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Lemierre

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https://www.readbyqxmd.com/read/29123565/lemierre-s-syndrome-a-rare-cause-of-disseminated-sepsis-requiring-multi-organ-support
#1
John Rae, Katie Misselbrook
Lemierre's syndrome is a rare complication of acute pharyngitis characterised by septicaemia with infective thrombophlebitis of the internal jugular vein, most commonly due to Fusobacterium necrophorum. It characteristically affects healthy young adults causing persistent pyrexia and systemic sepsis presenting several days after an initial pharyngitis. Septic emboli seed via the bloodstream to distant sites including the lung, joints, skin, liver, spleen and brain. Prolonged antimicrobial therapy is required and admission to intensive care common...
November 2017: J Intensive Care Soc
https://www.readbyqxmd.com/read/29072873/not-just-a-simple-sore-throat
#2
Olivia Jones, Aram Salehi
The presentation of a 'sore throat' is common and often requires only symptomatic treatment. This is the case of a 20-year-old female who presented with persistent symptoms of a sore throat. On admission she had raised inflammatory markers and a subsequent blood culture demonstrated a fusobacterium necrophorum and arcanobacterium haemolyticum bacteraemia. Further investigations established an internal jugular vein thrombosis, confirming the diagnosis of Lemierre's syndrome. This case highlights the importance of further investigation when a sore throat fails to improve, and to remember this often-forgotten syndrome...
2017: Acute Medicine
https://www.readbyqxmd.com/read/29070428/lemierre-syndrome-after-tonsillectomy
#3
Daniel R Quast, Tanja A Lotz, Thomas G K Breuer
No abstract text is available yet for this article.
October 6, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29054895/lemierre-s-syndrome-variant-of-the-gut
#4
Thomas E Mellor, Natalie Mitchell, Jessica Logan
Infectious suppurative thrombophlebitis of the portal venous system, referred to as pylephlebitis, is a rare complication of intra-abdominal inflammatory processes. Advances in diagnostics and antibiotics have improved survival, but mortality remains remarkably high even in the most recent literature. The majority of patients have concomitant bacteraemia on presentation most commonly with typical gastrointestinal (GI) organisms. On rare occasion, patients have culture positive Fusobacterium, which has recently been associated with occult GI and genitourinary malignancies...
October 20, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29046755/some-neck-swellings-are-serious-a-case-of-lemierre-s-syndrome
#5
Ali Raza Ghani, Mohsin Hamid, Ahsan Raza, Rizwan Naseer, Joseph Crocetti
Lemierre's syndrome also termed post-anginal septicemia, is a disease characterized by internal jugular septic thrombophlebitis leading to Fusobacterium septicemia with multiple metastatic foci following an oropharyngeal infection. Diagnosis and management is challenging and can result in fatal consequences due to potential multisystem involvement and multiple complications. We describe here a case of Lemierre's syndrome with multifocal pneumonia, acute renal failure and protracted course of illness over forty days with successful recovery...
October 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29040036/septic-thrombosis-of-cavernous-sinus-extended-to-the-ipsilateral-internal-jugular-vein-and-transversal-sinus-with-favorable-outcome-clinical-and-radiological-features-of-a-lemierre-syndrome
#6
Arnaud Martel
An 86-year-old patient was hospitalized for fever and left acute orbital syndrome (red eye with moderate visual impairment, chemosis, ophthalmoplegia without proptosis, or any fundus involvement). CT scan showed superior ophthalmic vein and cavernous sinus enlargement complicating ipsilateral sphenoidal sinusitis. Magnetic resonance imaging (MRI) demonstrated the left cavernous sinus thrombosis extended to the ipsilateral jugular vein and transversal sinus (Lemierre syndrome). Intravenous broad-spectrum antibiotics and curative anticoagulation were prescribed...
October 17, 2017: Orbit
https://www.readbyqxmd.com/read/28918841/epidural-abscess-in-lemierre-s-syndrome
#7
Christina M Meade, Valeria D Cantos, Hachem Nasri, Mara Serbanescu, Evan J Anderson
No abstract text is available yet for this article.
