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Amniotic fluid ultrasound

Susanna Holmlund, Tommi Kauko, Jaakko Matomäki, Miia Tuominen, Juha Mäkinen, Päivi Rautava
BACKGROUND: To date, several studies concerning the effects of induced abortion (IA) on women's later psychosocial well-being and future delivery complications have been published. However, the lack of reports on woman's physical well-being during their first full-term pregnancy occurring after IA is what inspired the current study. Here, we evaluate the physical well-being and use of maternity services of first-time mothers with a history of IA. METHODS: Finnish National Birth Registry data from 2008 to 2010 were linked with the Induced Abortion Registry data from 1983 to 2007...
October 24, 2016: BMC Pregnancy and Childbirth
Dawn S Hughes, Everett F Magann
The evaluation of amniotic fluid volume (AFV) is an established part of the antenatal surveillance of pregnancies at risk for an adverse pregnancy outcome. The two most commonly used ultrasound techniques to estimate AFV are the amniotic fluid index (AFI) and the single deepest pocket (SDP). Four studies have defined normal AFVs, and although their normal volumes have similarities, there are also differences primarily due to the statistical methodology used in each study. Dye-determined AFV correlates with ultrasound estimates for normal fluid volumes but correlates poorly for oligohydramnios and polyhydramnios...
September 16, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
Mariya Angelova, Emil Kovachev, Nikolai Todorov
AIM: The aim of this publication is to present a case of CMV infection during pregnancy, with clinical manifestations of the development of microcephaly and simultaneous dilatation of the 3rd and 4th brain ventricle at 23 weeks gestation. This article discusses the role of ultrasound screening in the second trimester of pregnancy. CASE PRESENTATION: We present the case of a 25-year-old woman with the initials S.K. in her second pregnancy that came to our antenatal Consulting Centre...
September 15, 2016: Open Access Macedonian Journal of Medical Sciences
Jorge Andrés Carvajal, Fernando Andrés Ferrer, Francisca Isabel Araya, Ana María Delpiano
INTRODUCTION: Brain natriuretic peptide (BNP) is synthesized by human fetal membranes, both the amnion and chorion. This locally produced BNP inhibits the contraction of the human myometrium, contributing to the maintenance of myometrial quiescence during pregnancy. Reference values for NT-proBNP concentrations in amniotic fluid at different gestational ages have not been completely defined. We aimed to investigate the range of fetal NT-proBNP values in amniotic fluid in normal pregnancy between 17 and 41weeks of gestation...
September 7, 2016: Clinical Biochemistry
Nicola Persico, Alfredo Berettini, Isabella Fabietti, Chiara Dallagiovanna, Dario Minoli, Fabio Mosca, Luigi Fedele, Gianantonio Manzoni
Prenatal ultrasound detection of fetal ureterocele with bilateral hydro-ureteronephrosis, obstruction of the bladder outlet and progressive amniotic fluid reduction can be associated with a significant risk of end-stage chronic renal disease after birth. Fetal cystoscopic laser incision of the ureterocele, with the aim of relieving the bladder outflow obstruction to preserve renal function, has been previously reported in one case, with a favourable outcome. This report employed standard 3.5-mm fetoscopic access to the amniotic cavity and the fetal bladder...
September 8, 2016: Ultrasound in Obstetrics & Gynecology
Maurizio Zavattoni, Stefano Paolucci, Antonella Sarasini, Beatrice Tassis, Mariangela Rustico, Aida Quarenghi, Antonio Piralla, Fausto Baldanti
To define diagnostic and prognostic markers of parvovirus B19 (B19V) fetal infection, two groups were investigated: 1) pregnant women with specific symptoms or contacts with symptomatic households (n=37); 2) mothers with pathological ultrasound findings and the relevant fetus at the time of prenatal diagnosis (n=16). In the first group, diagnosis of B19V infection was achieved using IgM detection in 29/37 (78.3%) of patients, while B19V DNA was detected in 36/37 (97.3%) of infected women. In the second group, intrauterine infection was investigated by amniocentesis (n=5), cordocentesis (n=3) or both (n=5)...
