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Partial nephrectomy

Riccardo Bertolo, Juan Garisto, Julien Dagenais, Jose Agudelo, Sherif Armanyous, Michael Lioudis, Jihad Kaouk
OBJECTIVES: To compare functional outcomes of warm ischemia RPN (wRPN) to cold ischemia RPN (cRPN) in "at risk" patients. MATERIALS AND METHODS: Retrospective review of Institutional database queried for all patients who underwent cRPN/wRPN (January 2007 - December 2016). For the study purpose, patients with solitary kidney and/or history of partial nephrectomy and/or multiple tumors and/or preoperative eGFR <60 ml/min were extracted. To reduce inherent biases, groups were matched on key variables related to renal function via a greedy matching algorithm with no replacement...
June 21, 2018: Journal of Endourology
Taiki Kambara, Ryuta Tanimoto, Motoo Araki, Takashi Saika, Hideaki Hashimoto, Tadashi Oeda, Tomoyasu Tsushima, Shunji Hayata, Yasutomo Nasu, Yasuyuki Kobayashi
We retrospectively analyzed the factors related to postoperative cardiovascular (CV) events in patients undergoing partial nephrectomy (PN) or radical nephrectomy (RN) for clinical T1 renal cell carcinoma (RCC). We identified 570 patients who underwent PN or RN for T1 renal cell carcinoma between January 1998 and December 2009 at our institution and related hospitals. We determined the cumulative incidence rate of CV events and overall survival (OS) using Kaplan-Meier survival curves with a log-rank test, and we evaluated the risk for an increase in CV events and OS using Cox proportional hazard regression...
June 2018: Acta Medica Okayama
Ali Abdel Raheem, Tae Young Shin, Ki Don Chang, Glen Denmer R Santok, Mohamed Jayed Alenzi, Young Eun Yoon, Won Sik Ham, Woong Kyu Han, Young Deuk Choi, Koon Ho Rha
OBJECTIVES: To develop a predictive nomogram for chronic kidney disease-free survival probability in the long term after partial nephrectomy. METHODS: A retrospective analysis was carried out of 698 patients with T1 renal tumors undergoing partial nephrectomy at a tertiary academic institution. A multivariable Cox regression analysis was carried out based on parameters proven to have an impact on postoperative renal function. Patients with incomplete data, <12 months follow up and preoperative chronic kidney disease stage III or greater were excluded...
June 19, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
Bruce Gao, Emeka Nzekwu, Anthony Jonathan Cook, Shelley Jane Spaner
BACKGROUND: Nephroblastomatosis is an uncommon pathologic process characterized by the presence of persistent embryonic nephrogenic rests. Progression to Wilms tumour occurs in an estimated 35% of patients. Cure rates are based on histologic findings and disease stage and have improved from 10% in the 1920s to over 90% today. CASE PRESENTATION: We report a case of a 9-month-old female presenting with a 2-month history of abdominal distension. Ultrasonographic and computed tomographic assessments demonstrated features consistent with bilateral, diffuse, hyperplastic perilobar nephroblastomatosis (DHPLNB) for which she underwent chemotherapy...
June 19, 2018: BMC Research Notes
Abimbola Ayangbesan, David M Golombos, Ron Golan, Padraic O'Malley, Patrick Lewicki, Xian Wu, Douglas Scherr
PURPOSE: While surgical approach has recently been associated with positive surgical margin (PSM) following partial nephrectomy (PN) for small (<4 cm) renal masses, its impact on margin status for large (>4 cm) masses is unclear. We sought to evaluate the relationship between margin and surgical approach in patients undergoing PN for large renal masses. MATERIALS AND METHODS: Using the National Cancer Database (NCDB), we identified patients undergoing PN for pathological T1b and T2a renal cell carcinoma (RCC) diagnosed from 2010 to 2013...
June 19, 2018: Journal of Endourology
Carmen M Perrino, Jason A Orien, Jason G Tretter, Weiqiang Zhao, Debra L Zynger
Chromosome 3p deletion is a well-established genetic aberration in clear cell renal cell carcinoma (RCC). We aimed to evaluate the clinical utility of 3p fluorescence in situ hybridization (FISH) on formalin-fixed paraffin-embedded tissue in surgical pathology specimens. 3p:3q <0.8 was established as the cut-off for 3p loss. The 2015 Medicare allowable billing rates were used to estimate the cost. Over 2.5 years (2013 to 2015), 3p FISH was performed on 18 cases per year. Among tested cases, 70% (30/43) were nephrectomies and 30% (14/43) metastases...
