (rCBF)...
July 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27320876/-multi-parameter-arterial-spin-labeling-versus-dynamic-magnetic-sensitive-enhanced-cerebral-perfusion-imaging-for-diagnosis-of-transient-cerebral-ischemic-attack
#3
Yang Xu, Jin-Hao Lv, Lin Ma, Wei-Jun Chen, Xin Lou
OBJECTIVE: To evaluate the clinical value of three-dimensional pseudo-continuous arterial spin labeling (3D pCASL) perfusion magnetic resonance imaging (MRI) and dynamic susceptibility contrast (DSC) enhanced perfusion MRI in the diagnosis of transient ischemic attack (TIA). METHODS: Thirty-nine consecutive patients with suspected TIA underwent multi-modal MRI scans including DSC, magnetic resonance angiography (MRA), diffusion-weighted imaging (DWI) and 3D pCASL (post-labeling delay, PLD=1...
June 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/27209349/intratumor-heterogeneity-of-perfusion-and-diffusion-in-clear-cell-renal-cell-carcinoma-correlation-with-tumor-cellularity
#4
Qing Yuan, Payal Kapur, Yue Zhang, Yin Xi, Ingrid Carvo, Sabina Signoretti, Ivan E Dimitrov, Jeffrey A Cadeddu, Vitaly Margulis, James Brugarolas, Ananth J Madhuranthakam, Ivan Pedrosa
BACKGROUND: Magnetic resonance imaging (MRI) has the potential to noninvasively provide information about the tumor microenvironment. A correlation between arterial spin-labeled (ASL) MRI and tumor vasculature has been previously demonstrated; however, its correlation with tumor cellularity is unknown. We sought to assess intratumor heterogeneity of perfusion and diffusion in vivo in clear-cell renal cell carcinoma (ccRCC) using MRI and to correlate these findings with tumor vascularity and cellularity at histopathology...
December 2016: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/27113778/distinctive-patterns-of-three-dimensional-arterial-spin-labeled-perfusion-magnetic-resonance-imaging-in-subtypes-of-acute-ischemic-stroke
#5
Naoto Kohno, Kazunori Okada, Shingo Yamagata, Hiroyuki Takayoshi, Shuhei Yamaguchi
BACKGROUND: Ischemic penumbra in acute ischemic stroke (AIS) can be evaluated using arterial spin-labeled (ASL) perfusion magnetic resonance imaging (MRI). We used three-dimensional ASL-MRI to examine patients with different stroke subtypes and the clinical utility of the method within 24 hours of AIS onset. SUBJECTS AND METHODS: The 55 male and 48 female patients (mean age, 79.0 years) underwent diffusion-weighted imaging (DWI), fluid-attenuated inversion recovery imaging, magnetic resonance angiography, and pulsed continuous ASL perfusion imaging to determine stroke subtype, hypoperfused ASL area, and neurological deficit severity (National Institutes of Health Stroke Scale)...
July 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/25859832/state-of-the-art-mri-techniques-in-neuroradiology-principles-pitfalls-and-clinical-applications
#6
REVIEW
Magalie Viallon, Victor Cuvinciuc, Benedicte Delattre, Laura Merlini, Isabelle Barnaure-Nachbar, Seema Toso-Patel, Minerva Becker, Karl-Olof Lovblad, Sven Haller
This article reviews the most relevant state-of-the-art magnetic resonance (MR) techniques, which are clinically available to investigate brain diseases. MR acquisition techniques addressed include notably diffusion imaging (diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), and diffusion kurtosis imaging (DKI)) as well as perfusion imaging (dynamic susceptibility contrast (DSC), arterial spin labeling (ASL), and dynamic contrast enhanced (DCE)). The underlying models used to process these images are described, as well as the theoretic underpinnings of quantitative diffusion and perfusion MR imaging-based methods...
