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Lemierre

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https://www.readbyqxmd.com/read/29705735/lemierre-s-syndrome-a-rare-cause-of-sepsis-presenting-with-an-absence-of-throat-symptoms
#1
Thomas Whittle, Natasha Amiraraghi, Bappa Sarkar
A 16-year-old boy presented to hospital with a 6-day history of diarrhoea, vomiting and abdominal pain. During his admission he was found to be hypotensive, tachycardic and persistently feverish. Blood cultures taken on admission isolated Fusobacterium necrophorum CT scanning of his neck showed a non-occlusive thrombus of the right internal jugular vein and a small right parapharyngeal abscess. CT scans of the chest and abdomen revealed multiple pulmonary abscesses, bilateral pleural effusions and splenomegaly...
April 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29669776/lemierre-s-syndrome-cavitary-lung-disease-caused-by-uncommon-bacteria
#2
Parmjyot Singh, Ajay Adial, Jack Mann, Asma Iftikhar
No abstract text is available yet for this article.
April 18, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29657730/lemierre-s-syndrome-presented-with-acute-pancreatitis
#3
Laura Garcia, Kaori Ito
Case: Lemierre's syndrome is a rare clinical condition that is characterized by infected internal jugular vein thrombosis with metastatic septicemia. The most common causative agent is Fusobacterium necrophorum . A previously healthy 37-year-old woman presented to our emergency department with nausea, vomiting, and diarrhea. She was admitted to the general practice unit with a diagnosis of acute pancreatitis then was subsequently transferred to the intensive care unit due to shock. Physical examination revealed tenderness on right side of the neck...
April 2018: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29616359/liver-abscess-due-to-fusobacterium-species-detected-on-ultrasonography-a-case-report
#4
Vasanthapriya Subramaniyam, Akiko Saito, Katsutoshi Tokushige
An oral infection harboring Fusobacterium species can gain entrance to the liver via hematogenous spread in the form of septic embolus, and can thereby cause abscesses. Such spread, described as Lemierre syndrome, is life threatening. We present such a case history of a man in his mid-40s, who presented with infection and Fusobacterium liver abscess with an acute fulminant disease course. The initial diagnosis was arrived at by ultrasound imaging and blood investigations. He was treated with antibiotics, ultrasound-guided liver abscess drainage, and extraction of the infected molar tooth...
April 3, 2018: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29573596/lemierre-s-syndrome-following-perianal-abscess-a-case-report
#5
Qusai Aljarrah, Yara Khazaleh, Mooath Al-Jarrah, Jordan W Oldbury, Ahmad K Abou-Foul
INTRODUCTION: Lemierre's syndrome (LS) is a rare and life-threatening condition characterized by suppurative thrombophlebitis of the internal jugular vein (IJV), and a history of head and neck (H&N) sepsis. LS is usually caused by Fusobacterium necrophorum, which is part of the normal flora in the oro-pharynx, and the digestive and urogenital tracts. We here report the first case of LS following perianal sepsis. PRESENTATION OF CASE: A 60-year-old man with a painful left neck swelling, dysphagia and worsening sepsis was referred from a peripheral unit where he had an incision and drainage of a perianal abscess a week earlier...
March 16, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29531456/a-case-of-lemierre-s-syndrome-in-intensive-care-unit
#6
Man-Yee Man, Hoi-Ping Shum, Wing-Wa Yan, Susanna K P Lau
We report a 21-year-old young male with Lemierre's syndrome presented as tonsillitis and Fusobacterium septicemia with respiratory failure and required intensive care. Lemierre's syndrome is the septic embolic complication of recent pharyngeal illness. Fusobacterium spp. accounts for the majority of cases. High index of suspicion is needed and prolonged antibiotic is advised. It is seldom seen in intensive care but should never be forgotten.
February 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29523424/clinical-mimics-an-emergency-medicine-focused-review-of-streptococcal-pharyngitis-mimics
#7
Michael Gottlieb, Brit Long, Alex Koyfman
BACKGROUND: Pharyngitis is a common disease in the emergency department (ED). Despite a relatively low incidence of complications, there are many dangerous conditions that can mimic this disease and are essential for the emergency physician to consider. OBJECTIVE: This article provides a review of the evaluation and management of group A β-hemolytic Streptococcal (GABHS) pharyngitis, as well as important medical conditions that can mimic this disease. DISCUSSION: GABHS pharyngitis often presents with fever, sore throat, tonsillar exudates, and anterior cervical lymphadenopathy...
