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Partial nephrectomy

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https://www.readbyqxmd.com/read/28440053/who-is-at-risk-of-death-from-nephrectomy-an-analysis-of-thirty-day-mortality-after-21-380-nephrectomies-in-3-years-of-the-british-association-of-urological-surgeons-baus-national-nephrectomy-audit
#1
Archie Fernando, Sarah Fowler, Mieke Van Hemelrijck, Tim O'Brien
OBJECTIVE: To ascertain contemporary overall and differential thirty-day mortality (TDM) rates after all types of nephrectomy in the UK, and to identify potential new risk factors for death. PATIENTS AND METHODS: We conducted a retrospective analysis of the 110 deaths that occurred within 30 days of surgery out of the total of 21 380 nephrectomies performed, and calculated the odds ratio (OR) and 95% confidence interval (CI) for TDM based on peri-operative characteristics...
April 24, 2017: BJU International
https://www.readbyqxmd.com/read/28438756/migration-of-clips-to-the-colon-after-laparoscopic-partial-nephrectomy
#2
Peter Fisker Vedel, Hans-Erik Wittendorf, Thomas Peter Norus
A 78-year-old man was treated with laparoscopic partial nephrectomy for a 4 cm tumour in the lower pole of the left kidney. The patient was discharged 2 days postoperatively. Preoperatively there was no sign of metastasis; the pathology indicated complete removal of the tumour, a renal cell carcinoma. 53 days postoperatively the patient had acute onset of rectal bleeding. A colonoscopy revealed necrosis and three clips on the wall of the colon corresponding to where the descending colon passes over the left kidney...
April 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28437169/re-maurice-et-al-multiple-tumor-excisions-in-ipsilateral-kidney-increase-complications-after-partial-nephrectomy
#3
Adam R Metwalli
The presence of multiple tumors in an ipsilateral kidney leads to different peri-operative outcomes and increased complications. This is particularly important now that compensation is being linked to surgical outcomes. Thus it is important for urologic surgeons to clearly define what complication rates are for each type of case and clearly define how these cases differ from standard partial nephrectomies.
February 10, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28437021/optimal-outcome-achievement-in-partial-nephrectomy-for-t1-renal-masses-a-contemporary-analysis-of-open-and-robotic-cases
#4
Matthew J Maurice, Daniel Ramirez, Önder Kara, Ercan Malkoç, Ryan J Nelson, Khaled Fareed, Robert J Stein, Amr F Fergany, Jihad H Kaouk
OBJECTIVES: To compare optimal outcome achievement between open and robotic partial nephrectomy. PATIENTS AND METHODS: Using our institutional partial nephrectomy database, we reviewed 605 cases performed for unifocal clinical T1 renal masses in non-solitary kidneys from 2011-2015. Tetrafecta, which was defined as negative surgical margins, freedom from perioperative complications, ≥80% renal functional preservation, and no chronic kidney disease upstaging, was chosen as the composite optimal outcome...
April 24, 2017: BJU International
https://www.readbyqxmd.com/read/28436368/-pseudo-pseudoaneurysm-following-robotic-assisted-partial-nephrectomy
#5
Eric Schommer, Julio Gundian, David D Thiel
A 65-year-old female presented to clinic requesting follow up for a history of right robotic partial nephrectomy done at an outside institution 2 years prior. Initial pathology demonstrated a grade 2/4 3.4 cm clear cell renal cell carcinoma with negative margins. There was no tumor necrosis, sarcomatoid differentiation, or lymphovascular invasion. High quality follow up imaging initially revealed a pseudoaneurysm in the central portion of the right kidney. The patient was sent to interventional radiology for angioembolization...
April 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28436354/what-is-the-current-role-of-partial-nephrectomy-for-t2-tumors
#6
Bruno Nahar, Mark L Gonzalgo
INTRODUCTION: To review oncological and functional outcomes for partial nephrectomy in the setting of T2 tumors. MATERIALS AND METHODS: We performed a comprehensive literature review on partial nephrectomy for T2 tumors, focusing on major primary series reporting oncological and functional outcomes, as well as complication rates in the last 10 years. RESULTS: Recent series have reported comparable oncological outcomes between partial nephrectomy and radical nephrectomy for ≥ T2 tumors...
