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Mucosal prolapse

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https://www.readbyqxmd.com/read/27898453/resolution-of-rectal-prolapse-by-vaginal-reconstruction
#1
Hemikaa Devakumar, Neeraja Chandrasekaran, Alexandriah Alas, Laura Martin, G Willy Davila, Eric Hurtado
BACKGROUND: Rectal prolapse is a disorder of the pelvic floor in which the layers of the rectal mucosa protrude outward through the anus. Surgical repair is the mainstay of treatment. Options include intra-abdominal procedures such as rectopexy and perineal procedures such as the Delorme and Altemeier perineal rectosigmoidectomy. Rectal and vaginal prolapse can often coexist. However, to our knowledge, there are no reported cases of rectal prolapse resolved by the repair of a compressive enterocele abutting the anterior rectal wall through a vaginal approach alone...
November 28, 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27894384/-reconstruction-of-anal-stenosis-induced-by-scar-contracture-after-repair-of-defect-in-perineal-region-with-paraumbilical-flap-using-random-pattern-flap
#2
Q Liu, X B You, Z Cai, K Y Tang, H Zhang
Objective: To investigate the method and timing of reconstruction of anal stenosis induced by scar contracture after repair of defect in perineal region with paraumbilical flap using random pattern flap. Methods: Ten patients who suffered anal stenosis induced by scar contracture after the first phase repair of defect of perineal region with paraumbilical flap were hospitalized from July 2009 to September 2015. Eight patients were with central type scar contracture of perineal region after healing of burn wound, and two patients were with lesion of perineal region which had been excised...
November 20, 2016: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/27807575/intestinal-perforation-following-ileoscopy-through-a-prolapsed-stoma-in-an-pediatric-intestinal-transplant-recipient-with-an-unrecognized-parastomal-hernia
#3
Pavni Mehrotra, Joanna Yeh, Theodore R Hall, Vatche G Agopian, Douglas G Farmer, Elizabeth A Marcus, Robert S Venick, Laura J Wozniak
Ileoscopy with mucosal biopsy is fundamental in the management and surveillance of inflammatory bowel disease patients and intestinal transplant recipients. There is a paucity of data describing the risks of ileoscopy in the presence of a prolapsed stoma. Parastomal hernias are frequently associated with prolapsed stomas. We report the first case of perforation during ileoscopy in the setting of a prolapsed stoma and unrecognized parastomal hernia. Recognition of parastomal hernia associated with stoma prolapse is of paramount importance in patients undergoing ileoscopy as it may increase the risk of perforation...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27801539/does-a-more-extensive-mucosal-excision-prevent-haemorrhoidal-recurrence-after-stapled-haemorrhoidopexy-long-term-outcome-of-a-randomised-controlled-trial
#4
Donato F Altomare, Giuseppe Pecorella, Guido Tegon, Fabrizio Aquilino, Damiano Pennisi, Michele De Fazio
AIM: The study aimed in a multicentric randomised controlled trial to define the role of a more extensive mucosal resection on recurrence of mucosal prolapse in patients with stage III haemorrhoids undergoing stapled haemorrhoidopexy . METHOD: 135 patients were randomised to treatment with PPH01/03 or an EEA stapler. They were reviewed after a minimum follow-up of four years to determine the rate of recurrent mucosal prolapse, and general condition (Wellness evaluation score)...
November 1, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27683801/cell-specific-activation-of-the-nrf2-antioxidant-pathway-increases-mucosal-inflammation-in-acute-but-not-in-chronic-colitis
#5
Alexandra Gerstgrasser, Hassan Melhem, Irina Leonardi, Kirstin Atrott, Matthias Schäfer, Sabine Werner, Gerhard Rogler, Isabelle Frey-Wagner
BACKGROUND AND AIMS: The transcription factor Nrf2 is a major modulator of the cellular antioxidant response. Oxidative burst of infiltrating macrophages leads to a massive production of reactive oxygen species in inflamed tissue of inflammatory bowel disease patients. This oxidative burst contributes to tissue destruction and epithelial permeability, but it is also an essential part of the antibacterial defense. We therefore investigated the impact of the Nrf2 orchestrated antioxidant response in both acute and chronic intestinal inflammation...
