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Lemierre

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https://www.readbyqxmd.com/read/28331642/lemierre-s-syndrome-associated-with-mechanical-ventilation-and-profound-deafness
#1
Lukas Birkner
Lemierre's syndrome is a rare disorder that is characterized by anaerobic organisms inducing a thrombophlebitis of the internal jugular vein (IJV) following a course of oropharyngeal infection. It often occurs in young and healthy patients. Clinicians continuously misinterpret early symptoms until infection disseminates systematically and life-threatening sepsis transpires. We report the case of a 58-year-old female developing Lemierre's syndrome accompanied by invasive ventilation support and a profound deafness requiring the implementation of a cochlear implant...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28260599/peritonsillar-abscess-clinical-aspects-of-microbiology-risk-factors-and-the-association-with-parapharyngeal-abscess
#2
REVIEW
Tejs Ehlers Klug
PTA is a collection of pus located between the tonsillar capsule and the pharyngeal constrictor muscle. It is considered a complication of acute tonsillitis and is the most prevalent deep neck infection (approximately 2000 cases annually in Denmark) and cause of acute admission to Danish ENT departments. Teenagers and young adults are most commonly affected and males may predominate over females. However, no studies of age- and gender-stratified incidence rates have previously been published. Furthermore, smoking may be associated with increased risk of peritonsillar abscess (PTA) development, although the magnitude of the association has not been estimated...
March 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28236587/lemierre-syndrome-in-an-adult-patient-with-fontan-circulation
#3
Andrés Carrillo López, Jaime Emilio Herrero Cereceda, Margarita Palmer Sans, María Esperanza Madrid Vergara, Cristina Royo Villa, María Araceli Molina Povedano
No abstract text is available yet for this article.
February 21, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28179705/the-forgotten-disease-lemierres-syndrome
#4
Ahmed Farhan, Yawar Ali Shah, Bushra Tariq Ali, Uzma Mumtaz, Umar Farooq
Lemierre's syndrome refers to septic thrombosis of deep veins of the neck, is a rare and often life threatening complication following upper respiratory tract infections. We present here a case of Lemierre's syndrome in a previously healthy 30 years old female who had a febrile illness for two weeks with associated dysphagia, hoarse voice and right sided neck swelling. She was investigated for retropharyngeal and parapharyngeal abscess, granulomatosis with polyangiitis, tuberculosis and thyroiditis but finally concluded as Lemierre's syndrome based on the findings of thrombosis of the deep neck veins following respiratory tract infection, septic pulmonary emboli and clinical recovery with antibiotics and supportive care...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28163049/fusobacterium-nucleatum-bacteremia-presenting-with-portal-vein-thrombosis-an-abdominal-lemierre-syndrome
#5
Joseph A Moore, Siayareh Rambally
No abstract text is available yet for this article.
February 3, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28150061/descending-necrotizing-mediastinitis-with-lemierre-s-syndrome
#6
Taisuke Kaiho, Takahiro Nakajima, Shuji Yonekura, Sawako Hamasaki, Takekazu Iwata, Ichiro Yoshino
Descending necrotizing mediastinitis is a severe infection of the mediastinum. Lemierre's syndrome manifests as thrombophlebitis in the cervical veins, which is caused by a neck infection. A 50-year-old woman had a fever with a 13-day history of neck pain. CT showed a deep neck abscess with vertebral vein thrombosis and mediastinal abscesses. Multiple small pulmonary nodules were found, suggesting septic pulmonary embolism. Emergency surgery for bilateral cervical and mediastinal drainage was performed, and antibiotics and anticoagulation agent was administered...
February 1, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28148337/bilateral-cavernous-sinus-thrombosis-in-lemierre-s-syndrome
#7
Adrian Budhram, Basavaraj Shettar, Donald H Lee, Michael Silverman, Kaveri Gupta
No abstract text is available yet for this article.
