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https://www.readbyqxmd.com/read/28294090/evaluation-of-staphylococcus-aureus-bacteremia-academic-and-community-based-management-within-the-same-health-system
#1
Sumaya Ased, Hamza Rayes, Jaspreet Dhami, Nick Amosson, Akua Fordjour, Jeff Macaraeg, Renuga Vivekanandan, Josh Wilson, Annie Cabri, Michele Davids, Jennifer Anthone, Stephen Cavalieri, Christopher J Destache
A nonrandomized, retrospective comparison of Staphylococcus aureus bacteremia between an academic hospital setting (n=53) and a community hospital setting (n=245) within a single healthcare system was performed. Despite infectious disease consultations, S. aureus bacteremia management recommendations based on Infectious Diseases Society of America (IDSA) guidelines were not followed as closely in the community hospital setting. The community hospital setting requires management standardization for patients with S...
March 15, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28115504/lack-of-adherence-to-shea-idsa-treatment-guidelines-for-clostridium-difficile-infection-is-associated-with-increased-mortality
#2
I Patel, M Wungjiranirun, T Theethira, J Villafuerte-Galvez, N Castillo, M Akbari, C D Alonso, D A Leffler, C P Kelly
OBJECTIVES: The objective of this study was to determine our institution's compliance with 2010 Society for Healthcare Epidemiology of America and IDSA Clostridium difficile infection (CDI) treatment guidelines and their respective outcomes. METHODS: We collected clinical parameters, laboratory values, antibiotic therapy and clinical outcomes from the electronic medical records for all patients hospitalized at our institution with a diagnosis of CDI from December 2012 to November 2013...
February 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28114875/catheter-associated-urinary-tract-infection-cauti-after-term-cesarean-delivery-incidence-and-risk-factors-at-a-multi-center-academic-institution
#3
Laura Moulton, Mark Lachiewicz, Xiaobo Liu, Oluwatosin Goje
PURPOSE: The purpose of this study is to identify the rate of catheter-associated urinary tract infection (CAUTI) after Cesarean delivery (CD) and to determine if any factors increase risk of infection. METHODS: A retrospective cohort study was performed at a multi-center institution for patients who underwent CD in 2013. All patients had urinary catheters inserted before surgery. Diagnosis followed IDSA guidelines with culture growing greater than 10(3) CFU of bacteria per mL with symptoms or symptomatic urinary tract infections treated at provider discretion...
February 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28011960/visceral-leishmaniasis-in-immunocompromised-diagnostic-and-therapeutic-approach-and-evaluation-of-the-recently-released-idsa-guidelines
#4
Pasquale Pagliano, Tiziana Ascione, Giusy Di Flumeri, Giovanni Boccia, Francesco De Caro
Visceral Leishmaniasis (VL) is a chronic infectious disease endemic in tropical and sub-tropical areas including the Mediterranean basin, caused by a group of protozoan parasites of the genus Leishmania and transmitted by phlebotomine sandflies. Typically, VL is classified as a zoonotic infection when Leishmania infantum is the causative agent and as an anthroponotic one when L. donovani is the causative agent. Immunocompromised patients, in particular HIV positive, are considered at risk of VL. They may present atypical signs and poor response to the treatment due to a compromission of T-helper and regulatory cells activity...
December 1, 2016: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/27941151/diagnosis-and-treatment-of-leishmaniasis-clinical-practice-guidelines-by-the-infectious-diseases-society-of-america-idsa-and-the-american-society-of-tropical-medicine-and-hygiene-astmh
#5
Naomi Aronson, Barbara L Herwaldt, Michael Libman, Richard Pearson, Rogelio Lopez-Velez, Peter Weina, Edgar M Carvalho, Moshe Ephros, Selma Jeronimo, Alan Magill
It is important to realize that leishmaniasis guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. The IDSA and ASTMH consider adherence to these guidelines to be voluntary, with the ultimate determinations regarding their application to be made by the physician in the light of each patient's individual circumstances.
