keyword
https://read.qxmd.com/read/38496212/case-report-inflamed-jacobson-nerve-an-uncommon-cause-of-persisting-otalgia-after-an-acute-otitis-media
#21
Aybige Camurdan, Alexander Kilgue, Lars Uwe Scholtz, Ingo Todt
INTRODUCTION: Otalgia can have multiple causes. Mostly otalgia is caused by a tubal dysfunction or an acute middle ear infection. This case describes a patient with an inflammation of the Jacobson's nerve causing severe persistent otalgia after an acute otitis media. The patients complaints completely disappeared after neurolysis of the Jacobson's nerve. CASE PRESENTATION: We describe a case of a 21-year-old female caucasian patient with acute otitis media and persistent intractable otalgia...
2024: Frontiers in Surgery
https://read.qxmd.com/read/38496104/impact-of-chronic-suppurative-otitis-media-on-quality-of-life-and-psychological-well-being-a-cross-sectional-study
#22
JOURNAL ARTICLE
Shaila Sidam, Anjan K Sahoo, Utkal P Mishra, Vikas Gupta, Anuradha Kushwah, Prasanta K Sahoo
BACKGROUND: Chronic suppurative otitis media (CSOM) is a prevalent and persistent middle ear condition that not only affects auditory health but also potentially influences various aspects of an individual's life. This study explores the correlation between CSOM, depression, anxiety, and stress, using the 21-item Depression, Anxiety, and Stress Scale (DASS 21), also assessing quality of life (QoL) using the Chronic Ear Survey (CES) questionnaire. The primary objective of this study was to gather prospective audiological data along with information on both disease-specific quality of life and psychological well-being, utilizing validated measurement instruments...
February 2024: Curēus
https://read.qxmd.com/read/38493326/clinical-characteristics-etiology-and-outcomes-of-hypothermia-in-well-appearing-children-referred-to-the-emergency-department
#23
JOURNAL ARTICLE
Lea Ohana Sarna, Dina Qaraen Saloni, Mevaseret Avital, Naama Pines, Itai Gross, Giora Wieser, Saar Hashvya
BACKGROUND: Hypothermia, as a sign of serious bacterial infection (SBI) in children and infants older than 90 days is poorly characterized, especially in the post-pneumococcal vaccine era. OBJECTIVES: To assess the prevalence of SBI in children and infants presenting to the pediatric emergency department (PED) with reported or documented hypothermia. METHODS: Retrospective data analysis was conducted of all well-appearing children aged 0-16 years who presented with a diagnosis of hypothermia at two tertiary PEDs from 2010 to 2019...
March 2024: Israel Medical Association Journal: IMAJ
https://read.qxmd.com/read/38490712/reconstruction-of-an-obliterated-eustachian-tube-transnasal-lighted-guidewire-catheter-stenting
#24
JOURNAL ARTICLE
Victor Bor-Chang Hsue, Yu-Tung Wong, Arthur Wu, Dennis Tang
An obliterated Eustachian tube (ET) is a rare occurrence that can lead to chronic otitis media (OM) and aural fullness even with treatment. Our study presents a review of the literature on methods of stenting the ET. We additionally present a case of a man with mucoepidermoid carcinoma of the ET who underwent a radical nasal pharyngectomy with reconstruction and adjuvant radiation, and who had symptoms of intolerable otorrhea after tympanostomy tube placement to treat aural fullness and mucoid OM. We used a novel method of stenting the ET using a transnasal lighted guidewire catheter and steroid eluting stents placed along the entire medial ET...
March 15, 2024: BMJ Case Reports
https://read.qxmd.com/read/38490018/the-importance-of-mechanical-and-biological-cues-of-tympanic-membrane-grafts-to-ensure-optimal-regeneration
#25
JOURNAL ARTICLE
Oriana Nobus, Laurens Parmentier, Pieter Livens, Pieter Muyshondt, Krystyna Szewcyk, Christel Jacobs, Dorien Verdoodt, Leen Pieters, Quinten Thijssen, Bo Van Durme, Anne Vral, Joris Dirckx, Vincent Van Rompaey, Sandra Van Vlierberghe
Chronic suppurative otitis media (CSOM) is often associated with permanent tympanic membrane (TM) perforation and conductive hearing loss. The current clinical gold standard, using autografts and allografts, suffers from several drawbacks. Artificial replacement materials can help to overcome these drawbacks. Therefore, scaffolds fabricated through digital light processing (DLP) were herein created to support TM regeneration. Various UV-curable printing inks, including gelatin methacryloyl (GelMA), gelatin-norbornene-norbornene (GelNBNB) (crosslinked with thiolated gelatin (GelSH)) and alkene-functionalized poly-ε-caprolactone (E-PCL) (crosslinked with pentaerythritol tetrakis(3-mercaptopropionate) (PETA4SH)) were optimized regarding photo-initiator (PI) and photo-absorber (PA) concentrations through viscosity characterization, photo-rheology and the establishment of working curves for DLP...