April 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28435792/retroperitoneoscopic-partial-nephrectomy-for-a-horseshoe-kidney-tumor
#7
David Nikoleishvili, Givi Koberidze
Horseshoe kidney is the most common renal fusion anomaly found in about 0.15% to 0.25% of the population. Renal cell carcinoma associated with a horseshoe kidney has been described in fewer than 200 cases. Its incidence and prognosis seems to be not different from those of the general population, but surgical management may be challenging due to unique anatomic features of horseshoe kidneys, such as highly variable vasculature. We report a case of a 69-year-old male with an incidental 48-mm solid mass in the left moiety of a horseshoe kidney, successfully treated by retroperitoneoscopic partial nephrectomy...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28427128/-the-application-value-of-contrast-enhanced-ultrasound-in-the-surgery-of-renal-masses
#8
M H Liu, J H Shi, Q M H Wangqi, Y Q Lin, Z X Sun
Objective: To investigate the clinical value of contrast-enhanced ultrasound in the diagnosis of renal masses. Methods: A total of 50 patients with renal masses who underwent partial nephrectomy were analyzed from January 2014 to October 2016 in the Department of Urology of China-Japan Union Hospital of Jilin University.In the intraoperative contrast-enhanced ultrasound, the characteristics of ultrasound imaging were recorded including location, size, boundary, echo, real-time internal and peripheral blood and renal pelvis distance, artery, guidance on the selection of surgical methods, intraoperative real-time estimation of the extent of tumor resection...
April 18, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28421626/editorial-comment-from-dr-teishima-and-dr-matsubara-to-clinical-application-of-calculated-split-renal-volume-using-computed-tomography-based-renal-volumetry-after-partial-nephrectomy-correlation-with-technetium-99m-dimercaptosuccinic-acid-renal-scan-data
#9
Jun Teishima, Akio Matsubara
No abstract text is available yet for this article.
April 18, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28420902/a-combination-therapy-of-partial-nephrectomy-and-cryoablation-achieved-good-cancer-control-and-renal-function-in-bilateral-synchronous-renal-cell-carcinoma
#10
Atsushi Takamoto, Motoo Araki, Koichiro Wada, Morito Sugimoto, Yasuyuki Kobayashi, Katsumi Sasaki, Toyohiko Watanabe, Yasutomo Nasu
We report the case of a 58-year-old Japanese man with bilateral synchronous renal cell carcinoma (RCC). The diameters of the right and left tumors were 56 and 69 mm, respectively. Both tumors were endophytic. Cryoablation with prophylactic embolization was performed for the left tumor, and 1 month later, a right open partial nephrectomy was performed. No recurrence was observed during a 16-month follow-up, and the serum creatinine level has been stable. The prognosis of bilateral synchronous RCC is better than that of dialysis patients...
April 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/28417354/perioperative-epidural-analgesia-is-not-associated-with-increased-survival-from-renal-cell-cancer-but-overall-survival-may-be-improved-a-retrospective-chart-review
#11
Evan Kovac, Farhad Firoozbakhsh, Homayoun Zargar, Amr Fergany, Hesham Elsharkawy
PURPOSE: We investigated the possible association between perioperative epidural and both cancer-specific survival (CSS) and overall survival (OS) in patients undergoing partial or radical nephrectomy for localized renal cell carcinoma (RCC). METHODS: A retrospective chart review was performed on patients who underwent complete surgical resection of localized RCC from 1994-2008 at our institution. Baseline demographics and pathological and survival data were collected...
April 17, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28417341/external-validation-of-a-nomogram-including-the-computed-tomography-imaging-score-to-predict-indolent-renal-masses
#12
X Chen, B Wan, D Yang, H Zhao, W Tan
PURPOSE: To assess a nomogram including the computed tomography (CT) score and body mass index (BMI) that was constructed to predict indolent diseases in a cohort of patients with renal masses. MATERIALS AND METHODS: The data collected from patients undergoing partial nephrectomy (PN) or radical nephrectomy (RN) between January 2012 and September 2016 were analyzed. Two urologic surgeons and a radiologist reviewed the images to determine the CT score. Postoperative pathological assessment was performed to categorize renal masses as either indolent or aggressive...
April 17, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28416109/positive-surgical-margins-increase-risk-of-recurrence-after-partial-nephrectomy-for-high-risk-renal-tumors-shah-ph-moreira-dm-okhunov-z-patel-vr-chopra-s-razmaria-aa-alom-m-george-ak-yaskiv-o-schwartz-mj-desai-m-vira-ma-richstone-l-landman-j-shalhav-al-gill
#13
Oleksandr N Kryvenko
PURPOSE: The clinical significance of a positive surgical margin after partial nephrectomy remains controversial. The association between positive margin and risk of disease recurrence in patients with clinically localized renal neoplasms undergoing partial nephrectomy was evaluated. MATERIALS AND METHODS: A retrospective multi-institutional review of 1,240 patients undergoing partial nephrectomy for clinically localized renal cell carcinoma between 2006 and 2013 was performed...