December 15, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27941143/diagnosis-and-treatment-of-leishmaniasis-clinical-practice-guidelines-by-the-infectious-diseases-society-of-america-idsa-and-the-american-society-of-tropical-medicine-and-hygiene-astmh
#6
Naomi Aronson, Barbara L Herwaldt, Michael Libman, Richard Pearson, Rogelio Lopez-Velez, Peter Weina, Edgar M Carvalho, Moshe Ephros, Selma Jeronimo, Alan Magill
It is important to realize that leishmaniasis guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. The IDSA and ASTMH consider adherence to these guidelines to be voluntary, with the ultimate determinations regarding their application to be made by the physician in the light of each patient's individual circumstances.
December 15, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27927991/diagnosis-and-treatment-of-leishmaniasis-clinical-practice-guidelines-by-the-infectious-diseases-society-of-america-idsa-and-the-american-society-of-tropical-medicine-and-hygiene-astmh
#7
Naomi Aronson, Barbara L Herwaldt, Michael Libman, Richard Pearson, Rogelio Lopez-Velez, Peter Weina, Edgar Carvalho, Moshe Ephros, Selma Jeronimo, Alan Magill
No abstract text is available yet for this article.
January 11, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27927865/impact-of-infectious-diseases-consultation-on-mortality-of-cryptococcal-infection-in-patients-without-hiv
#8
Andrej Spec, Margaret A Olsen, Krunal Raval, William G Powderly
BACKGROUND: An infectious disease (ID) consultation is often obtained to treat patients with cryptococcosis due to the complex nature of the disease, but has never been demonstrated to impact outcomes. METHODS: We assembled a retrospective cohort of 147 consecutive cases of cryptococcosis in patients without HIV. Patients who were diagnosed less than 24 hours prior to death were excluded. Survival analysis was performed with Cox regression with survival censored past 90 days...
December 7, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27915306/a-consort-analysis-of-randomised-controlled-trials-for-the-treatment-of-invasive-aspergillosis
#9
Brian L Jones, Malcolm D Richardson, Patricia M Ingram, Samir G Agrawal
There is no assessment of the reporting quality of antifungal randomized, controlled trials (RCT), upon which guidelines for the treatment of invasive aspergillosis (IA) in patients with hematological malignancy are based. Trial reports were identified through Trip, Cochrane, Medline, and Embase database searches. Report quality was assessed using the 25-item CONSORT checklist and a rating scale of 1 (strongly disagree) to 4 (strongly agree). The primary endpoint was quality as assessed by mean group-scores among papers published at the time of the most recent IA treatment guidelines...
December 3, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27910139/characterization-of-patients-with-chronic-pulmonary-aspergillosis-according-to-the-new-escmid-ers-ecmm-and-idsa-guidelines
#10
COMPARATIVE STUDY
Helmut J F Salzer, Jan Heyckendorf, Barbara Kalsdorf, Thierry Rolling, Christoph Lange
Recently, the Infectious Diseases Society of America (IDSA) and the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) in cooperation with the European Respiratory Society (ERS) and the European Confederation of Medical Mycology (ECMM) published guidelines for the diagnosis of chronic pulmonary aspergillosis (CPA). Both guidelines, however, carry significant differences. We retrospectively applied the diagnostic recommendations on a patient cohort of 71 previously diagnosed CPA patients in order to compare both guidelines...
February 2017: Mycoses
https://www.readbyqxmd.com/read/27852357/a-multifaceted-approach-to-reduction-of-catheter-associated-urinary-tract-infections-in-the-intensive-care-unit-with-an-emphasis-on-stewardship-of-culturing
#11
Katherine M Mullin, Christopher S Kovacs, Cynthia Fatica, Colette Einloth, Elizabeth A Neuner, Jorge A Guzman, Eric Kaiser, Venu Menon, Leticia Castillo, Marc J Popovich, Edward M Manno, Steven M Gordon, Thomas G Fraser
BACKGROUND Catheter-associated urinary tract infections (CAUTIs) are among the most common hospital-acquired infections (HAIs). Reducing CAUTI rates has become a major focus of attention due to increasing public health concerns and reimbursement implications. OBJECTIVE To implement and describe a multifaceted intervention to decrease CAUTIs in our ICUs with an emphasis on indications for obtaining a urine culture. METHODS A project team composed of all critical care disciplines was assembled to address an institutional goal of decreasing CAUTIs...
