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https://www.readbyqxmd.com/read/28103518/adsorption-of-quinolone-tetracycline-and-penicillin-antibiotics-from-aqueous-solution-using-activated-carbons-review
#1
REVIEW
Muthanna J Ahmed
Antibiotics, an important type of pharmaceutical pollutant, have attracted many researchers to the study of their removal from aqueous solutions. Activated carbon (AC) has been widely used as highly effective adsorbent for antibiotics because of its large specific surface area, high porosity, and favorable pore size distribution. In this article, the adsorption performance of AC towards three major types of antibiotics such as tetracyclines, quinolones, and penicillins were reviewed. According to collected data, maximum adsorption capacities of 1340...
January 16, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28103262/serotype-distribution-and-antimicrobial-sensitivity-profile-of-streptococcus-pneumoniae-carried-in-healthy-toddlers-before-pcv13-introduction-in-niamey-niger
#2
Sani Ousmane, Bouli A Diallo, Rasmata Ouedraogo, Abdel-Kader A Sanda, Amadou M Soussou, Jean-Marc Collard
BACKGROUND: To mitigate the burden of pneumococcal infections in Niger, a 13-valent pneumococcal vaccine, PCV13, was introduced for routine child vaccination in July 2014. In order to provide pre-vaccine baseline data and allow appreciation of changes on carriage due to vaccination, we analyzed retrospectively pneumococcal isolates obtained from healthy, 0 to 2 year old children prior to the vaccine introduction. METHODS: From June 5, 2007, to May 26, 2008, 1200 nasopharyngeal swabs were collected from healthy 0 to 2 year old children and analyzed by standard microbiological methods...
2017: PloS One
https://www.readbyqxmd.com/read/28103259/characterization-and-genetic-variation-of-vibrio-cholerae-isolated-from-clinical-and-environmental-sources-in-thailand
#3
Achiraya Siriphap, Pimlapas Leekitcharoenphon, Rolf S Kaas, Chonchanok Theethakaew, Frank M Aarestrup, Orasa Sutheinkul, Rene S Hendriksen
Cholera is still an important public health problem in several countries, including Thailand. In this study, a collection of clinical and environmental V. cholerae serogroup O1, O139, and non-O1/non-O139 strains originating from Thailand (1983 to 2013) was characterized to determine phenotypic and genotypic traits and to investigate the genetic relatedness. Using a combination of conventional methods and whole genome sequencing (WGS), 78 V. cholerae strains were identified. WGS was used to determine the serogroup, biotype, virulence, mobile genetic elements, and antimicrobial resistance genes using online bioinformatics tools...
2017: PloS One
https://www.readbyqxmd.com/read/28100194/interspecies-transfer-of-vancomycin-erythromycin-and-tetracycline-resistance-among-enterococcus-species-recovered-from-agrarian-sources
#4
M Conwell, V Daniels, P J Naughton, J S G Dooley
BACKGROUND: Enterococci are now well recognised for their ability to transfer antibiotic resistance and for their association with nosocomial infections, but less is known regarding their relevance in the wider environment. Enterococcus faecalis and Enterococcus faecium were isolated from a range of agrarian associated sources (low-flow water, septic tank, poultry litter, high flow water, slurry/soil) and were assessed for latent ability to transfer antimicrobial resistance. RESULTS: The isolates were tested for phenotypic clumping in the presence of cell-free supernatant from other isolates...
January 18, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28094507/conjugated-polyelectrolyte-based-sensitive-detection-and-removal-of-antibiotics-tetracycline-from-water
#5
Akhtar Hussain Malik, Parameswar Krishnan Iyer
A new conjugated polyelectrolyte poly[5,5'-(((2-phenyl-9H-fluorene-9,9-diyl)bis(hexane-6,1-diyl))bis(oxy))diisophthalate] sodium (PFPT) was synthesized via Palladium catalysed Suzuki cross coupling polymerization method and successfully applied for the rapid, real time and highly sensitive detection of antibiotics tetracycline (Tc) in 100% aqueous media via photo-induced electron transfer with detection limit in ppb level. Remarkably, PFPT could also be applied for the trace analysis of Tc in serum samples having recoveries well in the range 92-97% with relative standard deviations (RSD) of 1...