September 2016: New Microbiologica
Hatice Akkaya, Barış Büke, Meryem Kuru Pekcan, Kıvanç Şahin, Gülsüm Uysal, Gülin Feykan Yeğin, Ayşe Filiz Avşar, Fulya Çağlı
OBJECTIVE: To evaluate the relationship between entanglement of umbilical cord around the fetal neck and adverse perinatal outcomes. METHODS: In this prospective cohort study, perinatal outcomes of 218 pregnancies complicated with nuchal cord (NC) (study group) were compared with 190 uncomplicated pregnancies (control group). Main outcome measures were umbilical cord pH values, APGAR scores and cesarean section (C/S) rates. Fetal distress was stated as an abnormal heart rate pattern on electronic fetal heart monitorization...
September 1, 2016: Journal of Maternal-fetal & Neonatal Medicine
Maria Gańczak, Agnieszka Brodowska
Zika virus (ZIKAV) infections could potentially occur in Poland due to international travel made by its nationals to regions where the Aedes mosquito is active. A causal relationship between prenatal ZIKAV infection and microcephaly and other serious brain anomalies has been found due to the time association between the infection in pregnancy and a presence of congenital nervous system malformations, together with the detectable pathogen in amniotic fluid and fetus's tissues. Two ZIKAV infection cases of pregnant women who were diagnosed with fetal microcephaly in the state of Paraiba, Brazil, later described in Ultrasound Obstetrics and Gynecology by Oliveira Mello et al...
2016: Ginekologia Polska
Alberto Borges Peixoto, Taciana Mara Rodrigues da Cunha Caldas, Tácito Augusto Godoy Silva, Mário Sérgio Silva Gomes Caetano, Wellington P Martins, Eduardo Felix Martins Santana, Edward Araujo Júnior
OBJECTIVES: The aim of the study was to investigate ultrasound and Doppler parameters in the third trimester of pregnancy as possible predictors of adverse perinatal outcome in unselected pregnancies. MATERIAL AND METHODS: We performed a retrospective cross-sectional study including unselected pregnant women be-tween 27 and 36 + 6 weeks of gestation. The following ultrasound and Doppler parameters were assessed: estimated fetal weight (EFW) [g], EFW percentile, placental maturity grade (Grannum classification), single vertical deepest pocket (SVDP) of amniotic fluid [cm], amniotic fluid index (AFI) [cm], mean uterine artery (UtA) pulsatility index (PI), umbilical artery (UA) PI, middle cerebral artery (MCA) PI, MCA peak systolic velocity (PSV) [cm/s], and cerebroplacental ratio (CPR)...
2016: Ginekologia Polska
Maurizio Zavattoni, Stefano Paolucci, Antonella Sarasini, Beatrice Tassis, Mariangela Rustico, Aida Quarenghi, Antonio Piralla, Fausto Baldanti
To define diagnostic and prognostic markers of parvovirus B19 (B19V) fetal infection, two groups were investigated: 1) pregnant women with specific symptoms or contacts with symptomatic households (n=37); 2) mothers with pathological ultrasound findings and the relevant fetus at the time of prenatal diagnosis (n=16). In the first group, diagnosis of B19V infection was achieved using IgM detection in 29/37 (78.3%) of patients, while B19V DNA was detected in 36/37 (97.3%) of infected women. In the second group, intrauterine infection was investigated by amniocentesis (n=5), cordocentesis (n=3) or both (n=5)...
