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https://www.readbyqxmd.com/read/29673115/the-nuclear-retinoid-related-orphan-receptor-ror%C3%AE-controls-circadian-thermogenic-programming-in-white-fat-depots
#1
Chloé Monnier, Martine Auclair, Gala Le Cam, Marie-Pauline Garcia, Bénédicte Antoine
The RORα-deficient staggerer (sg/sg) mouse is lean and resistant to diet-induced obesity. Its thermogenic activity was shown to be increased not only in brown adipose tissue (BAT), but also in subcutaneous white adipose tissue (WAT) where UCP1 content was enhanced, however, without Prdm16 coexpression. Our observation of partial multilocular lipid morphology of WAT in sg/sg mice both in the inguinal and perigonadal sites led us to focus on the phenotype of both fat depots. Because RORα is a nuclear factor acting in the clock machinery, we looked at the circadian expression profile of genes involved in thermogenesis and browning in WAT and BAT depots of sg/sg and WT mice, through real-time quantitative PCR and western blotting...
April 2018: Physiological Reports
https://www.readbyqxmd.com/read/29650459/examining-the-feasibility-of-healthy-minimum-stocking-standards-for-small-food-stores
#2
Allison Karpyn, Robin S DeWeese, Jennifer E Pelletier, Melissa N Laska, Punam Ohri-Vachaspati, Amy Deahl-Greenlaw, Ogheneruona Ughwanogho, Stephanie Bell Jilcott Pitts
OBJECTIVE: In response to recent national efforts to increase the availability of healthy food in small stores, we sought to understand the extent to which small food stores could implement the newly published Healthy Small Store Minimum Stocking Recommendations and reflect on the new US Department of Agriculture Food and Nutrition Service's final rule for stocking of staple foods for Supplemental Nutrition Assistance Program-approved retailers. DESIGN: We collected qualitative and quantitative data from 57 small stores in four states (Arizona, Delaware, Minnesota, and North Carolina) that accepted Supplemental Nutrition Assistance Program but not Special Supplemental Nutrition Assistance Program for Women, Infants, and Children benefits...
April 9, 2018: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29644889/comparing-exercise-responses-to-aerobic-plus-resistance-training-between-postmenopausal-breast-cancer-survivors-undergoing-aromatase-inhibitor-therapy-and-healthy-women
#3
Thais R S de Paulo, Kerri M Winters-Stone, Juliana Viezel, Fabricio E Rossi, Bruna L Aro, Ana Carolina A C Trindade, Jamile S Codogno, Ismael F Freitas Junior
BACKGROUND: The aim of this study was to explore whether postmenopausal breast cancer survivors undergoing aromatase inhibitor therapy differ from healthy postmenopausal women in their response to the same aerobic + resistance training. METHODS: The participants were separated into two groups: postmenopausal breast cancer survivors undergoing aromatase inhibitor therapy for an average of 20 months (18 women) and healthy postmenopausal women (24 women). We assessed aerobic capacity (predicted maximum oxygen uptake (VO2 max) and maximum running velocity test (Vmax)) through a walking test, upper and lower body muscle strength using an estimated one-repetition maximum test, and body composition by dual-energy X-ray absorptiometry at baseline and at three, six, and nine months, respectively...
April 12, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29642931/bariatric-surgery-improves-knee-function-and-not-knee-pain-in-the-early-postoperative-period
#4
Amre Hamdi, Alia T Albaghdadi, Bayan Ghalimah, Abdullah Alnowiser, Anas Ahmad, Abdulmalik Altaf
BACKGROUND: Obesity remains the strongest predictor of knee osteoarthritis (OA). Studies have reported improvement in knee pain and function post-bariatric surgery secondary to weight loss and reduced mechanical loading, yet others found increased rates of total knee arthroplasty (TKA) in that patient population. To address this controversy, our study aimed to further assess the effect of surgically induced, "rapid" weight loss on knee pain and function. METHODS: Obese patients with chronic knee pain, who were undergoing bariatric surgery, were enrolled and surveyed preoperatively and 3 months postoperatively...