March 11, 2024: Biomater Adv
https://read.qxmd.com/read/38487112/general-population-awareness-of-primary-immune-deficiency-disease-in-children-in-the-arar-region-saudi-arabia
#26
JOURNAL ARTICLE
Safya E Esmaeel, Hassan T Mohamed, Reef A Alshammari, Israa S Alanazi, Naseem D Aleawaili, Fai S Alanazi
Background Primary immunodeficiency disorders (PIDD) are of various types and severities, and they are associated with a delay in diagnosis. Early diagnosis of PIDD helps to improve the quality of life of affected children and prevent permanent consequences such as organ damage. Hence, awareness of PIDD is a must in the community to aid in early detection. Objectives The study aims to investigate the general population's awareness of PIDD in children in Arar, Northern Saudi Arabia. Methods A cross-sectional design was utilized to determine the awareness of PIDD in children in Arar, Northern Saudi Arabia...
February 2024: Curēus
https://read.qxmd.com/read/38486181/development-of-the-national-consensus-statement-on-ear-health-and-hearing-check-recommendations-for-aboriginal-and-torres-strait-islander-children-aged-under-6-years-attending-primary-care-systematic-scoping-review-and-e-delphi
#27
JOURNAL ARTICLE
Samantha Harkus, Vivienne Marnane, Isabel O'Keeffe, Carmen Kung, Meagan Ward, Neil Orr, John Skinner, Jessica Kate Hughes, Lose Fonua Wiradjuri, Michelle Kennedy Wiradjuri, Kelvin Kong Worimi, Mary Belfrage
BACKGROUND: Early detection of long-term, often asymptomatic, middle ear infection in young Aboriginal and Torres Strait Islander children is more likely to be achieved when ear health and hearing checks are routinely undertaken in primary healthcare. Evidence consistently demonstrates the adverse impacts of this condition on the development and wellbeing of children and their families. We aimed to develop feasible, evidence- and consensus-based primary healthcare recommendations addressing the components and timing of ear health and hearing checks for Aboriginal and Torres Strait Islander children aged under 6 years, not already known to have, nor being actively managed for, ear and hearing problems...
March 14, 2024: BMC Prim Care
https://read.qxmd.com/read/38485640/incidence-of-pneumococcal-disease-in-children-%C3%A2-48-months-old-in-the-united-states-1998-2019
#28
JOURNAL ARTICLE
Salini Mohanty, Nicolae Done, Qing Liu, Yan Song, Travis Wang, Katherine Gaburo, Eric M Sarpong, Meghan White, Jessica P Weaver, James Signorovitch, Thomas Weiss
BACKGROUND: Pneumococcal disease (PD) is a major cause of morbidity and mortality among children, particularly in the youngest age groups. This study aimed to assess the incidence of PD over time by age group in young children with commercial or Medicaid coverage in the US. METHODS: Episodes of invasive pneumococcal disease (IPD), all-cause pneumonia (ACP), and acute otitis media (AOM) were identified in the MarketScan® Commercial and Medicaid claims databases using diagnosis codes among children aged ≤ 48 months with confirmed date of birth (DoB), at any time during the study period (1998-2019)...
March 13, 2024: Vaccine
https://read.qxmd.com/read/38482959/chronic-suppurative-otitis-media-a-prospective-descriptive-study-of-the-microbiology-and-antimicrobial-susceptibility-patterns
#29
JOURNAL ARTICLE
Tessa K Suttle, Timothy Els, Julia Toman, Danielle Curtis, Rheese McNab, Anna Sizemore, Margaret Van Cleve, Richard A Brombacher
OBJECTIVE: This study aims to identify dominant causative pathogens of chronic suppurative otitis media (CSOM) and their antimicrobial susceptibility patterns. The secondary objective is to assess the cholesteatoma concurrence among this population. STUDY DESIGN: A prospective descriptive study. SETTING: Port Elizabeth Provincial Hospital, Eastern Cape, South Africa. METHODS: Aural swabs of purulent otorrhoea were collected from patients with CSOM attending the otorhinolaryngology outpatient department between April 2022 and June 2023...