September 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28879094/vertebral-osteomyelitis-as-a-rare-manifestation-of-lemierre-s-syndrome
#8
Takahiro Matsuo, Nobuyoshi Mori, Aki Sakurai, Yumiko Mikami, Keiichi Furukawa
No abstract text is available yet for this article.
2017: IDCases
https://www.readbyqxmd.com/read/28877155/lemierre-s-syndrome-presenting-as-multifocal-pyomyositis-in-a-young-child
#9
Melissa R Held, Hannah Kotler, Hannah Sneller, Catherine B Sullivan
Lemierre's syndrome is more common in young adults and the majority of patients present with pharyngitis. Multifocal pyomyositis is very rare in this setting and in young children. We present here a case of multifocal pyomyositis caused by Fusobacterium sp. in a young child. Fusobacterium should be considered in the differential diagnosis of multifocal pyomyositis of unclear etiology.
September 5, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28835825/lemierre-s-syndrome-necrotizing-pneumonia-and-staphylococcal-septic-shock-treated-with-extracorporeal-life-support
#10
Adrian C Mattke, Sudesh Prabhu, Julia Clark, Robert Labrom, Hanna Burns, Luregn J Schlapbach
OBJECTIVES: Lemierre's syndrome cause by methicillin-sensitive Staphylococcus aureus is rare, but can lead to necrotizing pneumonia and septicaemia. When treating such patient with extracorporeal life support source control can be both challenging and controversial. METHODS: In this report we present a 12 year old male who presented with Lemierre's syndrome from which he developed septic shock and severe necrotizing pneumonia. He also showed multiple pulmonary embolisms from the internal jugular vein thrombi, resulting in acute respiratory distress syndrome...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28822361/lemierre-s-syndrome-more-than-just-a-sore-throat
#11
Jenny M Held, Matthew L Leatherman, Robert L Ricca
No abstract text is available yet for this article.
August 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28808620/lemierre-s-syndrome-case-report-and-brief-literature-review
#12
Andrew Zhao, Mohammed Samannodi, Muhammad Tahir, Sarah Bensman, Michael Hocko
Lemierre's syndrome has been shown to be increasing in incidence in the past 20 years with one popular suggesting that said rise occurred from less aggressive antibacterial coverage. We report a case of Lemierre's syndrome and also reviewed the 15 most recent case reports. A previously healthy 25 year old male who initially developed sore throat and flu-like symptoms, was prescribed antibacterials as an outpatient but was hospitalized for worsening symptoms. He was later diagnosed with Lemierre's syndrome and improved clinically with IV antimicrobials alone...
2017: IDCases
https://www.readbyqxmd.com/read/28776174/utility-of-pet-scan-in-diagnosis-and-monitoring-descending-necrotizing-mediastinitis-complicating-lemierre-s-syndrome
#13
Tiziana Carandini, Virgilio Longari, Paolo Mendogni, Michele Gaffuri, Elisa Ceriani
No abstract text is available yet for this article.
August 3, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28754755/bacteraemia-and-liver-abscess-due-to-fusobacterium-necrophorum
#14
Rafael García Carretero, Marta Lopez-Lomba, Oscar Vazquez-Gomez, Belen Rodriguez-Maya
Fusobacterium necrophorum is the oropharyngeal pathogen usually associated with Lemierre's syndrome, a pharyngeal infection which evolves to sepsis, septic emboli and thrombophlebitis of the adjacent neck vessels. It is an uncommon causative bacteria of a liver abscess, and an extensive workup should, therefore, be performed in order to rule out potential sources of the infection. This case report describes the workup that led to the diagnosis of a colorectal carcinoma, which was deemed to be the source of the Fusobacterium bacteraemia...
July 27, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28736715/a-case-of-liver-abscess-and-fusobacterium-septicemia
#15
Elham Rahmati, Rosemary C She, Brittany Kazmierski, P Jan Geiseler, Darren Wong
Fusobacterium species are well described as the causative pathogen in Lemierre's syndrome, a suppurative thrombophlebitis of the jugular vein. However, they are less recognized for a unique variant of Lemierre's syndrome presenting with invasive intraabdominal infection and associated portal vein thrombosis. We describe a case of Fusobacterium nucleatum with hepatic abscess and septic pylephlebitis.