April 11, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29624141/management-simulations-for-lean-healthcare-exploiting-the-potentials-of-role-playing
#5
Federico Barnabè, Maria Cleofe Giorgino, Jacopo Guercini, Caterina Bianciardi, Vincenzo Mezzatesta
Purpose The purpose of this paper is to investigate the potentials of role-playing (RP) both in training healthcare (HC) professionals to implement tools and improvement actions based on Lean principles, and in supporting group discussion and the sharing of different competencies for the development of Lean HC. Design/methodology/approach The paper presents the case study of an RP simulation called LEAN HEALTHCARE LAB, which is used to train HC professionals at Siena University Hospital. The paper reports and discusses the results of a specific two-day simulation session and of a questionnaire that was distributed to gather feedback from the participants...
April 9, 2018: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/29614993/impact-of-resistance-training-on-body-composition-and-metabolic-syndrome-variables-during-androgen-deprivation-therapy-for-prostate-cancer-a-pilot-randomized-controlled-trial
#6
Jacqueline K Dawson, Tanya B Dorff, E Todd Schroeder, Christianne J Lane, Mitchell E Gross, Christina M Dieli-Conwright
BACKGROUND: Prostate cancer patients on androgen deprivation therapy (ADT) experience adverse effects such as lean mass loss, known as sarcopenia, fat gain, and changes in cardiometabolic factors that increase risk of metabolic syndrome (MetS). Resistance training can increase lean mass, reduce body fat, and improve physical function and quality of life, but no exercise interventions in prostate cancer patients on ADT have concomitantly improved body composition and MetS. This pilot trial investigated 12 weeks of resistance training on body composition and MetS changes in prostate cancer patients on ADT...
April 3, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29596648/quantification-of-an-exercise-rehabilitation-program-for-severely-burned-children-the-standard-of-care-at-shriners-hospitals-for-children%C3%A2-galveston
#7
Eric Rivas, David N Herndon, Janos Cambiaso-Daniel, Victoria G Rontoyanni, Craig Porter, Shauna Glover, Oscar E Suman
Introduction: Currently, there are no clear guidelines for the implementation of rehabilitative exercise training (RET) in burned individuals. Therefore, we quantified the training logs for exercise intensity, frequency, and duration of 6 weeks of this program in order to develop a basic framework for outpatient RET in patients recovering from severe burns. Methods: Thirty-three children (11 female, [mean±SD] 12±3 years, 145±18 cm, 40±11 kg, 49±31 BMI percentile) with severe burns (49±15% total body surface area burned, with 35±22% third-degree burns) completed our 6-week resistance and aerobic exercise training program...
January 25, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29596612/burn-injury-may-have-age-dependent-effects-on-strength-and-aerobic-exercise-capacity-in-males
#8
Eric Rivas, Kevin Sanchez, Janos Cambiaso-Daniel, Ileana L Gutierrez, Joan Tran, David N Herndon, Oscar E Suman
Whether burn injury affects boys and men differently is currently unknown. To test the hypothesis that burned boys have lower exercise capacity and exercise training induced responses compared to burned men, forty young boys (12±4 years, 149±20 cm, 46±18 kg) were matched to 35 adult men (33±9 years, 174±10 cm, 84±16 kg) based on extent of burn injury (total body surface area burned, boys 46±14% vs. men 47±30, P=0.85) and length of hospital stay (boys 33±23 vs. men 41±32 days, P=0.23). Strength (peak torque) and cardiorespiratory fitness (peak VO2) were normalized to lean body mass for group comparisons...
December 8, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29589385/evolution-of-diabetes-care-in-hong-kong-from-the-hong-kong-diabetes-register-to-jade-pearl-program-to-ramp-and-pep-program
#9
REVIEW
Ivy H Y Ng, Kitty K T Cheung, Tiffany T L Yau, Elaine Chow, Risa Ozaki, Juliana C N Chan
The rapid increase in diabetes prevalence globally has contributed to large increases in health care expenditure on diabetic complications, posing a major health burden to countries worldwide. Asians are commonly observed to have poorer β-cell function and greater insulin resistance compared to the Caucasian population, which is attributed by their lower lean body mass and central obesity. This "double phenotype" as well as the rising prevalence of young onset diabetes in Asia has placed Asians with diabetes at high risk of cardiovascular and renal complications, with cancer emerging as an important cause of morbidity and mortality...
