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https://www.readbyqxmd.com/read/28228126/hepatitis-c-virus-and-hiv-co-infection-among-pregnant-women-in-rwanda
#1
Mwumvaneza Mutagoma, Helene Balisanga, Dieudonné Sebuhoro, Aimable Mbituyumuremyi, Eric Remera, Samuel S Malamba, David J Riedel, Sabin Nsanzimana
BACKGROUND: Hepatitis C virus (HCV) infection is a pandemic causing disease; more than 185 million people are infected worldwide. An HCV antibody (Ab) prevalence of 6.0% was estimated in Central African countries. The study aimed at providing HCV prevalence estimates among pregnant women in Rwanda. METHODS: HCV surveillance through antibody screening test among pregnant women attending antenatal clinics was performed in 30 HIV sentinel surveillance sites in Rwanda...
February 22, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28225545/enhancing-political-will-for-universal-health-coverage-in-nigeria
#2
Bolaji S Aregbeshola
Universal health coverage aims to increase equity in access to quality health care services and to reduce financial risk due to health care costs. It is a key component of international health agenda and has been a subject of worldwide debate. Despite differing views on its scope and pathways to reach it, there is a global consensus that all countries should work toward universal health coverage. The goal remains distant for many African countries, including Nigeria. This is mostly due to lack of political will and commitment among political actors and policymakers...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28214925/missed-opportunities-in-neonatal-deaths-in-rwanda-applying-the-three-delays-model-in-a-cross-sectional-analysis-of-neonatal-death
#3
Efua Wilmot, Marcel Yotebieng, Alison Norris, Fidele Ngabo
Objective Administered in a timely manner, current evidence-based interventions could reduce neonatal deaths from infections, intrapartum injuries and complications due to prematurity. The three delays model (delay in seeking care, in arriving at a health facility, and in receiving adequate care), which has been applied to understanding maternal deaths, may be useful for understanding neonatal deaths. We assess the main causes of neonatal deaths in Rwanda and their associated delays. Methods Using a cross-sectional study design, we evaluated data from 2012 from 40 facilities in which babies were delivered...
February 18, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28188004/introducing-a-morbidity-and-mortality-conference-in-rwanda
#4
Egide Abahuje, Innocent Nzeyimana, Jennifer L Rickard
OBJECTIVES: To assess the structure, format, and educational features of a morbidity and mortality (M&M) conference in Rwanda. To determine factors associated with adverse events and to define opportunities for improvement. DESIGN: Retrospective, descriptive study of all cases presented at a surgical M&M conference over a 1-year period. Cases were reviewed for factors associated with adverse events and opportunities for improvement. Factors were characterized as delays in presentation, delays in diagnosis, delays in the operating room, errors in judgment, technical errors, advanced disease, and missing resources or malnutrition...
February 7, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28181083/environmental-impact-assessment-in-higher-education-institutions-in-east-africa-the-case-of-rwanda
#5
Telesphore Kabera
Due to the pressure on limited resources produced by a growing population and due to a decade of war, Rwanda is facing a major problem in environmental protection. Because of such problems, it seems only reasonable that environment-related courses should play an important role in the curricula of institutions of higher learning. The main aim of this research is to present a comprehensive picture of Environmental Impact Assessment (EIA) integration in graduate and undergraduate programs in Rwandese higher education institutions and to make recommendations for its improvement...
February 8, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28176645/prevention-interventions-for-people-living-with-hiv-in-military-settings
#6
Michael Grillo, Margo Sloan, Che Wankie, Kelly Woodland, Elizabeth Reader, Bruce Porter, Caroline Macera, Richard Shaffer
Military prevention programs and healthy living programs were developed in the mid-1980s to manage and support newly HIV-positive military personnel in the US military. Since then, a program developed by the Centers for Disease Control and Prevention with support from the Department of Defense HIV/AIDS Prevention Program (DHAPP), called Positive Health, Dignity and Prevention (PHDP), is currently being rolled out by DHAPP in partner militaries. The program, designed to reduce HIV transmission, is a package of interventions for people living with HIV (PLHIV), including risk reduction counseling, condom provision, disclosure counseling, testing of sexual partner(s) and children, adherence counseling, diagnosis and treatment of sexually transmitted infections, and provision of family planning services...