February 2, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/28122872/prevalence-of-fusobacterium-necrophorum-in-children-presenting-with-pharyngitis
#8
Tam T Van, Laura M Cox, Mike E Cox, Jennifer Dien Bard
Fusobacterium necrophorum, an obligate anaerobic bacterium, has recently been reported to be an important cause of bacterial pharyngitis with prevalence as high as group A Streptococcus (GAS) in adolescents and young adults. Importantly, F. necrophorum is the primary causative agent of the life-threatening Lemierre's syndrome and screening of pharyngeal samples may be warranted for early detection and prevention. The aim of this study was to determine the prevalence of F. necrophorum and groups A, C/G streptococci as agents of bacterial pharyngitis in children...
January 25, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28040511/fusobacterium-necrophorum-tonsillitis-with-mild-case-of-lemierre-s-syndrome
#9
Pavan Kumar Panchavati, Bhavini Kar, Ali Hassoun, Robert M Centor
No abstract text is available yet for this article.
December 28, 2016: Anaerobe
https://www.readbyqxmd.com/read/28006761/lemierre-syndrome-a-retrospective-study-of-the-role-of-anticoagulation-and-thrombosis-outcomes
#10
Margaret C Cupit-Link, Amulya Nageswara Rao, Deepti M Warad, Vilmarie Rodriguez
Lemierre syndrome (LS) is a multisystemic infection beginning in the oropharynx and leading to thrombosis of the internal jugular vein (IJV) with septic emboli and potential thrombotic extension to the central nervous system. Although patient outcomes have improved with early initiation of antimicrobial therapies, there is no consensus regarding the role of anticoagulation in LS. To better define the role of anticoagulation therapy in LS and determine whether anticoagulation improves thrombosis outcomes, we conducted a retrospective chart review of pediatric and adult patients diagnosed with LS and managed at our institution from January 1998 to December 2014...
2017: Acta Haematologica
https://www.readbyqxmd.com/read/27977559/methicillin-resistant-staphylococcus-aureus-as-a-cause-of-lemierre-s-syndrome
#11
Ravi H Jariwala, Swetha Srialluri, Maria Z Huang, Suresh B Boppana
Lemierre's syndrome (LS) or jugular vein suppurative thrombophlebitis is well described in literature. The organisms most often responsible are Fusobacterium necrophorum or anaerobic flora. We present a case of LS with an atypical microbiologic cause, methicillin-resistant Staphylococcus aureus. We also present retrospective review of all LS cases from our institution and identified 2 additional children with LS caused by methicillin-resistant S. aureus.
April 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27851613/1979-lemierre-syndrome-the-forgotten-disease
#12
Areeb Zamir, Daniel Schwed Lustgarten
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27834169/persistent-fever-with-chills-and-an-endocardial-mass-in-a-child-an-unusual-presentation-of-hughes-stovin-syndrome
#13
Marianna Fabi, Francesca Lami, Maurizio Zompatori
A 12-year-old boy with a right atrium endocardial mass was initially diagnosed as having Lemierre's syndrome on the basis of previous mastoiditis and jugular vein and cerebral venous thrombosis. Lack of response to antibiotics, persistent high fever with chills, acute-phase reactants, and peripheral arterial pseudoaneurysms made us reconsider the diagnosis. Only after the late appearance of radiological pulmonary lesions and recognition of pulmonary artery aneurysms, Hughes-Stovin syndrome was diagnosed. Hughes-Stovin syndrome is an exceedingly rare vasculitis, especially in childhood, consisting of multiple pulmonary artery aneurysms and deep venous thromboses...
November 11, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27797862/coexisting-pulmonary-haemorrhage-and-venous-thrombosis-a-tricky-but-novel-case
#14
Alexandra Fielding, Mira Pecheva, Aser Farghal, Russell Phillips
We present a case of Lemierre's disease complicated by pulmonary artery pseudoaneurysm. A previously well woman aged 43 years presented with a history of a sore throat and worsening dyspnoea. She was diagnosed with a severe cavitating bilateral pneumonia complicated by internal jugular vein thrombosis consistent with a diagnosis of Lemierre's disease. She had an episode of massive haemoptysis which was confirmed to be due to a pulmonary artery pseudoaneurysm which required radiologically guided embolisation...
