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Partial nephrectomy

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https://www.readbyqxmd.com/read/29051004/assessing-time-of-full-renal-recovery-following-minimally-invasive-partial-nephrectomy
#1
Mark T Dawidek, Ernest Chan, Shawna L Boyle, Alp Sener, Patrick P Luke
OBJECTIVE: To assess renal function in the operated kidney at different time points post partial nephrectomy (PN) and establish the time in which optimal recovery occurs. Recovery of renal function post-PN has received significant attention. However, the optimal time to determine full recovery has not been clearly established. METHODS: Renal function following minimally invasive (laparoscopic and robotic) PNs performed between 2002 and 2015 was reviewed. Patients included in this study had renal function assessed pre-operatively as well as 3 days, 6-12 weeks, and 1 year post-PN, using a combination of estimated glomerular filtration rate (eGFR) from serum creatinine and relative renal uptake (RRU) from Tc99m-MAG3 renal scintigraphy...
October 16, 2017: Urology
https://www.readbyqxmd.com/read/29048977/off-clamp-robot-assisted-partial-nephrectomy-how-far-shall-we-proceed
#2
Ali Abdel Raheem, Glen Denmer Santok, Lawrence H C Kim, Ki Don Chang, Trenton G H Lum, Young Eun Yoon, Woong Kyu Han, Young Deuk Choi, Koon Ho Rha
BACKGROUND: Off-clamp robot-assisted partial nephrectomy (RAPN) is associated with increased intraoperative blood loss compared with on-clamp technique. Our aim was to demonstrate our surgical technique and to determine which tumors are ideally suited for this technique. METHODS: Sixty-two patients who underwent off-clamp RAPN for renal tumor between 2006 and 2016 were retrospectively analyzed. Increased estimated blood loss (EBL) volume was defined as more than 75 percentile...
October 19, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29048228/predictive-factors-for-achieving-superior-pentafecta-outcomes-following-robot-assisted-partial-nephrectomy-in-patients-with-localized-renal-cell-carcinoma
#3
Minyong Kang, In-Hyuck Gong, Hwi Jun Park, Hyun Hwan Sung, Hwang Gyun Jeon, Byong Chang Jeong, Seong Soo Jeon, Hyun Moo Lee, Han Yong Choi, Seong Il Seo
PURPOSE: To examine the perioperative outcomes following robot-assisted partial nephrectomy (RAPN) in patients with localized renal cell carcinoma (RCC) and to identify the predictors of Pentafecta achievement following RAPN. MATERIALS AND METHODS: We retrospectively analyzed the data from 362 patients with RCC who underwent RAPN from 2008 to 2016. The criteria for Pentafecta achievement was defined as the Trifecta [warm ischemia time (WIT) ≤ 25 minutes, negative surgical margin, and no significant perioperative complications]; with the addition of renal function preservation, including over 90% preservation of the estimated-glomerular filtration rate (e-GFR); and no stage upgrade of chronic kidney disease at 1 year after surgery...
October 19, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29044535/incidence-and-histologic-features-of-mixed-renal-tumors
#4
Neil J Kocher, Chris Rjepaj, Erik Lehman, Jay D Raman
BACKGROUND AND OBJECTIVES: Guidelines for management of renal cell carcinoma (RCC) incompletely address the implications of mixed renal tumor histology. We investigate the incidence of mixed renal tumors identified at renal surgery and determine the association with pathologic features. METHODS: Institutional kidney tumor database was reviewed to identify 536 patients who underwent partial or radical nephrectomy. Clinical, demographic, and pathologic data were collected...
October 16, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29042169/percutaneous-cryoablation-of-renal-cell-carcinoma-with-sinus-vein-involvement-based-on-preprocedural-imaging
#5
Thomas D Atwell, A Nicholas Kurup, Stephen A Boorjian, John J Schmitz, R Houston Thompson, Bradley C Leibovich, Grant D Schmit
PURPOSE: To assess feasibility, safety, and oncologic outcomes of cryoablation in treatment of renal cell carcinoma (RCC) with extension into adjacent renal sinus vein. MATERIALS AND METHODS: Review of an internally maintained renal ablation registry identified 7 patients (4 men and 3 women; median age 62 y; age range, 45-91 y) who underwent percutaneous cryoablation of RCC with imaging consistent with extension of tumor into an immediately adjacent renal sinus vein...