2017: IDCases
https://www.readbyqxmd.com/read/28719983/neonatal-lemierre-syndrome-youngest-reported-case-and-literature-review
#16
Blake S Raggio, Maria C Grant, Kimsey Rodriguez, Patrick J Cripe
A previously healthy 5-week-old female was admitted for sepsis secondary to methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. After several days of hospitalization, she experienced acute decompensation in mental status despite having received targeted antibiotic therapy. Imaging revealed left peritonsillar/parapharyngeal space abscess, left venous thrombophlebitis of the internal jugular vein, and septic emboli of the lungs and brain consistent with Lemierre syndrome. Bedside needle aspiration of the parapharyngeal abscess confirmed MRSA involvement...
July 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28651067/necrotizing-lip-infection-causing-septic-thrombophlebitis-of-the-neck-a%C3%A2-rare-variant-of-lemierre-syndrome
#17
Karl Cuddy, Nariman Saadat, Baber Khatib, Ashish Patel
Lemierre syndrome is an uncommon condition in which internal jugular vein thrombosis presents after recent oropharyngeal infection. Frequently, this is accompanied by septic emboli. This report outlines a variant of this disease process, with septic thrombophlebitis of the neck associated with a necrotizing skin infection of the lower lip and chin. A 25-year-old man with lower lip and chin swelling, initially managed with intravenous antibiotics, progressed to the development of a left facial vein thrombus, septic emboli to the lungs, and a necrotizing lower lip and chin infection that was managed with debridement, thrombectomy, and prolonged hemodynamic and pulmonary support...
June 2, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28646962/the-long-shadow-of-lemierre-s-syndrome
#18
Joshua Osowicki, Sarah Kapur, Linny Kimly Phuong, Simon Dobson
Lemierre's syndrome is a rare and feared complication of pharyngitis, occurring most commonly in adolescents and young adults. It is typically defined by the constellation of septic internal jugular vein thrombophlebitis, pulmonary and other septic emboli, and sterilesite infection by Fusobacterium necrophorum. The rarity and severity of Lemierre's syndrome has made it an attractive subject for case reports but there is a paucity of evidence to inform areas of persistent uncertainty. In recent years, heightened attention and controversy has focused upon speculation that a purported rise in the incidence of Lemierre's syndrome is due to reduced antibiotic prescribing for respiratory tract infections, that F...
June 2017: Journal of Infection
https://www.readbyqxmd.com/read/28633639/fusobacterial-liver-abscess-a-case-report-and-review-of-the-literature
#19
REVIEW
Dilip Jayasimhan, Linus Wu, Paul Huggan
BACKGROUND: Fusobacteriae are facultative anaerobic gram-negative bacilli which cause a range of invasive infections, amongst which pyogenic liver abscesses are rare. We describe a case of Fusobacterium nucleatum liver abscess and review the relevant literature. CASE PRESENTATION: A 51-year-old lady presented with a 4-day history of abdominal pain, diarrhoea, fever, rigors, and lethargy. Imaging revealed an abscess which was drained. Cultures of the blood and abscess aspirate grew Fusobacterium nucleatum and Prevotella pleuritidis respectively...
June 20, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28580216/septic-thrombophlebitis-of-the-internal-jugular-vein-a-case-of-lemierre-s-syndrome
#20
Adam Alperstein, Raymond M Fertig, Matthew Feldman, Daniel Watford, Susan Nystrom, Guesly Delva, Salman Muddassir
An 18-year-old gentleman with a history of recurrent tonsillitis presented to the emergency room complaining of worsening sore throat. He was found to have a peritonisillar abscess, and imaging revealed a non-occlusive left internal jugular vein thrombosis. Lemierre's syndrome is a rare, potentially fatal condition characterized by internal jugular vein thrombosis with septicemia following an acute oropharyngeal infection. While anticoagulation is the mainstay of treatment of deep venous thromboembolism (DVT) and pulmonary embolism (PE), the use of therapy is controversial in septic thrombophlebitis...
May 2017: Intractable & Rare Diseases Research
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