January 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28094219/3-4-dihydropyrimidinone-coumarin-analogues-as-a-new-class-of-selective-agent-against-s-aureus-synthesis-biological-evaluation-and-molecular-modelling-study
#6
Nirmala S Naik, Lokesh A Shastri, Shrinivas D Joshi, Sheshagiri R Dixit, Bahubali M Chougala, S Samundeeswari, Megharaj Holiyachi, Farzanabi Shaikh, Jyoti Madar, Rashmi Kulkarni, Vinay Sunagar
Bacterial infections are increasingly difficult to combat as bacteria evolve resistance to antibiotic drugs and have severely compromised the arsenal of antibiotic drugs. On the other hand matrix metalloproteinases (MMPs) play a fundamental role in inflammation and extracellular matrix degradation in physiological and pathological conditions. In search of potent antibiotic, taking coumarin and dihydropyrimidinone as lead compound, a green, eco-friendly and efficient protocol has been developed and synthesized the dihydropyrimidin-2(1H)-one/thione derivatives of coumarin 3/4 from substituted 4-formylcoumarins 2 and ethylacetoacetate using urea/thiourea in the presence of catalytic amount of ceric ammonium nitrate is reported...
January 5, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28090784/effect-of-resveratrol-and-tetracycline-on-the-subacute-paraquat-toxicity-in-mice
#7
R M Satpute, P P Pawar, S Puttewar, S D Sawale, P D Ambhore
Paraquat (PQ) is a nonselective bipyridyl herbicide widely used in agriculture to control weeds, but its accidental, occupational, or intentional exposure in humans is known to cause pneumo- and neurotoxicity which may proves fatal. Oxidative stress is reported as an underlined mechanism of PQ-induced toxicity in alveolar cells, neurons, and astroglia. PQ generates superoxides both through electron transport reaction (ETC) with nicotinamide adenine dinucleotide-dependent oxidoreductase and by the redox cycling via reaction with molecular oxygen...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28088753/mitochondrial-redox-plays-a-critical-role-in-the-paradoxical-effects-of-napdh-oxidase-derived-ros-on-coronary-endothelium
#8
Ehtesham Shafique, Anali Torina, Karla Reichert, Bonnie Colantuono, Nasifa Nur, Khawaja Zeeshan, Vani Ravichandran, Yuhong Liu, Jun Feng, Khawaja Zeeshan, Laura E Benjamin, Kaikobad Irani, Elizabeth O Harrington, Frank W Sellke, Md Ruhul Abid
AIMS: There are conflicting reports on the role of reactive oxygen species (ROS) i.e. beneficial vs. harmful, in vascular endothelium. Here, we aim to examine whether duration of exposure to ROS and/or subcellular ROS levels are responsible for the apparently paradoxical effects of oxidants on endothelium. METHODS AND RESULTS: We have recently generated binary (Tet-ON/OFF) conditional transgenic mice (Tet-Nox2:VE-Cad-tTA) that can induce 1.8 ± 0.42-fold increase in NADPH oxidase (NOX)-derived ROS specifically in vascular endothelium upon withdrawal of tetracycline from the drinking water...
January 14, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28088749/dual-channel-probe-of-carbon-dots-cooperating-with-gold-nanoclusters-employed-for-assaying-multiple-targets
#9
Kuncheng Yang, Shanshan Wang, Yingyi Wang, Hong Miao, Xiaoming Yang
Herein, carbon dots (CD@Papain) from papain have been originally synthesized in aqueous solution along with a quantum yield of 6.2%, and showed cyan fluorescence at 435nm. Meanwhile, papain-templated Au nanoclusters (AuNCs@Papain) were prepared with the same precursor. On the basis of the two types of nanomaterials, CD@Papain and AuNCs@Papain have been designed to assemble as one nanosensor (termed as CD-AuNCs@Papain) through a typical cross-linking reaction. Significantly, it not only emitted the dual-emission fluorescent signals with the same excitation, but also can assay multiple targets through exhibiting cyan, yellow, and red emission respectively...
January 7, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28088717/removal-of-antibiotic-resistance-genes-from-wastewater-treatment-plant-effluent-by-coagulation
#10
Na Li, Guo-Ping Sheng, Yong-Ze Lu, Raymond J Zeng, Han-Qing Yu
Antibiotic resistance genes (ARGs), as emerging environmental contaminants, have become a threat to human health. Recent studies have demonstrated that the effluent from wastewater treatment plants is a significant point source of ARGs released into the environment. In this study, we investigated the effectiveness of coagulation technology in the removal of ARGs from treated wastewater. Specifically, we measured the removal of five ARGs (two sulfonamide resistance genes, sulI and sulII, and three tetracycline resistance genes, tetO, tetW and tetQ) and the class 1 integron intI1 gene via the application of two coagulants: FeCl3 and polyferric chloride (PFC)...