March 14, 2024: Otolaryngology—Head and Neck Surgery
https://read.qxmd.com/read/38471705/pseudoparalysis-in-an-infant-with-otitis-media-an-evolving-presentation-of-scapular-osteomyelitis
#30
JOURNAL ARTICLE
Dominic Butler, Edina Moylett
A female infant presented to an Irish hospital with a 4-day history of fever, irritability and reduced oral intake. Initial inflammatory markers were significantly elevated, an erythematous tympanic membrane was noted on examination and an initial diagnosis of acute otitis media was made. By the third hospital day, the infant was noted to be irritable when being lifted up; pseudoparalysis of the right upper limb was observed. A radiograph of the right shoulder was normal; MRI identified acute scapular osteomyelitis with subperiosteal abscess formation...
March 12, 2024: BMJ Case Reports
https://read.qxmd.com/read/38470272/nasal-delivery-of-haemophilus-haemolyticus-is-safe-reduces-influenza-severity-and-prevents-development-of-otitis-media-in-mice
#31
JOURNAL ARTICLE
Naomi Scott, Kelly M Martinovich, Caitlyn M Granland, Elke J Seppanen, M Christian Tjiam, Camilla de Gier, Edison Foo, Kirsty R Short, Keng Yih Chew, Alma Fulurija, Deborah H Strickland, Peter C Richmond, Lea-Ann S Kirkham
BACKGROUND: Despite vaccination, influenza and otitis media (OM) remain leading causes of illness. We previously found that the human respiratory commensal Haemophilus haemolyticus prevents bacterial infection in vitro and that the related murine commensal Muribacter muris delays OM development in mice. The observation that M muris pretreatment reduced lung influenza titer and inflammation suggests that these bacteria could be exploited for protection against influenza/OM. METHODS: Safety and efficacy of intranasal H haemolyticus at 5 × 107 colony-forming units (CFU) was tested in female BALB/cARC mice using an influenza model and influenza-driven nontypeable Haemophilus influenzae (NTHi) OM model...
March 12, 2024: Journal of Infectious Diseases
https://read.qxmd.com/read/38465039/mastoiditis-now-affects-adults-a-case-report-of-an-occurrence-of-the-disease-in-an-82-year-old-male
#32
Nao Nakasato, Latha Ganti
Mastoiditis is typically considered a suppurative complication of otitis media seen in children. Vaccines and therapeutics can change the demographics of diseases. Childhood vaccination against Haemophilus influenza, for example, has shifted the mean age for ear, nose, and throat infections caused by this bug to age 25, whereas this used to be most prevalent in the pediatric age group previously. The authors present the case of an 82-year-old man who had mastoiditis. This case serves as a reminder to avoid anchoring bias when seeing an undifferentiated patient in the emergency department...
February 2024: Curēus
https://read.qxmd.com/read/38464759/investigating-the-epidemiological-relevance-of-secretory-otitis-media-and-neighboring-organ-diseases-through-an-internet-search
#33
JOURNAL ARTICLE
Cheng Guo, Linlin Pan, Ling Chen, Jinghua Xie, Zhuozheng Liang, Yongjin Huang, Long He
BACKGROUND: This study examined the epidemiological correlations between secretory otitis media (SOM) and diseases of neighboring organs. We measured changes in disease incidences during the 2020 COVID-19 pandemic using Internet big data spanning from 2011 to 2021. METHODS: This study used the Baidu Index (BI) to determine the search volume for the terms "secretory otitis media (SOM)", "tonsillitis", "pharyngolaryngitis", "adenoid hypertrophy (AH)", "nasopharyngeal carcinoma (NPC)", "nasal septum deviation (NSD)", "rhinosinusitis", "allergic rhinitis (AR)", and "gastroesophageal reflux disease (GERD)" in Mandarin from January 2011 to December 2021...
2024: PeerJ
https://read.qxmd.com/read/38455816/a-case-of-gemella-morbillorum-causing-multi-valvular-endocarditis
#34
Gabriel Panama, Adolfo Martinez, Majid Yavari, Andrew Geunwon Kim, George Abela
This is the case of a 31-year-old man with no significant past medical history who presented to the emergency department experiencing persistent fevers, chills, and malaise for the past 2-3 weeks. During this period, he had multiple urgent care visits for possible left-sided otitis media which was treated with short a course of Augmentin. While on antibiotics his symptoms would improve, but they would reappear once he had finished treatment. The patient also had significant dental carries with a chronic right molar infection...
February 2024: Curēus
https://read.qxmd.com/read/38455793/patulous-eustachian-tube-and-otitis-media-with-antineutrophil-cytoplasmic-antibody-associated-vasculitis-omaav
#35
Iori Kusaka, Ryoukichi Ikeda, Aya Katsura, Kiyoto Shiga
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a systemic necrotizing vasculitis that affects small to medium-sized vessels. We describe two cases of patulous Eustachian tube (PET) in patients with otitis media with ANCA-associated vasculitis (OMAAV). The two cases presented in this paper had previously been diagnosed with Eustachian tube (ET) stenosis, and both presented with bilateral aural fullness, with one also experiencing postnasal drip and hearing loss. Both patients experienced positive myeloperoxidase (MPO)-ANCA and negative proteinase 3 (PR3)-ANCA, and treatment for ANCA-associated vasculitis (AAV) resulted in a diagnosis of PET...