May 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29436449/lesson-of-the-month-1-lemierre-s-syndrome-a-reminder-of-the-forgotten-disease
#8
Vivek Vijay, Zozik Fattah
Lemierre's syndrome is a condition characterised by suppurative thrombophlebitis of the internal jugular (IJ) vein following a recent oropharyngeal infection, with resulting septicaemia and metastatic lesions. It is strongly associated with Fusobacterium necrophorum, a Gram-negative bacilli. Key to early diagnosis is awareness of the classical history and course of this illness, and therefore to ask about a history of recent oropharyngeal infections when a young patient presents with fever and rigors. Diagnosis can be confirmed by showing thrombophlebitis of the IJ vein, culturing F necrophorum from normally sterile sites or demonstrating metastatic lesions in this clinical setting...
February 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29406559/lemierres-syndrom-%C3%A2-en-p%C3%A3-minnelse-om-%C3%A2-den-gl%C3%A3-mda-sjukdomen%C3%A2-god-kunskap-under-hela-v%C3%A3-rdkedjan-viktigt-f%C3%A3-r-att-i-tid-v%C3%A3-cka-misstanke
#9
Jan Hedenmark, Karin Holm, Fredrik Moberger, Erik Torell
The purpose of this case report and discussion is to heighten the awareness of Lemierres syndrome (postanginal sepsis).  Affected patients present in various fields of medicine and an increased incidence of "the forgotten disease" may be expected. Fusobacterium necrophorum is the most common pathogen. The clinical course includes a primary head or neck infection with thrombosis of the internal jugular vein with subsequent septic pulmonary embolization. The syndrome bears considerable morbidity and even mortality...
February 2, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29389826/complicated-fusobacterium-sinusitis-a-case-report
#10
Saloni P Sheth, Paul Ilkanich, Blaise Congeni
Fusobacterium infections and Lemierre Syndrome are traditionally associated with pharyngitis. We report three cases of Fusobacterium sinusitis that resulted in Pott Puffy Tumor. One of these cases also had Lemierre Syndrome. We encourage expansion of the clinical spectrum of Lemierre Syndrome to include complicated Fusobacterium sinusitis.
January 31, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29351278/analysis-of-the-tonsillar-microbiome-in-young-adults-with-sore-throat-reveals-a-high-relative-abundance-of-fusobacterium-necrophorum-with-low-diversity
#11
T Prescott Atkinson, Robert M Centor, Li Xiao, Fuchenchu Wang, Xiangqin Cui, William Van Der Pol, Casey D Morrow, Amy E Ratliff, Donna M Crabb, Arthur H Totten, Carlos A Estrada, Michael B Faircloth, Ken B Waites
Fusobacterium necrophorum (Fn), a gram-negative anaerobe, is increasingly implicated as an etiologic agent in older adolescents and young adults with sore throat. Inadequately treated Fn pharyngitis may result in suppurative complications such as peritonsillar abscess and Lemierre's syndrome. Data from the literature suggest that the incidence of life-threating complications in these age groups from Fn pharyngitis (Lemierre's syndrome) in the United States exceeds those associated with group A beta-hemolytic streptococcal (GAS) pharyngitis (acute rheumatic fever)...
2018: PloS One
https://www.readbyqxmd.com/read/29302305/lemierre-syndrome-a-diagnostic-dilemma-in-paediatric-patients
#12
Fatemeh Rafati, Vishal Bhalla, Varun Chillal, Mani Thyagarajan
Lemierre's syndrome is a rare disease of the head and neck, characterized by an initial infection, usually within the oropharynx, which can develop into a septic thrombophlebitis. It can involve the jugular vein, facial veins and respiratory tract. A 7-year-old child attended our institution with a 1-week history of fever and cough. Initial imaging demonstrated a large left sided empyema with multiple cavitating lung lesions and persisting pneumothoraces secondary to the development of a bronchopleural fistula...
December 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29298792/lemierre-s-syndrome-a-pain-in-the-neck-with-far-reaching-consequences
#13
Thomas James Stubington, Paul James
Lemierre's syndrome is a potentially life-threatening consequence of oropharyngeal and ear infections and often results in critical care admission and even intubation. Due to the multisystem manifestation, multiple teams may initially be involved in the care, some of which may be unfamiliar with the features and usual clinical course. This report describes a case in a 36-year-old woman with the classic features of internal jugular vein thrombosis and septic emboli to the lungs secondary to an oropharyngeal infection...