September 28, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27641548/laparoscopic-ventral-rectopexy-in-male-patients-with-external-rectal-prolapse-is-associated-with-a-high-reoperation-rate
#6
T Rautio, J Mäkelä-Kaikkonen, M Vaarala, M Kairaluoma, J Kössi, M Carpelan-Holmström, S Salmenkylä, P Ohtonen, J Mäkelä
BACKGROUND: Laparoscopic ventral rectopexy has been used to treat male patients with external rectal prolapse, but evidence to support this approach is scarce. The aim of this study was to evaluate the results of this new abdominal rectopexy surgical technique in men. METHODS: This was a retrospective multicenter study. Adult male patients who were operated on for external rectal prolapse using ventral rectopexy in five tertiary hospitals in Finland between 2006 and 2014 were included in the study...
October 2016: Techniques in Coloproctology
https://www.readbyqxmd.com/read/27553198/outcome-of-laparoscopic-treatment-of-anorectal-malformations-in-children
#7
Sergey V Minaev, Igor V Kirgizov, Aleksander Gladkyy, Ilya Shishkin, Igor Gerasimenko
BACKGROUND: Operative correction of anorectal malformations (ARMs) remains a challenge in pediatric surgery. The study aimed to evaluate the outcomes of laparoscopic treatment of ARM in children. METHODS: From 2007 to 2014, we performed 104 laparoscopic-assisted anorectal pull-through procedures in children with a mean age of 11.3 ± 0.4 months and ARMs. Clinical assessment, surgical durations, complications, and postoperative outcome were investigated. RESULTS: The mean duration of the operation was 126...
August 23, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27487739/mesenteric-arteriovenous-dysplasia-vasculopathy-is-distinct-from-fibromuscular-dysplasia
#8
Deepa T Patil, Juliana Kissiedu, E Rene Rodriguez, Erinn Downs-Kelly, Xiuli Liu, Lisa A Rybicki, Carmela D Tan
Fibromuscular dysplasia (FMD) is a noninflammatory, nonatherosclerotic vasculopathy that usually affects the carotid and renal arteries. We have observed FMD-like vascular changes in specimens resected for ischemia or Crohn's disease (CD). On the basis of a systematic clinicopathologic review of these 11 cases identified between 1982 and 2014, we describe a distinct mesenteric vasculopathy that involves both arteries and veins [mesenteric arteriovenous dysplasia/vasculopathy (MAVD/V)] and is characterized by (1) concentric/eccentric smooth muscle collarette around the tunica media of both the artery and the vein in ≥2 foci, (2) varying degrees of intimal and medial hyperplasia and adventitial fibrosis, and (3) lack of inflammation or thrombi...
October 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27452753/-efficacy-and-safety-of-the-jinling-procedure-in-the-treatment-of-adult-hirschsprung-disease
#9
Bin Quan, Qiyi Chen, Jun Jiang, Ling Ni, Rongrong Tang, Yu Huang, Yifang Shi, Ning Li
OBJECTIVE: To investigate the safety, efficacy and long-term outcomes of Jinling procedure in the treatment of adult Hirschsprung disease. METHODS: Clinical and follow-up data of 125 patients with adult Hirschsprung disease undergoing Jinling procedure at the Department of General Surgery between January 2000 and January 2013 were summarized. All the patients were diagnosed by CT, barium enema, anorectal pressure detection and pathology examination. Abdominal symptoms, gastrointestinal quality of life index(GIQLI, the lower score, the worse quality of life), Wexner constipation score (higher score indicated worse symptom), defecography (evaluation included rectocele, mucosal prolapse, intramucosal intussusception, perineal prolapse) and other operative complications were compared before and after operation...
July 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27315791/benign-intestinal-glandular-lesions-in-the-vagina-a-possible-correlation-with-implantation
#10
Weiwei Lu, Xiaofei Zhang, Bingjian Lu
BACKGROUND: Enteric-type glandular lesions are extremely rare in the vagina. Their histological origin remains a matter of speculation at present. METHOD: We review two rectal mucosal prolapse-like polyps and one intestinal-type adenosis in the vagina. RESULTS: Case 1, a 64-year-old woman, presented with a vaginal polypoid lesion with a size of 4 × 3 × 3 cm. Case 2, an 8-year-old girl, had a 1.5 × 1.5 × 0.8-cm pedunculated polyp in the vaginal navicular fossa and a clinically suspected rectovaginal fistula...