February 2024: Curēus
https://read.qxmd.com/read/38455393/over-investigation-and-overtreatment-in-pediatrics-a-survey-from-the-european-academy-of-paediatrics-and-japan-pediatric-society
#36
JOURNAL ARTICLE
Lina Jankauskaite, Corinne Wyder, Stefano Del Torso, Marina Mamenko, Sandra Trapani, Zachi Grossman, Adamos Hadjipanayis, Karin Geitmann, Hikoro Matsui, Akihiko Saitoh, Tetsuya Isayama, Nora Karara, Alessandra Montemaggi, Farhan Saleem Ud Din, Ketil Størdal
INTRODUCTION: Avoiding over-investigation and overtreatment in health care is a challenge for clinicians across the world, prompting the international Choosing Wisely campaign. Lists of recommendations regarding medical overactivity are helpful tools to guide clinicians and quality improvement initiatives. We aimed to identify the most frequent and important clinical challenges related to pediatric medical overactivity in Europe and Japan. Based on the results, we aim to establish a (European) list of Choosing Wisely recommendations...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38454294/bilateral-nontuberculous-mycobacterial-otitis-media-a-case-report
#37
JOURNAL ARTICLE
Riko Kajiwara, Kazuhisa Yamamoto, Shinya Ohira, Kota Wada
Established treatment strategies for nontuberculous mycobacterial (NTM) infections are currently lacking, and whether surgical treatment should be applied in combination with antibiotic therapy remains debatable. Here, we report a case of bilateral otitis media caused by Mycobacterium abscessusa, a highly antibiotic-resistant bacterium. Many reported cases of NTM otitis media are unilateral, in which hearing of the contralateral ear is preserved. In the present case, strategies to improve hearing outcomes were considered, as both ears were affected...
January 2024: Journal of International Advanced Otology
https://read.qxmd.com/read/38452739/evaluation-of-the-vestibulo-ocular-reflex-using-the-video-head-impulse-test-in-patients-with-unilateral-chronic-otitis-media
#38
JOURNAL ARTICLE
Gi-Sung Nam, Seunghyun Han, Sung Il Cho
OBJECTIVES: To evaluate the vestibulo-ocular reflex (VOR) using the video head impulse test (vHIT) as a vestibular function assessment method in patients with unilateral chronic otitis media (COM). METHODS: Twenty-eight patients with unilateral COM scheduled for middle ear surgery, including 12 males and 16 females with a mean age of 54.5 years, successfully underwent preoperative vHIT. vHIT variables, including VOR gain, VOR gain asymmetry, and the incidence of corrective saccades, were compared between the ipsilesional and contralesional ears...
March 7, 2024: Audiology & Neuro-otology
https://read.qxmd.com/read/38451449/bioequivalence-study-of-tebipenem-pivoxil-in-healthy-chinese-adults
#39
JOURNAL ARTICLE
Rui Hao, Yiming Shao, Sisi Lin, Yi Wu, Li Bian, Yiwen Zhang
BACKGROUND AND OBJECTIVE: Tebipenem pivoxil (TP) is a carbapenem and is applied against pneumonia, otitis media, and sinusitis. This study compared the pharmacokinetics (PK) and safety of a test (T) preparation and reference (R) preparation of TP in healthy Chinese adults. METHODS: This study was a single-center, randomized, open, single-dose (fasting/postprandial) oral administration, two-agent, two-sequence, two-cycle, crossover bioequivalence trial. A total of 60 participants were enrolled (24 fasting and 36 postprandial)...
March 7, 2024: Drugs in R&D
https://read.qxmd.com/read/38450789/racial-and-ethnic-disparities-in-otolaryngology-office-visit-and-tympanostomy-tube-placement-in-children-with-otitis-media
#40
JOURNAL ARTICLE
Yu Shi, Herbert C Heien, Laura J Orvidas, Lindsey R Sangaralingham, Moira Halbauer, David O Warner, Sean Phelan
OBJECTIVES: Racial disparities are pervasive in access to pediatric surgery. The goal of this study was to test the hypotheses that, compared with White children, non-White and Hispanic children: (1) were less likely to attend evaluations by otolaryngologists after a diagnosis of otitis media (OM) eligible for surgical referral, and (2) these children were less likely to receive tympanostomy tube (TT) after surgical consultation. METHODS: The OptumLabs Data Warehouse is a de-identified claims database of privately insured enrollees...
March 7, 2024: Laryngoscope
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