May 2015: Neuroradiology
https://www.readbyqxmd.com/read/25724245/nonconvulsive-partial-status-epilepticus-mimicking-recurrent-infarction-revealed-by-diffusion-weighted-and-arterial-spin-labeling-perfusion-magnetic-resonance-images
#7
Yuka Kanazawa, Takato Morioka, Shuji Arakawa, Yoshihiko Furuta, Asako Nakanishi, Takanari Kitazono
"Non-convulsive" partial status epilepticus (SE) is an important pathologic condition that should be differentiated from cerebral infarction. Herein, we reported 2 patients who had partial SE associated with old infarction in the right parietal lobe. Each patient had 2 episodes of left hemiparesis and hemisensory disturbance without convulsion. On diffusion-weighted magnetic resonance images (DW-MRI), a hyperintense lesion was noted in the cortex around the old infarction lesion, and recurrent infarction was suspected...
April 2015: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/25693668/caveat-of-measuring-perfusion-indexes-using-intravoxel-incoherent-motion-magnetic-resonance-imaging-in-the-human-brain
#8
Wen-Chau Wu, Ya-Fang Chen, Han-Min Tseng, Shun-Chung Yang, Pei-Chi My
OBJECTIVES: To numerically and experimentally investigate the robustness of intravoxel incoherent motion (IVIM) magnetic resonance imaging in measuring perfusion indexes in the human brain. METHODS: Eighteen healthy volunteers were imaged on a 3 T clinical system. Data of IVIM imaging (12 b-values ranging from 0 to 1000 s/mm(2), 12 repetitions) were fitted with a bi-exponential model to extract blood volume fraction (f) and pseudo-diffusion coefficient (D*). The robustness of measurement was assessed by bootstrapping...
August 2015: European Radiology
https://www.readbyqxmd.com/read/25263761/myocardial-perfusion-assessment-in-humans-using-steady-pulsed-arterial-spin-labeling
#9
Thibaut Capron, Thomas Troalen, Benjamin Robert, Alexis Jacquier, Monique Bernard, Frank Kober
PURPOSE: Although arterial spin labeling (ASL) has become a routinely performed method in the rodent heart, its application to the human heart remains challenged by low tissue blood flow and cardiac and respiratory motion. We hypothesized that an alternative steady-pulsed ASL (spASL) method would provide more efficient perfusion signal averaging by driving the tissue magnetization into a perfusion-dependent steady state. METHODS: We evaluated the feasibility of spASL in the human heart by combining pulsed labeling in the aortic root with a balanced steady state free precession sequence...
October 2015: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/25213753/lack-of-dystrophin-results-in-abnormal-cerebral-diffusion-and-perfusion-in-vivo
#10
Candida L Goodnough, Ying Gao, Xin Li, Mohammed Q Qutaish, L Henry Goodnough, Joseph Molter, David Wilson, Chris A Flask, Xin Yu
Dystrophin, the main component of the dystrophin-glycoprotein complex, plays an important role in maintaining the structural integrity of cells. It is also involved in the formation of the blood-brain barrier (BBB). To elucidate the impact of dystrophin disruption in vivo, we characterized changes in cerebral perfusion and diffusion in dystrophin-deficient mice (mdx) by magnetic resonance imaging (MRI). Arterial spin labeling (ASL) and diffusion-weighted MRI (DWI) studies were performed on 2-month-old and 10-month-old mdx mice and their age-matched wild-type controls (WT)...
November 15, 2014: NeuroImage
https://www.readbyqxmd.com/read/25002281/diffusion-tensor-magnetic-resonance-imaging-for-predicting-the-consistency-of-intracranial-meningiomas
#11
Rossana Romani, Wei-Jun Tang, Ying Mao, Dai-Jun Wang, Hai-Liang Tang, Feng-Ping Zhu, Xiao-Ming Che, Ye Gong, Kang Zheng, Ping Zhong, Shi-Qi Li, Wei-Min Bao, Christian Benner, Jing-Song Wu, Liang-Fu Zhou
BACKGROUND: The ability of preoperative MRI-sequences to predict the consistency of intracranial meningiomas has not yet been clearly defined. We aim to demonstrate that diffusion tensor imaging (DTI) improves the prediction of intracranial meningiomas consistency. METHODS: We prospectively studied 110 meningioma patients operated on in a single center from March 1st to the 25th of May 2012. Demographic data, location and size of the tumor, peritumoral edema, T1WI, T2WI, proton density weighted (PDWI), fluid-attenuated inversion recover (FLAIR) sequences, and arterial spin labeling (ASL) perfusion were studied and compared with the gray matter signal to predict meningioma consistency...