March 2018: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29587703/programming-and-supervision-of-resistance-training-leads-to-positive-effects-on-strength-and-body-composition-results-from-two-randomised-trials-of-community-fitness-programmes
#10
Steven Mann, Alfonso Jimenez, James Steele, Sarah Domone, Matthew Wade, Chris Beedie
BACKGROUND: Many sedentary adults have high body fat along with low fitness, strength, and lean body mass (LBM) which are associated with poor health independently of body mass. Physical activity can aid in prevention, management, and treatment of numerous chronic conditions. The potential efficacy of resistance training (RT) in modifying risk factors for cardiovascular and metabolic disease is clear. However, RT is under researched in public health. We report community-based studies of RT in sedentary (Study 1), and overweight and pre-diabetic (Study 2) populations...
March 27, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29569116/longitudinal-comparison-of-low-and-high-velocity-resistance-training-in-relation-to-body-composition-and-functional-fitness-of-older-adults
#11
Michelle Gray, Melissa Powers, Larissa Boyd, Kayla Garver
BACKGROUND: Functional mobility disability affects more than one in five adults over 70 years and increases to 80% by 90 years. While negative changes in mobility are multifactorial, deleterious body composition changes contribute significantly. Resistance training alters the negative trajectory of physical function as well as increases lean mass among older adults. Recently, high-velocity (HV) resistance training has been indicated as an effective intervention to increase lean mass and functional performance...
March 22, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29568109/mitochondrial-inefficiency-in-infants-born-to-overweight-african-american-mothers
#12
Manjusha Abraham, Christina A Collins, Scott Flewelling, Maraya Camazine, Alison Cahill, W Todd Cade, Jennifer G Duncan
BACKGROUND: Currently 20-35% of pregnant women are obese, posing a major health risk for mother and fetus. It is postulated that an abnormal maternal-fetal nutritional environment leads to adverse metabolic programming, resulting in altered substrate metabolism in the offspring and predisposing to risks of obesity and diabetes later in life. Data indicate that oocytes from overweight animals have abnormal mitochondria. We hypothesized that maternal obesity is associated with altered mitochondrial function in healthy neonatal offspring...
March 3, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29559726/collateral-fattening-in-body-composition-autoregulation-its-determinants-and-significance-for-obesity-predisposition
#13
REVIEW
Abdul G Dulloo, Jennifer L Miles-Chan, Yves Schutz
Collateral fattening refers to the process whereby excess fat is deposited as a result of the body's attempt to counter a deficit in lean mass through overeating. Its demonstration and significance to weight regulation and obesity can be traced to work on energy budget strategies in growing mammals and birds, and to men recovering from experimental starvation. The cardinal features of collateral fattening rests upon (i) the existence of a feedback system between lean tissue and appetite control, with lean tissue deficit driving hyperphagia, and (ii) upon the occurrence of a temporal desynchronization in the recovery of body composition, with complete recovery of fat mass preceeding that of lean mass...
March 20, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29556792/building-a-response-criterion-for-pediatric-multidisciplinary-obesity-intervention-success-based-on-combined-benefits
#14
Nelson Nardo Junior, Josiane Aparecida Alves Bianchini, Danilo Fernandes da Silva, Zachary M Ferraro, Carlos Andres Lopera, Vanessa Drieli Seron Antonini
To propose a response criterion for analyzing the intervention success by verifying patient outcomes after a multidisciplinary obesity treatment program in Brazilian children and adolescents. Obese children and adolescents (n = 103) completed a 16-week multidisciplinary intervention (IG) and were compared to the control group (CG) (n = 66). A cluster of parameters (e.g. total domain of HRQoL; BMI z-score; cardiorespiratory fitness; body mass; waist circumference; fat mass; lean mass) were measured pre and post-intervention, and the sum of the median percentage variation and the percentile 25 and 75 were used from IG and CG to determine the responsiveness to the program...
March 19, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29556158/calorie-restriction-regime-enhances-physical-performance-of-trained-athletes
#15
Victoria Pons, Joan Riera, Xavier Capó, Miquel Martorell, Antoni Sureda, Josep A Tur, Franchek Drobnic, Antoni Pons
Background: Caloric restriction induces mitochondrial biogenesis and improves physical fitness in rodents. We aimed to provide evidence of how caloric restriction affects the body composition and physical performance of trained athletes and to evaluate the possible impact of an every-other-day feeding diet on nutritional deficiencies of micronutrients and essential fatty acids. Methods: The study was performed with 12 healthy male athletes by carrying out a 33% caloric restriction with respect to their usual diet...