October 14, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29034658/guidelines-of-the-italian-society-of-videosurgery-in-infancy-for-the-minimally-invasive-treatment-of-pediatric-nephrectomy-and-partial-nephrectomy
#6
Salvatore Fabio Chiarenza, Cosimo Bleve, Ciro Esposito, Maria Escolino, Fabio Beretta, Maurizio Cheli, Vincenzo Di Benedetto, Maria Grazia Scuderi, Giovanni Casadio, Maurizio Marzaro, Leon Francesco Fascetti, Pietro Bagolan, Claudio Vella, Maria Luisa Conighi, Daniela Codric, Simona Nappo, Paolo Caione
Not available.
October 4, 2017: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
https://www.readbyqxmd.com/read/29032581/utilization-and-quality-outcomes-of-ct1a-ct1b-and-ct2a-partial-nephrectomy-analysis-of-the-national-cancer-database
#7
Katherine Fero, Zachary A Hamilton, Ahmet Bindayi, James D Murphy, Ithaar H Derweesh
OBJECTIVE: To describe utilization and compare quality outcomes of partial nephrectomy (PN) for cT1a, cT1b and cT2a renal mass using a large national database. METHODS: Retrospective analysis of patients from the US National Cancer Database who underwent PN for cT1a/cT1b/T2a renal cell carcinoma between 2004-2013. We examined utilization of PN over time and quality indicators [positive surgical margin (PSM) and 30-day postoperative readmission rates (30Day-Readmit)]...
October 15, 2017: BJU International
https://www.readbyqxmd.com/read/29027269/partial-nephrectomy-for-small-children-robot-assisted-versus-open-surgery
#8
Quentin Ballouhey, Aurélien Binet, Pauline Clermidi, Karim Braik, Thierry Villemagne, Jérôme Cros, Hubert Lardy, Laurent Fourcade
OBJECTIVES: To compare the outcomes of robot-assisted heminephrectomy for duplex kidney in children with those of open heminephrectomy. METHODS: The present retrospective multicentric analysis reviewed the records of robot-assisted versus open heminephrectomy carried out for duplex kidney in children from 2007 to 2014. Demographic data, weight, surgical time, hospital stay, complications and outcome were recorded. Follow up was based on a clinical review, renal sonography and dimercaptosuccinic acid renal scintigraphy...
October 13, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29024738/new-hybrid-mini-laparoendoscopic-single-site-mi-less-partial-nephrectomy-with-early-unclamped-technique-for-renal-tumors-with-intermediate-padua-score-ideal-phase-2a
#9
Christopher Springer, Felix Kawan, Roberto La Rocca, Nasreldin Mohammed, Paolo Fornara, Vincenzo Mirone, Francesco Greco
OBJECTIVE: To evaluate a new hybrid technique which we defined mini-laparoendoscopic single-site partial nephrectomy (MILESS-PN) for renal masses presenting an intermediate PADUA score. MATERIAL AND METHODS: Forty consecutive cases of MILESS-PN performed between April 2013 and November 2015 were included in this study. MILESS consisted in the simultaneous use of two 3 mm pararectal trocars and an umbilical SILS trocar; the sequence of steps of MILESS-PN was comparable to standard laparoscopic partial nephrectomy...
October 9, 2017: Urology
https://www.readbyqxmd.com/read/29022072/effect-of-pathological-high-risk-features-on-cancer-specific-mortality-in-non-metastatic-clear-cell-renal-cell-carcinoma-a-tool-for-optimizing-patient-selection-for-adjuvant-therapy
#10
Marco Bandini, Ariane Smith, Emanuele Zaffuto, Raisa S Pompe, Michele Marchioni, Umberto Capitanio, Felix K Chun, Anil B Kapoor, Shahrokh F Shariat, Francesco Montorsi, Alberto Briganti, Pierre I Karakiewicz
PURPOSE: Adjuvant therapies for non-metastatic renal cell carcinoma (nmRCC) are being tested to improve outcomes in patients with high-risk (hR) nmRCC. The objective of the current study is to test the ability of three hR features to identify patients who are at the highest risk of cancer-specific mortality (CSM) after partial or radical nephrectomy. METHODS: Within the Surveillance Epidemiology and End Results (SEER) database (1988-2013), we identified 23,632 nm "clear cell" RCC partial or radical nephrectomy patients with hR features: Fuhrman grade (FG) 3 or 4 or pathological classifications T3a or T3b or lymph node invasion (LNI), or combination of these...