October 2014: Acta Neurochirurgica
https://www.readbyqxmd.com/read/24903554/the-role-of-magnetic-resonance-diffusion-weighted-imaging-and-three-dimensional-arterial-spin-labelling-perfusion-imaging-in-the-differentiation-of-parasellar-meningioma-and-cavernous-haemangioma
#12
Hua-Feng Xiao, Xin Lou, Meng-Yu Liu, Yu-Lin Wang, Yan Wang, Zhi-Ye Chen, Kai-Ning Shi, Lin Ma
OBJECTIVE: To evaluate the diagnostic value of magnetic resonance diffusion-weighted imaging (DWI) and three-dimensional arterial spin labelling perfusion imaging (3D-ASL) in distinguishing cavernous haemangioma from parasellar meningioma, using histological data as a reference standard. METHODS: Patients with parasellar meningioma or parasellar cavernous haemangioma underwent conventional T1- and T2-weighted magnetic resonance imaging (MRI) followed by DWI and 3D-ASL using a 3...
August 2014: Journal of International Medical Research
https://www.readbyqxmd.com/read/24507852/arterial-spin-labeling-magnetic-resonance-imaging-for-diagnosis-of-late-seizure-after-stroke
#13
Yosuke Miyaji, Mutsumi Yokoyama, Yuichi Kawabata, Hideto Joki, Yuji Kushi, Yasutaka Yokoi, Jo Sasame, Shunsuke Seki, Kentaro Mori, Tomoya Kamide, Akira Tamase, Hiroshi Shima, Motohiro Nomura, Yoshihisa Kitamura, Fumiaki Tanaka
BACKGROUND AND PURPOSE: Arterial spin labeling (ASL) is a non-invasive modality of magnetic resonance imaging (MRI) used to evaluate cerebral perfusion without a contrast agent. The usefulness of ASL for diagnosis in the acute phase of late seizure after stroke was evaluated. METHODS: Twelve consecutive patients diagnosed with late seizure after stroke were enrolled in this study. MRI including ASL was performed for each patient at the time of the emergency department visit...
April 15, 2014: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/24302482/arterial-spin-labeling-versus-bolus-tracking-perfusion-in-hyperacute-stroke
#14
COMPARATIVE STUDY
Andrew Bivard, Venkatesh Krishnamurthy, Peter Stanwell, Christopher Levi, Neil J Spratt, Stephen Davis, Mark Parsons
BACKGROUND AND PURPOSE: Arterial spin labeling (ASL) is a perfusion magnetic resonance imaging (MRI) technique that does not require contrast administration and thus may be more practical in hyperacute stroke than susceptibility-weighted bolus-tracking perfusion-weighted imaging (PWI). However, a threshold for ASL measurement of the ischemic penumbra needs to be determined. METHODS: A total of 58 patients with acute hemispheric ischemic stroke were imaged within 6 hours of symptom onset with MRI including ASL, diffusion-weighted MRI (DWI), and PWI, after perfusion computed tomography (CTP)...
January 2014: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/23252679/imaging-of-intrarenal-haemodynamics-and-oxygen-metabolism
#15
REVIEW
Per Liss, Eleanor F Cox, Per Eckerbom, Sue T Francis
The interruption of blood flow results in impaired oxygenation and metabolism. This can lead to electrophysiological changes, functional impairment and symptoms in quick succession. Quantitative measures of organ perfusion, perfusion reserve and tissue oxygenation are crucial to assess normal tissue metabolism and function. Magnetic resonance imaging (MRI) provides a number of quantitative methods to assess physiology in the kidney. Blood oxygenation level-dependent (BOLD) MRI provides a method for the assessment of oxygenation...