February 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27836315/elderly-patients-are-at-increased-risk-for-treatment-failure-in-outpatient-management-of-purulent-skin-infections
#12
John P Haran, Eric Wilsterman, Tyler Zeoli, Francesca L Beaudoin, Jennifer Tjia, Patricia L Hibberd
OBJECTIVE: Current Infectious Disease Society of America (IDSA) guidelines for the management of purulent skin or soft tissue infections do not account for patient age in treatment recommendations. The study objective was to determine if age was associated with outpatient treatment failure for purulent skin infection after adjusting for IDSA treatment guidelines. METHODS: We conducted a multicenter retrospective study of adult patients treated for a purulent skin infection and discharged home from four emergency departments between April and September 2014...
February 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27820708/lyme-neuroborreliosis
#13
Uwe Koedel, Hans-Walter Pfister
PURPOSE OF REVIEW: Lyme disease is a multistage and multisystem disease. Neurological manifestations [termed Lyme neuroborreliosis (LNB)] occur in about 10% of patients with Lyme disease. Diagnostics and treatment of early and late LNB are widely established. However, the management of persistent symptoms is still fraught with controversies, and therefore is the focus of this review. RECENT FINDINGS: The incidence of Lyme disease seems to be much higher than previously assumed...
February 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/27817806/factors-which-influence-treatment-initiation-for-pulmonary-non-tuberculous-mycobacterium-infection-in-hiv-negative-patients-a-multicentre-observational-study
#14
Timothy M Rawson, Aula Abbara, Katharina Kranzer, Andrew Ritchie, James Milburn, Tim Brown, David Adeboyeku, Jim Buckley, Robert N Davidson, Matthew Berry, Onn Min Kon, Laurence John
BACKGROUND: Clinical, radiological and microbiological criteria inform diagnosis of pulmonary Non-Tuberculous Mycobacteria (NTM) disease and treatment decisions. This multicentre, review aims to characterise NTM disease meeting ATS/IDSA criteria and define factors associated with initiation of treatment. METHODS: Sputum samples growing NTM from 5 London hospitals between 2010 and 2014 were identified. Data for HIV-negative individuals meeting ATS/IDSA guidelines for pulmonary NTM disease were extracted...
November 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27815108/evaluation-and-management-of-the-nursing-home-resident-with-respiratory-symptoms-and-an-equivocal-chest-x-ray-report
#15
Mallory McClester Brown, Philip D Sloane, Christine E Kistler, David Reed, Kimberly Ward, David Weber, Sheryl Zimmerman
OBJECTIVES: Pneumonia is a leading cause of morbidity and mortality in nursing home (NH) residents. Chest x-ray evidence is considered a key diagnostic criterion for pneumonia by the Infectious Disease Society of America (IDSA) diagnostic guidelines, the modified McGeer diagnostic criteria, and the Loeb criteria for initiating antibiotics; however, x-ray interpretation is often equivocal. We conducted chart audits of patients in NHs who had chest x-rays for new respiratory symptoms to determine the degree of ambiguity in the radiology reports and their relationship to antibiotic prescription decisions...