October 11, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29018140/incident-ckd-after-radical-or-partial-nephrectomy
#11
John T Leppert, Remy W Lamberts, I-Chun Thomas, Benjamin I Chung, Geoffrey A Sonn, Eila C Skinner, Todd H Wagner, Glenn M Chertow, James D Brooks
The comparative effectiveness of partial nephrectomy versus radical nephrectomy to preserve kidney function has not been well established. We determined the risk of clinically significant (stage 4 and higher) CKD after radical or partial nephrectomy among veterans treated for kidney cancer in the Veterans Health Administration (2001-2013). Among patients with preoperative eGFR≥30 ml/min per 1.73 m(2), the incidence of CKD stage 4 or higher after radical (n=9759) or partial nephrectomy (n=4370) was 7.9% overall...
October 10, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29017411/occult-langerhans-cell-histiocytosis-in-clear-cell-renal-cell-carcinoma
#12
Hee Jung Kwon, Phil Hyun Song, Mi Jin Gu
Langerhans cell histiocytosis is a rare disease that is characterized by a localized or systemic proliferation of Langerhans dendritic cells and a wide spectrum of clinical presentations. We experienced an unusual case of occult Langerhans cell histiocytosis associated with clear cell renal cell carcinoma. A 62-year-old man underwent a partial nephrectomy for left renal mass. Histologic examination showed nests of clear cells with surrounding thin-walled vessel that were suggestive of clear cell renal cell carcinoma...
October 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28993059/perioperative-blood-transfusion-adversely-affects-prognosis-after-nephrectomy-for-renal-cell-carcinoma
#13
Yasmin Abu-Ghanem, Dorit E Zilberman, Zohar Dotan, Issac Kaver, Jacob Ramon
BACKGROUND: It has been previously suggested that perioperative blood transfusion (PBT) may induce adverse oncological outcomes following cancer surgery. The aim of the current study is to evaluate the effect of PBT on the prognosis of patients who underwent nephrectomy due to renal cell carcinoma (RCC). METHODS: Study included 1,159 patients who underwent radical nephrectomy or partial nephrectomy (PN) between the years 1987 and 2013. Univariate and multivariate models were used to evaluate the association of PBT with cancer-specific survival (CSS), disease-free survival, and overall survival (OS)...
October 6, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28985968/should-urologists-abandon-the-use-of-mannitol-during-partial-nephrectomy
#14
EDITORIAL
Paras H Shah, Bradley C Leibovich, Timothy D Lyon
No abstract text is available yet for this article.