June 15, 2018: Applied Immunohistochemistry & Molecular Morphology: AIMM
Vanessa Acosta Ruiz, Sam Ladjevardi, Einar Brekkan, Michael Häggman, Maria Lönnemark, Lisa Wernroth, Anders Magnusson
Background Comparable oncological outcomes have been seen after surgical nephrectomy and thermal ablation of renal tumors recently. However, periprocedural outcome needs to be assessed for aiding treatment decision. Purpose To compare efficacy rates and periprocedural outcome (technical success, session time, hospitalization time, and complications) after renal tumor treatment with laparoscopic partial nephrectomy (LPN) or radiofrequency ablation (RFA). Material and Methods The initial experience with 49 (treated with LPN) and 84 (treated with RFA) consecutive patients for a single renal tumor (diameter ≤ 5 cm, limited to the kidney) during 2007-2014 was evaluated...
January 1, 2018: Acta Radiologica
Juan D Garisto, Riccardo Bertolo, Jihad Kaouk
OBJECTIVES: To describe step-by-step the port placement and the robot docking of the new purpose-built robotic platform for R-LESS. The feasibility of different approaches to the pelvic fossa and the retroperitoneum was reported in cadaver models. METHODS: This was a preclinical study on human cadavers to assess the feasibility of the da Vinci SP1098 surgical system for R-LESS pelvic fossa and retroperitoneal urological surgeries. We used the SP1098 to perform R-LESS prostatectomies and cysto-prostatectomies with transperineal and transvesical approaches, and nephrectomies (radical or partial) with retroperitoneal approach...
June 13, 2018: Urology
Anobel Y Odisho, Ruth Etzioni, John L Gore
BACKGROUND: Safety-net hospitals (SNHs) care for more patients of low socioeconomic status (SES) than non-SNHs and are disproportionately punished under SES-naive Medicare readmission risk-adjustment models. This study was designed to develop a risk-adjustment framework that incorporates SES and to assess the impact on readmission rates. METHODS: California Office of Statewide Health Planning and Development data from 2007 to 2011 were used to identify patients undergoing radical cystectomy (RC) for bladder cancer (n = 3771) or partial nephrectomy (PN; n = 5556) or radical nephrectomy (RN; n = 13,136) for kidney cancer...
June 15, 2018: Cancer
Zheng-Fei Hu, Shi-Dong Lv, Jian-Feng Huang, Lin Zhang, Chan-Tao Huang, Yi-Wen Li, Wen-Hua Huang, Jian-Ping Ye, Qiang Wei
OBJECTIVE: To analyze the advantages of spatial measurement of anatomical parameters in a 3D model in surgical planning for laparoscopic partial nephrectomy (LPN). METHODS: From February, 2016 to October, 2017, 37 patients diagnosed with T1 renal mass underwent LPN based on 3D reconstruction after enhanced CT scanning using the Uromedix-3D system (group A), and another 38 patients received LPN with conventional CT planning (group B). The anatomical parameters were measured in the reconstructed 3D model and the demographic data, surgical outcome and postoperative data were compared between the two groups...
May 20, 2018: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
Sezim Agizamhan, Feng Qu, Ning Liu, Jing Sun, Wei Xu, Lihua Zhang, Hongqian Guo, Weidong Gan
BACKGROUND: The preoperative neutrophil-to-lymphocyte ratio (NLR), C-reactive protein/albumin ratio (CRP/Alb ratio) and platelet-to-lymphocyte ratio (PLR) have been demonstrated to predict the clinical outcome of various human cancer, including renal cell carcinoma(RCC). The aim of our study was to explore the prognostic values of these ratios in patients with Xp11.2 translocation/TFE3 gene fusions renal cell carcinoma (Xp11.2 tRCC). METHODS: A retrospective multicentre study was performed in 82 Xp11...
June 11, 2018: BMC Urology
Angling Yunanto, Irfan Wahyudi, Agus Rizal A H Hamid, Arry Rodjani
No abstract text is available yet for this article.
July 2018: Urology Case Reports
Nina N Harke, Philipp Mandel, Jorn H Witt, Christian Wagner, Andrej Panic, Anselm Boy, Alexander Roosen, Burkhard Ubrig, Andreas Schneller, Frank Schiefelbein, Nina Wagener, Patrick Honeck, Georg Schoen, Boris Hadaschik, Maurice S Michel, Maximilian C Kriegmair
BACKGROUND: To compare the outcomes of robot-assisted (RAPN) and open partial nephrectomy (OPN) for completely endophytic renal tumors. METHODS: Consecutive patients undergoing OPN or RAPN for entirely endophytic tumors in four high-volume centers between 2008 and 2016 were identified. Endophytic masses were identified based on sectional imaging. Patient characteristics and surgical outcome were compared using Mann-Whitney-U-test and chi-squared-tests. Uni- and multivariate analyses were performed to identify predictors of TRIFECTA achievement and excisional volume loss...