April 13, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28416105/do-clear-cell-papillary-renal-cell-carcinomas-have-malignant-potential-diolombi-ml-cheng-l-argani-p-epstein-ji-am-j-surg-pathol-december-2015-39-12-1621-1634
#14
Oleksandr N Kryvenko
There have been no recurrences or metastases of clear cell papillary renal cell carcinoma (CCPRCC) in 268 reported cases with follow-up in the English-language literature. We identified all our cases of CCPRCC (1990-2013), reviewing all cases that preceded the formal designation of the entity. Immunohistochemical stains were performed on 32 cases during their initial workup. In addition, stains for carbonic anhydrase IX and cytokeratin 7 were performed on 2 cases, one with atypical follow-up and the other with a more compact morphology, although not performed initially...
April 13, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28415596/renal-mass-biopsy-using-raman-spectroscopy-identifies-malignant-and-benign-renal-tumors-potential-for-pre-operative-diagnosis
#15
Yufei Liu, Zhebin Du, Jin Zhang, Haowen Jiang
The accuracy of renal mass biopsy to diagnose malignancy can be affected by multiple factors. Here, we investigated the feasibility of Raman spectroscopy to distinguish malignant and benign renal tumors using biopsy specimens. Samples were collected from 63 patients who received radical or partial nephrectomy, mass suspicious of cancer and distal parenchyma were obtained from resected kidney using an 18-gauge biopsy needle. Four Raman spectra were obtained for each sample, and Discriminant Analysis was applied for data analysis...
March 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/28412331/are-we-using-the-best-tumor-size-cut-points-for-renal-cell-carcinoma-staging
#16
Bimal Bhindi, Christine M Lohse, Ross J Mason, Mary E Westerman, John C Cheville, Matthew K Tollefson, Stephen A Boorjian, R Houston Thompson, Bradley C Leibovich
OBJECTIVE: To compare the predictive ability for oncologic outcomes among current tumor size cut-points and clinically relevant alternatives in order to determine which are optimal. METHODS: Patients who underwent radical or partial nephrectomy between 1970-2010 for T1-2Nx/N0M0 renal cell carcinoma (RCC) were identified. Associations between tumor size and progression-free survival (PFS) and cancer-specific survival (CSS) were evaluated using Kaplan-Meier analyses and Cox models...
April 12, 2017: Urology
https://www.readbyqxmd.com/read/28411920/neoadjuvant-targeted-molecular-therapy-before-renal-surgery
#17
REVIEW
Sumi Dey, Henry N Peabody, Sabrina L Noyes, Brian R Lane
Neoadjuvant targeted molecular therapy may benefit select patients with metastatic renal cell carcinoma. The primary use of this therapy in patients with metastatic disease is to reduce tumor burden, prevent distant metastasis, and increase overall survival. Neoadjuvant therapy may reduce tumor size and tumor complexity, facilitate partial nephrectomy rather than radical nephrectomy, downstage tumor thrombus facilitating thrombectomy, and make unresectable tumors resectable when applied to selected patients...
May 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/28411918/lymph-node-dissection-for-small-renal-masses
#18
REVIEW
Michael L Blute, Mohit Gupta, Paul L Crispen
Because the majority of small renal masses (SRMs; <4 cm) demonstrate low metastatic potential and can be effectively treated with radical or partial nephrectomy, the role of lymph node dissection (LND) at the time of surgery is unclear. A randomized trial demonstrated no survival benefit of LND in clinically localized renal cell carcinoma. Thus, LND is not recommended routinely for SRMs. For patients with high-risk features or radiographic evidence of lymphadenopathy, however, LND may improve local staging and potentially provide a survival benefit...
May 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/28411917/comparative-effectiveness-of-surgical-treatments-for-small-renal-masses
#19
REVIEW
Shree Agrawal, Hillary Sedlacek, Simon P Kim
In the management of small renal masses (SRMs), treatment options include partial nephrectomy (PN), radical nephrectomy (RN), ablation, renal biopsy, and active surveillance. Large series retrospective and meta-analyses demonstrate PN may confer greater preservation of renal function, overall survival, and equivalent cancer control when compared with RN. As newer therapies emerge, we should critically evaluate the risks and benefits associated with the surgical management of SRMs among patients with competing comorbidities, complex tumors, and high-risk disease...
May 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/28411916/renal-ischemia-and-functional-outcomes-following-partial-nephrectomy
#20
REVIEW
Joseph R Zabell, Jitao Wu, Chalairat Suk-Ouichai, Steven C Campbell
Renal function after renal cancer surgery is a critical component of survivorship. Quantity and quality of preserved parenchyma are the most important determinants of functional recovery; type and duration of ischemia play secondary roles. Several studies evaluated surgical techniques to minimize ischemia; however, long-term outcomes and potential benefits over clamped partial nephrectomy (PN) have not been consistently demonstrated. Analysis of acute kidney injury (AKI) after PN suggest that most kidneys recover strongly even if AKI is experienced after surgery...
May 2017: Urologic Clinics of North America
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