January 4, 2017: Water Research
https://www.readbyqxmd.com/read/28088530/distribution-of-antibiotic-resistance-in-the-effluents-of-ten-municipal-wastewater-treatment-plants-in-china-and-the-effect-of-treatment-processes
#11
Weiwei Ben, Jian Wang, Rukun Cao, Min Yang, Yu Zhang, Zhimin Qiang
Municipal wastewater treatment plant (WWTP) effluents represent an important contamination source of antibiotic resistance, threatening the ecological safety of receiving environments. In this study, the release of antibiotic resistance to sulfonamides and tetracyclines in the effluents of ten WWTPs in China was investigated. Results indicate that the concentrations of antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) ranged from 1.1 × 10(1) to 8.9 × 10(3) CFU mL(-1) and 3.6 × 10(1) (tetW) to 5...
January 6, 2017: Chemosphere
https://www.readbyqxmd.com/read/28088472/cholesterol-and-ergosterol-affect-the-activity-of-staphylococcus-aureus-antibiotic-efflux-pumps
#12
S R Tintino, C D M Oliveira-Tintino, F F Campina, M S Costa, R P Cruz, R L S Pereira, J C Andrade, E O Sousa, J P Siqueira-Junior, H D M Coutinho, T C Leal-Balbino, V Q Balbino
The aim of this study is to evaluate the effect of ergosterol on steroids and cholesterol efflux pumps in multidrug resistant strains of S. aureus. Were used RN4220 harboring plasmid pUL5054, which carries the gene encoding the MsrA macrolide efflux protein; and IS-58, which possesses the TetK tetracycline efflux protein; 1199B resists hydrophilic fluoroquinolones via a NorA-mediated mechanism and wild strain 1199B. The Minimal Inhibitory Concentration (MIC) was determined and the evaluation of possible inhibition of efflux pumps by reduction of MIC...
January 11, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28087584/emergence-of-klebsiella-variicola-positive-for-ndm-9-a-variant-of-new-delhi-metallo-%C3%AE-lactamase-in-an-urban-river-in-south-korea
#13
Doris Y W Di, Jeonghwan Jang, Tatsuya Unno, Hor-Gil Hur
OBJECTIVES: To examine the presence of pathogenic bacteria carrying New Delhi metallo-β-lactamase in the environment and to characterize the genome structures of these strains. METHODS: Phenotypic screening of antimicrobial susceptibility and WGS were conducted on three Klebsiella variicola strains possessing NDM-9 isolated from an urban river. RESULTS: Three carbapenem-resistant K. variicola isolated from Gwangju tributary were found to possess blaNDM-9 genes...
January 12, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28087306/molecular-epidemiological-analysis-of-human-and-chicken-derived-isolates-of-campylobacter-jejuni-in-japan-using-next-generation-sequencing
#14
Takayuki Ohishi, Kotaro Aoki, Yoshikazu Ishii, Masaru Usui, Yutaka Tamura, Michiko Kawanishi, Ohnishi Kenji, Kazuhiro Tateda
In this research, we analyzed the main sequence types (ST) and ST complexes of human- and chicken-derived isolates of Campylobacter jejuni in Japan by using multilocus sequence typing (MLST). We also analyzed lipooligosaccharide biosynthesis locus classes (LOS locus classes) and the numbers of isolates carrying genes coding resistance factors against various antibiotics, and observed their relationships. ST-21 complex was the main ST complex in isolates from humans (n = 38) and chickens (n = 25). None of the isolates showed resistance to imipenem, chloramphenicol, or erythromycin...