June 7, 2018: Journal of Surgical Oncology
Brian M Blair, Erik B Lehman, Syed M Jafri, Matthew G Kaag, Jay D Raman
PURPOSE: The purpose of the study was to evaluate the accuracy of the American College of Surgeons NSQIP Surgical Risk Calculator for predicting risk-adjusted 30-day outcomes for patients undergoing partial nephrectomy (PN) for renal cell carcinoma (RCC). METHODS: A single institution, multi-surgeon, prospectively maintained database was queried for patients undergoing PN for RCC from 1998 to 2015. 21 preoperative factors were analyzed for each patient with predicted risk for 30-day complications, mortality, and length of stay (LOS) calculated...
June 4, 2018: International Urology and Nephrology
Shinji Kishi, Hiroyuki Monma, Hiroshige Hori, Shoichi Kinugasa, Masayo Fujimoto, Takeshi Nakamura
BACKGROUND Giant cell tumor of soft tissue (GCT-ST) is a rare disease generally generated from superficial tissue. We report an extremely rare case of giant cell tumor of soft tissue arising from retroperitoneal tissue. CASE REPORT A 78-year-old man visited our medical center with the chief complaint of fatigue and weight loss for 1 month. He had a hard and immobilized mass without pain in the left upper quadrant. Contrast-enhanced CT showed a huge tumor (22×20×16 cm) in the retroperitoneal space, and it invaded into the stomach, colon, pancreas, spleen, and left kidney...
June 5, 2018: American Journal of Case Reports
William Keith Ballentine, Fernandino Vilson, Raymond B Dyer, Majid Mirzazadeh
BACKGROUND: Xanthogranulomatous pyelonephritis (XGP) is an uncommon infectious disease of the kidney known to mimic other renal maladies. A rare presentation of this uncommon disease is spontaneous renal hemorrhage (SRH). CASE PRESENTATION: We report a case of XGP in a 58 year old woman who presented with abdominal pain, hematuria, and radiating left flank pain. CT scan was felt to be consistent with perirenal hemorrhage abutting a fat-containing renal mass. The patient was eventually taken to surgery for left partial nephrectomy...
June 5, 2018: BMC Urology
Jonathan Gapp, Muhammad Fazeel Anwar, Jai Parekh, Timothy Griffin
A 61-year-old male was admitted from the outpatient setting for treatment of severe hyperglycemia. Five months earlier, his hemoglobin A1c had been 5 mmol/mol. At presentation, hemoglobin A1c was 11.3 mmol/mol and he required insulin therapy at discharge. Later magnetic resonance imaging (MRI) identified bilateral renal masses, previously seen on ultrasound during workup for chronic kidney disease, as being suspicious for renal cell carcinoma (RCC). He underwent partial nephrectomy and cryoablation with pathology showing papillary type RCC...
May 2018: Intractable & Rare Diseases Research
Robert S Figenshau
No abstract text is available yet for this article.
May 31, 2018: Journal of Endourology
Charbel Chalouhy, Jessica Moore Ruck, Tian Cheng Zhou, Abhishek Srivastava, Aryeh Keehn, Kara L Watts, Pedro Maria, Reza Ghavamian
BACKGROUND: Minimal literature informs the use of robotic partial nephrectomy (RPN) in patients with chronic kidney disease (CKD). Therefore, we evaluated the renal functional outcomes in CKD patients undergoing RPN. METHODS: We reviewed a prospective database of patients undergoing RPN 2010-2015 and identified 182 patients who had preoperative and postoperative nuclear renal scintigraphy (at 2 and 12 months postop). Pre-operative and 12-month post-operative eGFR (mL/min/1...
May 31, 2018: Journal of Endourology
N H Azawi, S A Tolouee, M Madsen, K D Berg, C Dahl, M Fode
PURPOSE: The purpose of the study was to evaluate the diagnostic accuracy of core biopsy in small renal masses ≤ 4 cm in response to the rising prevalence of renal masses. METHODS: Data from 129 consecutive patients who underwent biopsies of solid renal masses of ≤ 4 cm were prospectively collected between September 2014 and January 2017. In cases with inconclusive biopsies, a repeat biopsy was recommended. Histology from surgical specimens was used as gold standard to evaluate the accuracy of renal biopsies...
May 30, 2018: International Urology and Nephrology
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