2018: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29548412/choice-of-precipitant-and-calcination-temperature-of-precursor-for-synthesis-of-nico-2-o-4-for-control-of-co-ch-4-emissions-from-cng-vehicles
#16
Suverna Trivedi, Ram Prasad
Compressed natural gas (CNG) is most appropriate an alternative of conventional fuel for automobiles. However, emissions of carbon-monoxide and methane from such vehicles adversely affect human health and environment. Consequently, to abate emissions from CNG vehicles, development of highly efficient and inexpensive catalysts is necessary. Thus, the present work attempts to scan the effects of precipitants (Na2 CO3 , KOH and urea) for nickel cobaltite (NiCo2 O4 ) catalysts prepared by co-precipitation from nitrate solutions and calcined in a lean CO-air mixture at 400°C...
March 2018: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/29548024/utilizing-lean-six-sigma-methodology-to-improve-the-authored-works-command-approval-process-at-naval-medical-center-san-diego
#17
Michelle M Valdez, Maureen Liwanag, Charles Mount, Rechell Rodriguez, Elisea Avalos-Reyes, Andrew Smith, David Collette, Michael Starsiak, Richard Green
Introduction: Inefficiencies in the command approval process for publications and/or presentations negatively impact DoD Graduate Medical Education (GME) residency programs' ability to meet ACGME scholarly activity requirements. A preliminary review of the authored works approval process at Naval Medical Center San Diego (NMCSD) disclosed significant inefficiency, variation in process, and a low level of customer satisfaction. In order to facilitate and encourage scholarly activity at NMCSD, and meet ACGME requirements, the Executive Steering Council (ESC) chartered an interprofessional team to lead a Lean Six Sigma (LSS) Rapid Improvement Event (RIE) project...
March 14, 2018: Military Medicine
https://www.readbyqxmd.com/read/29528397/a-genome-wide-association-study-of-growth-and-fatness-traits-in-two-pig-populations-with-different-genetic-backgrounds
#18
Y Jiang, S Tang, C Wang, Y Wang, Y Qin, Y Wang, J Zhang, H Song, S Mi, F Yu, W Xiao, Q Zhang, X Ding
Improvement in growth and fatness traits are the main objectives in pig all breeding programs. Tenth rib backfat thickness (10RIBBFT) and days to 100 kg (D100), which are good predictors of carcass lean content and growth rate, respectively, are economically important traits and also main breeding target traits in pigs. To investigate the genetic mechanisms of 10RIBBFT and D100 of pigs, we sampled 1,137 and 888 pigs from 2 Yorkshire populations of American and British origin, respectively, and conducted genome-wide association study (GWAS) through combined analysis and meta-analysis, to identify SNPs associated with 10RIBBFT and D100...
March 8, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29526840/feasibility-of-high-intensity-training-in-nonspecific-chronic-low-back-pain-a-clinical-trial
#19
Jonas Verbrugghe, Anouk Agten, Bert O Eijnde, Enzo Olivieri, Xavier Huybrechts, Henk Seelen, Frank Vandenabeele, Annick Timmermans
BACKGROUND: Although low to moderate intensity exercise therapy is a predominant part of rehabilitation in nonspecific chronic low back pain (NSCLBP), effect sizes are small and optimal exercise modalities/intensities are unclear. Conversely, effects of high intensity training have not yet been investigated in this population. OBJECTIVE: The aim of this study is to investigate the feasibility of high intensity training (HIT) and to explore the magnitude of the effects of a HIT program may have on exercise capacity and disease related outcome measures compared to conventional therapy for persons with NSCLBP...
March 2, 2018: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29516309/lifestyle-intervention-program-for-amelioration-of-dysmetabolism-in-overweight-women
#20
Aleksandra Kozłowska, Katarzyna M Okręglicka, Anna M Jagielska, Martyna Skibniewska, Aneta Nitsch-Osuch
Overweight and obesity, a cluster of multiple risk factors for atherosclerosis such as elevated blood pressure, elevated glucose level, and dyslipidemia, increase the risk of all-cause mortality and cardiovascular morbidity and mortality. Physical activity and a proper diet are essential preventive measures. The aim of the study was to evaluate the effects of a two-month intervention program consisting of a low-caloric diet (1,500 kcal) and increased physical activity on the anthropometric parameters, body composition, resting metabolic rate, and maximum oxygen uptake...
March 8, 2018: Advances in Experimental Medicine and Biology
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