February 7, 2017: Current HIV Research
https://www.readbyqxmd.com/read/28169980/epidemiologic-characteristics-of-pediatric-trauma-patients-receiving-prehospital-care-in-kigali-rwanda
#7
Adam R Aluisio, Olivier Félix Umuhire, Gabin Mbanjumucyo, Naomi George, Alexis Kearney, Naz Karim, Jeanne DʼArc Nyinawankusi, Eric Uwitonze, Sam Enumah, John W Scott, Zeta Mutabazi, Georges Ntakiyiruta, Sudha Jayaraman, Robert Riviello, Jean Claude Byiringiro, Adam C Levine
BACKGROUND: Pediatric trauma is a significant public health problem in resource-constrained settings; however, the epidemiology of injuries is poorly defined in Rwanda. This study describes the characteristics of pediatric trauma patients transported to the emergency department (ED) of the Centre Hospitalier Universitaire de Kigali by emergency medical services in Kigali, Rwanda. METHODS: This cohort study was conducted at the Centre Hospitalier Universitaire de Kigali from December 2012 to February 2015...
February 4, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28166226/social-network-analysis-of-multi-stakeholder-platforms-in-agricultural-research-for-development-opportunities-and-constraints-for-innovation-and-scaling
#8
Frans Hermans, Murat Sartas, Boudy van Schagen, Piet van Asten, Marc Schut
Multi-stakeholder platforms (MSPs) are seen as a promising vehicle to achieve agricultural development impacts. By increasing collaboration, exchange of knowledge and influence mediation among farmers, researchers and other stakeholders, MSPs supposedly enhance their 'capacity to innovate' and contribute to the 'scaling of innovations'. The objective of this paper is to explore the capacity to innovate and scaling potential of three MSPs in Burundi, Rwanda and the South Kivu province located in the eastern part of Democratic Republic of Congo (DRC)...
2017: PloS One
https://www.readbyqxmd.com/read/28160992/the-history-and-evolution-of-anesthetic-care-in-rwanda
#9
Ramon F Martin, Charles Rangira, Jeanne d'Arc Uwambazimana, Sukumar P Desai
Although the development of anesthesia as a specialty and its practice in Rwanda have occurred postindependence, there are several contributing factors that have had an impact on the current state of the delivery of anesthetic care. European colonization of Africa, in general, and Belgium's control, in particular, are primary factors that have had a significant impact on education. The ripple effect has had a long-lasting impact on health care as well as other facets of present-day Rwandan society. Tertiary education did not start until the latter half of the 20th century and has left this country with the belated development of an educated population in sufficient numbers to handle health care problems and provide sufficient care to its population...
January 2017: Journal of Anesthesia History
https://www.readbyqxmd.com/read/28131049/iron-biofortified-staple-food-crops-for-improving-iron-status-a-review-of-the-current-evidence
#10
REVIEW
Julia L Finkelstein, Jere D Haas, Saurabh Mehta
Iron deficiency is the most common micronutrient deficiency globally and represents a major threat to public health. Biofortification, the process of enhancing micronutrient content and bioavailability in staple crops, represents an exciting sustainable food-based strategy to combat and prevent iron deficiency, particularly in resource-limited settings. In this review, we examine the evidence to date of the efficacy of iron-biofortified staple food crops on improving iron status in at-risk populations, including rice, pearl millet, and beans...
January 25, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/28130306/development-and-implementation-of-a-training-of-trainers-program-for-continuous-positive-airway-pressure-in-neonatal-and-pediatric-patients-in-five-low-and-middle-income-countries
#11
Patrick T Wilson, Megan M Benckert, Rachel T Moresky, Marilyn C Morris
We describe a pragmatic training-of-trainers program for the use of continuous positive airway pressure (CPAP) for neonatal and pediatric patients. The program is designed for medical professionals working in low- and middle-income countries and involves 2 days of in-class training followed by 1 day of in-service training. The program was created after training in Cambodia, Ghana, Honduras, Kenya and Rwanda and addresses the issues of resource availability, cultural context and local buy-in and partnership in low- and middle-income countries...
January 27, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28122655/a-comparative-study-of-psychotic-and-affective-symptoms-in-rwandan-and-kenyan-students
#12
A Owoso, S Jansen, D M Ndetei, A Musau, V N Mutiso, C Mudenge, A Ngirababyeyi, A Gasovya, D Mamah
AIMS: War and conflict are known to adversely affect mental health, although their effects on risk symptoms for psychosis development in youth in various parts of the world are unclear. The Rwandan genocide of 1994 and Civil War had widespread effects on the population. Despite this, there has been no significant research on psychosis risk in Rwanda. Our goal in the present study was to investigate the potential effects of genocide and war in two ways: by comparing Rwandan youth born before and after the genocide; and by comparing Rwandan and Kenyan adolescents of similar age...
