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https://www.readbyqxmd.com/read/27907850/automated-annotation-and-quantitative-description-of-ultrasound-videos-of-the-fetal-heart
#1
Christopher P Bridge, Christos Ioannou, J Alison Noble
Interpretation of ultrasound videos of the fetal heart is crucial for the antenatal diagnosis of congenital heart disease (CHD). We believe that automated image analysis techniques could make an important contribution towards improving CHD detection rates. However, to our knowledge, no previous work has been done in this area. With this goal in mind, this paper presents a framework for tracking the key variables that describe the content of each frame of freehand 2D ultrasound scanning videos of the healthy fetal heart...
November 19, 2016: Medical Image Analysis
https://www.readbyqxmd.com/read/27906782/predicting-heart-dose-in-breast-cancer-patients-who-received-3d-conformal-radiation-therapy
#2
Daniel Wollschläger, Heiko Karle, Marcus Stockinger, Detlef Bartkowiak, Sandra Bührdel, Hiltrud Merzenich, Thomas Wiegel, Heinz Schmidberger, Maria Blettner
Cardiac late effects are a major health concern for long-term survivors after radiotherapy for breast cancer. Large cohort studies to better understand the exact dose-response relationship require individual estimates of radiation dose to the heart. To predict individual cardiac dose from information that is typically available for all members of a retrospective epidemiological cohort study, 774 female breast cancer patients treated with megavoltage tangential field radiotherapy in 1998-2008 were examined. All dose distributions were calculated using Eclipse with the anisotropic analytical algorithm (AAA) for photon fields and the electron Monte Carlo algorithm for electron boost fields...
January 2017: Health Physics
https://www.readbyqxmd.com/read/27899937/predictive-value-of-syntax-score-ii-for-clinical-outcomes-in-octogenarian-undergoing-percutaneous-coronary-intervention
#3
Evan Kurniawan, Feng-Hua Ding, Qi Zhang, Zhen-Kun Yang, Jian Hu, Wei-Feng Shen, Rui-Yan Zhang
OBJECTIVE: To evaluate the predictive value of SYNTAX Score II (SS-II) for percutaneous coronary intervention (PCI) in octogenarian (≥ 80 years old) undergoing PCI. METHODS & RESULTS: Data from three consecutive years of octogenarian undergoing PCI from Ruijin Hospital (Shanghai, China) was retrospectively collected (n = 308). Follow up clinical data at one year including all cause mortality, cardiac mortality and main adverse cardiovascular and cerebrovascular events (MACCE) were collected...
September 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27891328/abnormal-course-of-right-coronary-artery-together-with-variant-left-coronary-artery-and-partial-atresia-of-cicumflex-artery
#4
Rajani Singh
Heart is supplied by right and left coronary arteries. Therefore, the knowledge of normal and variant anatomy of both these arteries and their configurations is indispensable for proper understanding of diagnosis and treatment of dreaded cardiac diseases. During routine cadaveric dissection, a heart of an adult female with anomalous course of Right Coronary Artery (RCA), new variant of trifurcated Left Coronary Artery (LCA) and partial atresia of circumflex (CX) artery was detected. Trifurcation of LCA into anterior interventricular, CX and a ramus intermedius without giving accessory branches has been reported...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27888758/left-atrium-and-pulmonary-vein-imaging-using-sub-millisiviert-cardiac-computed-tomography-impact-on-radiofrequency-catheter-ablation-cumulative-radiation-exposure-and-outcome-in-atrial-fibrillation-patients
#5
Gianluca Pontone, Daniele Andreini, Maria Petulla, Andrea Annoni, Andrea I Guaricci, Ester Innocenti, Eleonora Russo, Marco Guglielmo, Saima Mushtaq, Andrea Baggiano, Virginia Beltrama, Laura Fusini, Chiara Segurini, Edoardo Conte, Alberto Formenti, Gaetano Fassini, Stefania Riva, Claudio Tondo, Piergiuseppe Agostoni, Antonio L Bartorelli, Mauro Pepi
BACKGROUND: The outcome of radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) has improved thanks to left atrium (LA) anatomy reconstruction by cardiac computed tomography (CCT). A new model-based iterative reconstruction algorithm (MBIR) provides image noise reduction achieving effective radiation dose (ED) close to chest X-ray exposure. Aim of this study was comparing RFCA procedural characteristics, AF recurrence and radiation exposure between patients in whom RFCA was guided by CCT image integration with MBIR versus a CCT standard protocol...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27888398/the-value-of-the-electrocardiogram-for-evaluating-prognosis-in-patients-with-idiopathic-pulmonary-arterial-hypertension
#6
Xiao-Ling Cheng, Jian-Guo He, Zhi-Hong Liu, Qing Gu, Xin-Hai Ni, Zhi-Hui Zhao, Qin Luo, Chang-Ming Xiong
BACKGROUND: Association between electrocardiography (ECG) features and right ventricular anatomy and physiology has been established. This study is aimed to identify the value of 12-lead ECG in evaluating prognosis of patients with idiopathic pulmonary arterial hypertension (IPAH). METHOD: 194 patients with newly diagnosed IPAH were included in this study. Correlations between electrocardiography variables and hemodynamics were assessed. Univariate and multivariable cox regression analysis were performed to identify ECG variables for predicting all-cause mortality in IPAH...