January 3, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29275396/variant-of-lemierre-s-syndrome-with-internal-jugular-vein-aneurysm
#14
Siew Houy Chua, Sidney Ching Liang Ong, Yuan Hwen Liew
Internal jugular vein (IJV) aneurysm is a rare entity, and a thrombosed aneurysm poses diagnostic and management challenges. We came across a 53-year-old woman who presented with fever, vomiting and right neck swelling for a week. Laboratory investigations showed neutrophilic leucocytosis, raised acute phase reactant and blood culture yielded Klebsiella pneumoniae Ultrasound and contrast-enhanced CT neck revealed a large fusiform aneurysm of the right IJV with filling defect extending from the aneurysm into the right transverse sinus...
December 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29204301/human-infection-with-fusobacterium-necrophorum-without-jugular-venous-thrombosis-a-varied-presentation-of-lemierre-s-syndrome
#15
Muhammad Asim Rana, Yashwant Kumar, Abdullah Ali Lashari, Ahmed F Mady
Lemierre's syndrome is also known as postangina septicemia, which is commonly caused by Fusobacterium necrophorum also known as Necrobacillus and also by other microorganisms like Staphylococcus , Streptococcus , Peptostreptococcus , and Bacteroides . Though the disease starts as an upper respiratory tract infection, it may spread and cause thrombophlebitis of the internal jugular vein. It may present itself through cranial nerve palsy or sepsis involving distant organs like the lungs or bones. It is also known as forgotten disease because of its rarity...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29123565/lemierre-s-syndrome-a-rare-cause-of-disseminated-sepsis-requiring-multi-organ-support
#16
John Rae, Katie Misselbrook
Lemierre's syndrome is a rare complication of acute pharyngitis characterised by septicaemia with infective thrombophlebitis of the internal jugular vein, most commonly due to Fusobacterium necrophorum . It characteristically affects healthy young adults causing persistent pyrexia and systemic sepsis presenting several days after an initial pharyngitis. Septic emboli seed via the bloodstream to distant sites including the lung, joints, skin, liver, spleen and brain. Prolonged antimicrobial therapy is required and admission to intensive care common...
November 2017: Journal of the Intensive Care Society
https://www.readbyqxmd.com/read/29072873/not-just-a-simple-sore-throat
#17
Olivia Jones, Aram Salehi
The presentation of a 'sore throat' is common and often requires only symptomatic treatment. This is the case of a 20-year-old female who presented with persistent symptoms of a sore throat. On admission she had raised inflammatory markers and a subsequent blood culture demonstrated a fusobacterium necrophorum and arcanobacterium haemolyticum bacteraemia. Further investigations established an internal jugular vein thrombosis, confirming the diagnosis of Lemierre's syndrome. This case highlights the importance of further investigation when a sore throat fails to improve, and to remember this often-forgotten syndrome...
2017: Acute Medicine
https://www.readbyqxmd.com/read/29070428/lemierre-syndrome-after-tonsillectomy
#18
Daniel R Quast, Tanja A Lotz, Thomas G K Breuer
No abstract text is available yet for this article.
October 6, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29054895/lemierre-s-syndrome-variant-of-the-gut
#19
Thomas E Mellor, Natalie Mitchell, Jessica Logan
Infectious suppurative thrombophlebitis of the portal venous system, referred to as pylephlebitis, is a rare complication of intra-abdominal inflammatory processes. Advances in diagnostics and antibiotics have improved survival, but mortality remains remarkably high even in the most recent literature. The majority of patients have concomitant bacteraemia on presentation most commonly with typical gastrointestinal (GI) organisms. On rare occasion, patients have culture positive Fusobacterium, which has recently been associated with occult GI and genitourinary malignancies...
October 20, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29046755/some-neck-swellings-are-serious-a-case-of-lemierre-s-syndrome
#20
Ali Raza Ghani, Mohsin Hamid, Ahsan Raza, Rizwan Naseer, Joseph Crocetti
Lemierre's syndrome also termed post-anginal septicemia, is a disease characterized by internal jugular septic thrombophlebitis leading to Fusobacterium septicemia with multiple metastatic foci following an oropharyngeal infection. Diagnosis and management is challenging and can result in fatal consequences due to potential multisystem involvement and multiple complications. We describe here a case of Lemierre's syndrome with multifocal pneumonia, acute renal failure and protracted course of illness over forty days with successful recovery...
October 2017: Journal of Community Hospital Internal Medicine Perspectives
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