January 26, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28081230/characteristics-of-hiv-infected-children-at-enrollment-into-care-and-at-antiretroviral-therapy-initiation-in-central-africa
#13
Adebola Adedimeji, Andrew Edmonds, Donald Hoover, Qiuhu Shi, Jean d'Amour Sinayobye, Martin Nduwimana, Patricia Lelo, Denis Nash, Kathryn Anastos, Marcel Yotebieng
BACKGROUND: Despite the World Health Organization (WHO) regularly updating guidelines to recommend earlier initiation of antiretroviral therapy (ART) in children, timely enrollment into care and initiation of ART in sub-Saharan Africa in children lags behind that of adults. The impact of implementing increasingly less restrictive ART guidelines on ART initiation in Central Africa has not been described. MATERIALS AND METHODS: Data are from the Central Africa International Epidemiologic Databases to Evaluate AIDS (IeDEA) pediatric cohort of 3,426 children (0-15 years) entering HIV care at 15 sites in Burundi, DRC, and Rwanda...
2017: PloS One
https://www.readbyqxmd.com/read/28078172/gastric-rupture-in-pregnancy-case-series-from-a-tertiary-institution-in-rwanda-and-review-of-the-literature
#14
David Ntirushwa, Stephen Rulisa, Febronie Muhorakeye, Lisa Bazzett-Matabele, Theogene Rurangwa, Maria Small
Background Gastric rupture is a rare, life-threatening condition during pregnancy. Case study We present three cases of gastric perforation during pregnancy and the puerperium. The first patient presented with gastric perforation 4 days following an uncomplicated cesarean delivery for obstetric indications. She initially complained of epigastric pain; however, those symptoms resolved. She later demonstrated worsening abdominal distension, intra-abdominal free fluid, and signs of peritonitis. At laparotomy, an ascariasis-associated gastric rupture was diagnosed...
October 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28077588/first-in-human-evaluation-of-the-safety-and-immunogenicity-of-an-intranasally-administered-replication-competent-sendai-virus-vectored-hiv-type-1-gag-vaccine-induction-of-potent-t-cell-or-antibody-responses-in-prime-boost-regimens
#15
Julien Nyombayire, Omu Anzala, Brian Gazzard, Etienne Karita, Philip Bergin, Peter Hayes, Jakub Kopycinski, Gloria Omosa-Manyonyi, Akil Jackson, Jean Bizimana, Bashir Farah, Eddy Sayeed, Christopher L Parks, Makoto Inoue, Takashi Hironaka, Hiroto Hara, Tsugumine Shu, Tetsuro Matano, Len Dally, Burc Barin, Harriet Park, Jill Gilmour, Angela Lombardo, Jean-Louis Excler, Patricia Fast, Dagna S Laufer, Josephine H Cox
BACKGROUND:  We report the first-in-human safety and immunogenicity assessment of a prototype intranasally administered, replication-competent Sendai virus (SeV)-vectored, human immunodeficiency virus type 1 (HIV-1) vaccine. METHODS:  Sixty-five HIV-1-uninfected adults in Kenya, Rwanda, and the United Kingdom were assigned to receive 1 of 4 prime-boost regimens (administered at 0 and 4 months, respectively; ratio of vaccine to placebo recipients, 12:4): priming with a lower-dose SeV-Gag given intranasally, followed by boosting with an adenovirus 35-vectored vaccine encoding HIV-1 Gag, reverse transcriptase, integrase, and Nef (Ad35-GRIN) given intramuscularly (SLA); priming with a higher-dose SeV-Gag given intranasally, followed by boosting with Ad35-GRIN given intramuscularly (SHA); priming with Ad35-GRIN given intramuscularly, followed by boosting with a higher-dose SeV-Gag given intranasally (ASH); and priming and boosting with a higher-dose SeV-Gag given intranasally (SHSH)...