October 20, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27737977/fusobacterium-infections-in-children
#15
Karen Arane, Ran D Goldman
QUESTION: A 2-year-old patient in my practice with acute otitis media that has progressed to mastoiditis with a high fever returns with positive culture results for Fusobacterium What should I do next? ANSWER: Fusobacterium is a genus of anaerobic bacteria. Although Fusobacterium infections are rare, they can become severe if not treated promptly. Appropriate treatment is combination antibiotic therapy consisting of a β-lactam (penicillin, cephalosporin) and an anaerobic antimicrobial agent (metronidazole, clindamycin)...
October 2016: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/27727258/-let-us-not-forget-the-lemierre-s-syndrome
#16
Stefano Cappanera, Beatrice Tiri, Lavinia M Saraca, Daniela Francisci
Lemierre's syndrome is a dangerous potential sequela of pharyngitis that results in septic thrombophlebitis of the internal jugular vein. A high index of suspicion is needed to consider this diagnosis in the workup of pharyngitis and should be aggressively treated once. Gram-negative anaerobic bacteria, mainly Fusobacterium necrophorum are implicated. Before the antibiotic era, Lemierre's syndrome was common and often fatal. But with the introduction of penicillin in the 1940s, the incidence of the syndrome dropped, and it eventually became known as the "forgotten disease"...
September 2016: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/27704629/fusobacterium-necrophorum-findings-in-denmark-from-2010-to-2014-using-data-from-the-danish-microbiology-database
#17
Steffen Bank, Anders Jensen, Hanne Merete Nielsen, Lena Hagelskjaer Kristensen, Marianne Voldstedlund, Jørgen Prag
Fusobacterium necrophorum findings in Denmark and estimation of the incidence of F. necrophorum bacteraemia was described using data from the nationwide Danish microbiology database (MiBa). All microbiological reports on any Fusobacterium species in Denmark were extracted for a period of 5 years from 2010 to 2014 from MiBa and from the local department of clinical microbiology. The overall incidence of F. necrophorum bacteraemia from 2010 to 2014 was 2.8 cases per million/year vs 9.4 in the age group 15-24 years...
December 2016: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/27695351/lemierre-s-syndrome-current-perspectives-on-diagnosis-and-management
#18
REVIEW
Katrine M Johannesen, Uffe Bodtger
This is a systematic review of cases with Lemierre's syndrome (LS) in the past 5 years. LS is characterized by sepsis often evolving after a sore throat or tonsillitis and then complicated by various septic emboli and thrombosis of the internal jugular vein. Symptoms include sepsis, pain, and/or swelling in the throat or neck, as well as respiratory symptoms. Laboratory findings show elevated infectious parameters and radiological findings show thrombosis of the internal jugular vein and emboli in the lungs or other organs...
2016: Infection and Drug Resistance
https://www.readbyqxmd.com/read/27693542/the-role-of-fusobacterium-necrophorum-in-pharyngotonsillitis-a-review
#19
REVIEW
Karin Holm, Steffen Bank, Hanne Nielsen, Lena Hagelskjær Kristensen, Jørgen Prag, Anders Jensen
Fusobacterium necrophorum is a gram-negative anaerobic bacterium that is the causative agent of the invasive disease Lemierre's syndrome. In addition, it is also associated with peritonsillar abscess formation and otitis media in small children. Recent research has shown that F. necrophorum may be involved in pharyngotonsillitis especially in adolescent and young adults and that it may be the second most common bacterial cause of pharyngotonsillitis after Streptococcus pyogenes (Group A streptococci). Peritonsillar abscesses and Lemierre's syndrome due to F...
December 2016: Anaerobe
https://www.readbyqxmd.com/read/27497400/to-anticoagulate-controversy-in-the-management-of-thrombotic-complications-of-head-neck-infections
#20
Jenna Rebelo, Smriti Nayan, Karen Choong, Martha Fulford, Anthony Chan, Doron D Sommer
OBJECTIVE: To review the thrombotic complications of head and neck infections, including Lemierre's syndrome, and their management. METHODS: A retrospective review of pediatric patients presenting to McMaster Children's Hospital from 2009 to 2013 was undertaken. The literature was reviewed for evidence regarding the use of anticoagulation therapy in this population. RESULTS: Eleven cases (6 males, 5 females) were identified. The median age was 10...
September 2016: International Journal of Pediatric Otorhinolaryngology
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