July 2016: New Microbiologica
Warwick B Dunn, J William Allwood, Tim Van Mieghem, R Katie Morris, Fiona L Mackie, Caroline E Fox, Mark D Kilby
INTRODUCTION: Twin-twin transfusion syndrome (TTTS) complicates 15% of monochorionic twin pregnancies, often being associated with recipient cardiac dysfunction. Untreated, it has a fetal mortality rate of at least 90%; although treatment by fetoscopic laser coagulation significantly improves prognosis. Measurement of recipient amniotic fluid metabolites, such as cardiac Troponin T and atrial natriuretic polypeptide, correlate with cardiac function in this fetus. The aim of this study is to describe the amniotic fluid metabolomic profile in TTTS, relate this to fetal recipient cardiac function and assess the metabolomic changes induced by fetoscopic laser coagulation...
August 2016: Placenta
Shan Dan, Yuan Yuan, Yaoshen Wang, Chao Chen, Changxin Gao, Song Yu, Yan Liu, Wei Song, Asan, Hongmei Zhu, Ling Yang, Hongmei Deng, Yue Su, Xin Yi
BACKGROUND: Since the discovery of cell-free foetal DNA in the plasma of pregnant women, many non-invasive prenatal testing assays have been developed. In the area of skeletal dysplasia diagnosis, some PCR-based non-invasive prenatal testing assays have been developed to facilitate the ultrasound diagnosis of skeletal dysplasias that are caused by de novo mutations. However, skeletal dysplasias are a group of heterogeneous genetic diseases, the PCR-based method is hard to detect multiple gene or loci simultaneously, and the diagnosis rate is highly dependent on the accuracy of the ultrasound diagnosis...
2016: PloS One
Sonia Perez, Ruben Tato, Jorge Julio Cabrera, Alberto Lopez, Olga Robles, Eugenio Paz, Amparo Coira, Maria Paz Sanchez-Seco, Ana Vazquez, Raquel Carballo, Carlos Quintas, Anxela Pousa
We describe Zika virus (ZIKV) vertical transmission in an imported case in Spain, in a 17-week pregnant woman. ZIKV IgG, IgM and RNA were detected in serum in week 17. At 19 weeks, ultrasound scan revealed fetal malformations and ZIKV was detected in the amniotic fluid. Pregnancy was terminated at week 21; autopsy of the fetus revealed bilateral hydrocephalus, brain microcalcifications and arthrogryposis multiplex congenita. ZIKV was detected in the umbilical cord and brain tissue.
June 16, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
Ayşegül Altunkeser, Muslu Kazım Körez
OBJECTIVES: Ramadan is a holy month in which eating and drinking are forbidden from dawn to sunset. In this study, we investigated using ultrasonography (USG) whether fasting in summer (as occurred in Ramadan 2014) had an influence on the volume of amniotic fluid during pregnancy. MATERIALS AND METHODS: The study included 119 pregnant women in total who were admitted to our department with a request of obstetric USG between June 28, 2014, and July 27, 2014. The fasting group included 61 pregnant women and the control group of 58 pregnant women...
2016: Journal of Clinical Imaging Science
Alex Sandro Rolland Souza, Adriane Farias Patriota, Gláucia Virgínia de Queiroz Lins Guerra, Brena Carvalho Pinto de Melo
OBJECTIVE: To determine the association between amniotic fluid index (AFI) and perinatal outcomes in preterm premature rupture of membranes (PPROM). METHOD: A retrospective cohort study was conducted between 2008 and 2012. 86 pregnant women were included, with a diagnosis of PPROM and gestational age from 24 to 35 weeks. Women who presented hypertensive disorders, diabetes, fetuses with birth defects and infection at admission were excluded. To determine the association between AFI and perinatal outcomes, chi-square and Fisher's exact test were used if necessary, as well as risk ratio (RR) and 95% confidence intervals (95CI)...