January 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28056881/hepatitis-b-virus-strains-from-rwandan-blood-donors-are-genetically-similar-and-form-one-clade-within-subgenotype-a1
#16
Theogene Twagirumugabe, Gatare Swaibu, Timothy David Walker, Magnus Lindh, Jean Bosco Gahutu, Tomas Bergström, Heléne Norder
BACKGROUND: Rwanda is a central African country with about 12 million inhabitants. The 1994 genocide against the Tutsi destroyed much of the infrastructure, including the health system. Although this has improved significantly, many challenges remain to be addressed. In this study, the prevalence of serological markers of past and ongoing hepatitis B virus (HBV) infection and HBV vaccine related immunity was investigated in samples from blood donors from all regions of Rwanda. METHODS: The results from hepatitis B surface antigen (HBsAg) analyses of all (45,061) blood donations collected countrywide in 2014 from 13,637 first time and 31,424 repeat blood donors were compiled...
January 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28043604/the-majority-of-patients-with-multidrug-resistant-tuberculosis-in-sub-saharan-africa-present-a-concomitant-resistance-to-pyrazinamide
#17
Géraldine Daneau, Mourad Gumusboga, Pim De Rijk, Arnaud Trebucq, Leen Rigouts, Armand Van Deun, Bouke C de Jong
OBJECTIVE/BACKGROUND: Pyrazinamide (PZA) is an antibacterial used in the first-line regimen against tuberculosis (TB) for its action against dormant bacilli. PZA is also included in the new short regimen to treat multidrug-resistant TB (MDR-TB). However, the prevalence and significance of PZA resistance is not known in Central and West Africa. METHODS: Between 2013 and 2016, we collected samples from MDR-TB patients recruited in an observational study implementing the new short MDR-TB regimen in six countries: Burundi (n=35), Cameroon (n=135), Niger (n=57), Central African Republic (n=35), Democratic Republic of the Congo (n=99), and Rwanda (n=16)...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28025738/community-based-accompaniment-and-the-impact-of-distance-for-hiv-patients-newly-initiated-on-antiretroviral-therapy-early-outcomes-and-clinic-visit-adherence-in-rural-rwanda
#18
Fabien Munyaneza, Joseph Ntaganira, Laetitia Nyirazinyoye, Ermyas Birru, Marie Paul Nisingizwe, Neil Gupta, Cheryl L Amoroso, Guillaine Neza, Lisa R Hirschhorn, Bethany L Hedt-Gauthier
Community-based accompaniment (CBA) has been associated with improved antiretroviral therapy (ART) patient outcomes in Rwanda. In contrast, distance has generally been associated with poor outcomes. However, impact of distance on outcomes under the CBA model is unknown. This retrospective cohort study included 537 adults initiated on ART in 2012 in two rural districts in Rwanda. The primary outcomes at 6 months after ART initiation included overall program status, missed a visit and missed three consecutive visits...
December 26, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/28006001/detectable-viral-load-in-late-pregnancy-among-women-in-the-rwanda-option-b-pmtct-program-enrollment-results-from-the-kabeho-study
#19
Michelle M Gill, Heather J Hoffman, Emily A Bobrow, Placidie Mugwaneza, Dieudonne Ndatimana, Gilles F Ndayisaba, Cyprien Baribwira, Laura Guay, Anita Asiimwe
There are limited viral load (VL) data available from programs implementing "Option B+," lifelong antiretroviral treatment (ART) to all HIV-positive pregnant and postpartum women, in resource-limited settings. Extent of viral suppression from a prevention of mother-to-child transmission of HIV program in Rwanda was assessed among women enrolled in the Kigali Antiretroviral and Breastfeeding Assessment for the Elimination of HIV (Kabeho) Study. ARV drug resistance testing was conducted on women with VL>2000 copies/ml...
2016: PloS One
https://www.readbyqxmd.com/read/27988531/monophyly-review-six-new-species-and-dna-barcode-of-micropterous-afromontane-i-afropictinus-i-heteroptera-aradidae
#20
Ernst Heiss, Vasily Grebennikov
The micropterous East African flat bug genus Afropictinus Heiss, 1986 (Heteroptera: Aradidae: Mezirinae) is revised. In addition to the type and only known species A. congoensis (Hoberlandt, 1956) from Rwanda, four new species from Tanzania (A. castor sp. nov., A. hylas sp. nov., A. idas sp. nov., A. nauplius sp. nov.), one new species from the Democratic Republic of the Congo (A. kahuzianus sp. nov.), and one new species from Ethiopia (A. nabu sp. nov.) are described and illustrated. An identification key is presented to all seven nominal species of Afropictinus...
December 15, 2016: Zootaxa
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