February 2013: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/22832118/changes-in-cerebral-blood-flow-after-transjugular-intrahepatic-portosystemic-shunt-can-help-predict-the-development-of-hepatic-encephalopathy-an-arterial-spin-labeling-mr-study
#16
Gang Zheng, Long Jiang Zhang, Ze Wang, Rong Feng Qi, Donghong Shi, Li Wang, Xinxin Fan, Guang Ming Lu
BACKGROUND AND PURPOSE: Cerebral blood flow (CBF) changes after transjugular intrahepatic portosystemic shunt (TIPS) are still unclear. Our aim is to assess the TIPS-induced CBF changes and their potential clinical significance using the arterial spin labeling (ASL) perfusion magnetic resonance imaging. MATERIALS AND METHODS: Nine cirrhotic patients underwent ASL 1-8 days before and 4-7 days after TIPS. CBF was calculated at each voxel and mean CBF values were computed in the whole brain, gray matter and white matter...
December 2012: European Journal of Radiology
https://www.readbyqxmd.com/read/22539548/comparison-of-arterial-spin-labeling-and-bolus-perfusion-weighted-imaging-for-detecting-mismatch-in-acute-stroke
#17
COMPARATIVE STUDY
Greg Zaharchuk, Ibraheem S El Mogy, Nancy J Fischbein, Gregory W Albers
BACKGROUND AND PURPOSE: The perfusion-weighted imaging (PWI)-diffusion-weighted imaging (DWI) mismatch paradigm is widely used in stroke imaging studies. Arterial spin labeling (ASL) is an alternative perfusion method that does not require contrast. This study compares the agreement of ASL-DWI and PWI-DWI mismatch classification in patients with stroke. METHODS: This was a retrospective study drawn from all 1.5-T MRI studies performed in 2010 at a single institution...
July 2012: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/22426319/whole-brain-arterial-spin-labeling-perfusion-mri-in-patients-with-acute-stroke
#18
COMPARATIVE STUDY
Reinoud P H Bokkers, Daymara A Hernandez, José G Merino, Raymond V Mirasol, Matthias J van Osch, Jeroen Hendrikse, Steven Warach, Lawrence L Latour
BACKGROUND AND PURPOSE: Perfusion MRI can be used to identify patients with acute ischemic stroke who may benefit from reperfusion therapies. The risk of nephrogenic systemic fibrosis, however, limits the use of contrast agents. Our objective was to evaluate the ability of arterial spin labeling (ASL), an alternative noninvasive perfusion technique, to detect perfusion deficits compared with dynamic susceptibility contrast (DSC) perfusion imaging. METHODS: Consecutive patients referred for emergency assessment of suspected acute stroke within a 7-month period were imaged with both ASL and DSC perfusion MRI...
May 2012: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/22343640/pseudocontinuous-arterial-spin-labeling-quantifies-relative-cerebral-blood-flow-in-acute-stroke
#19
Daymara A Hernandez, Reinoud P H Bokkers, Raymond V Mirasol, Marie Luby, Erica C Henning, José G Merino, Steven Warach, Lawrence L Latour
BACKGROUND AND PURPOSE: The aim of this study was to test whether arterial spin labeling (ASL) can detect significant differences in relative cerebral blood flow (rCBF) in the core, mismatch, and reverse-mismatch regions, and whether rCBF values measured by ASL in those areas differ from values obtained using dynamic susceptibility contrast (DSC) MRI. METHODS: Acute stroke patients were imaged with diffusion-weighted imaging (DWI) and perfusion-weighted imaging (ASL and DSC) MRI...
March 2012: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/22245338/early-development-of-arterial-spin-labeling-to-measure-regional-brain-blood-flow-by-mri
#20
REVIEW
Alan P Koretsky
Two major avenues of work converged in the late 1980's and early 1990's to give rise to brain perfusion MRI. The development of anatomical brain MRI quickly had as a major goal the generation of angiograms using tricks to label flowing blood in macroscopic vessels. These ideas were aimed at getting information about microcirculatory flow as well. Over the same time course the development of in vivo magnetic resonance spectroscopy had as its primary goal the assessment of tissue function and in particular, tissue energetics...
August 15, 2012: NeuroImage
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