November 25, 2016: Lung
https://www.readbyqxmd.com/read/27886934/coronary-sinus-lead-positioning
#7
REVIEW
Attila Roka, Rasmus Borgquist, Jagmeet Singh
Although cardiac resynchronization therapy improves morbidity and mortality in patients with cardiomyopathy, heart failure, and electrical dyssynchrony, the rate of nonresponders using standard indications and implant techniques is still high. Optimal coronary sinus lead positioning is important to increase the chance of successful resynchronization. Patient factors such as cause of heart failure, type of dyssynchrony, scar burden, coronary sinus anatomy, and phrenic nerve capture may affect the efficacy of the therapy...
January 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/27885749/biophysical-modeling-to-determine-the-optimization-of-left-ventricular-pacing-site-and-av-vv-delays-in-the-acute-and-chronic-phase-of-cardiac-resynchronization-therapy
#8
Angela Lee, Andrew Crozier, Eoin R Hyde, Pablo Lamata, Michael Truong, Manav Sohal, Thomas Jackson, Jonathan M Behar, Simon Claridge, Anoop Shetty, Eva Sammut, Gernot Plank, Christopher Aldo Rinaldi, Steven Niederer
BACKGROUND: Cardiac anatomy and function adapt in response to chronic cardiac resynchronization therapy (CRT). The effects of these changes on the optimal left ventricle (LV) lead location and timing delay settings have yet to be fully explored. OBJECTIVE: To predict the effects of chronic CRT on the optimal LV lead location and device timing settings over time. METHODS: Biophysical computational cardiac models were generated for 3 patients, immediately post-implant (ACUTE) and after at least 6 months of CRT (CHRONIC)...
November 25, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27882341/using-mri-to-predict-future-adverse-cardiac-remodelling-in-a-male-mouse-model-of-myocardial-infarction
#9
Rachael E Redgrave, Simon Tual-Chalot, Benjamin J Davison, Elizabeth Greally, Mauro Santibanez-Koref, Jurgen E Schneider, Andrew M Blamire, Helen M Arthur
BACKGROUND: Mice are frequently used in research to examine outcomes of myocardial infarction (MI) and to investigate therapeutic interventions at an early pre-clinical stage. The MI model is generated by surgically occluding a major coronary artery, but natural variation in murine coronary anatomy can generate variable outcomes that will inevitably affect the accuracy of such investigations. The aim of this study was to use MRI to derive the most sensitive early variable that could be used to predict subsequent adverse cardiac remodelling in a male mouse model of MI...
June 2016: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/27881562/total-anomalous-pulmonary-venous-connection-the-current-management-strategies-in-a-pediatric-cohort-of-768-patients
#10
Guocheng Shi, Zhongqun Zhu, Jimei Chen, Yanqiu Ou, Haifa Hong, Zhiqiang Nie, Haibo Zhang, Xiaoqing Liu, Jinghao Zheng, Qi Sun, Jinfen Liu, Huiwen Chen, Jian Zhuang
BACKGROUND: -Total anomalous pulmonary venous connection (TAPVC) is a rare form of congenital heart disease. This study describes current surgical treatment strategies and experiences for a cohort of patients from two congenital cardiac centers in Shanghai and Guangdong, China. METHODS: -This retrospective study included 768 patients operated on between 2005 and 2014. While most patients (n=690) underwent conventional repair, a sutureless technique was employed in 10% (n=78) of cases...