May 2016: Revista da Associação Médica Brasileira
L Jayyosi, N Boudaoud, O Okiemy, N Correia, E Alanio-Detton, J P Bory, A Liné, M L Poli-Merol, S Mazouz Dorval, C Francois
The umbilicus is our first scar. It is the last remain of our life in utero. Besides the umbilical hernia, a common pathology during the first three years of life that rarely requires surgery, there are some rare congenital abnormalities such as gastroschisis and omphalocele, which occur in about 1-5/10,000 births. Gastroschisis is a birth defect of the anterior abdominal wall, through which the fetal intestines freely protrude and are not covered by any membranes. During the 13th week prenatal ultrasound, the umbilical cord can be seen to be properly attached while the intestines float freely in the amniotic fluid...
June 8, 2016: Annales de Chirurgie Plastique et Esthétique
Simona Boito, Francesca Crovetto, Benedetta Ischia, Beatrice Letizia Crippa, Isabella Fabietti, Maria Francesca Bedeschi, Faustina Lalatta, Lorenzo Colombo, Fabio Mosca, Luigi Fedele, Nicola Persico
OBJECTIVE: The objective of the study is to examine the incidence of chromosomal or genetic abnormalities in pregnancies complicated by polyhydramnios and to assess the value of prenatal ultrasound findings in the prediction of cases associated with such disorders. METHODS: We searched the prenatal records of all patients delivered in our hospital with a diagnosis of polyhydramnios during pregnancy. For each case, maternal characteristics, ultrasound findings, and genetic testing results were recorded...
August 2016: Prenatal Diagnosis
Sarah J Stock, Olga Patey, Basky Thilaganathan, Scott White, Lucy L Furfaro, Matthew S Payne, Owen B Spiller, Andres Noé, Rory Watts, Sean Carter, Demelza J Ireland, Alan H Jobe, John P Newnham, Matthew W Kemp
INTRODUCTION: Several recent studies have identified a potential role for intrauterine Candida albicans in adverse pregnancy outcomes, including preterm birth. There is, however, a limited understanding of the impact of intrauterine candida infection on fetal well-being in early pregnancy. Using a sheep model of early pregnancy, the aims of this study were to determine (1) the ability of experimentally induced intrauterine C albicans to infect the fetus and (2) whether C albicans exposure in early pregnancy is associated with alterations in fetal cardiac function, as measured by spectral tissue Doppler imaging analysis of fetal cardiac function...
May 23, 2016: Reproductive Sciences
Emmanuel Spaggiari, Giuliana Faure, Sophie Dreux, Isabelle Czerkiewicz, Julien J Stirnemann, Fabien Guimiot, Laurence Heidet, Romain Favre, Laurent J Salomon, Jean François Oury, Yves Ville, Francoise Muller
OBJECTIVES: Fetal serum β2-microglobulin has been shown to predict postnatal renal outcome in fetal obstructive uropathy. We assessed the value of sequential sampling for fetal serum β2-microglobulin in the prediction of postnatal renal outcome. METHODS: We retrospectively studied renal outcome in 42 fetuses with bilateral or low obstructive urinary tract obstruction for whom fetal blood was sampled on at least two occasions to assay β2-microglobulin in fetal serum...
May 20, 2016: Ultrasound in Obstetrics & Gynecology
Ratna Dua Puri, Udhaya Kotecha, Meena Lall, Pratima Dash, Sunita Bijarnia-Mahay, Ishwar Chander Verma
The utility of fetal autopsy to corroborate antenatal ultrasound findings and to aid genetic counseling is well known. However, the ability to identify an underlying cause for the common indications for which it is performed is not well studied. This study aimed to determine if the diagnostic yield of fetal autopsy in identifying the underlying cause is determined by the indication of the autopsy. Five groups of fetuses were defined based on the indication for the autopsy performed in 903 cases: (i) malformations, (ii) intrauterine death (IUD), (iii) cystic hygroma and hydrops fetalis, (iv) isolated abnormalities of amniotic fluid, and (v) intrauterine growth restriction (IUGR)...
August 2016: American Journal of Medical Genetics. Part A
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