October 3, 2017: European Urology
https://www.readbyqxmd.com/read/28984770/management-of-iatrogenic-renal-arteriovenous-fistula-and-renal-arterial-pseudoaneurysm-by-transarterial-embolization-a-single-center-analysis-and-outcomes
#15
Hongjie Guo, Chengen Wang, Min Yang, Xiaoqiang Tong, Jian Wang, Haitao Guan, Li Song, Yinghua Zou
The purpose of this study was to evaluate the efficacy and safety of transarterial embolization (TAE) for iatrogenic renal arterial pseudoaneurysm and arteriovenous fistula at our center.Our retrospective analysis included 27 patients who received TAE for iatrogenic renal arterial pseudoaneurysm and arteriovenous fistula between January 2006 and January 2016. Data on demographics, type of minimally invasive renal procedures, clinical manifestation, imaging features, embolization procedure, and perioperative details were collected...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28977844/high-expression-of-fut3-is-linked-to-poor-prognosis-in-clear-cell-renal-cell-carcinoma
#16
Li Meng, Le Xu, Yuanfeng Yang, Lin Zhou, Yuan Chang, Tianming Shi, Cheng Tan, Huimin An, Yu Zhu, Jiejie Xu
BACKGROUND AND PURPOSE: Some of the fucosylation catalyzed by fucosyltransferase-III mediates the epithelial-mesenchymal transition and enhances tumor cell-macrophage signaling, which promotes malignant transforming and immune evasion. The aim of the study was to investigate the association between the expression of fucosyltransferase-III and clinical outcomes of patients with clear-cell renal cell carcinoma after surgery. RESULTS: High fucosyltransferase-III expression was associated with a greater risk of recurrence (p = 0...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28970053/incidence-of-t3a-up-staging-and-survival-after-partial-nephrectomy-size-stratified-rates-and-implications-for-prognosis
#17
Arnav Srivastava, Hiten D Patel, Gregory A Joice, Alice Semerjian, Michael A Gorin, Michael H Johnson, Mohamad E Allaf, Phillip M Pierorazio
BACKGROUND: The use of partial nephrectomy (PN) to treat renal cell carcinoma has grown to include larger, more complex tumors. Such tumors are more likely to be up-staged to pT3a and generate controversy regarding the oncologic safety of PN. We aimed to estimate the proportion of patients up-staged to T3a disease after PN, stratified by clinical stage, and characterize their survival. METHODS: From 1998 to 2013, pT1-pT3aN0M0 kidney cancer patients undergoing PN or radical nephrectomy (RN) were identified from the Surveillance Epidemiology and End Results registries...
September 29, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28967553/outcomes-after-cryoablation-versus-partial-nephrectomy-for-sporadic-renal-tumors-in-a-solitary-kidney-a-propensity-score-analysis
#18
Bimal Bhindi, Ross J Mason, Mustafa M Haddad, Stephen A Boorjian, Bradley C Leibovich, Thomas D Atwell, Adam J Weisbrod, Grant D Schmit, R Houston Thompson
BACKGROUND: While partial nephrectomy (PN) is considered the standard approach for a tumor in a solitary kidney, percutaneous cryoablation (PCA) is emerging as an alternative nephron-sparing option. OBJECTIVE: To compare outcomes between PCA and PN for tumors in a solitary kidney. DESIGN, SETTING, AND PARTICIPANTS: Patients who underwent PCA or PN between 2005 and 2015 for a single primary renal tumor in a solitary kidney were identified using Mayo Clinic Registries...
September 26, 2017: European Urology
https://www.readbyqxmd.com/read/28967280/comprehensive-approach-to-port-placement-templates-for-robotic-assisted-laparoscopic-urologic-surgeries
#19
Ram A Pathak, Manish Patel, Ashok Hemal
Port placement for robotic-assisted laparoscopic urologic surgery can be critical to successful completion of the minimally invasive procedure. An ideal port template would allow unhampered access to all critical structures during surgery, easy access for the bedside assistant, and minimization of arm collision with the fewest ports necessary to minimize cosmetic impact. We present a comprehensive plan for the placement of ports across different procedures for a variety of upper tract (radical/partial nephrectomy, retroperitoneal radical/partial nephrectomy, and pyeloplasty), lower tract (prostatectomy, and cystectomy), combined upper/lower tract (nephroureterectomy, retroperitoneal lymph node dissection), and female pelvic surgeries...
October 1, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28962877/is-cryotherapy-a-genuine-rival-to-robotic-assisted-partial-nephrectomy-in-the-management-of-suspected-renal-malignancy-a-systematic-review-and-meta-analysis
#20
REVIEW
Bhavan Prasad Rai, Patrick Jones, Campbell Tait, Ramachandran Amitharaj, Raj Gowda, Aftab Bhatti, Jim Adshead, Bhaskar Somani
We systematically reviewed world literature and compare oncological outcomes, morbidity, renal function and peri-operative outcome between cryotherapy (CA) and robotic assisted partial nephrectomy (RAPN) for suspected renal malignancy. There was a statistically significant difference for "recurrence rates" between the 2 techniques, favouring the RAPN cohort. There was no statistically significant difference in overall and ≥Clavien 3a complication rates between the 2 techniques. The quality of evidence for recurrence rates, overall complication and ≥Clavien 3a were 'moderate', 'low' and 'very low' respectively on GRADE approach...
September 26, 2017: Urology
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