November 15, 2016: Circulation
https://www.readbyqxmd.com/read/27878634/relationship-between-habitual-exercise-and-performance-on-cardiopulmonary-exercise-testing-differs-between-children-with-single-and-biventricular-circulations
#11
Michael L O'Byrne, Sanyukta Desai, Megan Lane, Michael McBride, Stephen Paridon, Elizabeth Goldmuntz
Increasing habitual exercise has been associated with improved cardiopulmonary exercise testing (CPET) performance, specifically maximal oxygen consumption in children with operatively corrected congenital heart disease. This has not been studied in children following Fontan palliation, a population in whom CPET performance is dramatically diminished. A single-center cross-sectional study with prospective and retrospective data collection was performed that assessed habitual exercise preceding a clinically indicated CPET in children and adolescents with Fontan palliation, transposition of the great arteries following arterial switch operation (TGA), and normal cardiac anatomy without prior operation...
November 23, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27875591/reentry-and-ectopic-pacemakers-emerge-in-a-three-dimensional-model-for-a-slab-of-cardiac-tissue-with-diffuse-microfibrosis-near-the-percolation-threshold
#12
Sergio Alonso, Rodrigo Weber Dos Santos, Markus Bär
Arrhythmias in cardiac tissue are generally associated with irregular electrical wave propagation in the heart. Cardiac tissue is formed by a discrete cell network, which is often heterogeneous. Recently, it was shown in simulations of two-dimensional (2D) discrete models of cardiac tissue that a wave crossing a fibrotic, heterogeneous region may produce reentry and transient or persistent ectopic activity provided the fraction of conducting connections is just above the percolation threshold. Here, we investigate the occurrence of these phenomena in three-dimensions by simulations of a discrete model representing a thin slab of cardiac tissue...
2016: PloS One
https://www.readbyqxmd.com/read/27873373/cardiac-output-and-blood-flow-redistribution-in-the-fetus-with-d-loop-transposition-of-the-great-arteries-and-intact-ventricular-septum-insights-into-the-pathophysiology
#13
Max E Godfrey, Kevin G Friedman, Monika Drogosz, Abraham M Rudolph, Wayne Tworetzky
OBJECTIVES: Although the postnatal physiology of D-loop transposition of the great arteries with intact ventricular septum (DTGA-IVS) is well established, little is known about fetal DTGA-IVS. In the normal fetus, the pulmonary valve (PV) is larger than the aortic valve (AoV), there is exclusive right to left flow at the foramen ovale (FO) and ductus arteriosus (DA), and the left ventricle (LV) ejects 40% of combined ventricular output (CVO) through the aorta, primarily to the brain. In DTGA-IVS, the LV ejects O2 -rich blood to the pulmonary artery, theoretically leading to pulmonary vasodilation, increased branch pulmonary arterial flow and reduced DA flow...
November 22, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27872994/outcomes-of-tracheostomy-in-children-requiring-surgery-for-congenital-heart-disease
#14
Laura A Ortmann, Winston M Manimtim, Charisse I Lachica
Outcomes after discharge in children requiring tracheostomy after cardiac surgery have not been fully described. A retrospective, single-center study was performed on all children <18 years of age requiring both tracheostomy and surgery for congenital heart disease from January 2002 to May 2015. Forty-six tracheostomies were placed after surgery and four before. Single-ventricle anatomy was present in 12 (33%) patients. Incidence of tracheostomy after heart surgery increased from 0.8% the first half of the study period to 2% the second half...
November 21, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27869889/-anmco-sicp-sigo-consensus-document-pregnancy-and-congenital-heart-disease
#15
Innocenzo Bianca, Giovanna Geraci, Michele Massimo Gulizia, Gabriele Egidy-Assenza, Chiara Barone, Marcello Campisi, Annalisa Alaimo, Rachele Adorisio, Francesca Comoglio, Silvia Favilli, Gabriella Agnoletti, Maria Gabriella Carmina, Massimo Chessa, Berardo Sarubbi, Maurizio Mongiovì, Maria Giovanna Russo, Sebastiano Bianca, Giuseppe Canzone, Marco Bonvicini, Elsa Viora, Marco Poli
The success of cardiac surgery over the past 50 years has increased numbers and median age of survivors with congenital heart disease (CHD). Adults now represent two-thirds of patients with CHD; in the United States alone the number is estimated to exceed 1 million.In this population many affected women reach reproductive age and wish to have children. While in many CHD patients pregnancy can be accomplished successfully, some special situations with complex anatomy, iatrogenic or residual pathology are associated with an increased risk of severe maternal and fetal complications...