December 1, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27804902/non-tuberculous-mycobacteria-epidemiological-pattern-in-a-reference-laboratory-and-risk-factors-associated-with-pulmonary-disease
#16
J Mencarini, C Cresci, M T Simonetti, C Truppa, G Camiciottoli, M L Frilli, P G Rogasi, S Veloci, M Pistolesi, G M Rossolini, A Bartoloni, F Bartalesi
The diseases caused by non-tuberculous mycobacteria (NTM), in both AIDS and non-AIDS populations, are increasingly recognized worldwide. Although the American Thoracic Society published the guidelines for diagnosis of NTM pulmonary disease (NTM-PD), the diagnosis is still difficult. In the first part of the study, we collected data on NTM isolates in the Mycobacteriology Laboratory of Careggi Hospital (Florence, Italy) and analysed the epidemiological data of NTM isolates. Then, to analyse the risk factors associated to NTM-PD, we studied the presence of ATS/IDSA criteria for NTM-PD in patients who had at least one positive respiratory sample for NTM and were admitted to the Infectious Disease Unit and the Section of Respiratory Medicine...
November 2, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27692463/variability-in-management-of-first-cerebrospinal-fluid-shunt-infection-a-prospective-multi-institutional-observational-cohort-study
#17
Tamara D Simon, Matthew P Kronman, Kathryn B Whitlock, Nancy Gove, Samuel R Browd, Richard Holubkov, John R W Kestle, Abhaya V Kulkarni, Marcie Langley, David D Limbrick, Thomas G Luerssen, Jerry Oakes, Jay Riva-Cambrin, Curtis Rozzelle, Chevis Shannon, Mandeep Tamber, John C Wellons, William E Whitehead, Nicole Mayer-Hamblett
OBJECTIVES: To describe the variation in approaches to surgical and antibiotic treatment for first cerebrospinal fluid (CSF) shunt infection and adherence to Infectious Diseases Society of America (IDSA) guidelines. STUDY DESIGN: We conducted a prospective cohort study of children undergoing treatment for first CSF infection at 7 Hydrocephalus Clinical Research Network hospitals from April 2008 through December 2012. Univariate analyses were performed to describe the study population...
December 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27690120/discrepancy-in-vancomycin-auc-mic-ratio-targeted-attainment-based-upon-the-susceptibility-testing-in-staphylococcus-aureus
#18
Seenae Eum, Robert L Bergsbaken, Craig L Harvey, J Bryan Warren, John C Rotschafer
This study demonstrated a statistically significant difference in vancomycin minimum inhibitory concentration (MIC) for Staphylococcus aureus between a common automated system (Vitek 2) and the E-test method in patients with S. aureus bloodstream infections. At an area under the serum concentration time curve (AUC) threshold of 400 mg∙h/L, we would have reached the current Infectious Diseases Society of America (IDSA)/American Society of Health System Pharmacists (ASHP)/Society of Infectious Diseases Pharmacists (SIDP) guideline suggested AUC/MIC target in almost 100% of patients while using the Vitek 2 MIC data; however, we could only generate 40% target attainment while using E-test MIC data (p < 0...
September 27, 2016: Antibiotics
https://www.readbyqxmd.com/read/27610175/a-prospective-study-to-assess-vancomycin-serum-concentrations-inpediatric-patients-with-current-dosing-guidelines
#19
Peyman Arfa, Abdollah Karimi, Sedigheh Rafiei Tabatabaei, Alireza Fahimzad, Shahnaz Armin, Mohammad Sistanizad
Concerns about increasing bacterial resistance to vancomycin, have caused the adult treatment guidelines to recommend higher trough concentrations based on the type and location of infectious disease. Although these recommendations are not specific to children, the values can be extrapolated. This prospective study was designed to evaluate efficacy of current vancomycin dosing recommendations to achieve therapeutic trough serum concentration in pediatric patients. Laboratory data, vancomycin dosing and subsequent serum concentrations of children in a community teaching pediatrics hospital were collected and analyzed...
2016: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/27587550/the-ers-endorsed-official-ats-cdc-idsa-clinical-practice-guidelines-on-treatment-of-drug-susceptible-tuberculosis
#20
EDITORIAL
Giovanni Sotgiu, Payam Nahid, Robert Loddenkemper, Ibrahim Abubakar, Marc Miravitlles, Giovanni Battista Migliori
No abstract text is available yet for this article.
October 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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