2016: Diagnostic Pathology
https://www.readbyqxmd.com/read/27236579/sacral-nerve-stimulation-in-the-treatment-of-bowel-dysfunction-from-imperforate-anus-a-case-report
#11
Saleh M Eftaiha, George Melich, Ajit Pai, Slawomir J Marecik, Leela M Prasad, John J Park
INTRODUCTION: Bowel dysfunction (fecal incontinence and constipation) presents in over 50% of patients after treatment of congenital anal malformations. Sacral nerve stimulation (SNS) for the treatment of fecal incontinence improves function in the majority of patients. We present a case report of the treatment of bowel dysfunction with sacral nerve stimulation in a patient with a history of an imperforate anus. PRESENTATION OF CASE: A twenty year-old female with a history of imperforate anus at birth, repaired during infancy with anorectoplasty, presented with fecal incontinence and constipation...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27164931/hemorrhoid-laser-procedure-for-second-and-third-degree-hemorrhoids-results-from-a-multicenter-prospective-study
#12
P De Nardi, A M Tamburini, P G Gazzetta, M Lemma, A Pascariello, C R Asteria
BACKGROUND: The aim of our study was to assess the outcome of hemorrhoidal dearterialization, achieved by a dedicated laser energy device. METHODS: From November 2012 to December 2014, 51 patients with second- or third-degree hemorrhoids were studied. The primary end point was a reduction in the bleeding rate; secondary end points were: postoperative complications, reduction in pain and prolapse, resolution of symptoms, and degree of patient's perception of improvement...
July 2016: Techniques in Coloproctology
https://www.readbyqxmd.com/read/27063635/nonmuscle-myosin-iia-regulates-intestinal-epithelial-barrier-in-vivo-and-plays-a-protective-role-during-experimental-colitis
#13
Nayden G Naydenov, Alex Feygin, Dongdong Wang, John F Kuemmerle, Gianni Harris, Mary Anne Conti, Robert S Adelstein, Andrei I Ivanov
The actin cytoskeleton is a critical regulator of intestinal mucosal barrier permeability, and the integrity of epithelial adherens junctions (AJ) and tight junctions (TJ). Non muscle myosin II (NM II) is a key cytoskeletal motor that controls actin filament architecture and dynamics. While NM II has been implicated in the regulation of epithelial junctions in vitro, little is known about its roles in the intestinal mucosa in vivo. In this study, we generated a mouse model with an intestinal epithelial-specific knockout of NM IIA heavy chain (NM IIA cKO) and examined the structure and function of normal gut barrier, and the development of experimental colitis in these animals...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27003024/vaginal-fold-prolapse-in-a-dog-with-pyometra-and-ovarian-papillary-cystadenocarcinoma
#14
Maria-Teresa Zedda, Luisa Bogliolo, Federica Ariu, Mauro Ledda, Laura Falchi, Maria-Luisa Pinna-Parpaglia, Salvatore Pau
CASE DESCRIPTION: A 7-year-old 42-kg (92.4-lb) sexually intact nulliparous female Italian Mastiff was examined because of a history of vaginal prolapse during diestrus. CLINICAL FINDINGS: A physical examination revealed vaginal fold prolapse. Abdominal ultrasonography revealed an enlarged uterus with hypoechogenic content, corpora lutea in the ovaries, and a cyst in the right ovary. Hematologic abnormalities included leukocytosis, neutrophilia, mild anemia, and low Hct...
April 1, 2016: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/26997121/circular-mucosal-anopexy-experience-and-technical-considerations
#15
Luis Antonio Hidalgo Grau, Neus Ruiz Edo, Sara Llorca Cardeñosa, Adolfo Heredia Budó, Óscar Estrada Ferrer, Marta Del Bas Rubia, Eva María García Torralbo, Xavier Suñol Sala
INTRODUCTION: Circular mucosal anopexy (CMA) achieves a more comfortable postoperative period than resective techniques. But complications and recurrences are not infrequent. This study aims to evaluate of the efficacy of CMA in the treatment of hemorrhoids and rectal mucosal prolapse (RMP). METHOD: From 1999 to 2011, 613 patients underwent surgery for either hemorrhoids or RMP in our hospital. CMA was performed in 327 patients. Gender distribution was 196 male and 131 female...