January 10, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28081347/virulence-factors-biofilm-forming-ability-and-antimicrobial-resistance-of-urinary-escherichia-coli-strains-isolated-from-hospitalized-patients
#15
Barbara Kot, Jolanta Wicha, Agata Grużewska, Małgorzata Piechota, Katarzyna Wolska, Maria Obrębska
BACKGROUND/AIM: Escherichia coli is the most frequent cause of urinary tract infections. We investigated the possible associations between the origin of strains, antimicrobial resistance, the presence of urovirulence factors, and biofilm-forming ability. MATERIALS AND METHODS: Antibiotic susceptibility of E. coli strains was tested by disk diffusion method. Hemagglutination assays were performed for phenotypic characterization of the cell surface. Multiplex PCR was used for detection of virulence genes and for determination of phylogenetic relationships...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28081148/characterization-of-multi-drug-resistant-enterococcus-faecalis-isolated-from-cephalic-recording-chambers-in-research-macaques-macaca-spp
#16
Stephanie E Woods, Mia T Lieberman, Francois Lebreton, Elise Trowel, César de la Fuente-Núñez, Joanne Dzink-Fox, Michael S Gilmore, James G Fox
Nonhuman primates are commonly used for cognitive neuroscience research and often surgically implanted with cephalic recording chambers for electrophysiological recording. Aerobic bacterial cultures from 25 macaques identified 72 bacterial isolates, including 15 Enterococcus faecalis isolates. The E. faecalis isolates displayed multi-drug resistant phenotypes, with resistance to ciprofloxacin, enrofloxacin, trimethoprim-sulfamethoxazole, tetracycline, chloramphenicol, bacitracin, and erythromycin, as well as high-level aminoglycoside resistance...
2017: PloS One
https://www.readbyqxmd.com/read/28078872/molecular-characterization-and-antibiotic-resistance-of-salmonella-serovars-isolated-in-the-apulia-region-of-italy
#17
R Mirgaldi, A Ballini, A M Dionisi, I Luzzi, G Dipalma, F Inchingolo, D De Vito
During the period January 2013-December 2015, 175 cases of human salmonellosis were reported in the Apulia Region of Italy. The aim of this study was to characterize salmonella strains from the standpoints of serovars prevalence, antimicrobial resistance and clonal origin. The serological typing was performed by agglutination against antisera followed by a multiplex polymerase chain reaction (m-PCR). The obtained results were analyzed following the Kauffmann-White scheme. Susceptibility to antimicrobial agents was tested using the disk diffusion method on Muller-Hinton agar plates...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28077432/determination-of-tetracyclines-in-bovine-milk-using-laccaic-acid-loaded-magnetite-nanocomposite-for-magnetic-solid-phase-extraction
#18
Youwei Yu, Zhefeng Fan
An efficient magnetic sorbent of laccaic acid-loaded magnetite nanocomposite was successfully synthesized for extraction and preconcentration of tetracyclines (TCs) from bovine milk sample. The synthesized nanocomposite was characterized by scanning electron microscopy and Fourier transform-infrared spectroscopy. Determination of the extracted TCs was performed by high performance liquid chromatography. Parameters affecting the efficiency of magnetic solid-phase extraction were studied and optimized. The best adsorption conditions were 80 mg of sorbent, 50 mL of sample volume, pH 7, 45°C and 20 min; the elution conditions were 0...
January 10, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28075235/staphylococcus-pseudintermedius-human-infection-cases-in-spain-dog-to-human-transmission
#19
Carmen Lozano, Antonio Rezusta, Isabel Ferrer, Vanesa Pérez-Laguna, Myriam Zarazaga, Laura Ruiz-Ripa, María José Revillo, Carmen Torres
Staphylococcus pseudintermedius is an opportunistic pathogen that has been identified as infectious agent or colonizer mainly in dogs. S. pseudintermedius has been also detected in humans and more specifically in people in contact with dogs. In this study, the possible S. pseudintermedius pet-to-human transmission was analyzed in four clinical human cases. Two patients were dog owners and S. pseudintermedius was also detected as colonizer in these healthy animals. S. pseudintermedius isolates from patients and dogs of the same household showed identical pulsed-field gel electrophoresis patterns, sequence types (STs), and antimicrobial resistance phenotypes and genotypes, and were methicillin susceptible...
January 11, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28074125/shiga-vero-toxin-producing-escherichia-coli-isolated-from-the-hospital-foods-virulence-factors-o-serogroups-and-antimicrobial-resistance-properties
#20
Reza Ranjbar, Mojtaba Masoudimanesh, Farhad Safarpoor Dehkordi, Nematollah Jonaidi-Jafari, Ebrahim Rahimi
BACKGROUND: According to the presence of the weak, diabetic and immunosuppressive patients in hospitals, hospital foods should have a high quality and safety. Cooking a lot of foods higher than daily requirement, storage of cooked foods in an inappropriate condition and presence of nurses and servants in distribution of food to patients are the main reasons caused contamination of hospital foods. Shiga toxigenic Escherichia coli is one of the common cause of food poisoning in hospitals...
2017: Antimicrobial Resistance and Infection Control
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