September 2016: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/27869052/altering-management-decisions-with-gained-anatomical-insight-from-a-3d-printed-model-of-a-complex-ventricular-septal-defect
#16
Puneet Bhatla, Ralph S Mosca, Justin T Tretter
Rapid prototyping is quickly gaining utility in various complex forms of CHD. In properly selected cases, these printed models provide detailed anatomical understanding that help guide potential surgical and cardiac catheterisation interventions. We present a case of a tunnel-like ventricular septal defect referred for surgical repair, where the decision to obtain a three-dimensional printed model helped in better understanding of the anatomy, leading to delaying, and hopefully avoiding altogether, surgical repair...
November 21, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27867587/acute-chest-pain-in-a-triathlete-rupture-of-the-noncoronary-sinus-of-valsalva-into-the-right-ventricle
#17
Ernan Zhu, Ralf Westenfeld, Mareike Gastl, Florian Bönner, Alexander Assmann, Amir M Nia, Malte Kelm, Christian Jung
Sinus of Valsalva (SoV) aneurysm is a rare cardiac disease which can be congenital or acquired. A ruptured SoV aneurysm presents a clinical emergency and can lead to progressively deteriorating heart failure. Therefore, appropriate treatment requires prompt and accurate diagnosis. Most ruptured or nonruptured SoV aneurysms are diagnosed by the means of echocardiography. However, cardiovascular magnetic resonance (CMR) can provide information on precise anatomy and mechanisms due to its excellent soft tissue contrast and high resolution, and thereby allows for optimized preoperative planning of the repair strategy...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27866675/hemodynamics-of-patient-specific-aorta-pulmonary-shunt-configurations
#18
Senol Piskin, H Firat Altin, Okan Yildiz, Ihsan Bakir, Kerem Pekkan
Optimal hemodynamics in aorta-pulmonary shunt reconstruction is essential for improved post-operative recovery of the newborn congenital heart disease patient. However, prior to in vivo execution, the prediction of post-operative hemodynamics is extremely challenging due to the interplay of multiple confounding physiological factors. It is hypothesized that the post-operative performance of the surgical shunt can be predicted through computational blood flow simulations that consider patient size, shunt configuration, cardiac output and the complex three-dimensional disease anatomy...
November 11, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27866077/the-concept-of-double-inlet-double-outlet-right-ventricle-a-distinct-congenital-heart-disease
#19
Veronica Spadotto, Carla Frescura, Siew Yen Ho, Gaetano Thiene
The aim of this study was to estimate the incidence and to analyze the anatomy of double inlet-double outlet right ventricle complex and its associated cardiac anomalies in our autopsy series. Among the 1640 hearts with congenital heart disease of our Anatomical Collection, we reviewed the specimens with double inlet-double outlet right ventricle, according to the sequential-segmental analysis, identifying associated cardiac anomalies and examining lung histology to assess the presence of pulmonary vascular disease...
September 25, 2016: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/27863351/abnormal-heart-rate-response-during-cardiopulmonary-exercise-testing-identifies-cardiac-dysfunction-in-symptomatic-patients-with-non-obstructive-coronary-artery-disease
#20
Sundeep Chaudhry, Naresh Kumar, Hushyar Behbahani, Akshay Bagai, Binoy K Singh, Nick Menasco, Gregory D Lewis, Laurence Sperling, Jonathan Myers
BACKGROUND: Symptomatic non-obstructive coronary artery disease is a growing clinical dilemma for which contemporary testing is proving to be of limited clinical utility. New methods are needed to identify cardiac dysfunction. METHODS AND RESULTS: This is a prospective observational cohort study conducted from December 2013 to August 2015 in two outpatient cardiology clinics (symptomatic cohort) and 24 outpatient practices throughout the US (healthy cohort) with centralized methodology and monitoring to compare heart-rate responses during cardiopulmonary exercise testing (CPET)...
November 14, 2016: International Journal of Cardiology
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