May 2016: Cirugía Española
https://www.readbyqxmd.com/read/26989376/morphologic-basis-for-developing-diverticular-disease-diverticulitis-and-diverticular-bleeding
#16
REVIEW
Thilo Wedel, Martina Barrenschee, Christina Lange, François Cossais, Martina Böttner
Diverticula of the colon are pseudodiverticula defined by multiple outpouchings of the mucosal and submucosal layers penetrating through weak spots of the muscle coat along intramural blood vessels. A complete prolapse consists of a diverticular opening, a narrowed neck, and a thinned diverticular dome underneath the serosal covering. The susceptibility of diverticula to inflammation is explained by local ischemia, translocation of pathogens due to retained stool, stercoral trauma by fecaliths, and microperforations...
April 2015: Viszeralmedizin
https://www.readbyqxmd.com/read/26788482/inflammatory-septal-nasal-polyp
#17
Neha Salaria, Naveen Sharma, Uma Garg, Swaran Kaur Saluja, Ruchi Agarwal
INTRODUCTION: Nasal polyps are benign prolapsed mucosal lesions which commonly arise from the paranasal sinuses and lateral walls of the nose especially the contact areas of osteomeatal complex. Though nasal polyps arising from the nasal septum have been reported, those arising from its anterior part are extremely rare and present a diagnostic dilemma. Aetiology is multifactorial and is mainly a result of the inflammatory response of the lining mucosa. CASE REPORT: The case of a 28-year-old male, with a history of progressively increasing nasal complaints since 4 months and with a nasal mass arising from the anterior nasal septum on examination, is reported...
July 2015: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/26691359/solitary-rectal-ulcer-syndrome-demographic-clinical-endoscopic-and-histological-panorama
#18
Amanullah Abbasi, Abdul Rabb Bhutto, Ali Taj, Aurangzaib, Akhtar Baloch, Muhammad Masroor, S M Munir
OBJECTIVE: To assess the demographic, clinical, endoscopic and histological spectrum of Solitary Rectal Ulcer Syndrome (SRUS). STUDY DESIGN: Cross-sectional observational study. PLACE AND DURATION OF STUDY: Medical Unit-III, Civil Hospital Karachi (CHK) and Ward 7, Jinnah Postgraduate Medical Centre (JPMC), Karachi, from January 2009 to June 2012. METHODOLOGY: Patients with SRUS, based on characteristic endoscopic and histological findings, were enrolled...
December 2015: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/26618707/laparoscopic-suture-rectopexy-for-persistent-rectal-prolapse-in-children-is-it-a-safe-and-effective-first-line-intervention
#19
Karim Awad, Mohamed El Debeiky, Amr AbouZeid, Ayman Albaghdady, Tarek Hassan, Sameh Abdelhay
BACKGROUND: Several techniques have been described for the surgical correction of rectal prolapse without any clear advantage for one technique over the other. We evaluated the use of laparoscopic suture rectopexy (LSRP) as a modality of treatment for rectal prolapse in children. MATERIALS AND METHODS: Prospective data were collected for all children who presented to our center between 2011 and 2014 and required surgery for rectal prolapse. All children underwent LSRP with fixation of the mobilized rectum to the sacral promontory with multiple nonabsorbable sutures...
April 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/26599079/surgery-for-complete-full-thickness-rectal-prolapse-in-adults
#20
REVIEW
Samson Tou, Steven R Brown, Richard L Nelson
BACKGROUND: Complete (full-thickness) rectal prolapse is a lifestyle-altering disability that commonly affects older people. The range of surgical methods available to correct the underlying pelvic floor defects in full-thickness rectal prolapse reflects the lack of consensus regarding the best operation. OBJECTIVES: To assess the effects of different surgical repairs for complete (full-thickness) rectal prolapse. SEARCH METHODS: We searched the Cochrane Incontinence Group Specialised Register up to 3 February 2015; it contains trials from the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, MEDLINE in process, ClinicalTrials...
November 24, 2015: Cochrane Database of Systematic Reviews
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